Radanović, Oliver

Link to this page

Authority KeyName Variants
orcid::0000-0002-5275-5582
  • Radanović, Oliver (22)
Projects

Author's Bibliography

Dezinfekciono delovanje uv lampi

Zdravković, Nemanja; Radanović, Oliver; Zdravković, Zorica; Grujović, Teodora; Marjanović, Đorđe; Medić, Dragana; Cvetković, Ružica; Ninković, Milan

(Beograd : Srpsko veterinarsko društvo, 2023)

TY  - CONF
AU  - Zdravković, Nemanja
AU  - Radanović, Oliver
AU  - Zdravković, Zorica
AU  - Grujović, Teodora
AU  - Marjanović, Đorđe
AU  - Medić, Dragana
AU  - Cvetković, Ružica
AU  - Ninković, Milan
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3123
AB  - Priča o prevenciji i kontroli zaraznih bolesti ostaje otvorena jer se niz patogenih bakterija iznova pojavljuje kao izazivač infekcija. Da bi se taj problem prevazišao, antibiotici su bili dominantni tokom prethodne ere. Rezistencija kao fenomen kojim se patogeni mikroorganizmi opiru dejstvu lekove je postavo izuzetno raširen u svetu. Više naučnih pravaca se razvija u svrhu prevazilaženja ovog problema, pa je tako fotodinamička inaktivacija definisana u platformu za otkrivanje i razvoj antimikrobnih sredstava. Koncept fotodinamičke inaktivacije je prilično jednostavan i zahteva izlaganje mikroba energijom svetla koja uzrokuje pobuđivanje molekula, što rezultira proizvodnjom singlet kiseonika ili drugim reaktivnim kiseoničkim vrstama koje reaguju sa intracelularnim komponentama, a posledi«no dovode do ćelijske inaktivacije. To je oblast sve većeg interesovanja, kao i istraživanja u smerovima: (1) da se identifikuju fotohemijski i fotofizi«ki mehanizmi uključeni u inaktivaciju, (2) da razviju moćni i klinički kompatibilni fotosenzibilizatori, (3) da se razume kako na fotoinaktivaciju utiču ključni mikrobni fenotip elementi (rezistencija na više lekova i efluks, virulencija i determinante patogeneze, biofilmovi), (4) da se istraže nove platforme za isporuku inspirisane trenutnim trendovima u farmakologiji i nanotehnologijama i (5) za identifikaciju fotoinaktivacije primene izvan kliničkog okruženja kao što je životna sredina tj. dezinfekciona sredstva.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 34 Savetovanje Dezinfekcija, dezinsekcija i deratizacija - Jedan svet jedno zdravlje, Vrnjačka Banja, 8 - 11. jun 2023
T1  - Dezinfekciono delovanje uv lampi
SP  - 32
EP  - 37
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3123
ER  - 
@conference{
author = "Zdravković, Nemanja and Radanović, Oliver and Zdravković, Zorica and Grujović, Teodora and Marjanović, Đorđe and Medić, Dragana and Cvetković, Ružica and Ninković, Milan",
year = "2023",
abstract = "Priča o prevenciji i kontroli zaraznih bolesti ostaje otvorena jer se niz patogenih bakterija iznova pojavljuje kao izazivač infekcija. Da bi se taj problem prevazišao, antibiotici su bili dominantni tokom prethodne ere. Rezistencija kao fenomen kojim se patogeni mikroorganizmi opiru dejstvu lekove je postavo izuzetno raširen u svetu. Više naučnih pravaca se razvija u svrhu prevazilaženja ovog problema, pa je tako fotodinamička inaktivacija definisana u platformu za otkrivanje i razvoj antimikrobnih sredstava. Koncept fotodinamičke inaktivacije je prilično jednostavan i zahteva izlaganje mikroba energijom svetla koja uzrokuje pobuđivanje molekula, što rezultira proizvodnjom singlet kiseonika ili drugim reaktivnim kiseoničkim vrstama koje reaguju sa intracelularnim komponentama, a posledi«no dovode do ćelijske inaktivacije. To je oblast sve većeg interesovanja, kao i istraživanja u smerovima: (1) da se identifikuju fotohemijski i fotofizi«ki mehanizmi uključeni u inaktivaciju, (2) da razviju moćni i klinički kompatibilni fotosenzibilizatori, (3) da se razume kako na fotoinaktivaciju utiču ključni mikrobni fenotip elementi (rezistencija na više lekova i efluks, virulencija i determinante patogeneze, biofilmovi), (4) da se istraže nove platforme za isporuku inspirisane trenutnim trendovima u farmakologiji i nanotehnologijama i (5) za identifikaciju fotoinaktivacije primene izvan kliničkog okruženja kao što je životna sredina tj. dezinfekciona sredstva.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "34 Savetovanje Dezinfekcija, dezinsekcija i deratizacija - Jedan svet jedno zdravlje, Vrnjačka Banja, 8 - 11. jun 2023",
title = "Dezinfekciono delovanje uv lampi",
pages = "32-37",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3123"
}
Zdravković, N., Radanović, O., Zdravković, Z., Grujović, T., Marjanović, Đ., Medić, D., Cvetković, R.,& Ninković, M.. (2023). Dezinfekciono delovanje uv lampi. in 34 Savetovanje Dezinfekcija, dezinsekcija i deratizacija - Jedan svet jedno zdravlje, Vrnjačka Banja, 8 - 11. jun 2023
Beograd : Srpsko veterinarsko društvo., 32-37.
https://hdl.handle.net/21.15107/rcub_veterinar_3123
Zdravković N, Radanović O, Zdravković Z, Grujović T, Marjanović Đ, Medić D, Cvetković R, Ninković M. Dezinfekciono delovanje uv lampi. in 34 Savetovanje Dezinfekcija, dezinsekcija i deratizacija - Jedan svet jedno zdravlje, Vrnjačka Banja, 8 - 11. jun 2023. 2023;:32-37.
https://hdl.handle.net/21.15107/rcub_veterinar_3123 .
Zdravković, Nemanja, Radanović, Oliver, Zdravković, Zorica, Grujović, Teodora, Marjanović, Đorđe, Medić, Dragana, Cvetković, Ružica, Ninković, Milan, "Dezinfekciono delovanje uv lampi" in 34 Savetovanje Dezinfekcija, dezinsekcija i deratizacija - Jedan svet jedno zdravlje, Vrnjačka Banja, 8 - 11. jun 2023 (2023):32-37,
https://hdl.handle.net/21.15107/rcub_veterinar_3123 .

Trematode kod svinja

Pavlović, Ivan; Radanović, Oliver; Zdravković, Nemanja; Savić, Božidar; Vasić, Ana; Bojkovski, Jovan; Dobrosavljević, Ivan; Stokić-Nikolić, Slavonka; Tasić, Aleksandra; Pavlović, Marija; Relić, Renata

(Požarevac : Sitograf RM, 2023)

TY  - CONF
AU  - Pavlović, Ivan
AU  - Radanović, Oliver
AU  - Zdravković, Nemanja
AU  - Savić, Božidar
AU  - Vasić, Ana
AU  - Bojkovski, Jovan
AU  - Dobrosavljević, Ivan
AU  - Stokić-Nikolić, Slavonka
AU  - Tasić, Aleksandra
AU  - Pavlović, Marija
AU  - Relić, Renata
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3364
AB  - Klasa Trematoda, u narodu poznatija kao metlji, obuhvata parazite čije telo nije
segmentisano na člančiće i poseduju organe za pričršćivanja u vidu jakih muskuloznih pijavki.
Kod svinja parazitira mali broj trematoda od kojih je većina u adultnom obliku a neke se nalaze
incistirane u larvarnom stadijumu najčešće u mišićima svinja. U Evropi je prisutan mali broj
trematoda ali su one zato u Aziji u velikom broju prisutne u patologiji svinja i ljudi. Ovde će mo
dati prikaz najznačajnih zoonotske trematoda svinja: Alaria alata, Fasciola hepatica, Dicrocelium
dendriticum, Fasciolopsis buski, Clonorchis sinensis i Opisthorchis felineus.
PB  - Požarevac : Sitograf RM
C3  - 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 8 - 9. jun 2023
T1  - Trematode kod svinja
SP  - 115
EP  - 121
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3364
ER  - 
@conference{
author = "Pavlović, Ivan and Radanović, Oliver and Zdravković, Nemanja and Savić, Božidar and Vasić, Ana and Bojkovski, Jovan and Dobrosavljević, Ivan and Stokić-Nikolić, Slavonka and Tasić, Aleksandra and Pavlović, Marija and Relić, Renata",
year = "2023",
abstract = "Klasa Trematoda, u narodu poznatija kao metlji, obuhvata parazite čije telo nije
segmentisano na člančiće i poseduju organe za pričršćivanja u vidu jakih muskuloznih pijavki.
Kod svinja parazitira mali broj trematoda od kojih je većina u adultnom obliku a neke se nalaze
incistirane u larvarnom stadijumu najčešće u mišićima svinja. U Evropi je prisutan mali broj
trematoda ali su one zato u Aziji u velikom broju prisutne u patologiji svinja i ljudi. Ovde će mo
dati prikaz najznačajnih zoonotske trematoda svinja: Alaria alata, Fasciola hepatica, Dicrocelium
dendriticum, Fasciolopsis buski, Clonorchis sinensis i Opisthorchis felineus.",
publisher = "Požarevac : Sitograf RM",
journal = "20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 8 - 9. jun 2023",
title = "Trematode kod svinja",
pages = "115-121",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3364"
}
Pavlović, I., Radanović, O., Zdravković, N., Savić, B., Vasić, A., Bojkovski, J., Dobrosavljević, I., Stokić-Nikolić, S., Tasić, A., Pavlović, M.,& Relić, R.. (2023). Trematode kod svinja. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 8 - 9. jun 2023
Požarevac : Sitograf RM., 115-121.
https://hdl.handle.net/21.15107/rcub_veterinar_3364
Pavlović I, Radanović O, Zdravković N, Savić B, Vasić A, Bojkovski J, Dobrosavljević I, Stokić-Nikolić S, Tasić A, Pavlović M, Relić R. Trematode kod svinja. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 8 - 9. jun 2023. 2023;:115-121.
https://hdl.handle.net/21.15107/rcub_veterinar_3364 .
Pavlović, Ivan, Radanović, Oliver, Zdravković, Nemanja, Savić, Božidar, Vasić, Ana, Bojkovski, Jovan, Dobrosavljević, Ivan, Stokić-Nikolić, Slavonka, Tasić, Aleksandra, Pavlović, Marija, Relić, Renata, "Trematode kod svinja" in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 8 - 9. jun 2023 (2023):115-121,
https://hdl.handle.net/21.15107/rcub_veterinar_3364 .

