TY  - JOUR
AU  - Petrov, Elena Atanaskova
AU  - Celeska, Irena
AU  - Popova, Zagorka
AU  - Krstevski, Kiril
AU  - Djadjovski, Igor
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2203
AB  - Canine monocytic ehrlichiosis (CME) is a widespread, tick-borne, canine disease, caused by an obligate intracellular bacterium, Ehrlichia canis. The main vector, a brown-dog tick, Rhipicephalus sanguineus, is widely distributed, especially in areas with tropic, subtropic, or Mediterranean climates (Central and South America, Eastern and Western Asia, Africa, Australia and Southern Europe). The study performed in 2012, by Stefanovska et al., determined a seroprevalence of 18.7% of E. canis among the Macedonian dog population. Up to date, the presence of E. canis, using molecular diagnostic methods, has not been investigated in Macedonia. Therefore, this study aimed to confirm the presence of E. canis, in the pet-dog population on the territory of the city of Skopje, North Macedonia, using a highly sensitive multiplex Real-Time PCR method (qPCR). Whole blood samples from 80 dogs of different breeds and ages, with clinical symptoms of CME and positive serology result for the presence of antibodies against E.canis, were collected for analyses. Out of 80 dogs, 36 (45%) were found as positive. The present work reports the first molecular detection of E. canis in pet dogs on the territory of the city of Skopje, Macedonia.
AB  - Monocitna erlihioza pasa (CME) je široko rasprostranjena bolest pasa, koja se prenosi krpeljima, a uzrokuje je obligatno-intracelularna bakterija Ehrlichia canis. Glavni vektor, smeđi krpelj pasa, Rhipicephalus sanguineus, široko je rasprostranjen, posebno u oblastima sa tropskom, subtropskom ili mediteranskom klimom (Centralna i Južna Amerika, Istočna i Zapadna Azija, Afrika, Australija i Južna Evropa). U Studiji izvedenoj 2012. godine, Stefanovska i saradnici su utvrdili da među severnomakedonskom populacijom pasa, seroprevalencija E. canis iznosi 18,7%. Do danas, prisustvo E. canis, koristeć i molekularne dijagnostičke metode, nije istraženo u Severnoj Makedoniji. Stoga je ova studija imala za cilj da potvrdi prisustvo E. canis u populaciji kuć nih ljubimaca na teritoriji grada Skoplja u Severnoj Makedoniji, koristeć i visoko osetljivu multiplex Real-Time PCR (qPCR). Za analize su prikupljeni uzorci pune krvi od 80 pasa različitih rasa i uzrasta, sa kliničkim simptomima CME i pozitivnim serološkim rezultatom na prisustvo antitela protiv E.canis. Od 80 pasa, 36 (45%) je ocenjeno kao pozitivno. Ovaj rad izveštava o prvom molekularnom otkrivanju E. canis kod pasa kuć nih ljubimaca na teritoriji grada Skoplja, Severna Makedonija.
T2  - Acta Veterinaria-Beograd
T1  - Molecular Detection of in the Pet-Dog Population in R. N. Macedonia
T1  - Molekularna detekcija ehrlichia canis u populaciji pasa -kućnih ljubimaca u Severnoj Makedoniji
VL  - 71
IS  - 2
SP  - 230
EP  - 238
DO  - 10.2478/acve-2021-0020
ER  - 

