@article{
author = "Kayal, Advait and Stanley, Dragana and Radovanović, Anita and Horyanto, Darwin and Thi Thu, Thi Thu and Bajagai, Yadav S.",
year = "2022",
abstract = "The concept of designer microbiota in chicken is focused on early exposure of the hatchlings
to pathogen-free microbiota inoculum, limiting the early access to harmful and pathogenic
microorganisms, thus promoting colonisation of the gut with beneficial and natural poultry microbiota.
In this study, we controlled colonisation of the intestine in broiler chickens in a large-scale
industrial setting via at-hatch administration of a commercial product containing a highly diverse
microbiota originating from the chicken caecum. The treatment significantly transformed the microbiota
membership in the crop, proventriculus, jejunum and caecum and significantly altered the
taxa abundance in the jejunum, jejunum mucosa, and caecum estimated using PERMANOVA and
unweighted and weighted UniFrac distances, respectively. The treatment also improved the growth
rate in chickens with no significant alteration in feed conversion ratio. A comparison of inoculum
product microbiota structure revealed that the inoculum had the highest Shannon diversity index
compared to all investigated gut sections, and the number of Observed Species second only to the
caecal community. PCoA plots using weighted or unweighted UniFrac placed the inoculum samples
together with the samples from the caecal origin.",
publisher = "MDPI",
journal = "Animals",
title = "Controlled Intestinal Microbiota Colonisation in Broilers under the Industrial Production System",
volume = "12",
pages = "3296",
doi = "10.3390/ani12233296"
}