Higijena muže kao faktor prevencije bolesti mlečne žlezde

Đorđević, Milutin; Janković, Ljiljana; Drašković, Vladimir; Radanović, Oliver; Zdravković, Nemanja; Teodorović, Radislava

(Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila, 2022)

TY  - CONF
AU  - Đorđević, Milutin
AU  - Janković, Ljiljana
AU  - Drašković, Vladimir
AU  - Radanović, Oliver
AU  - Zdravković, Nemanja
AU  - Teodorović, Radislava
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2796
AB  - Veliki broj muznih krava na malom prostoru, stalni kontakt mlečne žlezde sa
površinama koji su potencijalni nosioci patogena i visoki standardi koji se odnose
na kvalitet i higijensku ispravnost mleka uslovljavaju potrebu da se kontinuirano
primenjuju biosigurnosne mere u farmskim objektima za uzgoj muznih krava.
Količina, kvalitet i higijenska ispravnost mleka kao ključni faktori uspešnosti farmskog
uzgoja krava, pored genetskog potencijala i ishrane, zavise od smeštajnih
uslova, tj. higijenskih mera koje se primenjuju u objektu. Jedna od najvažnijih mera
koje se kontinuirano sprovode je i higijena muže u okviru koje se posebna pažnja
obraća na: higijenu muzača, higijenu vimena pre muže, higijenu papila posle
muže, kao i higijenu opreme za mužu. Higijena muže je jedan od ključnih faktora
za dobar zdravstveni status mlečne žlezde. Velike ekonomske štete uzrokovane
mastitima zahtevaju posebnu pažnju u izradi i sprovođenju planova kontrole mastitisa,
u kojima ključno mesto ima dezinfekcija vimena pre i posle muže. Razvoj
novih dezinficijensa i tehnologija njihove aplikacije, sa dobrim efektom na zdravlje
vimena je jedan od budućih ključnih faktora prevencije bolesti mlečne žlezde.
AB  - The presence of a large number of dairy cows in a small space, the constant
contact of the mammary gland with surfaces that are potential carriers of
pathogens and high standards related to the quality and hygienic correctness of
milk, create a constant need for applying biosecurity measures in farm facilities
for breeding dairy cows. The milk production, quality and hygienic correctness
of the milk, in addition to the genetic potential and nutrition as the key factors in the success of cows breeding, primarily depend on housing conditions, i.e. hygiene
measures applied in the facility. One of the most important measures that
are continuously implemented is milking hygiene procedures, within which special
attention is paid to: hygiene of milkers, hygiene measures before milking, hygiene
measures after milking, as well as hygiene of milking equipment. The milking
hygiene practices is one of the key factors in maintaining the health status of the
mammary gland. The great economic losses that mastitis cause to the dairy industry
requires particular focus in the development and implementation of mastitis
control plans, in which disinfection of udders before and after milking plays a key
role. The development of new disinfectants and their application technologies, with
a good effect on the health of the udder, is one of the future key factors in the
prevention of mammary gland diseases.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022.
T1  - Higijena muže kao faktor prevencije bolesti mlečne žlezde
SP  - 89
EP  - 100
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2796
ER  - 
@conference{
author = "Đorđević, Milutin and Janković, Ljiljana and Drašković, Vladimir and Radanović, Oliver and Zdravković, Nemanja and Teodorović, Radislava",
year = "2022",
abstract = "Veliki broj muznih krava na malom prostoru, stalni kontakt mlečne žlezde sa
površinama koji su potencijalni nosioci patogena i visoki standardi koji se odnose
na kvalitet i higijensku ispravnost mleka uslovljavaju potrebu da se kontinuirano
primenjuju biosigurnosne mere u farmskim objektima za uzgoj muznih krava.
Količina, kvalitet i higijenska ispravnost mleka kao ključni faktori uspešnosti farmskog
uzgoja krava, pored genetskog potencijala i ishrane, zavise od smeštajnih
uslova, tj. higijenskih mera koje se primenjuju u objektu. Jedna od najvažnijih mera
koje se kontinuirano sprovode je i higijena muže u okviru koje se posebna pažnja
obraća na: higijenu muzača, higijenu vimena pre muže, higijenu papila posle
muže, kao i higijenu opreme za mužu. Higijena muže je jedan od ključnih faktora
za dobar zdravstveni status mlečne žlezde. Velike ekonomske štete uzrokovane
mastitima zahtevaju posebnu pažnju u izradi i sprovođenju planova kontrole mastitisa,
u kojima ključno mesto ima dezinfekcija vimena pre i posle muže. Razvoj
novih dezinficijensa i tehnologija njihove aplikacije, sa dobrim efektom na zdravlje
vimena je jedan od budućih ključnih faktora prevencije bolesti mlečne žlezde., The presence of a large number of dairy cows in a small space, the constant
contact of the mammary gland with surfaces that are potential carriers of
pathogens and high standards related to the quality and hygienic correctness of
milk, create a constant need for applying biosecurity measures in farm facilities
for breeding dairy cows. The milk production, quality and hygienic correctness
of the milk, in addition to the genetic potential and nutrition as the key factors in the success of cows breeding, primarily depend on housing conditions, i.e. hygiene
measures applied in the facility. One of the most important measures that
are continuously implemented is milking hygiene procedures, within which special
attention is paid to: hygiene of milkers, hygiene measures before milking, hygiene
measures after milking, as well as hygiene of milking equipment. The milking
hygiene practices is one of the key factors in maintaining the health status of the
mammary gland. The great economic losses that mastitis cause to the dairy industry
requires particular focus in the development and implementation of mastitis
control plans, in which disinfection of udders before and after milking plays a key
role. The development of new disinfectants and their application technologies, with
a good effect on the health of the udder, is one of the future key factors in the
prevention of mammary gland diseases.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022.",
title = "Higijena muže kao faktor prevencije bolesti mlečne žlezde",
pages = "89-100",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2796"
}
Đorđević, M., Janković, L., Drašković, V., Radanović, O., Zdravković, N.,& Teodorović, R.. (2022). Higijena muže kao faktor prevencije bolesti mlečne žlezde. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022.
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 89-100.
https://hdl.handle.net/21.15107/rcub_veterinar_2796
Đorđević M, Janković L, Drašković V, Radanović O, Zdravković N, Teodorović R. Higijena muže kao faktor prevencije bolesti mlečne žlezde. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022.. 2022;:89-100.
https://hdl.handle.net/21.15107/rcub_veterinar_2796 .
Đorđević, Milutin, Janković, Ljiljana, Drašković, Vladimir, Radanović, Oliver, Zdravković, Nemanja, Teodorović, Radislava, "Higijena muže kao faktor prevencije bolesti mlečne žlezde" in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022. (2022):89-100,
https://hdl.handle.net/21.15107/rcub_veterinar_2796 .

Koinfekcija muflona klostridijum vrstama – komparativna analiza patomorfološkog nalaza kod drugih vrsta divljih papkara

Kureljušić, Branislav; Đorđević, Milutin; Milovanović, Bojan; Savić, Božidar; Jezdimirović, Nemanja; Zdravković, Nemanja; Radanović, Oliver; Milićević, Vesna

(Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze, 2022)