@article{
author = "Petrov, Elena Atanaskova and Celeska, Irena and Popova, Zagorka and Krstevski, Kiril and Djadjovski, Igor",
year = "2021",
abstract = "Canine monocytic ehrlichiosis (CME) is a widespread, tick-borne, canine disease, caused by an obligate intracellular bacterium, Ehrlichia canis. The main vector, a brown-dog tick, Rhipicephalus sanguineus, is widely distributed, especially in areas with tropic, subtropic, or Mediterranean climates (Central and South America, Eastern and Western Asia, Africa, Australia and Southern Europe). The study performed in 2012, by Stefanovska et al., determined a seroprevalence of 18.7% of E. canis among the Macedonian dog population. Up to date, the presence of E. canis, using molecular diagnostic methods, has not been investigated in Macedonia. Therefore, this study aimed to confirm the presence of E. canis, in the pet-dog population on the territory of the city of Skopje, North Macedonia, using a highly sensitive multiplex Real-Time PCR method (qPCR). Whole blood samples from 80 dogs of different breeds and ages, with clinical symptoms of CME and positive serology result for the presence of antibodies against E.canis, were collected for analyses. Out of 80 dogs, 36 (45%) were found as positive. The present work reports the first molecular detection of E. canis in pet dogs on the territory of the city of Skopje, Macedonia., Monocitna erlihioza pasa (CME) je široko rasprostranjena bolest pasa, koja se prenosi krpeljima, a uzrokuje je obligatno-intracelularna bakterija Ehrlichia canis. Glavni vektor, smeđi krpelj pasa, Rhipicephalus sanguineus, široko je rasprostranjen, posebno u oblastima sa tropskom, subtropskom ili mediteranskom klimom (Centralna i Južna Amerika, Istočna i Zapadna Azija, Afrika, Australija i Južna Evropa). U Studiji izvedenoj 2012. godine, Stefanovska i saradnici su utvrdili da među severnomakedonskom populacijom pasa, seroprevalencija E. canis iznosi 18,7%. Do danas, prisustvo E. canis, koristeć i molekularne dijagnostičke metode, nije istraženo u Severnoj Makedoniji. Stoga je ova studija imala za cilj da potvrdi prisustvo E. canis u populaciji kuć nih ljubimaca na teritoriji grada Skoplja u Severnoj Makedoniji, koristeć i visoko osetljivu multiplex Real-Time PCR (qPCR). Za analize su prikupljeni uzorci pune krvi od 80 pasa različitih rasa i uzrasta, sa kliničkim simptomima CME i pozitivnim serološkim rezultatom na prisustvo antitela protiv E.canis. Od 80 pasa, 36 (45%) je ocenjeno kao pozitivno. Ovaj rad izveštava o prvom molekularnom otkrivanju E. canis kod pasa kuć nih ljubimaca na teritoriji grada Skoplja, Severna Makedonija.",
journal = "Acta Veterinaria-Beograd",
title = "Molecular Detection of in the Pet-Dog Population in R. N. Macedonia, Molekularna detekcija ehrlichia canis u populaciji pasa -kućnih ljubimaca u Severnoj Makedoniji",
volume = "71",
number = "2",
pages = "230-238",
doi = "10.2478/acve-2021-0020"
}

Petrov, E. A., Celeska, I., Popova, Z., Krstevski, K.,& Djadjovski, I.. (2021). Molecular Detection of in the Pet-Dog Population in R. N. Macedonia. in Acta Veterinaria-Beograd, 71(2), 230-238.
https://doi.org/10.2478/acve-2021-0020

Petrov EA, Celeska I, Popova Z, Krstevski K, Djadjovski I. Molecular Detection of in the Pet-Dog Population in R. N. Macedonia. in Acta Veterinaria-Beograd. 2021;71(2):230-238.
doi:10.2478/acve-2021-0020 .

Petrov, Elena Atanaskova, Celeska, Irena, Popova, Zagorka, Krstevski, Kiril, Djadjovski, Igor, "Molecular Detection of in the Pet-Dog Population in R. N. Macedonia" in Acta Veterinaria-Beograd, 71, no. 2 (2021):230-238,
https://doi.org/10.2478/acve-2021-0020 . .

