Žugić, Gordana

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Za i protiv primene antimikrobnih lekova kod koka nosilja konzumnih jaja

Ćupić, Vitomir; Ivanović, Saša; Borozan, Sunčica; Žugić, Gordana; Mujezinović, Indira; Ćupić Miladinović, Dejana; Aleksić, Jelena

(Beograd : Srpsko veterinarsko društvo, 2022) 

TY  - CONF
AU  - Ćupić, Vitomir
AU  - Ivanović, Saša
AU  - Borozan, Sunčica
AU  - Žugić, Gordana
AU  - Mujezinović, Indira
AU  - Ćupić Miladinović, Dejana
AU  - Aleksić, Jelena
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2689
AB  - Danas se antimikrobni lekovi u živinarstvu prvenstveno koriste za lečenje bolesti. U određenom broju zemalja, antimikrobni lekovi se primenjuju i kod koka nosilja konzumnih jaja, ali ima i onih (u koje se ubraja i naša), gde je njihova primena zabranjena.
U Evropskoj uniji je odobreno 6 antimikrobnih lekova za primenu kod koka nosilja konzumnih jaja. To su: kolistin, tilozin, neomicin, oksitetraciklin, hlortetraciklin i eritromicin. Uzimajući u obzir činjenicu da se ovi lekovi često koriste neracionalno, postoje velike šanse da će se njihovi ostaci, odnosno rezidue naći ne samo u mesu živine, već i u jajima u određenom periodu nakon prestanka lečenja. Pored lekova, koje je odobrila Evropska unija, rezidue navedenih lekova u jajima mogu biti rezultat pogrešno primenjene lekovite hrane, kontaminacije hrane nekim antimikrobnim lekom za vreme mešanja, kao i „extra-label“ upotrebe lekova kod živine. Antimikrobni lekovi se distribuiraju u organizmu i deponuju u jajima, uglavnom u žumancetu, gde se obično zadržavaju duže, u odnosu na belance. Lekovi koji se slabo resorbuju iz gastrointestinalnog trakta (aminoglikozidi, aminociklitoli, polimiksini) ne mogu se utvrditi u jajima, dok rezidue nekih antimikrobnih lekova, koji se resorbuju iz digestivnog trakta mogu perzistirati
u jajima i do dva meseca (npr. hloramfenikol) nakon poslednjeg tretmana. Racionalna upotreba lekova u veterinarskoj medicini ima višestruki značaj. Upotrebom svakog leka, samo onda kada je zaista neophodan (indikovan), u pravoj dozi i pravi način, ne samo da bi se smanjila potencijalna štetnost od njihove upotrebe, već bi se i povećala efikasnost i ono što je najvažnije, rizik od razvoja rezistencije kod mikroorganizama bi se značajno smanjio.
AB  - Today, antimicrobial drugs are primarily used for the prevention and treatment of poultry diseases, and often for growth stimulation in broilers. In a certain number of countries, antimicrobial drugs are also applied to laying hens, but there are also those, including our country, where their use is prohibited. In the European Union, 6 antimicrobial
drugs have been approved for use in laying hens. These are: colistin, tylosin, neomycin, oxytetracycline, chlortetracycline and erythromycin.
Taking into account the fact that these drugs are often used irrationally, there are great chances that their residues will be found not only in poultry meat, but also in eggs in a certain period after the cessation of treatment. In addition to drugs approved by the European Union, residues of the mentioned drugs in eggs can be the result of wrongly applied medicated feed, contamination of feed with some antimicrobial drug during mixing, as well as “extra-label” use of drugs in poultry. Antimicrobial drugs are distributed in the body and deposited in eggs, mainly in the yolk, where they usually stay longer, compared to the albumen. Drugs that are poorly absorbed from the gastrointestinal tract (aminoglycosides, aminocyclitols, polymyxins) cannot be determined in eggs, while the residues of some antimicrobial drugs, which are absorbed from the digestive tract, can be detected up to two months (e.g. chloramphenicol) after the last treatment.
The rational use of drugs in veterinary medicine has multiple importance. The use of each drug, only when it is really necessary (indicated), in the right dose and the right way, not only to reduce the potential harm from their use, but also to increase the effectiveness, and most importantly, the risk of developing resistance in of microorganisms
would be significantly reduced.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 33. Savetovanje veterinara Srbije, Zlatibor, 8-11. septembar 2022.
T1  - Za i protiv primene antimikrobnih lekova kod koka nosilja konzumnih jaja
T1  - The application of antimicrobial drugs in laying hens: for and against
SP  - 106
EP  - 112
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2689
ER  - 
@conference{
author = "Ćupić, Vitomir and Ivanović, Saša and Borozan, Sunčica and Žugić, Gordana and Mujezinović, Indira and Ćupić Miladinović, Dejana and Aleksić, Jelena",
year = "2022",
