TY  - JOUR
AU  - Vasiljević, Marko
AU  - Marinković, Darko
AU  - Milićević, Dragan
AU  - Pleadin, Jelka
AU  - Stefanović, Srđan
AU  - Trialović, Saša
AU  - Raj, Jog
AU  - Petrujkić, Branko
AU  - Trialović, Jelena Nedejković
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2230
PB  - MDPI
T2  - Toxins
T1  - Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens
VL  - 13
IS  - 7
SP  - 469
DO  - 10.3390/toxins13070469
ER  - 

@article{
author = "Vasiljević, Marko and Marinković, Darko and Milićević, Dragan and Pleadin, Jelka and Stefanović, Srđan and Trialović, Saša and Raj, Jog and Petrujkić, Branko and Trialović, Jelena Nedejković",
year = "2021",
publisher = "MDPI",
journal = "Toxins",
title = "Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens",
volume = "13",
number = "7",
pages = "469",
doi = "10.3390/toxins13070469"
}

Vasiljević, M., Marinković, D., Milićević, D., Pleadin, J., Stefanović, S., Trialović, S., Raj, J., Petrujkić, B.,& Trialović, J. N.. (2021). Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens. in Toxins
MDPI., 13(7), 469.
https://doi.org/10.3390/toxins13070469

Vasiljević M, Marinković D, Milićević D, Pleadin J, Stefanović S, Trialović S, Raj J, Petrujkić B, Trialović JN. Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens. in Toxins. 2021;13(7):469.
doi:10.3390/toxins13070469 .

Vasiljević, Marko, Marinković, Darko, Milićević, Dragan, Pleadin, Jelka, Stefanović, Srđan, Trialović, Saša, Raj, Jog, Petrujkić, Branko, Trialović, Jelena Nedejković, "Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens" in Toxins, 13, no. 7 (2021):469,
https://doi.org/10.3390/toxins13070469 . .

TY  - JOUR
AU  - Drašković, Vladimir
AU  - Bošnjak-Neumuller, Jasna
AU  - Vasiljević, Marko
AU  - Petrujkić, Branko
AU  - Aleksić, Nevenka
AU  - Kukolj, Vladimir
AU  - Stanimirović, Zoran
PY  - 2018
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1634
PB  - Elsevier Science Bv, Amsterdam
T2  - Preventive Veterinary Medicine
T1  - Influence of phytogenic feed additive on Lawsonia intracellularis infection in pigs (vol 151, pg 46, 2018)
VL  - 154
SP  - 29
EP  - 29
DO  - 10.1016/j.prevetmed.2018.03.007
ER  - 

@article{
author = "Drašković, Vladimir and Bošnjak-Neumuller, Jasna and Vasiljević, Marko and Petrujkić, Branko and Aleksić, Nevenka and Kukolj, Vladimir and Stanimirović, Zoran",
year = "2018",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Preventive Veterinary Medicine",
title = "Influence of phytogenic feed additive on Lawsonia intracellularis infection in pigs (vol 151, pg 46, 2018)",
volume = "154",
pages = "29-29",
doi = "10.1016/j.prevetmed.2018.03.007"
}

Drašković, V., Bošnjak-Neumuller, J., Vasiljević, M., Petrujkić, B., Aleksić, N., Kukolj, V.,& Stanimirović, Z.. (2018). Influence of phytogenic feed additive on Lawsonia intracellularis infection in pigs (vol 151, pg 46, 2018). in Preventive Veterinary Medicine
Elsevier Science Bv, Amsterdam., 154, 29-29.
https://doi.org/10.1016/j.prevetmed.2018.03.007

Drašković V, Bošnjak-Neumuller J, Vasiljević M, Petrujkić B, Aleksić N, Kukolj V, Stanimirović Z. Influence of phytogenic feed additive on Lawsonia intracellularis infection in pigs (vol 151, pg 46, 2018). in Preventive Veterinary Medicine. 2018;154:29-29.
doi:10.1016/j.prevetmed.2018.03.007 .

Drašković, Vladimir, Bošnjak-Neumuller, Jasna, Vasiljević, Marko, Petrujkić, Branko, Aleksić, Nevenka, Kukolj, Vladimir, Stanimirović, Zoran, "Influence of phytogenic feed additive on Lawsonia intracellularis infection in pigs (vol 151, pg 46, 2018)" in Preventive Veterinary Medicine, 154 (2018):29-29,
https://doi.org/10.1016/j.prevetmed.2018.03.007 . .