TY  - JOUR
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Korićanac, Goran
AU  - Bojkovski, Jovan
AU  - Simeunović, Predrag
AU  - Palamarević, Milija
AU  - Nedić, Sreten
AU  - Celeska, Irena
AU  - Kirovski, Danijela
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1536
AB  - This study aimed to evaluate glucose-induced insulin response in cows exposed to different temperature-humidity index. Twenty early lactating Holstein-Friesian cows were divided into 2 equal groups based on season, as summer (SU) and spring (SP). SP cows were not exposed to heat stress, while SU cows were exposed to moderate or severe heat stress. Milk production was recorded daily. Starting from day 30 of lactation, intravenous glucose tolerance test (IVGTT) was carried out three times at 30-day intervals. Blood samples were taken before (basal) and after glucose infusion, and glucose and insulin were measured at each sample point. The homeostatic model assessment (HOMA) index was calculated. Milk yield from days 30 to 40 and 64 to 90 of lactation were higher in SP cows than in SU cows. Basal glucose did not differ on days 30 and 60 of lactation, while basal insulin and HOMA were lower in SU compared to SP cows. On day 90 of lactation, SU cows had higher basal glucose, whereas basal insulin and HOMA did not differ. IVGTT results revealed that glucose tolerance was affected by heat stress such that SU cows had higher glucose clearance. Insulin responses to IVGTT did not differ on days 30 and 60 of lactation. Heat stress had a marked effect on insulin secretion on day 90 of lactation, illustrated by higher increments, peak concentrations and area under the curve for insulin in SU cows. Overall, season differences in glucose tolerance depend not only on heat stress and milk production but also on the stage of lactation.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Field trial on glucose-induced insulin response in high-yielding dairy cows under different environmental temperatures
VL  - 67
IS  - 3
SP  - 366
EP  - 382
DO  - 10.1515/acve-2017-0030
ER  - 

@article{
author = "Vujanac, Ivan and Prodanović, Radiša and Korićanac, Goran and Bojkovski, Jovan and Simeunović, Predrag and Palamarević, Milija and Nedić, Sreten and Celeska, Irena and Kirovski, Danijela",
year = "2017",
abstract = "This study aimed to evaluate glucose-induced insulin response in cows exposed to different temperature-humidity index. Twenty early lactating Holstein-Friesian cows were divided into 2 equal groups based on season, as summer (SU) and spring (SP). SP cows were not exposed to heat stress, while SU cows were exposed to moderate or severe heat stress. Milk production was recorded daily. Starting from day 30 of lactation, intravenous glucose tolerance test (IVGTT) was carried out three times at 30-day intervals. Blood samples were taken before (basal) and after glucose infusion, and glucose and insulin were measured at each sample point. The homeostatic model assessment (HOMA) index was calculated. Milk yield from days 30 to 40 and 64 to 90 of lactation were higher in SP cows than in SU cows. Basal glucose did not differ on days 30 and 60 of lactation, while basal insulin and HOMA were lower in SU compared to SP cows. On day 90 of lactation, SU cows had higher basal glucose, whereas basal insulin and HOMA did not differ. IVGTT results revealed that glucose tolerance was affected by heat stress such that SU cows had higher glucose clearance. Insulin responses to IVGTT did not differ on days 30 and 60 of lactation. Heat stress had a marked effect on insulin secretion on day 90 of lactation, illustrated by higher increments, peak concentrations and area under the curve for insulin in SU cows. Overall, season differences in glucose tolerance depend not only on heat stress and milk production but also on the stage of lactation.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Field trial on glucose-induced insulin response in high-yielding dairy cows under different environmental temperatures",
volume = "67",
number = "3",
pages = "366-382",
doi = "10.1515/acve-2017-0030"
}

Vujanac, I., Prodanović, R., Korićanac, G., Bojkovski, J., Simeunović, P., Palamarević, M., Nedić, S., Celeska, I.,& Kirovski, D.. (2017). Field trial on glucose-induced insulin response in high-yielding dairy cows under different environmental temperatures. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 67(3), 366-382.
https://doi.org/10.1515/acve-2017-0030

Vujanac I, Prodanović R, Korićanac G, Bojkovski J, Simeunović P, Palamarević M, Nedić S, Celeska I, Kirovski D. Field trial on glucose-induced insulin response in high-yielding dairy cows under different environmental temperatures. in Acta Veterinaria-Beograd. 2017;67(3):366-382.
doi:10.1515/acve-2017-0030 .

Vujanac, Ivan, Prodanović, Radiša, Korićanac, Goran, Bojkovski, Jovan, Simeunović, Predrag, Palamarević, Milija, Nedić, Sreten, Celeska, Irena, Kirovski, Danijela, "Field trial on glucose-induced insulin response in high-yielding dairy cows under different environmental temperatures" in Acta Veterinaria-Beograd, 67, no. 3 (2017):366-382,
https://doi.org/10.1515/acve-2017-0030 . .

