TY  - JOUR
AU  - Loncarić, Igor
AU  - Kuebber-Heiss, Anna
AU  - Posautz, Annika
AU  - Ruppitsch, Werner
AU  - Lepuschitz, Sarah
AU  - Schauer, Bernhard
AU  - Fessler, Andrea T.
AU  - Krametter-Froetscher, Reinhild
AU  - Harrison, Ewan M.
AU  - Holmes, Mark A.
AU  - Kuenzel, Frank
AU  - Szostak, Michael
AU  - Hauschild, Tomasz
AU  - Desvars-Larrive, Amelie
AU  - Mišić, Dušan
AU  - Rosengarten, Renate
AU  - Walzer, Chris
AU  - Slickers, Peter
AU  - Monecke, Stefan
AU  - Ehricht, Ralf
AU  - Schwarz, Stefan
AU  - Spergser, Joachim
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1775
AB  - The presence of the methicillin resistance gene mecC in coagulase-negative Staphylococcus spp. (CoNS) is scarce. The aim of this study was to characterize mecC-positive CoNS isolated from various wild and domestic animals. The presence of the mecC gene was screened in 4299 samples from wild animals and domestic animals. Fifteen coagulase-negative staphylococci, that displayed a cefoxitin-resistant phenotype, were tested mecC-positive by PCR. Antimicrobial susceptibility testing was performed for all isolates. The 15 isolates were genotyped by sequencing of the entire class E mec gene complex (blaZ-mecC-mecRI-mecI), the ccrA and ccrB recombinase genes and other determinants within the type XI SCCmec element. DNA microarray analysis was performed and five selected isolates were additionally whole genome sequenced and analyzed. S. stepanovicii (n = 3), S. caprae (n = 1), S. warneri (n = 1), S. xylosus (n = 1) and S. sciuri (n = 9) were detected. All but the S. sciuri isolates were found to be susceptible to all non-beta lactams. The entire class E mec gene complex was detected in all isolates but ccrA and ccrB genes were not identified in S. stepanovicii and S. xylosus. The genes erm(B) and fexA (n = 4, each) were the most predominant non-beta lactam resistance genes detected in the S. sciuri isolates. Even though the presence of the mecC gene among CoNS is a rare observation, this study further expands our knowledge by showing that the mecC gene, including its allotypes, are present in more staphylococcal species from different animal species than has been previously described.
PB  - Elsevier, Amsterdam
T2  - Veterinary Microbiology
T1  - Characterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animals
VL  - 230
SP  - 138
EP  - 144
DO  - 10.1016/j.vetmic.2019.02.014
ER  - 

@article{
author = "Loncarić, Igor and Kuebber-Heiss, Anna and Posautz, Annika and Ruppitsch, Werner and Lepuschitz, Sarah and Schauer, Bernhard and Fessler, Andrea T. and Krametter-Froetscher, Reinhild and Harrison, Ewan M. and Holmes, Mark A. and Kuenzel, Frank and Szostak, Michael and Hauschild, Tomasz and Desvars-Larrive, Amelie and Mišić, Dušan and Rosengarten, Renate and Walzer, Chris and Slickers, Peter and Monecke, Stefan and Ehricht, Ralf and Schwarz, Stefan and Spergser, Joachim",
year = "2019",
abstract = "The presence of the methicillin resistance gene mecC in coagulase-negative Staphylococcus spp. (CoNS) is scarce. The aim of this study was to characterize mecC-positive CoNS isolated from various wild and domestic animals. The presence of the mecC gene was screened in 4299 samples from wild animals and domestic animals. Fifteen coagulase-negative staphylococci, that displayed a cefoxitin-resistant phenotype, were tested mecC-positive by PCR. Antimicrobial susceptibility testing was performed for all isolates. The 15 isolates were genotyped by sequencing of the entire class E mec gene complex (blaZ-mecC-mecRI-mecI), the ccrA and ccrB recombinase genes and other determinants within the type XI SCCmec element. DNA microarray analysis was performed and five selected isolates were additionally whole genome sequenced and analyzed. S. stepanovicii (n = 3), S. caprae (n = 1), S. warneri (n = 1), S. xylosus (n = 1) and S. sciuri (n = 9) were detected. All but the S. sciuri isolates were found to be susceptible to all non-beta lactams. The entire class E mec gene complex was detected in all isolates but ccrA and ccrB genes were not identified in S. stepanovicii and S. xylosus. The genes erm(B) and fexA (n = 4, each) were the most predominant non-beta lactam resistance genes detected in the S. sciuri isolates. Even though the presence of the mecC gene among CoNS is a rare observation, this study further expands our knowledge by showing that the mecC gene, including its allotypes, are present in more staphylococcal species from different animal species than has been previously described.",
publisher = "Elsevier, Amsterdam",
journal = "Veterinary Microbiology",
title = "Characterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animals",
volume = "230",
pages = "138-144",
doi = "10.1016/j.vetmic.2019.02.014"
}