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Đorđević, Milutin
AU  - Milovanović, Bojan
AU  - Savić, Božidar
AU  - Jezdimirović, Nemanja
AU  - Zdravković, Nemanja
AU  - Radanović, Oliver
AU  - Milićević, Vesna
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3174
AB  - Муфлон је једна од најцењенијих врста ловне дивљачи која је због растућег тренда
спортског лова увезена и насељена у Србији и према литературним подацима код
ове врсте јављају се исте бактеријске, вирусне и паразитске болести као и код оваца.
У овом раду је описан случај коинфекције Clostridium perfringens типом А,
Clostridium septicum и Clostridium sordelli код муфлона и урађена је компаративна
анализа патоморфолошких промена са другим врстама дивљих папкара.
Женка муфлона пореклом из ловишта са територије града Београда, тешка 40
килограма, у доброј кондицији, достављена је у дијагностичку лабораторију
Научног института за ветеринарство Србије ради утврђивања узрока угинућа.
Анамнестички подаци су указивали на изненадну смрт, а у скорије време такви
случајеви су се често дешавали.
Макроскопски су утврђена масивна крварења у поткожном, интермускуларном
ткиву и на папиларним мишићима срца. Петехије и екхимозе уочене су на
оментуму, мезентеријуму и масном ткиву срца, бубрега и косталној плеури.
Хеморагично-некротични дуодено-јејунитис карактерисао се присуством крвавог
садржаја. Након обдукције, узети су узорци различитих ткива и органа за
хистопатолошку, бактериолошку и молекуларну анализу (PCR). Хистопатолошким
прегледом потврђене су већ установљене макроскопске лезије, али је утврђена
верминозна пнеумонија, мултифокалне некрозе јетре, масивно крварење и
фоликуларна лимфоидна деплеција у слезини. Некротични ентеритис карактерисао
се десквамацијом и некрозом цревних ресица, као и присуством мехурића гаса у
субмукози.
Бактеријске културе из узоркованих ткива и органа идентификоване су применом
стандардних бактериолошких метода и PCR методе као Clostridium perfringens тип
А, Clostridium septicum и Clostridium sordelli.
На основу утврђених макроскопских и хистопатолошких промена и резултата
бактериолошког и молекуларног испитивања, стање септичног шока и токсемије са
дисеминованим масивним крварењем је непосредни узрок угинућа муфлона.
Септично стање је последица ентеротоксемије изазване инфекцијом трима врстама
клостридија, и то Clostridium perfringens тип А, Clostridium septicum и Clostridium
sordelli. На основу спроведене комапартивне анализе може се закључити да је
патолошки налаз врло сличан код различитих врста дивљих папкара.
AB  - Mouflons are one of the most prized game in Serbia, which was imported and
inhabited a lot due to the growing trend of sport hunting and according to literatury
data this species is affected by the same bacterial, viral and parasitic diseases as sheep.
In this paper, the case of concurrent infection by Clostridium perfringens tip A,
Clostridium septicum, and Clostridium sordelli in necropsied mouflon is described. A
comparative analysis of pathomorphological lesions with other wild even-toed
ungulates species was performed.
Female mouflon, weighing 40 kilograms, in good physical condition, was submitted
to the diagnostic laboratory of the Institute of Veterinary Medicine of Serbia for
determining cause of death. The female mouflon was originated from the hunting area
of the city of Belgrade. Anamnestic data indicated sudden death, and recent more such
cases occurred frequently.
Macroscopically massive hemorrhages in subcutaneous, intermuscular tissue and on
papillary muscle were noted. Petechiae and ecchymoses were found on the omentum,
mesentery and adipose tissue of heart, kidney and costal pleura. Haemorrhagicnecrotic duodeno/jejunitis was characterized by hemorrhagic exudate. After necropsy,
samples for histopathological, bacteriological, and molecular examination (PCR)
were taken. Histopathological examination confirmed detected macroscopic lesions,
as well as verminous pneumonia, multifocal liver necroses, massive bleeding in the
spleen and follicular lymphoid depletion. Necrotic enteritis was characterised by
sloughing of intestinal villi as well as the presence of gas bubbles in the submucosa.
Bacterial cultures from sampled organs were identified as Clostridium perfringens
type A, Clostridium septicum, and Clostridium sordelli.
Based on the established macroscopical and histological changes and the results of
the bacteriological, biochemical, and molecular examination, the state of septic shock
and toxemia with disseminated massive bleeding is the immediate cause of mouflon
death. The septic condition is a consequence of enterotoxemia caused by Clostridium
perfringens type A, Clostridium septicum, and Clostridium sordelli infection. Based
on the conducted comparative analysis, it can be concluded that the
pathomorphological findings are very similar in different species of wild even-toed
ungulates.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXIV Simpozijum epizootiologa i epidemiologa /XXIV Epizootiološki dani, Subotica, 27 - 29. april, 2022
T1  - Koinfekcija muflona klostridijum vrstama – komparativna analiza patomorfološkog nalaza kod drugih vrsta divljih papkara
T1  - Coinfection of mouflon by clostridium species – comparative analysis of pathological findings with other wild even-toed ungulates
SP  - 48
EP  - 49
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3174
ER  - 
@conference{
author = "Kureljušić, Branislav and Đorđević, Milutin and Milovanović, Bojan and Savić, Božidar and Jezdimirović, Nemanja and Zdravković, Nemanja and Radanović, Oliver and Milićević, Vesna",
year = "2022",
abstract = "Муфлон је једна од најцењенијих врста ловне дивљачи која је због растућег тренда
спортског лова увезена и насељена у Србији и према литературним подацима код
ове врсте јављају се исте бактеријске, вирусне и паразитске болести као и код оваца.
У овом раду је описан случај коинфекције Clostridium perfringens типом А,
Clostridium septicum и Clostridium sordelli код муфлона и урађена је компаративна
анализа патоморфолошких промена са другим врстама дивљих папкара.
Женка муфлона пореклом из ловишта са територије града Београда, тешка 40
килограма, у доброј кондицији, достављена је у дијагностичку лабораторију
Научног института за ветеринарство Србије ради утврђивања узрока угинућа.
Анамнестички подаци су указивали на изненадну смрт, а у скорије време такви
случајеви су се често дешавали.
Макроскопски су утврђена масивна крварења у поткожном, интермускуларном
ткиву и на папиларним мишићима срца. Петехије и екхимозе уочене су на
оментуму, мезентеријуму и масном ткиву срца, бубрега и косталној плеури.
Хеморагично-некротични дуодено-јејунитис карактерисао се присуством крвавог
садржаја. Након обдукције, узети су узорци различитих ткива и органа за
хистопатолошку, бактериолошку и молекуларну анализу (PCR). Хистопатолошким
прегледом потврђене су већ установљене макроскопске лезије, али је утврђена
верминозна пнеумонија, мултифокалне некрозе јетре, масивно крварење и
фоликуларна лимфоидна деплеција у слезини. Некротични ентеритис карактерисао
се десквамацијом и некрозом цревних ресица, као и присуством мехурића гаса у
субмукози.
Бактеријске културе из узоркованих ткива и органа идентификоване су применом
стандардних бактериолошких метода и PCR методе као Clostridium perfringens тип
А, Clostridium septicum и Clostridium sordelli.
На основу утврђених макроскопских и хистопатолошких промена и резултата
бактериолошког и молекуларног испитивања, стање септичног шока и токсемије са
дисеминованим масивним крварењем је непосредни узрок угинућа муфлона.
Септично стање је последица ентеротоксемије изазване инфекцијом трима врстама
клостридија, и то Clostridium perfringens тип А, Clostridium septicum и Clostridium
sordelli. На основу спроведене комапартивне анализе може се закључити да је
патолошки налаз врло сличан код различитих врста дивљих папкара., Mouflons are one of the most prized game in Serbia, which was imported and
inhabited a lot due to the growing trend of sport hunting and according to literatury
data this species is affected by the same bacterial, viral and parasitic diseases as sheep.
In this paper, the case of concurrent infection by Clostridium perfringens tip A,
Clostridium septicum, and Clostridium sordelli in necropsied mouflon is described. A
comparative analysis of pathomorphological lesions with other wild even-toed
ungulates species was performed.
Female mouflon, weighing 40 kilograms, in good physical condition, was submitted
to the diagnostic laboratory of the Institute of Veterinary Medicine of Serbia for
determining cause of death. The female mouflon was originated from the hunting area
of the city of Belgrade. Anamnestic data indicated sudden death, and recent more such
cases occurred frequently.
Macroscopically massive hemorrhages in subcutaneous, intermuscular tissue and on
papillary muscle were noted. Petechiae and ecchymoses were found on the omentum,
mesentery and adipose tissue of heart, kidney and costal pleura. Haemorrhagicnecrotic duodeno/jejunitis was characterized by hemorrhagic exudate. After necropsy,
samples for histopathological, bacteriological, and molecular examination (PCR)
were taken. Histopathological examination confirmed detected macroscopic lesions,
as well as verminous pneumonia, multifocal liver necroses, massive bleeding in the
spleen and follicular lymphoid depletion. Necrotic enteritis was characterised by
sloughing of intestinal villi as well as the presence of gas bubbles in the submucosa.
Bacterial cultures from sampled organs were identified as Clostridium perfringens
type A, Clostridium septicum, and Clostridium sordelli.
Based on the established macroscopical and histological changes and the results of
the bacteriological, biochemical, and molecular examination, the state of septic shock
and toxemia with disseminated massive bleeding is the immediate cause of mouflon
death. The septic condition is a consequence of enterotoxemia caused by Clostridium
perfringens type A, Clostridium septicum, and Clostridium sordelli infection. Based
on the conducted comparative analysis, it can be concluded that the
pathomorphological findings are very similar in different species of wild even-toed
ungulates.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXIV Simpozijum epizootiologa i epidemiologa /XXIV Epizootiološki dani, Subotica, 27 - 29. april, 2022",
title = "Koinfekcija muflona klostridijum vrstama – komparativna analiza patomorfološkog nalaza kod drugih vrsta divljih papkara, Coinfection of mouflon by clostridium species – comparative analysis of pathological findings with other wild even-toed ungulates",
pages = "48-49",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3174"
}
Kureljušić, B., Đorđević, M., Milovanović, B., Savić, B., Jezdimirović, N., Zdravković, N., Radanović, O.,& Milićević, V.. (2022). Koinfekcija muflona klostridijum vrstama – komparativna analiza patomorfološkog nalaza kod drugih vrsta divljih papkara. in XXIV Simpozijum epizootiologa i epidemiologa /XXIV Epizootiološki dani, Subotica, 27 - 29. april, 2022
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 48-49.
https://hdl.handle.net/21.15107/rcub_veterinar_3174
Kureljušić B, Đorđević M, Milovanović B, Savić B, Jezdimirović N, Zdravković N, Radanović O, Milićević V. Koinfekcija muflona klostridijum vrstama – komparativna analiza patomorfološkog nalaza kod drugih vrsta divljih papkara. in XXIV Simpozijum epizootiologa i epidemiologa /XXIV Epizootiološki dani, Subotica, 27 - 29. april, 2022. 2022;:48-49.
https://hdl.handle.net/21.15107/rcub_veterinar_3174 .
Kureljušić, Branislav, Đorđević, Milutin, Milovanović, Bojan, Savić, Božidar, Jezdimirović, Nemanja, Zdravković, Nemanja, Radanović, Oliver, Milićević, Vesna, "Koinfekcija muflona klostridijum vrstama – komparativna analiza patomorfološkog nalaza kod drugih vrsta divljih papkara" in XXIV Simpozijum epizootiologa i epidemiologa /XXIV Epizootiološki dani, Subotica, 27 - 29. april, 2022 (2022):48-49,
https://hdl.handle.net/21.15107/rcub_veterinar_3174 .

Naša iskustva u primeni biosigurnosnih mera u fazanerijama

Đorđević, Milutin; Radanović, Oliver; Pešić, Branislav

(Beograd : Srpsko veterinarsko društvo, 2022)

TY  - CONF
AU  - Đorđević, Milutin
AU  - Radanović, Oliver
AU  - Pešić, Branislav
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2658
AB  - Fazanerije predstavljaju farmske objekte poluzatvorenog tipa, sa nekoliko proizvodnih celina koje su ciklično povezane i u kojima se gaje jedinke različitih starosnih kategorija. Lokacija fazanerija, istovremeni uzgoj različitih starosnih kategorija unutar ekonomskog dvorišta, uzgoj jedinki u objektima poluzatvorenog tipa, potencijalni uticaj različitih patogenih faktora iz okruženja, definišu fazanerije sa aspekta biosigurnosti kao objekte visokog zdravstvenog rizika. Zbog toga je za uspešnu farmsku proizvodnju fazanske divljači potrebno kontinuirano sprovođenje biosigurnosnih mera u svim fazama tehnološkog postupka proizvodnje. Najvažnije biosigurnosne mere koje se sprovode u fazanerijama su dezinfekcija i deratizacija. U radu su prikazani dosadašnji rezultati efekata sprovođenja navedenih biosigurnosnih mera u fazanerijama.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 33 Savetovanje veterinara Srbije. Zlatibor, 8-11. septembar 2022.
T1  - Naša iskustva u primeni biosigurnosnih mera u fazanerijama
SP  - 123
EP  - 140
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2658
ER  - 
@conference{
author = "Đorđević, Milutin and Radanović, Oliver and Pešić, Branislav",
year = "2022",
abstract = "Fazanerije predstavljaju farmske objekte poluzatvorenog tipa, sa nekoliko proizvodnih celina koje su ciklično povezane i u kojima se gaje jedinke različitih starosnih kategorija. Lokacija fazanerija, istovremeni uzgoj različitih starosnih kategorija unutar ekonomskog dvorišta, uzgoj jedinki u objektima poluzatvorenog tipa, potencijalni uticaj različitih patogenih faktora iz okruženja, definišu fazanerije sa aspekta biosigurnosti kao objekte visokog zdravstvenog rizika. Zbog toga je za uspešnu farmsku proizvodnju fazanske divljači potrebno kontinuirano sprovođenje biosigurnosnih mera u svim fazama tehnološkog postupka proizvodnje. Najvažnije biosigurnosne mere koje se sprovode u fazanerijama su dezinfekcija i deratizacija. U radu su prikazani dosadašnji rezultati efekata sprovođenja navedenih biosigurnosnih mera u fazanerijama.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "33 Savetovanje veterinara Srbije. Zlatibor, 8-11. septembar 2022.",
title = "Naša iskustva u primeni biosigurnosnih mera u fazanerijama",
pages = "123-140",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2658"
}
Đorđević, M., Radanović, O.,& Pešić, B.. (2022). Naša iskustva u primeni biosigurnosnih mera u fazanerijama. in 33 Savetovanje veterinara Srbije. Zlatibor, 8-11. septembar 2022.
Beograd : Srpsko veterinarsko društvo., 123-140.
https://hdl.handle.net/21.15107/rcub_veterinar_2658
Đorđević M, Radanović O, Pešić B. Naša iskustva u primeni biosigurnosnih mera u fazanerijama. in 33 Savetovanje veterinara Srbije. Zlatibor, 8-11. septembar 2022.. 2022;:123-140.
https://hdl.handle.net/21.15107/rcub_veterinar_2658 .
Đorđević, Milutin, Radanović, Oliver, Pešić, Branislav, "Naša iskustva u primeni biosigurnosnih mera u fazanerijama" in 33 Savetovanje veterinara Srbije. Zlatibor, 8-11. septembar 2022. (2022):123-140,
https://hdl.handle.net/21.15107/rcub_veterinar_2658 .