TY  - JOUR
AU  - Kukovska, Valentina
AU  - Celeska, Irena
AU  - Ruskovska, Tatjana
AU  - Valčić, Olivera
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1284
AB  - The aim of this study was to evaluate the effects of 60 days of rose-hip and grapeseed dietary supplementation of a balanced home-cooked diet on serum oxidative stress parameters: ROMs, MDA and FRAP in army service dogs before and after regular physical exercise. The dogs were fed a balanced cooked diet as instructed by army standards until the initial blood sampling in June. Thereon the dogs were randomly allotted to 4 groups according to the dietary regime: dogs maintained on a balanced cooked diet according to army standards, branded dry dog food, cooked diet with added 500 mg rose-hip extract, and cooked diet with added 100 mg grapeseed extract for a 60 day period from June to September after which all 4 groups were fed the standard cooked meal diet. Sampling was performed at the beginning of the experiment (June), 60 days from the start of the treatment (September) and finally 60 days after the end of supplementation (November). Statistical analysis of the results included descriptive statistical parameters: mean (M), standard deviation (SD), and variation coefficient (CV%). In order to test the statistical significance of the differences between treatments a multifactor variance test (ANOVA) was performed for ROM, MDA and FRAP and the combined effects of diet, exercise and time period were observed. The initial (in June) increase in MDA and ROMs after exercise indicates the presence of oxidative stress 30 minutes after exercise. However, the antioxidative effects of rose-hip and grapeseed extracts are not conclusive, as multifactor ANOVA testing of time, diet, and exercise factors did not reveal for MDA statistically significant differences either at 60 days of supplementation nor 60 days after withdrawal of the supplements. Only one distinct exception was recorded for the prolonged antioxidative effects reflected in significantly decreased (p < 0.01) ROMs before and after exercise in dogs fed the branded dry food 60 days after the end of such dietary regime (November). FRAP values tend to be higher (p > 0.05) after exercise compared to before exercise in all experimental groups in November, indicating on a possible redistribution and upregulation of endogenous antioxidants during the experiment.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Effects of rose-hip and grapeseed dietary supplementation on serum oxidative stress parameters in dogs before and after physical exercise
VL  - 65
IS  - 3
SP  - 404
EP  - 416
DO  - 10.1515/acve-2015-0033
ER  - 

@article{
author = "Kukovska, Valentina and Celeska, Irena and Ruskovska, Tatjana and Valčić, Olivera",
year = "2015",
abstract = "The aim of this study was to evaluate the effects of 60 days of rose-hip and grapeseed dietary supplementation of a balanced home-cooked diet on serum oxidative stress parameters: ROMs, MDA and FRAP in army service dogs before and after regular physical exercise. The dogs were fed a balanced cooked diet as instructed by army standards until the initial blood sampling in June. Thereon the dogs were randomly allotted to 4 groups according to the dietary regime: dogs maintained on a balanced cooked diet according to army standards, branded dry dog food, cooked diet with added 500 mg rose-hip extract, and cooked diet with added 100 mg grapeseed extract for a 60 day period from June to September after which all 4 groups were fed the standard cooked meal diet. Sampling was performed at the beginning of the experiment (June), 60 days from the start of the treatment (September) and finally 60 days after the end of supplementation (November). Statistical analysis of the results included descriptive statistical parameters: mean (M), standard deviation (SD), and variation coefficient (CV%). In order to test the statistical significance of the differences between treatments a multifactor variance test (ANOVA) was performed for ROM, MDA and FRAP and the combined effects of diet, exercise and time period were observed. The initial (in June) increase in MDA and ROMs after exercise indicates the presence of oxidative stress 30 minutes after exercise. However, the antioxidative effects of rose-hip and grapeseed extracts are not conclusive, as multifactor ANOVA testing of time, diet, and exercise factors did not reveal for MDA statistically significant differences either at 60 days of supplementation nor 60 days after withdrawal of the supplements. Only one distinct exception was recorded for the prolonged antioxidative effects reflected in significantly decreased (p < 0.01) ROMs before and after exercise in dogs fed the branded dry food 60 days after the end of such dietary regime (November). FRAP values tend to be higher (p > 0.05) after exercise compared to before exercise in all experimental groups in November, indicating on a possible redistribution and upregulation of endogenous antioxidants during the experiment.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Effects of rose-hip and grapeseed dietary supplementation on serum oxidative stress parameters in dogs before and after physical exercise",
volume = "65",
number = "3",
pages = "404-416",
doi = "10.1515/acve-2015-0033"
}

