TY  - JOUR
AU  - Debeljak, Zoran
AU  - Boufana, Belgees
AU  - Interisano, Maria
AU  - Vidanović, Dejan
AU  - Kulišić, Zoran
AU  - Casulli, Adriano
PY  - 2016
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1404
AB  - Cystic echinococcosis (CE) caused by Echinococcus granulosus sensu stricto (s.s.) is a cosmopolitan zoonotic infection which is endemic in Serbia where it is subject to mandatory reporting. However, information on the incidence of the disease in humans and prevalence of hydatid infection in livestock remains limited. We used sequenced data of the cytochrome c oxidase subunit 1 (cox 1) mitochondrial gene to examine the genetic diversity and population structure of E. granulosus (s.s.) from intermediate hosts from Serbia. We also compared our generated nucleotide sequences with those reported for neighbouring European countries. Echinococcus canadensis was molecularly confirmed from pig and human hydatid isolates. E. granulosus (G1) was confirmed from sheep and cattle hydatid isolates as well as the first molecular confirmation in Serbia of E. granulosus G2 in sheep and E. granulosus G3 in sheep and cattle hydatid isolates. The Serbian E. granulosus (s.s.) parsimony network displayed 2 main haplotypes (SB02 and SB05) which together with the neutrality indices were suggestive of bottleneck and/or balancing selection. Haplotype analysis showed the presence of the common E. granulosus haplotype described from other worldwide regions. Investigation of the pairwise fixation (Fst) index suggested that Serbian populations of E. granulosus (s.s.) from sheep and cattle hosts showed moderate genetic differentiation. Six of the Serbian haplotypes (SB02-SB07) were shared with haplotypes from Bulgaria, Hungary and/or Romania. Further studies using a larger number of hydatid isolates from various locations across Serbia will provide more information on the genetic structure of E. granulosus (s.s.) within this region.
PB  - Elsevier Science Bv, Amsterdam
T2  - Veterinary Parasitology
T1  - First insights into the genetic diversity of Echinococcus granulosus sensu stricto (s.s.) in Serbia
VL  - 223
SP  - 57
EP  - 62
DO  - 10.1016/j.vetpar.2016.04.007
ER  - 

@article{
author = "Debeljak, Zoran and Boufana, Belgees and Interisano, Maria and Vidanović, Dejan and Kulišić, Zoran and Casulli, Adriano",
year = "2016",
abstract = "Cystic echinococcosis (CE) caused by Echinococcus granulosus sensu stricto (s.s.) is a cosmopolitan zoonotic infection which is endemic in Serbia where it is subject to mandatory reporting. However, information on the incidence of the disease in humans and prevalence of hydatid infection in livestock remains limited. We used sequenced data of the cytochrome c oxidase subunit 1 (cox 1) mitochondrial gene to examine the genetic diversity and population structure of E. granulosus (s.s.) from intermediate hosts from Serbia. We also compared our generated nucleotide sequences with those reported for neighbouring European countries. Echinococcus canadensis was molecularly confirmed from pig and human hydatid isolates. E. granulosus (G1) was confirmed from sheep and cattle hydatid isolates as well as the first molecular confirmation in Serbia of E. granulosus G2 in sheep and E. granulosus G3 in sheep and cattle hydatid isolates. The Serbian E. granulosus (s.s.) parsimony network displayed 2 main haplotypes (SB02 and SB05) which together with the neutrality indices were suggestive of bottleneck and/or balancing selection. Haplotype analysis showed the presence of the common E. granulosus haplotype described from other worldwide regions. Investigation of the pairwise fixation (Fst) index suggested that Serbian populations of E. granulosus (s.s.) from sheep and cattle hosts showed moderate genetic differentiation. Six of the Serbian haplotypes (SB02-SB07) were shared with haplotypes from Bulgaria, Hungary and/or Romania. Further studies using a larger number of hydatid isolates from various locations across Serbia will provide more information on the genetic structure of E. granulosus (s.s.) within this region.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Veterinary Parasitology",
title = "First insights into the genetic diversity of Echinococcus granulosus sensu stricto (s.s.) in Serbia",
volume = "223",
pages = "57-62",
doi = "10.1016/j.vetpar.2016.04.007"
}

Debeljak, Z., Boufana, B., Interisano, M., Vidanović, D., Kulišić, Z.,& Casulli, A.. (2016). First insights into the genetic diversity of Echinococcus granulosus sensu stricto (s.s.) in Serbia. in Veterinary Parasitology
Elsevier Science Bv, Amsterdam., 223, 57-62.
https://doi.org/10.1016/j.vetpar.2016.04.007

Debeljak Z, Boufana B, Interisano M, Vidanović D, Kulišić Z, Casulli A. First insights into the genetic diversity of Echinococcus granulosus sensu stricto (s.s.) in Serbia. in Veterinary Parasitology. 2016;223:57-62.
doi:10.1016/j.vetpar.2016.04.007 .

Debeljak, Zoran, Boufana, Belgees, Interisano, Maria, Vidanović, Dejan, Kulišić, Zoran, Casulli, Adriano, "First insights into the genetic diversity of Echinococcus granulosus sensu stricto (s.s.) in Serbia" in Veterinary Parasitology, 223 (2016):57-62,
https://doi.org/10.1016/j.vetpar.2016.04.007 . .