Diferencijalna dijagnostika bolesti svinja koje se karakterišu krvavljenjem u digestivnom traktu

Kureljušić, Branislav; Dobrosavljević, Ivan; Milovanoviić, Bojan; Jezdimirović, Nemanja; Radanović, Oliver; Milićević, Vesna; Bojkovski, Jovan; Prodanov-Radulović, Jasna; Savić, Božidar

(Požarevac : Sitograf RM : Veterinarski specijalistički institut, 2022)

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Dobrosavljević, Ivan
AU  - Milovanoviić, Bojan
AU  - Jezdimirović, Nemanja
AU  - Radanović, Oliver
AU  - Milićević, Vesna
AU  - Bojkovski, Jovan
AU  - Prodanov-Radulović, Jasna
AU  - Savić, Božidar
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3420
AB  - Krvavljenja u digestivnom traktu svinja se mogu javiti kod različitih proizvodnih
kategorija svinja, ali najčešće su vezana za period posle zalučenja i tov. Krvavljenja u
digestivnom traktu kod prasadi na sisi se najčešće javljaju kod akutnog klostridijalnog enteritisa
prasadi na sisi koji je u literaturi poznat i kao hemoragično-nekrotični enteritis. Tokom odgoja
prasadi i kasnije u tovu može se javiti hemoragična proliferativna enteropatija koja se
karakteriše vrlo intenzivnim krvavljenjem u ileumu gde su prisutni ugrušci sveže krvi, ali bez
prisutnih lezija na samoj sluznici (nema ulceracija). Sluznica je pri tome naborana kao posledica
adenomatozne proliferacije nezrelih ćelija crevnih kripti, a hemoragična dijareja je česta pojava.
Ezofagogastrični ulkus i ulceracije u želucu svinja mogu dovesti do manjeg subkliničkog
gubitka krvi ili značajnijeg krvavljenja koje dovodi do melene i uginuća od posledica
iskrvarenja. Kod dizenterije svinja, javlja se ulcerozni tiflokolitis koji se karakteriše prisustvom
hemoragičnog sadržaja sa fibrinonekrotičnim membranama, a klinički rezultuje pojavom
mukohemoragične dijareje koja sadrži primese sveže krvi. Infekcija Trichuris suis takođe može
da prouzrokuje mukohemoragičnu dijareju kod teže infestacije. Sveža krv u fecesu svinja može
se ustanoviti kod svinja sa anorektalnom traumom kao što je slučaj kod prolapsusa rektuma.
Trovanje antikoagulantnim rodenticidima može takođe prouzrokovati intestinalna krvavljenja.
Poremećaj u položaju creva koji se javlja kod intestinalne torzije su neizostavno praćena
pojavom hemoragičnog infarkta creva i prisustvom sveže krvi u lumenu creva. Za razliku od
ovog stanja gde je torzija po uzdužnoj osi mezenterijuma evidentna i zahvata najčešće i tanko i
debelo crevo, krvavljenja u tankim i debelim crevima se mogu javiti i kod hemoragične bolesti
creva (“hemorrhagic bowel disease”). Oba ova stanja završavaju se perakutnim uginućem pre
nego što se pojavi krv u fecesu.
Stanja praćena krvavljenjem u digestivnom traktu svinja su urgentna stanja i zahtevaju
brzu dijagnostiku i uvođenje odgovarajućih terapijskih protokola ukoliko je efikasna terapija za
takvo stanje dostupna.
PB  - Požarevac : Sitograf RM : Veterinarski specijalistički institut
C3  - 19. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 2 - 3 jun, 2022
T1  - Diferencijalna dijagnostika bolesti svinja koje se karakterišu krvavljenjem u digestivnom traktu
SP  - 16
EP  - 16
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3420
ER  - 
@conference{
author = "Kureljušić, Branislav and Dobrosavljević, Ivan and Milovanoviić, Bojan and Jezdimirović, Nemanja and Radanović, Oliver and Milićević, Vesna and Bojkovski, Jovan and Prodanov-Radulović, Jasna and Savić, Božidar",
year = "2022",
abstract = "Krvavljenja u digestivnom traktu svinja se mogu javiti kod različitih proizvodnih
kategorija svinja, ali najčešće su vezana za period posle zalučenja i tov. Krvavljenja u
digestivnom traktu kod prasadi na sisi se najčešće javljaju kod akutnog klostridijalnog enteritisa
prasadi na sisi koji je u literaturi poznat i kao hemoragično-nekrotični enteritis. Tokom odgoja
prasadi i kasnije u tovu može se javiti hemoragična proliferativna enteropatija koja se
karakteriše vrlo intenzivnim krvavljenjem u ileumu gde su prisutni ugrušci sveže krvi, ali bez
prisutnih lezija na samoj sluznici (nema ulceracija). Sluznica je pri tome naborana kao posledica
adenomatozne proliferacije nezrelih ćelija crevnih kripti, a hemoragična dijareja je česta pojava.
Ezofagogastrični ulkus i ulceracije u želucu svinja mogu dovesti do manjeg subkliničkog
gubitka krvi ili značajnijeg krvavljenja koje dovodi do melene i uginuća od posledica
iskrvarenja. Kod dizenterije svinja, javlja se ulcerozni tiflokolitis koji se karakteriše prisustvom
hemoragičnog sadržaja sa fibrinonekrotičnim membranama, a klinički rezultuje pojavom
mukohemoragične dijareje koja sadrži primese sveže krvi. Infekcija Trichuris suis takođe može
da prouzrokuje mukohemoragičnu dijareju kod teže infestacije. Sveža krv u fecesu svinja može
se ustanoviti kod svinja sa anorektalnom traumom kao što je slučaj kod prolapsusa rektuma.
Trovanje antikoagulantnim rodenticidima može takođe prouzrokovati intestinalna krvavljenja.
Poremećaj u položaju creva koji se javlja kod intestinalne torzije su neizostavno praćena
pojavom hemoragičnog infarkta creva i prisustvom sveže krvi u lumenu creva. Za razliku od
ovog stanja gde je torzija po uzdužnoj osi mezenterijuma evidentna i zahvata najčešće i tanko i
debelo crevo, krvavljenja u tankim i debelim crevima se mogu javiti i kod hemoragične bolesti
creva (“hemorrhagic bowel disease”). Oba ova stanja završavaju se perakutnim uginućem pre
nego što se pojavi krv u fecesu.
Stanja praćena krvavljenjem u digestivnom traktu svinja su urgentna stanja i zahtevaju
brzu dijagnostiku i uvođenje odgovarajućih terapijskih protokola ukoliko je efikasna terapija za
takvo stanje dostupna.",
publisher = "Požarevac : Sitograf RM : Veterinarski specijalistički institut",
journal = "19. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 2 - 3 jun, 2022",
title = "Diferencijalna dijagnostika bolesti svinja koje se karakterišu krvavljenjem u digestivnom traktu",
pages = "16-16",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3420"
}
Kureljušić, B., Dobrosavljević, I., Milovanoviić, B., Jezdimirović, N., Radanović, O., Milićević, V., Bojkovski, J., Prodanov-Radulović, J.,& Savić, B.. (2022). Diferencijalna dijagnostika bolesti svinja koje se karakterišu krvavljenjem u digestivnom traktu. in 19. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 2 - 3 jun, 2022
Požarevac : Sitograf RM : Veterinarski specijalistički institut., 16-16.
https://hdl.handle.net/21.15107/rcub_veterinar_3420
Kureljušić B, Dobrosavljević I, Milovanoviić B, Jezdimirović N, Radanović O, Milićević V, Bojkovski J, Prodanov-Radulović J, Savić B. Diferencijalna dijagnostika bolesti svinja koje se karakterišu krvavljenjem u digestivnom traktu. in 19. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 2 - 3 jun, 2022. 2022;:16-16.
https://hdl.handle.net/21.15107/rcub_veterinar_3420 .
Kureljušić, Branislav, Dobrosavljević, Ivan, Milovanoviić, Bojan, Jezdimirović, Nemanja, Radanović, Oliver, Milićević, Vesna, Bojkovski, Jovan, Prodanov-Radulović, Jasna, Savić, Božidar, "Diferencijalna dijagnostika bolesti svinja koje se karakterišu krvavljenjem u digestivnom traktu" in 19. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 2 - 3 jun, 2022 (2022):16-16,
https://hdl.handle.net/21.15107/rcub_veterinar_3420 .

Findings L. Monocytogenes and antimicrobial sensitivity during the period 2020-2022

Zdravković, Nemanja; Radanović, Oliver; Kureljušić, Jasna; Rokvić, Nikola; Ninković, Milan; Savić Radovanović, Radoslava; Jakić-Dimić, Dobrila

(Banja Luka : Veterinarska komora Republike Srpske, 2022)