Kukovska, V., Celeska, I., Ruskovska, T.,& Valčić, O.. (2015). Effects of rose-hip and grapeseed dietary supplementation on serum oxidative stress parameters in dogs before and after physical exercise. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 65(3), 404-416.
https://doi.org/10.1515/acve-2015-0033

Kukovska V, Celeska I, Ruskovska T, Valčić O. Effects of rose-hip and grapeseed dietary supplementation on serum oxidative stress parameters in dogs before and after physical exercise. in Acta Veterinaria-Beograd. 2015;65(3):404-416.
doi:10.1515/acve-2015-0033 .

Kukovska, Valentina, Celeska, Irena, Ruskovska, Tatjana, Valčić, Olivera, "Effects of rose-hip and grapeseed dietary supplementation on serum oxidative stress parameters in dogs before and after physical exercise" in Acta Veterinaria-Beograd, 65, no. 3 (2015):404-416,
https://doi.org/10.1515/acve-2015-0033 . .

TY  - JOUR
AU  - Dzadzovski, Igor
AU  - Celeska, Irena
AU  - Ulchar, Igor
AU  - Janevski, Aleksandar
AU  - Kirovski, Danijela
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1263
AB  - Chios is a breed of sheep selected for milk production, with metabolic features typical for a dairy sheep breed. The energy requirements of pregnant sheep is increase in the last weeks of gestation. Metabolic imbalance in the late pregnancy in sheep, usually cause a metabolic disorder known as pregnancy toxemia. Additionally, a pregnant sheep exposed to low environmental temperatures has increased energy demands, due to its adaptation to undesirable environmental conditions. The aim of this study was to compare the metabolic profile of Chios sheep exposed to different environmental conditions. Two groups of ewes were instigated. First group included 8 pregnant ewes with clinical signs of pregnancy toxemia exposed to cold stress during the winter season. The second group included 8 non-pregnant, clinically healthy ewes, that were examined during the non-breeding period, in the spring season. Blood samples were taken and serum concentrations of glucose, beta-hydroxybutirate (BHBA), total protein, albumin, urea, creatinine, triglyceride and cholesterol, as well as activity of AST and ALP were determined. Pregnant ewes exposed to cold stress had significantly lower levels of glucose and total protein, and significantly higher levels of BHBA, albumin and AST in the serum compared to non-pregnant ewes that were in optimal environmental conditions. There was no significant difference between the serum levels of urea, creatinine, cholesterol, triglycerides and ALP among the groups. In conclusion, low environmental temperature and poor feeding during the winter season caused metabolic distress in pregnant ewes during the early winter season.
PB  - Univ Sv Kiril & Metodij Skopje, Fak Veterinarna Medicina, Skopje
T2  - Macedonian Veterinary Review
T1  - Influence of the season on the metabolic profile in chios sheep
VL  - 38
IS  - 2
SP  - 183
EP  - 188
DO  - 10.14432/j.macvetrev.2015.06.048
ER  - 