Loncarić, I., Kuebber-Heiss, A., Posautz, A., Ruppitsch, W., Lepuschitz, S., Schauer, B., Fessler, A. T., Krametter-Froetscher, R., Harrison, E. M., Holmes, M. A., Kuenzel, F., Szostak, M., Hauschild, T., Desvars-Larrive, A., Mišić, D., Rosengarten, R., Walzer, C., Slickers, P., Monecke, S., Ehricht, R., Schwarz, S.,& Spergser, J.. (2019). Characterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animals. in Veterinary Microbiology
Elsevier, Amsterdam., 230, 138-144.
https://doi.org/10.1016/j.vetmic.2019.02.014

Loncarić I, Kuebber-Heiss A, Posautz A, Ruppitsch W, Lepuschitz S, Schauer B, Fessler AT, Krametter-Froetscher R, Harrison EM, Holmes MA, Kuenzel F, Szostak M, Hauschild T, Desvars-Larrive A, Mišić D, Rosengarten R, Walzer C, Slickers P, Monecke S, Ehricht R, Schwarz S, Spergser J. Characterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animals. in Veterinary Microbiology. 2019;230:138-144.
doi:10.1016/j.vetmic.2019.02.014 .

Loncarić, Igor, Kuebber-Heiss, Anna, Posautz, Annika, Ruppitsch, Werner, Lepuschitz, Sarah, Schauer, Bernhard, Fessler, Andrea T., Krametter-Froetscher, Reinhild, Harrison, Ewan M., Holmes, Mark A., Kuenzel, Frank, Szostak, Michael, Hauschild, Tomasz, Desvars-Larrive, Amelie, Mišić, Dušan, Rosengarten, Renate, Walzer, Chris, Slickers, Peter, Monecke, Stefan, Ehricht, Ralf, Schwarz, Stefan, Spergser, Joachim, "Characterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animals" in Veterinary Microbiology, 230 (2019):138-144,
https://doi.org/10.1016/j.vetmic.2019.02.014 . .

TY  - JOUR
AU  - Loncarić, Igor
AU  - Kuebber-Heiss, Anna
AU  - Posautz, Annika
AU  - Ruppitsch, Werner
AU  - Lepuschitz, Sarah
AU  - Schauer, Bernhard
AU  - Fessler, Andrea T.
AU  - Krametter-Froetscher, Reinhild
AU  - Harrison, Ewan M.
AU  - Holmes, Mark A.
AU  - Kuenzel, Frank
AU  - Szostak, Michael
AU  - Hauschild, Tomasz
AU  - Desvars-Larrive, Amelie
AU  - Mišić, Dušan
AU  - Rosengarten, Renate
AU  - Walzer, Chris
AU  - Slickers, Peter
AU  - Monecke, Stefan
AU  - Ehricht, Ralf
AU  - Schwarz, Stefan
AU  - Spergser, Joachim
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1845
AB  - The presence of the methicillin resistance gene mecC in coagulase-negative Staphylococcus spp. (CoNS) is scarce. The aim of this study was to characterize mecC-positive CoNS isolated from various wild and domestic animals. The presence of the mecC gene was screened in 4299 samples from wild animals and domestic animals. Fifteen coagulase-negative staphylococci, that displayed a cefoxitin-resistant phenotype, were tested mecC-positive by PCR. Antimicrobial susceptibility testing was performed for all isolates. The 15 isolates were genotyped by sequencing of the entire class E mec gene complex (blaZ-mecC-mecRI-mecI), the ccrA and ccrB recombinase genes and other determinants within the type XI SCCmec element. DNA microarray analysis was performed and five selected isolates were additionally whole genome sequenced and analyzed. S. stepanovicii (n = 3), S. caprae (n = 1), S. warneri (n = 1), S. xylosus (n = 1) and S. sciuri (n = 9) were detected. All but the S. sciuri isolates were found to be susceptible to all non-beta lactams. The entire class E mec gene complex was detected in all isolates but ccrA and ccrB genes were not identified in S. stepanovicii and S. xylosus. The genes erm(B) and fexA (n = 4, each) were the most predominant non-beta lactam resistance genes detected in the S. sciuri isolates. Even though the presence of the mecC gene among CoNS is a rare observation, this study further expands our knowledge by showing that the mecC gene, including its allotypes, are present in more staphylococcal species from different animal species than has been previously described.
PB  - Elsevier, Amsterdam
T2  - Veterinary Microbiology
T1  - Characterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animals
VL  - 230
SP  - 138
EP  - 144
DO  - 10.1016/j.vetmic.2019.02.014
ER  - 