TY  - CONF
AU  - Zdravković, Nemanja
AU  - Radanović, Oliver
AU  - Kureljušić, Jasna
AU  - Rokvić, Nikola
AU  - Ninković, Milan
AU  - Savić Radovanović, Radoslava
AU  - Jakić-Dimić, Dobrila
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2765
AB  - Since the late years of the 20th century, listeriosis has been considered a
major public health concern. In the past years, Listeria monocytogenes has
been connected to more outbreaks of food-borne disease in humans with a
significant increasing trend in 2008. While it has been established that foodborne transmission constitutes the main acquisition route of listeriosis. Little
is known about L. monocytogenes antimicrobial resistance, especially for
non-human-origin isolates (Granier, 2011). Literature findings are that the most
of healthy humans are not significantly affected by the intake of L. monocytogenes in foods. The aim of the paper is to show an antimicrobial susceptibility
of L. monocytogenes isolates in the Veterinary Institute of Serbia in the last
2 years. In a total of 7 isolates of L. monocytogenes in general bacteriology
laboratory mainly origin from abortions of cattle, and others are from various
sources. Isolates have been isolated and identified following specific protocols
by selective broth enrichment and agar isolation procedure by OIE Manual of
Diagnostic Tests and Vaccines for Terrestrial Animals chapter 3.10.5 or similar
ISO 11290 standard for food chain isolates. Antimicrobial susceptibility has
been done by standard Kirby Bauer method ISO 20776. In general, all isolates
have been susceptible to penicillins (alone or with beta lactamase inhibitor),
tetracyclins, enrofloxacine and florfenicol. Some isolates showed resistance to
cephalosporins (28.57%), streptomycin (43.86%) and sulfonamides (14.29%).
 It seems that L. monocytogenes isolates from pathological processes in
animals and animal origin food still don’t exibit increased antimicrobial
insusceptibility in Serbia. Although Listeria spp. has been generally
reported susceptible to almost all antimicrobials, we still don’t agree
with foreign consideration that the emergence and spread of antimicrobial-resistant Listeria spp. has been attributed to the overuse of
antibiotics in disease treatments in domestic livestock.
AB  - Од касних година 20. века, листериоза се сматра главним проблемом јавног
здравља. Последњих година, Listeria monocitogenes је била повезана са више
избијања болести које се преносе храном код људи са значајним трендом
раста у 2008. Док је установљено да пренос путем хране представља главни
пут стицања листериозе. Мало се зна о антимикробној резистенцији L.
monocitogenes, посебно за изолате који нису људског порекла (Граниер,
2011). Литературни налази показују да већина здравих људи није значајно
погођена уносом L. monocitogenes у храну. Циљ рада је да се прикаже
антимикробна осетљивост изолата L. monocitogenes у Ветеринарском
институту Србије у последње 2 године. У укупно 7 изолата L. monocitogenes у
општој бактериолошкој лабораторији углавном потичу из абортуса говеда,
а остали су из различитих извора. Изолати су изоловани и идентификовани
према специфичним протоколима селективним обогаћивањем бујона и
процедуром изолације на агару према ОИЕ приручнику за дијагностичке
тестове и вакцине за копнене животиње, поглавље 3.10.5 или сличан
стандард ISO 11290 за изолате ланца исхране. Антимикробна осетљивост
је одређена стандардном Кирби Бауер методом ISO 20776. Генерално, сви
изолати су били осетљиви на пеницилине (сам или са инхибитором бета
лактамазе), тетрациклине, енрофлоксацин и флорфеникол. Неки изолати
су показали резистенцију на цефалоспорине (28,57%), стрептомицин
(43,86%) и сулфонамиде (14,29%).
Чини се да изолати L. monocitogenes из патолошких процеса у животињама и
храна животињског порекла још увек не показују повећану антимикробну
неосетљивост у Србији. Иако Listeria spp. је генерално пријављено да је
подложан скоро свим антимикробним средствима, наше искуство није у
корелацији мишљењем да је појава и ширење Listeria spp. се приписује
прекомерној употреби антибиотика у лечењу болести домаћих животиња.
PB  - Banja Luka : Veterinarska komora Republike Srpske
C3  - 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15-18. jun 2022
T1  - Findings L. Monocytogenes and antimicrobial sensitivity during the period 2020-2022
T1  - Nalaz L. Monocytogenes i antimikrobna osetljivost tokom perioda 2020-2022
SP  - 324
EP  - 325
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2765
ER  - 
@conference{
author = "Zdravković, Nemanja and Radanović, Oliver and Kureljušić, Jasna and Rokvić, Nikola and Ninković, Milan and Savić Radovanović, Radoslava and Jakić-Dimić, Dobrila",
year = "2022",
abstract = "Since the late years of the 20th century, listeriosis has been considered a
major public health concern. In the past years, Listeria monocytogenes has
been connected to more outbreaks of food-borne disease in humans with a
significant increasing trend in 2008. While it has been established that foodborne transmission constitutes the main acquisition route of listeriosis. Little
is known about L. monocytogenes antimicrobial resistance, especially for
non-human-origin isolates (Granier, 2011). Literature findings are that the most
of healthy humans are not significantly affected by the intake of L. monocytogenes in foods. The aim of the paper is to show an antimicrobial susceptibility
of L. monocytogenes isolates in the Veterinary Institute of Serbia in the last
2 years. In a total of 7 isolates of L. monocytogenes in general bacteriology
laboratory mainly origin from abortions of cattle, and others are from various
sources. Isolates have been isolated and identified following specific protocols
by selective broth enrichment and agar isolation procedure by OIE Manual of
Diagnostic Tests and Vaccines for Terrestrial Animals chapter 3.10.5 or similar
ISO 11290 standard for food chain isolates. Antimicrobial susceptibility has
been done by standard Kirby Bauer method ISO 20776. In general, all isolates
have been susceptible to penicillins (alone or with beta lactamase inhibitor),
tetracyclins, enrofloxacine and florfenicol. Some isolates showed resistance to
cephalosporins (28.57%), streptomycin (43.86%) and sulfonamides (14.29%).
 It seems that L. monocytogenes isolates from pathological processes in
animals and animal origin food still don’t exibit increased antimicrobial
insusceptibility in Serbia. Although Listeria spp. has been generally
reported susceptible to almost all antimicrobials, we still don’t agree
with foreign consideration that the emergence and spread of antimicrobial-resistant Listeria spp. has been attributed to the overuse of
antibiotics in disease treatments in domestic livestock., Од касних година 20. века, листериоза се сматра главним проблемом јавног
здравља. Последњих година, Listeria monocitogenes је била повезана са више
избијања болести које се преносе храном код људи са значајним трендом
раста у 2008. Док је установљено да пренос путем хране представља главни
пут стицања листериозе. Мало се зна о антимикробној резистенцији L.
monocitogenes, посебно за изолате који нису људског порекла (Граниер,
2011). Литературни налази показују да већина здравих људи није значајно
погођена уносом L. monocitogenes у храну. Циљ рада је да се прикаже
антимикробна осетљивост изолата L. monocitogenes у Ветеринарском
институту Србије у последње 2 године. У укупно 7 изолата L. monocitogenes у
општој бактериолошкој лабораторији углавном потичу из абортуса говеда,
а остали су из различитих извора. Изолати су изоловани и идентификовани
према специфичним протоколима селективним обогаћивањем бујона и
процедуром изолације на агару према ОИЕ приручнику за дијагностичке
тестове и вакцине за копнене животиње, поглавље 3.10.5 или сличан
стандард ISO 11290 за изолате ланца исхране. Антимикробна осетљивост
је одређена стандардном Кирби Бауер методом ISO 20776. Генерално, сви
изолати су били осетљиви на пеницилине (сам или са инхибитором бета
лактамазе), тетрациклине, енрофлоксацин и флорфеникол. Неки изолати
су показали резистенцију на цефалоспорине (28,57%), стрептомицин
(43,86%) и сулфонамиде (14,29%).
Чини се да изолати L. monocitogenes из патолошких процеса у животињама и
храна животињског порекла још увек не показују повећану антимикробну
неосетљивост у Србији. Иако Listeria spp. је генерално пријављено да је
подложан скоро свим антимикробним средствима, наше искуство није у
корелацији мишљењем да је појава и ширење Listeria spp. се приписује
прекомерној употреби антибиотика у лечењу болести домаћих животиња.",
publisher = "Banja Luka : Veterinarska komora Republike Srpske",
journal = "27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15-18. jun 2022",
title = "Findings L. Monocytogenes and antimicrobial sensitivity during the period 2020-2022, Nalaz L. Monocytogenes i antimikrobna osetljivost tokom perioda 2020-2022",
pages = "324-325",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2765"
}
Zdravković, N., Radanović, O., Kureljušić, J., Rokvić, N., Ninković, M., Savić Radovanović, R.,& Jakić-Dimić, D.. (2022). Findings L. Monocytogenes and antimicrobial sensitivity during the period 2020-2022. in 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15-18. jun 2022
Banja Luka : Veterinarska komora Republike Srpske., 324-325.
https://hdl.handle.net/21.15107/rcub_veterinar_2765
Zdravković N, Radanović O, Kureljušić J, Rokvić N, Ninković M, Savić Radovanović R, Jakić-Dimić D. Findings L. Monocytogenes and antimicrobial sensitivity during the period 2020-2022. in 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15-18. jun 2022. 2022;:324-325.
https://hdl.handle.net/21.15107/rcub_veterinar_2765 .
Zdravković, Nemanja, Radanović, Oliver, Kureljušić, Jasna, Rokvić, Nikola, Ninković, Milan, Savić Radovanović, Radoslava, Jakić-Dimić, Dobrila, "Findings L. Monocytogenes and antimicrobial sensitivity during the period 2020-2022" in 27. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15-18. jun 2022 (2022):324-325,
https://hdl.handle.net/21.15107/rcub_veterinar_2765 .

Important bacterial diseases and their control in rainbow trout in Serbian aquaculture

Radosavljević, Vladimir; Zdravković, Nemanja; Veljović, Ljubiša; Radanović, Oliver

(University of Belgrade, Faculty of Veterinary Medicine, 2022)

TY  - JOUR
AU  - Radosavljević, Vladimir
AU  - Zdravković, Nemanja
AU  - Veljović, Ljubiša
AU  - Radanović, Oliver
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2709
AB  - Global freshwater fish production in aquaculture has grown rapidly in recent decades. This constant growth, involving novel forms of intensive aquaculture, has increased global  movements  of  fish  and  boosted  various  anthropogenic  stresses  to  aquatic ecosystems, so rainbow trout aquaculture has encountered the emergence and outbreaks of many bacterial diseases. Due to the need to effectively prevent and control disease outbreaks, vaccines have become an important technology in intensive trout aquaculture. In this review, the applications of specific vaccines against important bacterial diseases of rainbow trout in Serbian aquaculture are summarized.
PB  - University of Belgrade, Faculty of Veterinary Medicine
T2  - Veterinarski Glasnik
T1  - Important bacterial diseases and their control in rainbow trout in Serbian aquaculture
VL  - 76
IS  - 2
SP  - 103
SP  - 112
DO  - 10.2298/VETGL211217006R
ER  - 
@article{
author = "Radosavljević, Vladimir and Zdravković, Nemanja and Veljović, Ljubiša and Radanović, Oliver",
year = "2022",
abstract = "Global freshwater fish production in aquaculture has grown rapidly in recent decades. This constant growth, involving novel forms of intensive aquaculture, has increased global  movements  of  fish  and  boosted  various  anthropogenic  stresses  to  aquatic ecosystems, so rainbow trout aquaculture has encountered the emergence and outbreaks of many bacterial diseases. Due to the need to effectively prevent and control disease outbreaks, vaccines have become an important technology in intensive trout aquaculture. In this review, the applications of specific vaccines against important bacterial diseases of rainbow trout in Serbian aquaculture are summarized.",
publisher = "University of Belgrade, Faculty of Veterinary Medicine",
journal = "Veterinarski Glasnik",
title = "Important bacterial diseases and their control in rainbow trout in Serbian aquaculture",
volume = "76",
number = "2",
pages = "103-112",
doi = "10.2298/VETGL211217006R"
}
Radosavljević, V., Zdravković, N., Veljović, L.,& Radanović, O.. (2022). Important bacterial diseases and their control in rainbow trout in Serbian aquaculture. in Veterinarski Glasnik
University of Belgrade, Faculty of Veterinary Medicine., 76(2), 103.
https://doi.org/10.2298/VETGL211217006R
Radosavljević V, Zdravković N, Veljović L, Radanović O. Important bacterial diseases and their control in rainbow trout in Serbian aquaculture. in Veterinarski Glasnik. 2022;76(2):103.
doi:10.2298/VETGL211217006R .
Radosavljević, Vladimir, Zdravković, Nemanja, Veljović, Ljubiša, Radanović, Oliver, "Important bacterial diseases and their control in rainbow trout in Serbian aquaculture" in Veterinarski Glasnik, 76, no. 2 (2022):103,
https://doi.org/10.2298/VETGL211217006R . .

The role of bacterial infections in the development of respiratory diseases in swine

Bojkovski, Jovan; Pavlović, Ivan; Vujanac, Ivan; Arsić, Sveta; Nedić, Sreten; Aniţă, Dragoş Constantin; Oslbanu, Luanda; Anita, Adriana Elena; Zdravković, Nemanja; Radanović, Oliver; Prodanov-Radulović, Jasna; Karać, Petar; Prodanović, Radiša

(Iasi : Ion Ionescu de la Brad, 2021)

TY  - JOUR
AU  - Bojkovski, Jovan
AU  - Pavlović, Ivan
AU  - Vujanac, Ivan
AU  - Arsić, Sveta
AU  - Nedić, Sreten
AU  - Aniţă, Dragoş Constantin
AU  - Oslbanu, Luanda
AU  - Anita, Adriana Elena
AU  - Zdravković, Nemanja
AU  - Radanović, Oliver
AU  - Prodanov-Radulović, Jasna
AU  - Karać, Petar
AU  - Prodanović, Radiša
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3499
AB  - Respiratory disease of bacterial etiology is a serious health problem on commercial farms.Pig production on commercial farms means keeping a large number of pigs in a relatively small space with a high level of technological organization of the production process. Intensive utilization of accommodation capacities, early weaning of piglets, inadequate microclimatic conditions for most of the statised categories and deficits in nutrition have conditioned the appearance of production or technological diseases. Production diseases of bacterial etiology are presented in this review paper. Diseases of bacterial etiology that occur at all stages of technological production are: atrophic rhinitis, enzootic swine pneumonia, pneumonia caused by pasteurellosis, bordetella, pneumonia caused by A. pleuropneumoniae, pneumonia caused by Haemophilus parasuis and pneumonia caused by Streptococcus. We have described the possibility of prophylaxis of these production diseases of bacterial etiology and the possibility of their control. These manufactured diseases cause economic losses (deaths, reduced daily gain, extended fattening time and treatment costs.
PB  - Iasi : Ion Ionescu de la Brad
T2  - Scientific papers - Veterinary Medicine
T1  - The role of bacterial infections in the development of respiratory diseases in swine
VL  - 64
IS  - 2
SP  - 70
EP  - 75
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3499
ER  - 
@article{
author = "Bojkovski, Jovan and Pavlović, Ivan and Vujanac, Ivan and Arsić, Sveta and Nedić, Sreten and Aniţă, Dragoş Constantin and Oslbanu, Luanda and Anita, Adriana Elena and Zdravković, Nemanja and Radanović, Oliver and Prodanov-Radulović, Jasna and Karać, Petar and Prodanović, Radiša",
year = "2021",
abstract = "Respiratory disease of bacterial etiology is a serious health problem on commercial farms.Pig production on commercial farms means keeping a large number of pigs in a relatively small space with a high level of technological organization of the production process. Intensive utilization of accommodation capacities, early weaning of piglets, inadequate microclimatic conditions for most of the statised categories and deficits in nutrition have conditioned the appearance of production or technological diseases. Production diseases of bacterial etiology are presented in this review paper. Diseases of bacterial etiology that occur at all stages of technological production are: atrophic rhinitis, enzootic swine pneumonia, pneumonia caused by pasteurellosis, bordetella, pneumonia caused by A. pleuropneumoniae, pneumonia caused by Haemophilus parasuis and pneumonia caused by Streptococcus. We have described the possibility of prophylaxis of these production diseases of bacterial etiology and the possibility of their control. These manufactured diseases cause economic losses (deaths, reduced daily gain, extended fattening time and treatment costs.",
publisher = "Iasi : Ion Ionescu de la Brad",
journal = "Scientific papers - Veterinary Medicine",
title = "The role of bacterial infections in the development of respiratory diseases in swine",
volume = "64",
number = "2",
pages = "70-75",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3499"
}
Bojkovski, J., Pavlović, I., Vujanac, I., Arsić, S., Nedić, S., Aniţă, D. C., Oslbanu, L., Anita, A. E., Zdravković, N., Radanović, O., Prodanov-Radulović, J., Karać, P.,& Prodanović, R.. (2021). The role of bacterial infections in the development of respiratory diseases in swine. in Scientific papers - Veterinary Medicine
Iasi : Ion Ionescu de la Brad., 64(2), 70-75.
https://hdl.handle.net/21.15107/rcub_veterinar_3499
Bojkovski J, Pavlović I, Vujanac I, Arsić S, Nedić S, Aniţă DC, Oslbanu L, Anita AE, Zdravković N, Radanović O, Prodanov-Radulović J, Karać P, Prodanović R. The role of bacterial infections in the development of respiratory diseases in swine. in Scientific papers - Veterinary Medicine. 2021;64(2):70-75.
https://hdl.handle.net/21.15107/rcub_veterinar_3499 .
Bojkovski, Jovan, Pavlović, Ivan, Vujanac, Ivan, Arsić, Sveta, Nedić, Sreten, Aniţă, Dragoş Constantin, Oslbanu, Luanda, Anita, Adriana Elena, Zdravković, Nemanja, Radanović, Oliver, Prodanov-Radulović, Jasna, Karać, Petar, Prodanović, Radiša, "The role of bacterial infections in the development of respiratory diseases in swine" in Scientific papers - Veterinary Medicine, 64, no. 2 (2021):70-75,
https://hdl.handle.net/21.15107/rcub_veterinar_3499 .