@article{
author = "Dzadzovski, Igor and Celeska, Irena and Ulchar, Igor and Janevski, Aleksandar and Kirovski, Danijela",
year = "2015",
abstract = "Chios is a breed of sheep selected for milk production, with metabolic features typical for a dairy sheep breed. The energy requirements of pregnant sheep is increase in the last weeks of gestation. Metabolic imbalance in the late pregnancy in sheep, usually cause a metabolic disorder known as pregnancy toxemia. Additionally, a pregnant sheep exposed to low environmental temperatures has increased energy demands, due to its adaptation to undesirable environmental conditions. The aim of this study was to compare the metabolic profile of Chios sheep exposed to different environmental conditions. Two groups of ewes were instigated. First group included 8 pregnant ewes with clinical signs of pregnancy toxemia exposed to cold stress during the winter season. The second group included 8 non-pregnant, clinically healthy ewes, that were examined during the non-breeding period, in the spring season. Blood samples were taken and serum concentrations of glucose, beta-hydroxybutirate (BHBA), total protein, albumin, urea, creatinine, triglyceride and cholesterol, as well as activity of AST and ALP were determined. Pregnant ewes exposed to cold stress had significantly lower levels of glucose and total protein, and significantly higher levels of BHBA, albumin and AST in the serum compared to non-pregnant ewes that were in optimal environmental conditions. There was no significant difference between the serum levels of urea, creatinine, cholesterol, triglycerides and ALP among the groups. In conclusion, low environmental temperature and poor feeding during the winter season caused metabolic distress in pregnant ewes during the early winter season.",
publisher = "Univ Sv Kiril & Metodij Skopje, Fak Veterinarna Medicina, Skopje",
journal = "Macedonian Veterinary Review",
title = "Influence of the season on the metabolic profile in chios sheep",
volume = "38",
number = "2",
pages = "183-188",
doi = "10.14432/j.macvetrev.2015.06.048"
}

Dzadzovski, I., Celeska, I., Ulchar, I., Janevski, A.,& Kirovski, D.. (2015). Influence of the season on the metabolic profile in chios sheep. in Macedonian Veterinary Review
Univ Sv Kiril & Metodij Skopje, Fak Veterinarna Medicina, Skopje., 38(2), 183-188.
https://doi.org/10.14432/j.macvetrev.2015.06.048

Dzadzovski I, Celeska I, Ulchar I, Janevski A, Kirovski D. Influence of the season on the metabolic profile in chios sheep. in Macedonian Veterinary Review. 2015;38(2):183-188.
doi:10.14432/j.macvetrev.2015.06.048 .

Dzadzovski, Igor, Celeska, Irena, Ulchar, Igor, Janevski, Aleksandar, Kirovski, Danijela, "Influence of the season on the metabolic profile in chios sheep" in Macedonian Veterinary Review, 38, no. 2 (2015):183-188,
https://doi.org/10.14432/j.macvetrev.2015.06.048 . .

TY  - JOUR
AU  - Celeska, Irena
AU  - Janevski, Aleksandar
AU  - Dzadzovski, Igor
AU  - Ulchar, Igor
AU  - Kirovski, Danijela
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1250
AB  - The peripartal period in Holstein dairy cows is critical, due to the transition from pregnancy to lactation. We have studied the dynamics of biochemical parameters from day 5 before to day 60 after calving. The study included 10 multiparous Holstein cows, examined at days -5, 5, 10, 30 and 60 relative to calving. Blood samples were taken from vena jugularis. Analyzed biochemical parameters were glucose, triglycerides, total cholesterol, total bilirubin, albumin, total protein, urea, NEFA and BHBA. Milk production and body condition score were also estimated. Obtained results showed that cows were exposed to mild to marked metabolic distress. Energy status was changed due to increased values of NEFA and BHBA and decreased value of glucose after calving. Protein concentrations were increased at day 10 after calving, despite the decrease of the level of albumin. Urea concentrations before and after calving were within physiological range indicating an optimal protein diet. Increased values of total bilirubin at day 5 after calving indicated liver increased activity. Lipid status presented by triglycerides and total cholesterol revealed no differences in blood concentrations. Milk production was highest at day 30 after calving. BCS were highest in dry cows, thereafter they declined and recovered at day 60 after calving. In conclusion, biochemical parameters can be used as relevant indicators of metabolic distress in cows around calving with milk and BCS recording as aside parameters. Changes in some biochemical parameters indicate liver increased activity and metabolic stress, that could lead to decreased milk production, impaired reproductive performance and, finally, to illness.
PB  - Univ Sv Kiril & Metodij Skopje, Fak Veterinarna Medicina, Skopje
T2  - Macedonian Veterinary Review
T1  - The dynamics of biochemical parameters in blood of clinically healthy holstein cows from day 5 before to day 60 after calving
VL  - 38
IS  - 2
SP  - 189
EP  - 193
DO  - 10.14432/j.macvetrev.2015.07.049
ER  - 