abstract = "Danas se antimikrobni lekovi u živinarstvu prvenstveno koriste za lečenje bolesti. U određenom broju zemalja, antimikrobni lekovi se primenjuju i kod koka nosilja konzumnih jaja, ali ima i onih (u koje se ubraja i naša), gde je njihova primena zabranjena.
U Evropskoj uniji je odobreno 6 antimikrobnih lekova za primenu kod koka nosilja konzumnih jaja. To su: kolistin, tilozin, neomicin, oksitetraciklin, hlortetraciklin i eritromicin. Uzimajući u obzir činjenicu da se ovi lekovi često koriste neracionalno, postoje velike šanse da će se njihovi ostaci, odnosno rezidue naći ne samo u mesu živine, već i u jajima u određenom periodu nakon prestanka lečenja. Pored lekova, koje je odobrila Evropska unija, rezidue navedenih lekova u jajima mogu biti rezultat pogrešno primenjene lekovite hrane, kontaminacije hrane nekim antimikrobnim lekom za vreme mešanja, kao i „extra-label“ upotrebe lekova kod živine. Antimikrobni lekovi se distribuiraju u organizmu i deponuju u jajima, uglavnom u žumancetu, gde se obično zadržavaju duže, u odnosu na belance. Lekovi koji se slabo resorbuju iz gastrointestinalnog trakta (aminoglikozidi, aminociklitoli, polimiksini) ne mogu se utvrditi u jajima, dok rezidue nekih antimikrobnih lekova, koji se resorbuju iz digestivnog trakta mogu perzistirati
u jajima i do dva meseca (npr. hloramfenikol) nakon poslednjeg tretmana. Racionalna upotreba lekova u veterinarskoj medicini ima višestruki značaj. Upotrebom svakog leka, samo onda kada je zaista neophodan (indikovan), u pravoj dozi i pravi način, ne samo da bi se smanjila potencijalna štetnost od njihove upotrebe, već bi se i povećala efikasnost i ono što je najvažnije, rizik od razvoja rezistencije kod mikroorganizama bi se značajno smanjio., Today, antimicrobial drugs are primarily used for the prevention and treatment of poultry diseases, and often for growth stimulation in broilers. In a certain number of countries, antimicrobial drugs are also applied to laying hens, but there are also those, including our country, where their use is prohibited. In the European Union, 6 antimicrobial
drugs have been approved for use in laying hens. These are: colistin, tylosin, neomycin, oxytetracycline, chlortetracycline and erythromycin.
Taking into account the fact that these drugs are often used irrationally, there are great chances that their residues will be found not only in poultry meat, but also in eggs in a certain period after the cessation of treatment. In addition to drugs approved by the European Union, residues of the mentioned drugs in eggs can be the result of wrongly applied medicated feed, contamination of feed with some antimicrobial drug during mixing, as well as “extra-label” use of drugs in poultry. Antimicrobial drugs are distributed in the body and deposited in eggs, mainly in the yolk, where they usually stay longer, compared to the albumen. Drugs that are poorly absorbed from the gastrointestinal tract (aminoglycosides, aminocyclitols, polymyxins) cannot be determined in eggs, while the residues of some antimicrobial drugs, which are absorbed from the digestive tract, can be detected up to two months (e.g. chloramphenicol) after the last treatment.
The rational use of drugs in veterinary medicine has multiple importance. The use of each drug, only when it is really necessary (indicated), in the right dose and the right way, not only to reduce the potential harm from their use, but also to increase the effectiveness, and most importantly, the risk of developing resistance in of microorganisms
would be significantly reduced.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "33. Savetovanje veterinara Srbije, Zlatibor, 8-11. septembar 2022.",
title = "Za i protiv primene antimikrobnih lekova kod koka nosilja konzumnih jaja, The application of antimicrobial drugs in laying hens: for and against",
pages = "106-112",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2689"
}
Ćupić, V., Ivanović, S., Borozan, S., Žugić, G., Mujezinović, I., Ćupić Miladinović, D.,& Aleksić, J.. (2022). Za i protiv primene antimikrobnih lekova kod koka nosilja konzumnih jaja. in 33. Savetovanje veterinara Srbije, Zlatibor, 8-11. septembar 2022.
Beograd : Srpsko veterinarsko društvo., 106-112.
https://hdl.handle.net/21.15107/rcub_veterinar_2689
Ćupić V, Ivanović S, Borozan S, Žugić G, Mujezinović I, Ćupić Miladinović D, Aleksić J. Za i protiv primene antimikrobnih lekova kod koka nosilja konzumnih jaja. in 33. Savetovanje veterinara Srbije, Zlatibor, 8-11. septembar 2022.. 2022;:106-112.
https://hdl.handle.net/21.15107/rcub_veterinar_2689 .
Ćupić, Vitomir, Ivanović, Saša, Borozan, Sunčica, Žugić, Gordana, Mujezinović, Indira, Ćupić Miladinović, Dejana, Aleksić, Jelena, "Za i protiv primene antimikrobnih lekova kod koka nosilja konzumnih jaja" in 33. Savetovanje veterinara Srbije, Zlatibor, 8-11. septembar 2022. (2022):106-112,
https://hdl.handle.net/21.15107/rcub_veterinar_2689 .