@article{
author = "Loncarić, Igor and Kuebber-Heiss, Anna and Posautz, Annika and Ruppitsch, Werner and Lepuschitz, Sarah and Schauer, Bernhard and Fessler, Andrea T. and Krametter-Froetscher, Reinhild and Harrison, Ewan M. and Holmes, Mark A. and Kuenzel, Frank and Szostak, Michael and Hauschild, Tomasz and Desvars-Larrive, Amelie and Mišić, Dušan and Rosengarten, Renate and Walzer, Chris and Slickers, Peter and Monecke, Stefan and Ehricht, Ralf and Schwarz, Stefan and Spergser, Joachim",
year = "2019",
abstract = "The presence of the methicillin resistance gene mecC in coagulase-negative Staphylococcus spp. (CoNS) is scarce. The aim of this study was to characterize mecC-positive CoNS isolated from various wild and domestic animals. The presence of the mecC gene was screened in 4299 samples from wild animals and domestic animals. Fifteen coagulase-negative staphylococci, that displayed a cefoxitin-resistant phenotype, were tested mecC-positive by PCR. Antimicrobial susceptibility testing was performed for all isolates. The 15 isolates were genotyped by sequencing of the entire class E mec gene complex (blaZ-mecC-mecRI-mecI), the ccrA and ccrB recombinase genes and other determinants within the type XI SCCmec element. DNA microarray analysis was performed and five selected isolates were additionally whole genome sequenced and analyzed. S. stepanovicii (n = 3), S. caprae (n = 1), S. warneri (n = 1), S. xylosus (n = 1) and S. sciuri (n = 9) were detected. All but the S. sciuri isolates were found to be susceptible to all non-beta lactams. The entire class E mec gene complex was detected in all isolates but ccrA and ccrB genes were not identified in S. stepanovicii and S. xylosus. The genes erm(B) and fexA (n = 4, each) were the most predominant non-beta lactam resistance genes detected in the S. sciuri isolates. Even though the presence of the mecC gene among CoNS is a rare observation, this study further expands our knowledge by showing that the mecC gene, including its allotypes, are present in more staphylococcal species from different animal species than has been previously described.",
publisher = "Elsevier, Amsterdam",
journal = "Veterinary Microbiology",
title = "Characterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animals",
volume = "230",
pages = "138-144",
doi = "10.1016/j.vetmic.2019.02.014"
}

Loncarić, I., Kuebber-Heiss, A., Posautz, A., Ruppitsch, W., Lepuschitz, S., Schauer, B., Fessler, A. T., Krametter-Froetscher, R., Harrison, E. M., Holmes, M. A., Kuenzel, F., Szostak, M., Hauschild, T., Desvars-Larrive, A., Mišić, D., Rosengarten, R., Walzer, C., Slickers, P., Monecke, S., Ehricht, R., Schwarz, S.,& Spergser, J.. (2019). Characterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animals. in Veterinary Microbiology
Elsevier, Amsterdam., 230, 138-144.
https://doi.org/10.1016/j.vetmic.2019.02.014

Loncarić I, Kuebber-Heiss A, Posautz A, Ruppitsch W, Lepuschitz S, Schauer B, Fessler AT, Krametter-Froetscher R, Harrison EM, Holmes MA, Kuenzel F, Szostak M, Hauschild T, Desvars-Larrive A, Mišić D, Rosengarten R, Walzer C, Slickers P, Monecke S, Ehricht R, Schwarz S, Spergser J. Characterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animals. in Veterinary Microbiology. 2019;230:138-144.
doi:10.1016/j.vetmic.2019.02.014 .

Loncarić, Igor, Kuebber-Heiss, Anna, Posautz, Annika, Ruppitsch, Werner, Lepuschitz, Sarah, Schauer, Bernhard, Fessler, Andrea T., Krametter-Froetscher, Reinhild, Harrison, Ewan M., Holmes, Mark A., Kuenzel, Frank, Szostak, Michael, Hauschild, Tomasz, Desvars-Larrive, Amelie, Mišić, Dušan, Rosengarten, Renate, Walzer, Chris, Slickers, Peter, Monecke, Stefan, Ehricht, Ralf, Schwarz, Stefan, Spergser, Joachim, "Characterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animals" in Veterinary Microbiology, 230 (2019):138-144,
https://doi.org/10.1016/j.vetmic.2019.02.014 . .