@article{
author = "Celeska, Irena and Janevski, Aleksandar and Dzadzovski, Igor and Ulchar, Igor and Kirovski, Danijela",
year = "2015",
abstract = "The peripartal period in Holstein dairy cows is critical, due to the transition from pregnancy to lactation. We have studied the dynamics of biochemical parameters from day 5 before to day 60 after calving. The study included 10 multiparous Holstein cows, examined at days -5, 5, 10, 30 and 60 relative to calving. Blood samples were taken from vena jugularis. Analyzed biochemical parameters were glucose, triglycerides, total cholesterol, total bilirubin, albumin, total protein, urea, NEFA and BHBA. Milk production and body condition score were also estimated. Obtained results showed that cows were exposed to mild to marked metabolic distress. Energy status was changed due to increased values of NEFA and BHBA and decreased value of glucose after calving. Protein concentrations were increased at day 10 after calving, despite the decrease of the level of albumin. Urea concentrations before and after calving were within physiological range indicating an optimal protein diet. Increased values of total bilirubin at day 5 after calving indicated liver increased activity. Lipid status presented by triglycerides and total cholesterol revealed no differences in blood concentrations. Milk production was highest at day 30 after calving. BCS were highest in dry cows, thereafter they declined and recovered at day 60 after calving. In conclusion, biochemical parameters can be used as relevant indicators of metabolic distress in cows around calving with milk and BCS recording as aside parameters. Changes in some biochemical parameters indicate liver increased activity and metabolic stress, that could lead to decreased milk production, impaired reproductive performance and, finally, to illness.",
publisher = "Univ Sv Kiril & Metodij Skopje, Fak Veterinarna Medicina, Skopje",
journal = "Macedonian Veterinary Review",
title = "The dynamics of biochemical parameters in blood of clinically healthy holstein cows from day 5 before to day 60 after calving",
volume = "38",
number = "2",
pages = "189-193",
doi = "10.14432/j.macvetrev.2015.07.049"
}

Celeska, I., Janevski, A., Dzadzovski, I., Ulchar, I.,& Kirovski, D.. (2015). The dynamics of biochemical parameters in blood of clinically healthy holstein cows from day 5 before to day 60 after calving. in Macedonian Veterinary Review
Univ Sv Kiril & Metodij Skopje, Fak Veterinarna Medicina, Skopje., 38(2), 189-193.
https://doi.org/10.14432/j.macvetrev.2015.07.049

Celeska I, Janevski A, Dzadzovski I, Ulchar I, Kirovski D. The dynamics of biochemical parameters in blood of clinically healthy holstein cows from day 5 before to day 60 after calving. in Macedonian Veterinary Review. 2015;38(2):189-193.
doi:10.14432/j.macvetrev.2015.07.049 .

Celeska, Irena, Janevski, Aleksandar, Dzadzovski, Igor, Ulchar, Igor, Kirovski, Danijela, "The dynamics of biochemical parameters in blood of clinically healthy holstein cows from day 5 before to day 60 after calving" in Macedonian Veterinary Review, 38, no. 2 (2015):189-193,
https://doi.org/10.14432/j.macvetrev.2015.07.049 . .