TY  - JOUR
AU  - Drašković, Vladimir
AU  - Bošnjak-Neumuller, Jasna
AU  - Vasiljević, Marko
AU  - Petrujkić, Branko
AU  - Aleksić, Nevenka
AU  - Kukolj, Vladimir
AU  - Stanimirović, Zoran
PY  - 2018
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1636
AB  - Lawsonia intracellularis is known to cause proliferative enteropathy (PE), one of the economically most important swine diseases with global distribution. Not unlike other enteric diseases, PE is a frequent indication for antibiotic therapy. However, their unjustified use leads to an emerging problem antimicrobial resistance. Thus, the aim of this research was to assess if a phytogenic additive may replace antibiotics in the control of PE in 144 weaned piglets (72 treated and 72 controls) naturally infected with L. intracellularis. The quantity of L intracellularis faecal shedding was monitored by real-time polymerase chain reaction (PCR) assay in faecal samples on day 0, 14 and 28, whilst the level of the ileum damage was determined by immunohistochemistry (IHC) assay performed on gut sections. Real-time PCR assay revealed that cycle-threshold (Ct) values in the treatment group increased significantly over time and were higher than in the control. These results indicate that the use of the phytogenic additive decreases the faecal excretion of L. intracellularis both throughout the experiment and in comparison to the control. The expression of the L. intracellularis antigen in IHC assay was lower in treated animals, implying that the additive leads to the decrease in the pathogen quantity in the ileum. Significantly higher feed conversion ratio was recorded in the treatment group. The results indicate that the phytogenic additive may be beneficial in the control of PE, but additional research is necessary to assess its use in various pig categories and define the optimum concentrations.
PB  - Elsevier Science Bv, Amsterdam
T2  - Preventive Veterinary Medicine
T1  - Influence of phytogenic feed additive on Lawsonia intracellularis infection in pigs
VL  - 151
SP  - 46
EP  - 51
DO  - 10.1016/j.prevetmed.2018.01.002
ER  - 

@article{
author = "Drašković, Vladimir and Bošnjak-Neumuller, Jasna and Vasiljević, Marko and Petrujkić, Branko and Aleksić, Nevenka and Kukolj, Vladimir and Stanimirović, Zoran",
year = "2018",
abstract = "Lawsonia intracellularis is known to cause proliferative enteropathy (PE), one of the economically most important swine diseases with global distribution. Not unlike other enteric diseases, PE is a frequent indication for antibiotic therapy. However, their unjustified use leads to an emerging problem antimicrobial resistance. Thus, the aim of this research was to assess if a phytogenic additive may replace antibiotics in the control of PE in 144 weaned piglets (72 treated and 72 controls) naturally infected with L. intracellularis. The quantity of L intracellularis faecal shedding was monitored by real-time polymerase chain reaction (PCR) assay in faecal samples on day 0, 14 and 28, whilst the level of the ileum damage was determined by immunohistochemistry (IHC) assay performed on gut sections. Real-time PCR assay revealed that cycle-threshold (Ct) values in the treatment group increased significantly over time and were higher than in the control. These results indicate that the use of the phytogenic additive decreases the faecal excretion of L. intracellularis both throughout the experiment and in comparison to the control. The expression of the L. intracellularis antigen in IHC assay was lower in treated animals, implying that the additive leads to the decrease in the pathogen quantity in the ileum. Significantly higher feed conversion ratio was recorded in the treatment group. The results indicate that the phytogenic additive may be beneficial in the control of PE, but additional research is necessary to assess its use in various pig categories and define the optimum concentrations.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Preventive Veterinary Medicine",
title = "Influence of phytogenic feed additive on Lawsonia intracellularis infection in pigs",
volume = "151",
pages = "46-51",
doi = "10.1016/j.prevetmed.2018.01.002"
}

Drašković, V., Bošnjak-Neumuller, J., Vasiljević, M., Petrujkić, B., Aleksić, N., Kukolj, V.,& Stanimirović, Z.. (2018). Influence of phytogenic feed additive on Lawsonia intracellularis infection in pigs. in Preventive Veterinary Medicine
Elsevier Science Bv, Amsterdam., 151, 46-51.
https://doi.org/10.1016/j.prevetmed.2018.01.002

Drašković V, Bošnjak-Neumuller J, Vasiljević M, Petrujkić B, Aleksić N, Kukolj V, Stanimirović Z. Influence of phytogenic feed additive on Lawsonia intracellularis infection in pigs. in Preventive Veterinary Medicine. 2018;151:46-51.
doi:10.1016/j.prevetmed.2018.01.002 .