A Salmonella enterica subspecies enterica serovar Choleraesuis outbreak in weaned piglets in Serbia: clinical signs, pathologic changes, and microbiologic features

Savić, Božidar; Zdravković, Namanja; Radanović, Oliver; Jezdimirović, Nemanja; Kureljušić, Branislav; Stevančević, Ognjen

(SAGE Publications, 2021)

TY  - JOUR
AU  - Savić, Božidar
AU  - Zdravković, Namanja
AU  - Radanović, Oliver
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Branislav
AU  - Stevančević, Ognjen
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2512
AB  - Salmonella enterica subspecies enterica serovar Choleraesuis is rarely detected in Europe, but the clinical
disease has been reported in wild boars. We describe here the clinical findings, pathologic changes, and microbiologic features
of swine salmonellosis caused by S. enterica serovar Choleraesuis in weaned piglets in Serbia. In April 2019, on a large
farrow-to-finish pig farm, increased mortality was reported in weaned piglets, marked by lethargy, anorexia, pyrexia, and
respiratory distress. Gross pathology revealed dermal cyanosis, mesenteric lymphadenopathy, splenomegaly, hepatomegaly,
interstitial pneumonia, and colitis. By direct culturing of lung, liver, spleen, and lymph nodes, S. enterica ser. Choleraesuis
variant Kunzendorf was isolated after years of absence of the disease in pig farms in Europe. The source of this salmonellosis
outbreak caused by S. enterica ser. Choleraesuis remains unknown.
PB  - SAGE Publications
T2  - Journal of Veterinary Diagnostic Investigation
T1  - A Salmonella enterica subspecies enterica serovar Choleraesuis outbreak in weaned piglets in Serbia: clinical signs, pathologic changes, and microbiologic features
VL  - 33
IS  - 5
SP  - 993
EP  - 996
DO  - 10.1177/10406387211025507
ER  - 
@article{
author = "Savić, Božidar and Zdravković, Namanja and Radanović, Oliver and Jezdimirović, Nemanja and Kureljušić, Branislav and Stevančević, Ognjen",
year = "2021",
abstract = "Salmonella enterica subspecies enterica serovar Choleraesuis is rarely detected in Europe, but the clinical
disease has been reported in wild boars. We describe here the clinical findings, pathologic changes, and microbiologic features
of swine salmonellosis caused by S. enterica serovar Choleraesuis in weaned piglets in Serbia. In April 2019, on a large
farrow-to-finish pig farm, increased mortality was reported in weaned piglets, marked by lethargy, anorexia, pyrexia, and
respiratory distress. Gross pathology revealed dermal cyanosis, mesenteric lymphadenopathy, splenomegaly, hepatomegaly,
interstitial pneumonia, and colitis. By direct culturing of lung, liver, spleen, and lymph nodes, S. enterica ser. Choleraesuis
variant Kunzendorf was isolated after years of absence of the disease in pig farms in Europe. The source of this salmonellosis
outbreak caused by S. enterica ser. Choleraesuis remains unknown.",
publisher = "SAGE Publications",
journal = "Journal of Veterinary Diagnostic Investigation",
title = "A Salmonella enterica subspecies enterica serovar Choleraesuis outbreak in weaned piglets in Serbia: clinical signs, pathologic changes, and microbiologic features",
volume = "33",
number = "5",
pages = "993-996",
doi = "10.1177/10406387211025507"
}
Savić, B., Zdravković, N., Radanović, O., Jezdimirović, N., Kureljušić, B.,& Stevančević, O.. (2021). A Salmonella enterica subspecies enterica serovar Choleraesuis outbreak in weaned piglets in Serbia: clinical signs, pathologic changes, and microbiologic features. in Journal of Veterinary Diagnostic Investigation
SAGE Publications., 33(5), 993-996.
https://doi.org/10.1177/10406387211025507
Savić B, Zdravković N, Radanović O, Jezdimirović N, Kureljušić B, Stevančević O. A Salmonella enterica subspecies enterica serovar Choleraesuis outbreak in weaned piglets in Serbia: clinical signs, pathologic changes, and microbiologic features. in Journal of Veterinary Diagnostic Investigation. 2021;33(5):993-996.
doi:10.1177/10406387211025507 .
Savić, Božidar, Zdravković, Namanja, Radanović, Oliver, Jezdimirović, Nemanja, Kureljušić, Branislav, Stevančević, Ognjen, "A Salmonella enterica subspecies enterica serovar Choleraesuis outbreak in weaned piglets in Serbia: clinical signs, pathologic changes, and microbiologic features" in Journal of Veterinary Diagnostic Investigation, 33, no. 5 (2021):993-996,
https://doi.org/10.1177/10406387211025507 . .
8

Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study

Zdravković, Nemanja; Radanović, Oliver; Ninković, Milan; Savić Radovanović, Radoslava; Rajić-Savić, Nataša; Marjanović, Đorđe; Bojkovski, Jovan

(Institute for Animal Husbandry, Belgrade-Zemun, Serbia, 2021)

