Primorac, Marija

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  • Primorac, Marija (1)
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Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts

Arsić, Ivana; Žugić, Ana R.; Tadić, Vanja M.; Tasic-Kostov, Marija; Mišić, Dušan; Primorac, Marija; Runjaic-Antić, Dusanka

(MDPI, Basel, 2012)

TY  - JOUR
AU  - Arsić, Ivana
AU  - Žugić, Ana R.
AU  - Tadić, Vanja M.
AU  - Tasic-Kostov, Marija
AU  - Mišić, Dušan
AU  - Primorac, Marija
AU  - Runjaic-Antić, Dusanka
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/890
AB  - Oleum Hyperici, the oil extract of St. Johns Wort (SJW), is one of the oldest folk remedies, traditionally used in the topical treatment of wounds, bruises, ulcers, cuts, burns, hemorrhoids and also as an antiseptic. Considering the advantageous characteristics of emulsion applications, in the present study we have formulated three O/W creams containing 15% (w/v) of SJW oil extract as an active ingredient. The aim was to estimate dermatological application of the prepared creams for the abovementioned indications. The extracts were prepared according to the prescriptions from traditional medicine, however with different vegetable oils used as an extractant, namely: Olive, palm and sunflower oil. The investigated O/W creams demonstrated significant antiinflammatory effects in an in vivo double-blind randomized study, using a sodium lauryl sulphate test. Both skin parameters assessed in the study (electrical capacitance and erythema index), were restored to the baseline value after a seven-day treatment with the tested creams. Almost all investigated SJW oil extracts and corresponding creams displayed the same antimicrobial activity against the most of the investigated microorganisms with obtained minimal inhibitory concentrations values of 1,280 mu g/mL, 2,560 mu g/mL or >2,560 mu g/mL.
PB  - MDPI, Basel
T2  - Molecules
T1  - Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts
VL  - 17
IS  - 1
SP  - 275
EP  - 294
DO  - 10.3390/molecules17010275
ER  - 
@article{
author = "Arsić, Ivana and Žugić, Ana R. and Tadić, Vanja M. and Tasic-Kostov, Marija and Mišić, Dušan and Primorac, Marija and Runjaic-Antić, Dusanka",
year = "2012",
abstract = "Oleum Hyperici, the oil extract of St. Johns Wort (SJW), is one of the oldest folk remedies, traditionally used in the topical treatment of wounds, bruises, ulcers, cuts, burns, hemorrhoids and also as an antiseptic. Considering the advantageous characteristics of emulsion applications, in the present study we have formulated three O/W creams containing 15% (w/v) of SJW oil extract as an active ingredient. The aim was to estimate dermatological application of the prepared creams for the abovementioned indications. The extracts were prepared according to the prescriptions from traditional medicine, however with different vegetable oils used as an extractant, namely: Olive, palm and sunflower oil. The investigated O/W creams demonstrated significant antiinflammatory effects in an in vivo double-blind randomized study, using a sodium lauryl sulphate test. Both skin parameters assessed in the study (electrical capacitance and erythema index), were restored to the baseline value after a seven-day treatment with the tested creams. Almost all investigated SJW oil extracts and corresponding creams displayed the same antimicrobial activity against the most of the investigated microorganisms with obtained minimal inhibitory concentrations values of 1,280 mu g/mL, 2,560 mu g/mL or >2,560 mu g/mL.",
publisher = "MDPI, Basel",
journal = "Molecules",
title = "Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts",
volume = "17",
number = "1",
pages = "275-294",
doi = "10.3390/molecules17010275"
}
Arsić, I., Žugić, A. R., Tadić, V. M., Tasic-Kostov, M., Mišić, D., Primorac, M.,& Runjaic-Antić, D.. (2012). Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts. in Molecules
MDPI, Basel., 17(1), 275-294.
https://doi.org/10.3390/molecules17010275
Arsić I, Žugić AR, Tadić VM, Tasic-Kostov M, Mišić D, Primorac M, Runjaic-Antić D. Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts. in Molecules. 2012;17(1):275-294.
doi:10.3390/molecules17010275 .
Arsić, Ivana, Žugić, Ana R., Tadić, Vanja M., Tasic-Kostov, Marija, Mišić, Dušan, Primorac, Marija, Runjaic-Antić, Dusanka, "Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts" in Molecules, 17, no. 1 (2012):275-294,
https://doi.org/10.3390/molecules17010275 . .
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