TY  - JOUR
AU  - Janković, Dušan
AU  - Norrman, Johanna
AU  - Aronsson, Mia
AU  - Vojvodić, Danilo
AU  - Mirilović, Milorad
AU  - Vejnović, Branislav
AU  - Stanišić, Ljubodrag
AU  - Nedić, Svetlana
AU  - Maletić, Milan
AU  - Đurić, Miloje
AU  - Magaš, Vladimir
AU  - Vakanjac, Slobodanka
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2517
AB  - The work was aimed to research into the vital signs, haematological and biochemical parameters, acute-phase protein concentrations (CRP, albumin), progesterone (PG) and anti-Müllerian hormone (AMH) concentrations in bitches with pyometra and their comparison with those in healthy bitches. In addition, the goal of this work was to assess if some of the tested parameters may be used as a biomarker in the diagnostics of pyometra and the monitoring of the postoperative recovery. Forty 3-6-year-old bitches of various breeds were included in the research and allotted to two groups: the control (C, n = 20) and the diseased – bitches diagnosed with pyometra (P, n = 20). Blood samples for the analyses were taken immediately before surgery (0 h), and 12 h, 24 h, 48 h and 72 h after, excepting for AMH and PG concentrations, which were determined only at 0 h. Clinical examination detected significantly higher respiration rates in bitches with pyometra in comparison to healthy ones at all time points, higher heart rates before and 12 h after surgery, and higher body temperature before and 12 h, 48 h and 72 h post operation (p <.01). Significantly higher concentrations of CRP (p <.01) and lower concentrations of albumin were detected in bitches with pyometra in comparison to their healthy counterparts at all time points. Progesterone and AMH concentration analysis immediately before surgery detected significantly higher levels of the hormone in bitches with pyometra than in the control (p <.01). The inflammatory reaction of the endometrium resulted in a significant AMH concentration increase, whilst increased CRP concentrations and lower albumin concentrations throughout the research may be used as biomarkers of proinflammatory activities, that is of the acute-phase response.
PB  - John Wiley & Sons, Ltd
T2  - Reproduction in Domestic Animals
T1  - Analysis of the concentrations of some haematological parameters, C-reactive protein and anti-Müllerian hormone in bitches affected by pyometra
VL  - 57
IS  - 10
SP  - 1156
EP  - 1164
DO  - 10.1111/rda.14186
ER  - 

@article{
author = "Janković, Dušan and Norrman, Johanna and Aronsson, Mia and Vojvodić, Danilo and Mirilović, Milorad and Vejnović, Branislav and Stanišić, Ljubodrag and Nedić, Svetlana and Maletić, Milan and Đurić, Miloje and Magaš, Vladimir and Vakanjac, Slobodanka",
year = "2022",
abstract = "The work was aimed to research into the vital signs, haematological and biochemical parameters, acute-phase protein concentrations (CRP, albumin), progesterone (PG) and anti-Müllerian hormone (AMH) concentrations in bitches with pyometra and their comparison with those in healthy bitches. In addition, the goal of this work was to assess if some of the tested parameters may be used as a biomarker in the diagnostics of pyometra and the monitoring of the postoperative recovery. Forty 3-6-year-old bitches of various breeds were included in the research and allotted to two groups: the control (C, n = 20) and the diseased – bitches diagnosed with pyometra (P, n = 20). Blood samples for the analyses were taken immediately before surgery (0 h), and 12 h, 24 h, 48 h and 72 h after, excepting for AMH and PG concentrations, which were determined only at 0 h. Clinical examination detected significantly higher respiration rates in bitches with pyometra in comparison to healthy ones at all time points, higher heart rates before and 12 h after surgery, and higher body temperature before and 12 h, 48 h and 72 h post operation (p <.01). Significantly higher concentrations of CRP (p <.01) and lower concentrations of albumin were detected in bitches with pyometra in comparison to their healthy counterparts at all time points. Progesterone and AMH concentration analysis immediately before surgery detected significantly higher levels of the hormone in bitches with pyometra than in the control (p <.01). The inflammatory reaction of the endometrium resulted in a significant AMH concentration increase, whilst increased CRP concentrations and lower albumin concentrations throughout the research may be used as biomarkers of proinflammatory activities, that is of the acute-phase response.",
publisher = "John Wiley & Sons, Ltd",
journal = "Reproduction in Domestic Animals",
title = "Analysis of the concentrations of some haematological parameters, C-reactive protein and anti-Müllerian hormone in bitches affected by pyometra",
volume = "57",
number = "10",
pages = "1156-1164",
doi = "10.1111/rda.14186"
}

Janković, D., Norrman, J., Aronsson, M., Vojvodić, D., Mirilović, M., Vejnović, B., Stanišić, L., Nedić, S., Maletić, M., Đurić, M., Magaš, V.,& Vakanjac, S.. (2022). Analysis of the concentrations of some haematological parameters, C-reactive protein and anti-Müllerian hormone in bitches affected by pyometra. in Reproduction in Domestic Animals
John Wiley & Sons, Ltd., 57(10), 1156-1164.
https://doi.org/10.1111/rda.14186

Janković D, Norrman J, Aronsson M, Vojvodić D, Mirilović M, Vejnović B, Stanišić L, Nedić S, Maletić M, Đurić M, Magaš V, Vakanjac S. Analysis of the concentrations of some haematological parameters, C-reactive protein and anti-Müllerian hormone in bitches affected by pyometra. in Reproduction in Domestic Animals. 2022;57(10):1156-1164.
doi:10.1111/rda.14186 .

Janković, Dušan, Norrman, Johanna, Aronsson, Mia, Vojvodić, Danilo, Mirilović, Milorad, Vejnović, Branislav, Stanišić, Ljubodrag, Nedić, Svetlana, Maletić, Milan, Đurić, Miloje, Magaš, Vladimir, Vakanjac, Slobodanka, "Analysis of the concentrations of some haematological parameters, C-reactive protein and anti-Müllerian hormone in bitches affected by pyometra" in Reproduction in Domestic Animals, 57, no. 10 (2022):1156-1164,
https://doi.org/10.1111/rda.14186 . .