Drašković, Vladimir, Bošnjak-Neumuller, Jasna, Vasiljević, Marko, Petrujkić, Branko, Aleksić, Nevenka, Kukolj, Vladimir, Stanimirović, Zoran, "Influence of phytogenic feed additive on Lawsonia intracellularis infection in pigs" in Preventive Veterinary Medicine, 151 (2018):46-51,
https://doi.org/10.1016/j.prevetmed.2018.01.002 . .

TY  - JOUR
AU  - Nedeljković-Trailović, Jelena
AU  - Trailović, Saša
AU  - Resanović, Radmila
AU  - Milićević, Dragan
AU  - Jovanović, Milijan
AU  - Vasiljević, Marko
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1193
AB  - The aim of our study was to determine the efficacy of three different adsorbents, inorganic (modified zeolite), organic (esterified glucomannans) and mixed (inorganic and organic components, with the addition of enzymes), in protecting broilers from the toxic effects of ochratoxin A in feed. Broilers were fed diets containing 2 mg/kg of ochratoxin A (OTA) and supplemented with adsorbents at the recommended concentration of 2 g/kg for 21 days. The presence of OTA led to a notable reduction in body weight, lower weight gain, increased feed conversion and induced histopathological changes in the liver and kidneys. The presence of inorganic, organic and mixed adsorbents in contaminated feed only partially reduced the negative effects of OTA on the broiler performances. Broilers that were fed with adsorbent-supplemented feed reached higher body weight (17.96%, 19.09% and 13.59%), compared to the group that received only OTA. The presence of adsorbents partially alleviated the reduction in feed consumption (22.68%, 12.91% and 10.59%), and a similar effect was observed with feed conversion. The applied adsorbents have also reduced the intensity of histopathological changes caused by OTA; however, they were not able to prevent their onset. After the withdrawal of the toxin and adsorbents from the feed (21-42 days), all previously observed disturbances in broilers were reduced, but more remarkably in broilers fed with adsorbents.
PB  - MDPI, Basel
T2  - Toxins
T1  - Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens
VL  - 7
IS  - 4
SP  - 1174
EP  - 1191
DO  - 10.3390/toxins7041174
ER  - 

@article{
author = "Nedeljković-Trailović, Jelena and Trailović, Saša and Resanović, Radmila and Milićević, Dragan and Jovanović, Milijan and Vasiljević, Marko",
year = "2015",
abstract = "The aim of our study was to determine the efficacy of three different adsorbents, inorganic (modified zeolite), organic (esterified glucomannans) and mixed (inorganic and organic components, with the addition of enzymes), in protecting broilers from the toxic effects of ochratoxin A in feed. Broilers were fed diets containing 2 mg/kg of ochratoxin A (OTA) and supplemented with adsorbents at the recommended concentration of 2 g/kg for 21 days. The presence of OTA led to a notable reduction in body weight, lower weight gain, increased feed conversion and induced histopathological changes in the liver and kidneys. The presence of inorganic, organic and mixed adsorbents in contaminated feed only partially reduced the negative effects of OTA on the broiler performances. Broilers that were fed with adsorbent-supplemented feed reached higher body weight (17.96%, 19.09% and 13.59%), compared to the group that received only OTA. The presence of adsorbents partially alleviated the reduction in feed consumption (22.68%, 12.91% and 10.59%), and a similar effect was observed with feed conversion. The applied adsorbents have also reduced the intensity of histopathological changes caused by OTA; however, they were not able to prevent their onset. After the withdrawal of the toxin and adsorbents from the feed (21-42 days), all previously observed disturbances in broilers were reduced, but more remarkably in broilers fed with adsorbents.",
publisher = "MDPI, Basel",
journal = "Toxins",
title = "Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens",
volume = "7",
number = "4",
pages = "1174-1191",
doi = "10.3390/toxins7041174"
}

Nedeljković-Trailović, J., Trailović, S., Resanović, R., Milićević, D., Jovanović, M.,& Vasiljević, M.. (2015). Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens. in Toxins
MDPI, Basel., 7(4), 1174-1191.
https://doi.org/10.3390/toxins7041174

Nedeljković-Trailović J, Trailović S, Resanović R, Milićević D, Jovanović M, Vasiljević M. Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens. in Toxins. 2015;7(4):1174-1191.
doi:10.3390/toxins7041174 .

Nedeljković-Trailović, Jelena, Trailović, Saša, Resanović, Radmila, Milićević, Dragan, Jovanović, Milijan, Vasiljević, Marko, "Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens" in Toxins, 7, no. 4 (2015):1174-1191,
https://doi.org/10.3390/toxins7041174 . .