TY  - JOUR
AU  - Cenić-Milošević, Desanka
AU  - Tambur, Zoran
AU  - Ivančajić, S.
AU  - Bokonjić, Dubravko
AU  - Čuković, Anika
AU  - Stanojković, Tatjana
AU  - Grozdanić, Nadja
AU  - Kulišić, Zoran
AU  - Juranić, Zorica
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/965
AB  - The use of medicinal plants is becoming increasingly appreciated in suppressing cancer growth and cancer prevention. In this study the antiproliferative effects of the water extracts of previously obtained ethanolic dry extracts of three different medicinal plants (Camellia sinensis, Frangula alnus from two different places and Rosmarinus officinalis) using cell lines derived from human cervix adenocarcinoma (Hela cells) were investigated. The extract of Camellia sinensis exhibited significant cytotoxic effect against Hela cells (IC50 40.88 μg/ml). Screening in Hela cells revealed a moderate cytotoxic effect (IC50 80.26μg/ml) of the extract of Rosmarinus officinalis, a mild cytotoxic effect (IC50 148.05 μg/ml) of the extract of Frangula alnus (originating in Bosnia), and the extract of Frangula alnus (originating in Serbia) did not show active cytotoxicity (IC50 > 200 μg/ml). The best antiproliferative properties are those of Camellia sinensis, followed by Rosmarinus officinalis, and the least effective was Frangula alnus. As regards geographic origin, the Frangula alnus from Bosnia possessed better antiproliferative effects than Frangula alnus from Serbia.
PB  - Srpsko biološko društvo, Beograd, i dr.
T2  - Archives of Biological Sciences
T1  - Antiproliferative effects of Camellia sinensis, Frangula alnus and Rosmarinus officinalis
VL  - 65
IS  - 3
SP  - 885
EP  - 891
DO  - 10.2298/ABS1303885M
ER  - 

@article{
author = "Cenić-Milošević, Desanka and Tambur, Zoran and Ivančajić, S. and Bokonjić, Dubravko and Čuković, Anika and Stanojković, Tatjana and Grozdanić, Nadja and Kulišić, Zoran and Juranić, Zorica",
year = "2013",
abstract = "The use of medicinal plants is becoming increasingly appreciated in suppressing cancer growth and cancer prevention. In this study the antiproliferative effects of the water extracts of previously obtained ethanolic dry extracts of three different medicinal plants (Camellia sinensis, Frangula alnus from two different places and Rosmarinus officinalis) using cell lines derived from human cervix adenocarcinoma (Hela cells) were investigated. The extract of Camellia sinensis exhibited significant cytotoxic effect against Hela cells (IC50 40.88 μg/ml). Screening in Hela cells revealed a moderate cytotoxic effect (IC50 80.26μg/ml) of the extract of Rosmarinus officinalis, a mild cytotoxic effect (IC50 148.05 μg/ml) of the extract of Frangula alnus (originating in Bosnia), and the extract of Frangula alnus (originating in Serbia) did not show active cytotoxicity (IC50 > 200 μg/ml). The best antiproliferative properties are those of Camellia sinensis, followed by Rosmarinus officinalis, and the least effective was Frangula alnus. As regards geographic origin, the Frangula alnus from Bosnia possessed better antiproliferative effects than Frangula alnus from Serbia.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "Antiproliferative effects of Camellia sinensis, Frangula alnus and Rosmarinus officinalis",
volume = "65",
number = "3",
pages = "885-891",
doi = "10.2298/ABS1303885M"
}

Cenić-Milošević, D., Tambur, Z., Ivančajić, S., Bokonjić, D., Čuković, A., Stanojković, T., Grozdanić, N., Kulišić, Z.,& Juranić, Z.. (2013). Antiproliferative effects of Camellia sinensis, Frangula alnus and Rosmarinus officinalis. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 65(3), 885-891.
https://doi.org/10.2298/ABS1303885M

Cenić-Milošević D, Tambur Z, Ivančajić S, Bokonjić D, Čuković A, Stanojković T, Grozdanić N, Kulišić Z, Juranić Z. Antiproliferative effects of Camellia sinensis, Frangula alnus and Rosmarinus officinalis. in Archives of Biological Sciences. 2013;65(3):885-891.
doi:10.2298/ABS1303885M .

Cenić-Milošević, Desanka, Tambur, Zoran, Ivančajić, S., Bokonjić, Dubravko, Čuković, Anika, Stanojković, Tatjana, Grozdanić, Nadja, Kulišić, Zoran, Juranić, Zorica, "Antiproliferative effects of Camellia sinensis, Frangula alnus and Rosmarinus officinalis" in Archives of Biological Sciences, 65, no. 3 (2013):885-891,
https://doi.org/10.2298/ABS1303885M . .