TY  - JOUR
AU  - Šamanc, Horea
AU  - Kirovski, Danijela
AU  - Lakić, Nada
AU  - Celeska, Irena
AU  - Bojkovic-Kovacević, Slavica
AU  - Sladojević, Željko
AU  - Ivanov, Ivan
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1105
AB  - The aim of this study was to compare the concentrations of blood variables obtained simultaneously from the jugular and mammary veins of dairy cows. Eighty Holstein cows were divided into four equal groups: dry, low- (LY), medium- (MY) and high-yielding (HY). Blood insulin, glucose, non-esterified fatty acid (NEFA), beta-hydroxybutyrate (BHBA) and urea concentrations were measured. The jugular and mammary vein (J/M) ratio between concentrations of each variable was calculated. Differences between the groups of cows in concentrations of variables in the jugular vein were not in accordance with those obtained for the mammary vein. J/M values for insulin and glucose concentrations were above 1.0 in all groups of cows. The ratios for NEFA and BHBA concentrations were under or equal to 1.0 in dry and LY cows but above 1.0 in the MY and HY groups, indicating that in MY and HY cows those metabolites are apparently utilised by the mammary gland. J/M values for urea were above 1.0 in dry and LY cows but less than 1.0 in groups MY and HY, indicating that in the latter case urea is apparently released by the mammary gland. In conclusion, J/M for NEFA, BHBA and urea may be useful for estimation of the critical point when the mammary gland receives insufficient energy precursors for its current activity.
PB  - Akademiai Kiado Rt, Budapest
T2  - Acta Veterinaria Hungarica
T1  - A comparison of the concentrations of energy-balance-related variables in jugular and mammary vein blood of dairy cows with different milk yield
VL  - 62
IS  - 1
SP  - 52
EP  - 63
DO  - 10.1556/AVet.2013.055
ER  - 

@article{
author = "Šamanc, Horea and Kirovski, Danijela and Lakić, Nada and Celeska, Irena and Bojkovic-Kovacević, Slavica and Sladojević, Željko and Ivanov, Ivan",
year = "2014",
abstract = "The aim of this study was to compare the concentrations of blood variables obtained simultaneously from the jugular and mammary veins of dairy cows. Eighty Holstein cows were divided into four equal groups: dry, low- (LY), medium- (MY) and high-yielding (HY). Blood insulin, glucose, non-esterified fatty acid (NEFA), beta-hydroxybutyrate (BHBA) and urea concentrations were measured. The jugular and mammary vein (J/M) ratio between concentrations of each variable was calculated. Differences between the groups of cows in concentrations of variables in the jugular vein were not in accordance with those obtained for the mammary vein. J/M values for insulin and glucose concentrations were above 1.0 in all groups of cows. The ratios for NEFA and BHBA concentrations were under or equal to 1.0 in dry and LY cows but above 1.0 in the MY and HY groups, indicating that in MY and HY cows those metabolites are apparently utilised by the mammary gland. J/M values for urea were above 1.0 in dry and LY cows but less than 1.0 in groups MY and HY, indicating that in the latter case urea is apparently released by the mammary gland. In conclusion, J/M for NEFA, BHBA and urea may be useful for estimation of the critical point when the mammary gland receives insufficient energy precursors for its current activity.",
publisher = "Akademiai Kiado Rt, Budapest",
journal = "Acta Veterinaria Hungarica",
title = "A comparison of the concentrations of energy-balance-related variables in jugular and mammary vein blood of dairy cows with different milk yield",
volume = "62",
number = "1",
pages = "52-63",
doi = "10.1556/AVet.2013.055"
}

Šamanc, H., Kirovski, D., Lakić, N., Celeska, I., Bojkovic-Kovacević, S., Sladojević, Ž.,& Ivanov, I.. (2014). A comparison of the concentrations of energy-balance-related variables in jugular and mammary vein blood of dairy cows with different milk yield. in Acta Veterinaria Hungarica
Akademiai Kiado Rt, Budapest., 62(1), 52-63.
https://doi.org/10.1556/AVet.2013.055

Šamanc H, Kirovski D, Lakić N, Celeska I, Bojkovic-Kovacević S, Sladojević Ž, Ivanov I. A comparison of the concentrations of energy-balance-related variables in jugular and mammary vein blood of dairy cows with different milk yield. in Acta Veterinaria Hungarica. 2014;62(1):52-63.
doi:10.1556/AVet.2013.055 .

Šamanc, Horea, Kirovski, Danijela, Lakić, Nada, Celeska, Irena, Bojkovic-Kovacević, Slavica, Sladojević, Željko, Ivanov, Ivan, "A comparison of the concentrations of energy-balance-related variables in jugular and mammary vein blood of dairy cows with different milk yield" in Acta Veterinaria Hungarica, 62, no. 1 (2014):52-63,
https://doi.org/10.1556/AVet.2013.055 . .