TY  - JOUR
AU  - Mitrović, Marko Jumake
AU  - Tatalović, Nikola R.
AU  - Nikolic-Kokić, Aleksandra L.
AU  - Ciraj-Bjelac, Olivera F.
AU  - Krstić, Nikola
AU  - Orescanin-Dusić, Zorana S.
AU  - Krstić, Dragana Z.
AU  - Jovanović, Zoran M.
AU  - Blagojević, Duško P.
AU  - Lazarević Macanović, Mirjana
PY  - 2018
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1574
AB  - In recent years, computed tomography (CT) has become very common in veterinary medicine. It is well known that testicles are organs with high radiosensitivity and their function can be impaired even after exposure to low radiation doses. In this work, we calculated the absorbed radiation doses after CT was performed with different voltage/current levels and correlated it with the activity of antioxidant enzymes in rabbit testicles. Two hours after CT, the activities of catalase (CAT) and glutathione peroxidase (GSH-Px) were increased in the testicles of animals that received an absorbed dose of 29.2 mGy. The same changes, along with elevated glutathione reductase (GR) activity, were observed after 7 days in animals that received the highest absorbed dose (46.3 mGy). It would appear that absorbed doses above 27.8 mGy provoked the antioxidant reaction but the time scale of the reaction was dose-dependent. Examination of the obtained results revealed that the main denominator of CT influence was a higher current. Our results suggest that CT influences the antioxidant status in rabbit testicles. The changes in antioxidant enzyme activities were dose- and time-dependent and influenced by the applied current.
PB  - Srpsko biološko društvo, Beograd
T2  - Archives of Biological Sciences
T1  - Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles
VL  - 70
IS  - 4
SP  - 675
EP  - 680
DO  - 10.2298/ABS180413029M
ER  - 

@article{
author = "Mitrović, Marko Jumake and Tatalović, Nikola R. and Nikolic-Kokić, Aleksandra L. and Ciraj-Bjelac, Olivera F. and Krstić, Nikola and Orescanin-Dusić, Zorana S. and Krstić, Dragana Z. and Jovanović, Zoran M. and Blagojević, Duško P. and Lazarević Macanović, Mirjana",
year = "2018",
abstract = "In recent years, computed tomography (CT) has become very common in veterinary medicine. It is well known that testicles are organs with high radiosensitivity and their function can be impaired even after exposure to low radiation doses. In this work, we calculated the absorbed radiation doses after CT was performed with different voltage/current levels and correlated it with the activity of antioxidant enzymes in rabbit testicles. Two hours after CT, the activities of catalase (CAT) and glutathione peroxidase (GSH-Px) were increased in the testicles of animals that received an absorbed dose of 29.2 mGy. The same changes, along with elevated glutathione reductase (GR) activity, were observed after 7 days in animals that received the highest absorbed dose (46.3 mGy). It would appear that absorbed doses above 27.8 mGy provoked the antioxidant reaction but the time scale of the reaction was dose-dependent. Examination of the obtained results revealed that the main denominator of CT influence was a higher current. Our results suggest that CT influences the antioxidant status in rabbit testicles. The changes in antioxidant enzyme activities were dose- and time-dependent and influenced by the applied current.",
publisher = "Srpsko biološko društvo, Beograd",
journal = "Archives of Biological Sciences",
title = "Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles",
volume = "70",
number = "4",
pages = "675-680",
doi = "10.2298/ABS180413029M"
}

Mitrović, M. J., Tatalović, N. R., Nikolic-Kokić, A. L., Ciraj-Bjelac, O. F., Krstić, N., Orescanin-Dusić, Z. S., Krstić, D. Z., Jovanović, Z. M., Blagojević, D. P.,& Lazarević Macanović, M.. (2018). Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd., 70(4), 675-680.
https://doi.org/10.2298/ABS180413029M

Mitrović MJ, Tatalović NR, Nikolic-Kokić AL, Ciraj-Bjelac OF, Krstić N, Orescanin-Dusić ZS, Krstić DZ, Jovanović ZM, Blagojević DP, Lazarević Macanović M. Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles. in Archives of Biological Sciences. 2018;70(4):675-680.
doi:10.2298/ABS180413029M .

Mitrović, Marko Jumake, Tatalović, Nikola R., Nikolic-Kokić, Aleksandra L., Ciraj-Bjelac, Olivera F., Krstić, Nikola, Orescanin-Dusić, Zorana S., Krstić, Dragana Z., Jovanović, Zoran M., Blagojević, Duško P., Lazarević Macanović, Mirjana, "Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles" in Archives of Biological Sciences, 70, no. 4 (2018):675-680,
https://doi.org/10.2298/ABS180413029M . .

TY  - JOUR
AU  - Mitrović, Marko Jumake
AU  - Ciraj-Bjelac, Olivera F.
AU  - Orescanin-Dusić, Zorana S.
AU  - Blagojević, Duško P.
AU  - Nikolic-Kokić, Aleksandra L.
AU  - Tatalović, Nikola R.
AU  - Krstić, Nikola
AU  - Lazarević Macanović, Mirjana
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1447
AB  - The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.
PB  - Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd
T2  - Nuclear Technology and Radiation Protection
T1  - Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes
VL  - 32
IS  - 4
SP  - 342
EP  - 349
DO  - 10.2298/NTRP1704342M
ER  - 

@article{
author = "Mitrović, Marko Jumake and Ciraj-Bjelac, Olivera F. and Orescanin-Dusić, Zorana S. and Blagojević, Duško P. and Nikolic-Kokić, Aleksandra L. and Tatalović, Nikola R. and Krstić, Nikola and Lazarević Macanović, Mirjana",
year = "2017",
abstract = "The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.",
publisher = "Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd",
journal = "Nuclear Technology and Radiation Protection",
title = "Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes",
volume = "32",
number = "4",
pages = "342-349",
doi = "10.2298/NTRP1704342M"
}

Mitrović, M. J., Ciraj-Bjelac, O. F., Orescanin-Dusić, Z. S., Blagojević, D. P., Nikolic-Kokić, A. L., Tatalović, N. R., Krstić, N.,& Lazarević Macanović, M.. (2017). Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes. in Nuclear Technology and Radiation Protection
Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd., 32(4), 342-349.
https://doi.org/10.2298/NTRP1704342M

Mitrović MJ, Ciraj-Bjelac OF, Orescanin-Dusić ZS, Blagojević DP, Nikolic-Kokić AL, Tatalović NR, Krstić N, Lazarević Macanović M. Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes. in Nuclear Technology and Radiation Protection. 2017;32(4):342-349.
doi:10.2298/NTRP1704342M .

Mitrović, Marko Jumake, Ciraj-Bjelac, Olivera F., Orescanin-Dusić, Zorana S., Blagojević, Duško P., Nikolic-Kokić, Aleksandra L., Tatalović, Nikola R., Krstić, Nikola, Lazarević Macanović, Mirjana, "Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes" in Nuclear Technology and Radiation Protection, 32, no. 4 (2017):342-349,
https://doi.org/10.2298/NTRP1704342M . .