TY  - JOUR
AU  - Arsić, Miloš
AU  - Vićić, Ivan
AU  - Galić, Nataša
AU  - Dmitrić, Marko
AU  - Kureljušić, Jasna
AU  - Dimitrijević, Mirjana
AU  - Petrović, Miloš
AU  - Šarić, Ljubiša
AU  - Karabasil, Nedjeljko
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2496
AB  - A survey was undertaken to determine the overall prevalence of Yersinia enterocolitica in pigs of slaughter age and to characterize the isolates in relation to bio-serotype, the presence of virulence genes, genetic diversity, and antimicrobial resistance. Moreover, possible risk factors associated with Y. enterocolitica infection during the pre-harvested and harvested phase of pig production were studied. The overall Y. enterocolitica prevalence in the pigs was 10.4% (95% confidence interval, CI = 8.5–12.3%). The most common Y. enterocolitica bio-serotype was 4/O:3, accounting for 81.6% of investigated isolates. The pathogenicity of 63 Y. enterocolitica 4/O:3 isolates, originating from all infected farms, was confirmed by the presence of both the ail and ystA virulence-associated genes and the absence of ystB gene (100%). Characterization with PFGE of 63 confirmed Y. enterocolitica 4/O:3 isolates identified five different genotypes with shared identical genetic profiles (100% similarity) within each genotype. Isolates originating from farrow-to-finish farms were only resistant to ampicillin, while resistance to nalidixic acid, tetracycline, and chloramphenicol at fattening farms was also observed. Risk factors related to Y. enterocolitica pig infection include fattening farms (odds ratio, OR = 2.3, 95% CI = 1.4–3.8, P < 0.001), a 3–6 h lairage period (OR = 1.6, 95% CI = 1.0–2.6, P = 0.035) and winter season (OR = 3.8, 95% CI = 2.0–7.4, P < 0.001). In addition to the overall characterization of Y. enterocolitica isolates, identification of the main risks associated with infection allows better application of preventive measures to reduce the occurrence and distribution of Y. enterocolitica infection.
PB  - Elsevier
T2  - Research in Veterinary Science
T1  - Risk factors and the overall characterization of Yersinia enterocolitica as an initial model of pathogen surveillance in the pig production system in Serbia
VL  - 152
SP  - 167
EP  - 174
DO  - 10.1016/j.rvsc.2022.08.007
ER  - 

@article{
author = "Arsić, Miloš and Vićić, Ivan and Galić, Nataša and Dmitrić, Marko and Kureljušić, Jasna and Dimitrijević, Mirjana and Petrović, Miloš and Šarić, Ljubiša and Karabasil, Nedjeljko",
year = "2022",
abstract = "A survey was undertaken to determine the overall prevalence of Yersinia enterocolitica in pigs of slaughter age and to characterize the isolates in relation to bio-serotype, the presence of virulence genes, genetic diversity, and antimicrobial resistance. Moreover, possible risk factors associated with Y. enterocolitica infection during the pre-harvested and harvested phase of pig production were studied. The overall Y. enterocolitica prevalence in the pigs was 10.4% (95% confidence interval, CI = 8.5–12.3%). The most common Y. enterocolitica bio-serotype was 4/O:3, accounting for 81.6% of investigated isolates. The pathogenicity of 63 Y. enterocolitica 4/O:3 isolates, originating from all infected farms, was confirmed by the presence of both the ail and ystA virulence-associated genes and the absence of ystB gene (100%). Characterization with PFGE of 63 confirmed Y. enterocolitica 4/O:3 isolates identified five different genotypes with shared identical genetic profiles (100% similarity) within each genotype. Isolates originating from farrow-to-finish farms were only resistant to ampicillin, while resistance to nalidixic acid, tetracycline, and chloramphenicol at fattening farms was also observed. Risk factors related to Y. enterocolitica pig infection include fattening farms (odds ratio, OR = 2.3, 95% CI = 1.4–3.8, P < 0.001), a 3–6 h lairage period (OR = 1.6, 95% CI = 1.0–2.6, P = 0.035) and winter season (OR = 3.8, 95% CI = 2.0–7.4, P < 0.001). In addition to the overall characterization of Y. enterocolitica isolates, identification of the main risks associated with infection allows better application of preventive measures to reduce the occurrence and distribution of Y. enterocolitica infection.",
publisher = "Elsevier",
journal = "Research in Veterinary Science",
title = "Risk factors and the overall characterization of Yersinia enterocolitica as an initial model of pathogen surveillance in the pig production system in Serbia",
volume = "152",
pages = "167-174",
doi = "10.1016/j.rvsc.2022.08.007"
}

Arsić, M., Vićić, I., Galić, N., Dmitrić, M., Kureljušić, J., Dimitrijević, M., Petrović, M., Šarić, L.,& Karabasil, N.. (2022). Risk factors and the overall characterization of Yersinia enterocolitica as an initial model of pathogen surveillance in the pig production system in Serbia. in Research in Veterinary Science
Elsevier., 152, 167-174.
https://doi.org/10.1016/j.rvsc.2022.08.007

Arsić M, Vićić I, Galić N, Dmitrić M, Kureljušić J, Dimitrijević M, Petrović M, Šarić L, Karabasil N. Risk factors and the overall characterization of Yersinia enterocolitica as an initial model of pathogen surveillance in the pig production system in Serbia. in Research in Veterinary Science. 2022;152:167-174.
doi:10.1016/j.rvsc.2022.08.007 .

Arsić, Miloš, Vićić, Ivan, Galić, Nataša, Dmitrić, Marko, Kureljušić, Jasna, Dimitrijević, Mirjana, Petrović, Miloš, Šarić, Ljubiša, Karabasil, Nedjeljko, "Risk factors and the overall characterization of Yersinia enterocolitica as an initial model of pathogen surveillance in the pig production system in Serbia" in Research in Veterinary Science, 152 (2022):167-174,
https://doi.org/10.1016/j.rvsc.2022.08.007 . .