TY  - CONF
AU  - Zdravković, Nemanja
AU  - Radanović, Oliver
AU  - Ninković, Milan
AU  - Savić Radovanović, Radoslava
AU  - Rajić-Savić, Nataša
AU  - Marjanović, Đorđe
AU  - Bojkovski, Jovan
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2311
AB  - Antimicrobial therapy is important tool in fighting infectious
diseases. The significance of the role of antimicrobials in nature remains vastly
uninvestigated. Plants produce secondary metabolites for, among other functions,
natural protection against microbial infection. The aim of this research was to
investigate antimicrobial effects of 5 different essential oils and 5 main constituents
of plant essential oils toward some of the common veterinary microbial pathogens.
Plant etheric oils (EO) of oregano (Origanum vulgare L.), black caraway (Nigella
sativa L.), sandalwood (Santalum album L.), peppermint (Mentha balsamea Wild.)
and eucalyptus (Eucalyptus obliqua L'Hér.) and active components of etheric oils:
D-limonene, D-α pinene, thymol, carvacrol and cynamaldehyde were tested for
antimicriobial activity against referent strains of: Staphylococcus aureus,
Methicilin resistant S. aureus (MRSA), Escherichia coli; as well as against clinical
isolates of: Staphylococcus pseudintermedius, E. coli, Pseudomonas aeruginosa
and yeast Candida sp. For each etheric oil and active compound minimal inhibitory
concentrations (MIC) are observed by method of broth microdilution. Results of
these investigations have shown that active components of the EO have stronger
antimicrobial effect than complete formulation of essential oils used in the study.
Among tested EOs the most potent was the peppermint etheric oil, while carvacrol
showed the strongest antimicrobial effect among active components of EO.
Interesting finding is that there was almost no difference among MICs between
referent S. aureus and MRSA.
AB  - Antimikrobna terapija je važno sredstvo u borbi protiv zaraznih bolesti. Značaj
uloge antimikrobnih sredstava u prirodi ostaje neistražen zbog prilagođavanja
patogena različitim oblicima rezistencije. Biljke proizvode sekundarne metabolite,
između ostalog i za prirodnu zaštitu od mikrobne infekcije. Cilj ovog istraživanja
bio je istražiti antimikrobne efekte 5 različitih esencijalnih ulja i 5 glavnih
sastojaka biljnih etarskih ulja na neke od uobičajenih veterinarskih mikrobnih
patogena. Biljna eterična ulja (EO) origana (Origanum vulgare L.), crnog kima
(Nigella sativa L.), sandalovine (Santalum album L.), nane (Mentha balsamea
Wild.) i eukaliptusa (Eucalyptus obliqua L'Hér.) kao i aktivnih komponenti: Dlimonen,
D-α pinen, timol, karvakrol i cinamaldehid testirani su na antimikrobnu
aktivnost protiv referentnih sojeva: Staphylococcus aureus, S. aureus rezistentne na
meticilin (MRSA), Escherichia coli kao i protiv kliničkih izolata: Staphylococcus
pseudintermedius, E. coli, Pseudomonas aeruginosa i kvasca Candida sp. Za svako
eterično ulje i aktivno jedinjenje dobijene su minimalne inhibitorne koncentracije
(MIK) mikrodilucionom metodom u bujonu. Rezultati su pokazali da aktivne
komponente EO imaju jači antimikrobni efekat od EO sa istom odgovarajućom
dominantnom komponentom. Među testiranim EO najmoćnije je bilo eterično ulje
nane, dok je karvakrol pokazao najjači antimikrobni efekat među aktivnim
komponentama EO. Zanimljiv nalaz je da gotovo nije bilo razlike među MIK
između referentne S. aureus i MRSA.
PB  - Institute for Animal Husbandry, Belgrade-Zemun, Serbia
C3  - 13th International Symposium: Modern trends in livestock production
T1  - Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study
T1  - Aktivnost nekih biljnih eteričnih ulja protiv čestih izolata u veterinarskoj bakteriologiji - pilot studija
SP  - 552
EP  - 560
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2311
ER  - 
@conference{
author = "Zdravković, Nemanja and Radanović, Oliver and Ninković, Milan and Savić Radovanović, Radoslava and Rajić-Savić, Nataša and Marjanović, Đorđe and Bojkovski, Jovan",
year = "2021",
abstract = "Antimicrobial therapy is important tool in fighting infectious
diseases. The significance of the role of antimicrobials in nature remains vastly
uninvestigated. Plants produce secondary metabolites for, among other functions,
natural protection against microbial infection. The aim of this research was to
investigate antimicrobial effects of 5 different essential oils and 5 main constituents
of plant essential oils toward some of the common veterinary microbial pathogens.
Plant etheric oils (EO) of oregano (Origanum vulgare L.), black caraway (Nigella
sativa L.), sandalwood (Santalum album L.), peppermint (Mentha balsamea Wild.)
and eucalyptus (Eucalyptus obliqua L'Hér.) and active components of etheric oils:
D-limonene, D-α pinene, thymol, carvacrol and cynamaldehyde were tested for
antimicriobial activity against referent strains of: Staphylococcus aureus,
Methicilin resistant S. aureus (MRSA), Escherichia coli; as well as against clinical
isolates of: Staphylococcus pseudintermedius, E. coli, Pseudomonas aeruginosa
and yeast Candida sp. For each etheric oil and active compound minimal inhibitory
concentrations (MIC) are observed by method of broth microdilution. Results of
these investigations have shown that active components of the EO have stronger
antimicrobial effect than complete formulation of essential oils used in the study.
Among tested EOs the most potent was the peppermint etheric oil, while carvacrol
showed the strongest antimicrobial effect among active components of EO.
Interesting finding is that there was almost no difference among MICs between
referent S. aureus and MRSA., Antimikrobna terapija je važno sredstvo u borbi protiv zaraznih bolesti. Značaj
uloge antimikrobnih sredstava u prirodi ostaje neistražen zbog prilagođavanja
patogena različitim oblicima rezistencije. Biljke proizvode sekundarne metabolite,
između ostalog i za prirodnu zaštitu od mikrobne infekcije. Cilj ovog istraživanja
bio je istražiti antimikrobne efekte 5 različitih esencijalnih ulja i 5 glavnih
sastojaka biljnih etarskih ulja na neke od uobičajenih veterinarskih mikrobnih
patogena. Biljna eterična ulja (EO) origana (Origanum vulgare L.), crnog kima
(Nigella sativa L.), sandalovine (Santalum album L.), nane (Mentha balsamea
Wild.) i eukaliptusa (Eucalyptus obliqua L'Hér.) kao i aktivnih komponenti: Dlimonen,
D-α pinen, timol, karvakrol i cinamaldehid testirani su na antimikrobnu
aktivnost protiv referentnih sojeva: Staphylococcus aureus, S. aureus rezistentne na
meticilin (MRSA), Escherichia coli kao i protiv kliničkih izolata: Staphylococcus
pseudintermedius, E. coli, Pseudomonas aeruginosa i kvasca Candida sp. Za svako
eterično ulje i aktivno jedinjenje dobijene su minimalne inhibitorne koncentracije
(MIK) mikrodilucionom metodom u bujonu. Rezultati su pokazali da aktivne
komponente EO imaju jači antimikrobni efekat od EO sa istom odgovarajućom
dominantnom komponentom. Među testiranim EO najmoćnije je bilo eterično ulje
nane, dok je karvakrol pokazao najjači antimikrobni efekat među aktivnim
komponentama EO. Zanimljiv nalaz je da gotovo nije bilo razlike među MIK
između referentne S. aureus i MRSA.",
publisher = "Institute for Animal Husbandry, Belgrade-Zemun, Serbia",
journal = "13th International Symposium: Modern trends in livestock production",
title = "Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study, Aktivnost nekih biljnih eteričnih ulja protiv čestih izolata u veterinarskoj bakteriologiji - pilot studija",
pages = "552-560",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2311"
}
Zdravković, N., Radanović, O., Ninković, M., Savić Radovanović, R., Rajić-Savić, N., Marjanović, Đ.,& Bojkovski, J.. (2021). Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study. in 13th International Symposium: Modern trends in livestock production
Institute for Animal Husbandry, Belgrade-Zemun, Serbia., 552-560.
https://hdl.handle.net/21.15107/rcub_veterinar_2311
Zdravković N, Radanović O, Ninković M, Savić Radovanović R, Rajić-Savić N, Marjanović Đ, Bojkovski J. Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study. in 13th International Symposium: Modern trends in livestock production. 2021;:552-560.
https://hdl.handle.net/21.15107/rcub_veterinar_2311 .
Zdravković, Nemanja, Radanović, Oliver, Ninković, Milan, Savić Radovanović, Radoslava, Rajić-Savić, Nataša, Marjanović, Đorđe, Bojkovski, Jovan, "Activity of some plant essential oils against common isolates in veterinary bacteriology - a pilot study" in 13th International Symposium: Modern trends in livestock production (2021):552-560,
https://hdl.handle.net/21.15107/rcub_veterinar_2311 .

Identification and genetic characterization of porcine circovirus 3 on pig farms in Serbia

Savić, Božidar; Milićević, Vesna; Radanović, Oliver; Zdravković, Nemanja; Stevančević, Ognjen; Kureljušić, Branislav; Nešić, Ksenija

(Springer, 2020)

TY  - JOUR
AU  - Savić, Božidar
AU  - Milićević, Vesna
AU  - Radanović, Oliver
AU  - Zdravković, Nemanja
AU  - Stevančević, Ognjen
AU  - Kureljušić, Branislav
AU  - Nešić, Ksenija
PY  - 2020
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1990
AB  - Backgroud: The presence of PCV3 genome has been detected in pigs affected by different clinical and pathological conditions as well as in healthy animals. Its presence has been reported in many countries of North and South America, Asia and Europe. However, there is no evidence of the presence and genetic characteristics of PCV3 in many European countries and especially the countries of the Balkan Peninsula. Purpose: The major objective of this study was to investigate the presence and obtain further genetic characterization of PCV-3 in the pig populations in Serbia. Methods: To demonstrate the presence of PCV-3 DNA a conventional PCR assay was performed. The samples where no PCR product was observed (n=32), were further tested with a real-time PCR assay. The six PCR samples that were strongly positive for PCV-3 were subjected to amplification and sequencing of their entire cap genes and complete viral genome. Results: We report on the first identification, genetic diversity and potential association in pathogenesis of some systemic and respiratory swine diseases of PCV-3 in Serbia. Conclusion: The results imply that PCV-3 circulates widely in the pig population and has a high similarity with previously reported isolates. Detected PCV-3 can be associated with some swine systemic and respiratory diseases but these associations are strongly influenced by the clinical or pathological condition of the animals. Our findings demonstrate that there are certain PCV-3 loads in pigs suffering from active PRRSV infection, Glässer’s disease, APP pleuropneumonia, pneumonic pasteurellosis and PRDC; however, the significance of this viral load, as well as the mechanism by which PCV-3 may act as a secondary agent in aggravating the severity during co-infections of these pathogens, requires further research.
PB  - Springer
T2  - Archives of Virology
T1  - Identification and genetic characterization of porcine circovirus 3 on pig farms in Serbia
VL  - 165
IS  - 1
SP  - 193
EP  - 199
DO  - 10.1007/s00705-019-04455-y
ER  - 
@article{
author = "Savić, Božidar and Milićević, Vesna and Radanović, Oliver and Zdravković, Nemanja and Stevančević, Ognjen and Kureljušić, Branislav and Nešić, Ksenija",
year = "2020",
abstract = "Backgroud: The presence of PCV3 genome has been detected in pigs affected by different clinical and pathological conditions as well as in healthy animals. Its presence has been reported in many countries of North and South America, Asia and Europe. However, there is no evidence of the presence and genetic characteristics of PCV3 in many European countries and especially the countries of the Balkan Peninsula. Purpose: The major objective of this study was to investigate the presence and obtain further genetic characterization of PCV-3 in the pig populations in Serbia. Methods: To demonstrate the presence of PCV-3 DNA a conventional PCR assay was performed. The samples where no PCR product was observed (n=32), were further tested with a real-time PCR assay. The six PCR samples that were strongly positive for PCV-3 were subjected to amplification and sequencing of their entire cap genes and complete viral genome. Results: We report on the first identification, genetic diversity and potential association in pathogenesis of some systemic and respiratory swine diseases of PCV-3 in Serbia. Conclusion: The results imply that PCV-3 circulates widely in the pig population and has a high similarity with previously reported isolates. Detected PCV-3 can be associated with some swine systemic and respiratory diseases but these associations are strongly influenced by the clinical or pathological condition of the animals. Our findings demonstrate that there are certain PCV-3 loads in pigs suffering from active PRRSV infection, Glässer’s disease, APP pleuropneumonia, pneumonic pasteurellosis and PRDC; however, the significance of this viral load, as well as the mechanism by which PCV-3 may act as a secondary agent in aggravating the severity during co-infections of these pathogens, requires further research.",
publisher = "Springer",
journal = "Archives of Virology",
title = "Identification and genetic characterization of porcine circovirus 3 on pig farms in Serbia",
volume = "165",
number = "1",
pages = "193-199",
doi = "10.1007/s00705-019-04455-y"
}
Savić, B., Milićević, V., Radanović, O., Zdravković, N., Stevančević, O., Kureljušić, B.,& Nešić, K.. (2020). Identification and genetic characterization of porcine circovirus 3 on pig farms in Serbia. in Archives of Virology
Springer., 165(1), 193-199.
https://doi.org/10.1007/s00705-019-04455-y
Savić B, Milićević V, Radanović O, Zdravković N, Stevančević O, Kureljušić B, Nešić K. Identification and genetic characterization of porcine circovirus 3 on pig farms in Serbia. in Archives of Virology. 2020;165(1):193-199.
doi:10.1007/s00705-019-04455-y .
Savić, Božidar, Milićević, Vesna, Radanović, Oliver, Zdravković, Nemanja, Stevančević, Ognjen, Kureljušić, Branislav, Nešić, Ksenija, "Identification and genetic characterization of porcine circovirus 3 on pig farms in Serbia" in Archives of Virology, 165, no. 1 (2020):193-199,
https://doi.org/10.1007/s00705-019-04455-y . .
11
7
8

Evidence of West Nile virus (WNV) circulation in wild birds and WNV RNA negativity in mosquitoes of the Danube Delta Biosphere Reserve, Romania, 2016

Vasić, A.; Oșlobanu, L.E.; Marinov, M.; Crivei, L.A.; Rățoi, I.A.; Aniță, A.; Aniță, D.; Doroșencu, A.; Alexe, V.; Raileanu, Cristian; Simeunović, Predrag; Raileanu, Cristian; Falcuța, E.; Prioteasa, F.L.; Bojkovski, Jovan; Pavlović, I.; Mathis, A.; Tews, B.A.; Savuta, Gheorghe; Veronesi, E.; Silaghi, Cornelia; Cimpan, A.; Ciucă, L.; Cojkić, A.; Drašković, Vladimir; Đurić, M.; Glavinić, Uroš; Ivanescu, M.L.; Kavran, M.; Lupu, A.; Mindru, Raluca; Porea, Daniela; Radanović, Oliver; Ristanić, Marko; Roman, Constantin; Stanišić, Ljubodrag; Zdravković, Nemanja; Vaselek, S.; SCOPES, AMSAR training group

(MDPI AG, 2019)