TY  - JOUR
AU  - Hauschild, Tomasz
AU  - Vuković, Dragana
AU  - Dakić, Ivana
AU  - Jezek, Petr
AU  - Đukić, Slobodanka
AU  - Dimitrijević, Vladimir
AU  - Stepanović, Srđan
AU  - Schwarz, Stefan
PY  - 2007
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/453
AB  - This study investigated the prevalence of aminoglycoside resistance and genes encoding aminoglycoside-modifying enzymes in members of the Staphylacoccus sciuri group. A total of 304 S. sciuri group member isolates (284 S. sciuri, 12 S. lentus, and 8 S. vitulinus) from humans (n=34), animals (n=133), and environmental sources (n=137; out-hospital and hospital environment, food) were examined for their susceptibility to amikacin, gentamicin, isepamicin, kanamycin, neomycin, netilmicin, sisomicin, streptomycin, and tobramycin. The overall prevalence of resistance to aminoglycosides was low at 12.1%. Resistance to single aminoglycosides ranged from 0% to 7.2%. The aac(6)-Ie/aph(2 ), ant(4)-Ia, and aph(3)-IIIa genes, either alone or in combination, were found in 16 out of 19 isolates showing resistance to nonstreptomycin aminoglycosides. Among the 22 isolates that showed resistance to streptomycin, the genes str and ant(6)-Ia were identified in 18 and 4 isolates, respectively.
PB  - Mary Ann Liebert, Inc, New Rochelle
T2  - Microbial Drug Resistance
T1  - Aminoglycoside resistance in members of the Staphylococcus sciuri group
VL  - 13
IS  - 2
SP  - 77
EP  - 84
DO  - 10.1089/mdr.2007.713
ER  - 

@article{
author = "Hauschild, Tomasz and Vuković, Dragana and Dakić, Ivana and Jezek, Petr and Đukić, Slobodanka and Dimitrijević, Vladimir and Stepanović, Srđan and Schwarz, Stefan",
year = "2007",
abstract = "This study investigated the prevalence of aminoglycoside resistance and genes encoding aminoglycoside-modifying enzymes in members of the Staphylacoccus sciuri group. A total of 304 S. sciuri group member isolates (284 S. sciuri, 12 S. lentus, and 8 S. vitulinus) from humans (n=34), animals (n=133), and environmental sources (n=137; out-hospital and hospital environment, food) were examined for their susceptibility to amikacin, gentamicin, isepamicin, kanamycin, neomycin, netilmicin, sisomicin, streptomycin, and tobramycin. The overall prevalence of resistance to aminoglycosides was low at 12.1%. Resistance to single aminoglycosides ranged from 0% to 7.2%. The aac(6)-Ie/aph(2 ), ant(4)-Ia, and aph(3)-IIIa genes, either alone or in combination, were found in 16 out of 19 isolates showing resistance to nonstreptomycin aminoglycosides. Among the 22 isolates that showed resistance to streptomycin, the genes str and ant(6)-Ia were identified in 18 and 4 isolates, respectively.",
publisher = "Mary Ann Liebert, Inc, New Rochelle",
journal = "Microbial Drug Resistance",
title = "Aminoglycoside resistance in members of the Staphylococcus sciuri group",
volume = "13",
number = "2",
pages = "77-84",
doi = "10.1089/mdr.2007.713"
}

Hauschild, T., Vuković, D., Dakić, I., Jezek, P., Đukić, S., Dimitrijević, V., Stepanović, S.,& Schwarz, S.. (2007). Aminoglycoside resistance in members of the Staphylococcus sciuri group. in Microbial Drug Resistance
Mary Ann Liebert, Inc, New Rochelle., 13(2), 77-84.
https://doi.org/10.1089/mdr.2007.713

Hauschild T, Vuković D, Dakić I, Jezek P, Đukić S, Dimitrijević V, Stepanović S, Schwarz S. Aminoglycoside resistance in members of the Staphylococcus sciuri group. in Microbial Drug Resistance. 2007;13(2):77-84.
doi:10.1089/mdr.2007.713 .

Hauschild, Tomasz, Vuković, Dragana, Dakić, Ivana, Jezek, Petr, Đukić, Slobodanka, Dimitrijević, Vladimir, Stepanović, Srđan, Schwarz, Stefan, "Aminoglycoside resistance in members of the Staphylococcus sciuri group" in Microbial Drug Resistance, 13, no. 2 (2007):77-84,
https://doi.org/10.1089/mdr.2007.713 . .