TY  - JOUR
AU  - Vasić, A.
AU  - Oșlobanu, L.E.
AU  - Marinov, M.
AU  - Crivei, L.A.
AU  - Rățoi, I.A.
AU  - Aniță, A.
AU  - Aniță, D.
AU  - Doroșencu, A.
AU  - Alexe, V.
AU  - Raileanu, Cristian
AU  - Simeunović, Predrag
AU  - Raileanu, Cristian
AU  - Falcuța, E.
AU  - Prioteasa, F.L.
AU  - Bojkovski, Jovan
AU  - Pavlović, I.
AU  - Mathis, A.
AU  - Tews, B.A.
AU  - Savuta, Gheorghe
AU  - Veronesi, E.
AU  - Silaghi, Cornelia
AU  - Cimpan, A.
AU  - Ciucă, L.
AU  - Cojkić, A.
AU  - Drašković, Vladimir
AU  - Đurić, M.
AU  - Glavinić, Uroš
AU  - Ivanescu, M.L.
AU  - Kavran, M.
AU  - Lupu, A.
AU  - Mindru, Raluca
AU  - Porea, Daniela
AU  - Radanović, Oliver
AU  - Ristanić, Marko
AU  - Roman, Constantin
AU  - Stanišić, Ljubodrag
AU  - Zdravković, Nemanja
AU  - Vaselek, S.
AU  - SCOPES, AMSAR training group
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1720
AB  - West Nile virus (WNV) is a zoonotic flavivirus whose transmission cycle in nature includes wild birds as amplifying hosts and ornithophilic mosquito vectors. Bridge vectors can transmit WNV to mammal species potentially causing West Nile Fever. Wild bird migration is a mode of WNV introduction into new areas. The Danube Delta Biosphere Reserve (DDBR) is a major stopover of wild birds migrating between Europe and Africa. The aim of this study was to investigate the presence of WNV in the DDBR during the 2016 transmission season in wild birds and mosquitoes. Blood from 68 wild birds (nine different species) trapped at four different locations was analyzed by competitive ELISA and Virus Neutralization Test (VNT), revealing positive results in 8/68 (11.8%) of the wild birds by ELISA of which six samples (three from juvenile birds) were confirmed seropositive by VNT. Mosquitoes (n = 6523, 5 genera) were trapped with CDC Mini Light traps at two locations and in one location resting mosquitoes were caught. The presence of WNV RNA was tested in 134 pools by reverse transcription quantitative PCR (RT-qPCR). None of the pools was positive for WNV-specific RNA. Based on the obtained results, WNV was circulating in the DDBR during 2016.
PB  - MDPI AG
T2  - Tropical Medicine and Infectious Disease
T1  - Evidence of West Nile virus (WNV) circulation in wild birds and WNV RNA negativity in mosquitoes of the Danube Delta Biosphere Reserve, Romania, 2016
VL  - 4
IS  - 3
SP  - 116
DO  - 10.3390/tropicalmed4030116
ER  - 
@article{
author = "Vasić, A. and Oșlobanu, L.E. and Marinov, M. and Crivei, L.A. and Rățoi, I.A. and Aniță, A. and Aniță, D. and Doroșencu, A. and Alexe, V. and Raileanu, Cristian and Simeunović, Predrag and Raileanu, Cristian and Falcuța, E. and Prioteasa, F.L. and Bojkovski, Jovan and Pavlović, I. and Mathis, A. and Tews, B.A. and Savuta, Gheorghe and Veronesi, E. and Silaghi, Cornelia and Cimpan, A. and Ciucă, L. and Cojkić, A. and Drašković, Vladimir and Đurić, M. and Glavinić, Uroš and Ivanescu, M.L. and Kavran, M. and Lupu, A. and Mindru, Raluca and Porea, Daniela and Radanović, Oliver and Ristanić, Marko and Roman, Constantin and Stanišić, Ljubodrag and Zdravković, Nemanja and Vaselek, S. and SCOPES, AMSAR training group",
year = "2019",
abstract = "West Nile virus (WNV) is a zoonotic flavivirus whose transmission cycle in nature includes wild birds as amplifying hosts and ornithophilic mosquito vectors. Bridge vectors can transmit WNV to mammal species potentially causing West Nile Fever. Wild bird migration is a mode of WNV introduction into new areas. The Danube Delta Biosphere Reserve (DDBR) is a major stopover of wild birds migrating between Europe and Africa. The aim of this study was to investigate the presence of WNV in the DDBR during the 2016 transmission season in wild birds and mosquitoes. Blood from 68 wild birds (nine different species) trapped at four different locations was analyzed by competitive ELISA and Virus Neutralization Test (VNT), revealing positive results in 8/68 (11.8%) of the wild birds by ELISA of which six samples (three from juvenile birds) were confirmed seropositive by VNT. Mosquitoes (n = 6523, 5 genera) were trapped with CDC Mini Light traps at two locations and in one location resting mosquitoes were caught. The presence of WNV RNA was tested in 134 pools by reverse transcription quantitative PCR (RT-qPCR). None of the pools was positive for WNV-specific RNA. Based on the obtained results, WNV was circulating in the DDBR during 2016.",
publisher = "MDPI AG",
journal = "Tropical Medicine and Infectious Disease",
title = "Evidence of West Nile virus (WNV) circulation in wild birds and WNV RNA negativity in mosquitoes of the Danube Delta Biosphere Reserve, Romania, 2016",
volume = "4",
number = "3",
pages = "116",
doi = "10.3390/tropicalmed4030116"
}
Vasić, A., Oșlobanu, L.E., Marinov, M., Crivei, L.A., Rățoi, I.A., Aniță, A., Aniță, D., Doroșencu, A., Alexe, V., Raileanu, C., Simeunović, P., Raileanu, C., Falcuța, E., Prioteasa, F.L., Bojkovski, J., Pavlović, I., Mathis, A., Tews, B.A., Savuta, G., Veronesi, E., Silaghi, C., Cimpan, A., Ciucă, L., Cojkić, A., Drašković, V., Đurić, M., Glavinić, U., Ivanescu, M.L., Kavran, M., Lupu, A., Mindru, R., Porea, D., Radanović, O., Ristanić, M., Roman, C., Stanišić, L., Zdravković, N., Vaselek, S.,& SCOPES, A. t. g.. (2019). Evidence of West Nile virus (WNV) circulation in wild birds and WNV RNA negativity in mosquitoes of the Danube Delta Biosphere Reserve, Romania, 2016. in Tropical Medicine and Infectious Disease
MDPI AG., 4(3), 116.
https://doi.org/10.3390/tropicalmed4030116
Vasić A, Oșlobanu L, Marinov M, Crivei L, Rățoi I, Aniță A, Aniță D, Doroșencu A, Alexe V, Raileanu C, Simeunović P, Raileanu C, Falcuța E, Prioteasa F, Bojkovski J, Pavlović I, Mathis A, Tews B, Savuta G, Veronesi E, Silaghi C, Cimpan A, Ciucă L, Cojkić A, Drašković V, Đurić M, Glavinić U, Ivanescu M, Kavran M, Lupu A, Mindru R, Porea D, Radanović O, Ristanić M, Roman C, Stanišić L, Zdravković N, Vaselek S, SCOPES ATG. Evidence of West Nile virus (WNV) circulation in wild birds and WNV RNA negativity in mosquitoes of the Danube Delta Biosphere Reserve, Romania, 2016. in Tropical Medicine and Infectious Disease. 2019;4(3):116.
doi:10.3390/tropicalmed4030116 .
Vasić, A., Oșlobanu, L.E., Marinov, M., Crivei, L.A., Rățoi, I.A., Aniță, A., Aniță, D., Doroșencu, A., Alexe, V., Raileanu, Cristian, Simeunović, Predrag, Raileanu, Cristian, Falcuța, E., Prioteasa, F.L., Bojkovski, Jovan, Pavlović, I., Mathis, A., Tews, B.A., Savuta, Gheorghe, Veronesi, E., Silaghi, Cornelia, Cimpan, A., Ciucă, L., Cojkić, A., Drašković, Vladimir, Đurić, M., Glavinić, Uroš, Ivanescu, M.L., Kavran, M., Lupu, A., Mindru, Raluca, Porea, Daniela, Radanović, Oliver, Ristanić, Marko, Roman, Constantin, Stanišić, Ljubodrag, Zdravković, Nemanja, Vaselek, S., SCOPES, AMSAR training group, "Evidence of West Nile virus (WNV) circulation in wild birds and WNV RNA negativity in mosquitoes of the Danube Delta Biosphere Reserve, Romania, 2016" in Tropical Medicine and Infectious Disease, 4, no. 3 (2019):116,
https://doi.org/10.3390/tropicalmed4030116 . .
3
8
8

Species diversity, host preference and arbovirus detection of Culicoides (Diptera: Ceratopogonidae) in south-eastern Serbia

Vasić, Ana; Zdravković, Nemanja; Anita, Dragos; Bojkovski, Jovan; Marinov, Mihai; Mathis, Alexander; Niculaua, Marius; Oslobanu, Elena Luanda; Pavlović, Ivan; Petrić, Dusan; Pflueger, Valentin; Pudar, Dubravka; Savuta, Gheorghe; Simeunović, Predrag; Veronesi, Eva; Silaghi, Cornelia; Anita, Adriana; Anton, Ioana Alexandra; Cimpan, Andrei; Ciuca, Lavinia; Crivei, Luciana; Cojkić, Aleksandar; Davitkov, Darko; Drašković, Vladimir; Gajić, Bojan; Glavinić, Uroš; Ivanescu, Maria-Larisa; Kavran, Mihaela; Lupu, Andrei-Cristian; Mindru, Raluca; Porea, Daniela; Prodanović, Radiša; Radanović, Oliver; Raileanu, Cristian; Raileanu, Stefan; Ristanić, Marko; Roman, Constantin; Stanišić, Ljubodrag; Vaselek, Slavica; Đurić, Miloje

(BMC, London, 2019)

TY  - JOUR
AU  - Vasić, Ana
AU  - Zdravković, Nemanja
AU  - Anita, Dragos
AU  - Bojkovski, Jovan
AU  - Marinov, Mihai
AU  - Mathis, Alexander
AU  - Niculaua, Marius
AU  - Oslobanu, Elena Luanda
AU  - Pavlović, Ivan
AU  - Petrić, Dusan
AU  - Pflueger, Valentin
AU  - Pudar, Dubravka
AU  - Savuta, Gheorghe
AU  - Simeunović, Predrag
AU  - Veronesi, Eva
AU  - Silaghi, Cornelia
AU  - Anita, Adriana
AU  - Anton, Ioana Alexandra
AU  - Cimpan, Andrei
AU  - Ciuca, Lavinia
AU  - Crivei, Luciana
AU  - Cojkić, Aleksandar
AU  - Davitkov, Darko
AU  - Drašković, Vladimir
AU  - Gajić, Bojan
AU  - Glavinić, Uroš
AU  - Ivanescu, Maria-Larisa
AU  - Kavran, Mihaela
AU  - Lupu, Andrei-Cristian
AU  - Mindru, Raluca
AU  - Porea, Daniela
AU  - Prodanović, Radiša
AU  - Radanović, Oliver
AU  - Raileanu, Cristian
AU  - Raileanu, Stefan
AU  - Ristanić, Marko
AU  - Roman, Constantin
AU  - Stanišić, Ljubodrag
AU  - Vaselek, Slavica
AU  - Đurić, Miloje
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1740
AB  - BackgroundCulicoides (Diptera: Ceratopogonidae) is a genus of small biting midges (also known as no-see ums) that currently includes 1368 described species. They are proven or suspected vectors for important pathogens affecting animals such as bluetongue virus (BTV) and Schmallenberg virus (SBV). Currently little information is available on the species of Culicoides present in Serbia. Thus, the aim of this study was to examine species diversity, host preference and the presence of BTV and SBV RNA in Culicoides from the Stara Planina Nature Park in south-eastern Serbia.ResultsIn total 19,887 individual Culicoides were collected during three nights of trapping at two farm sites and pooled into six groups (Obsoletus group, Pulicaris group, Others group and further each group according to the blood-feeding status to freshly engorged and non-engorged). Species identification was done on subsamples of 592 individual Culicoides specimens by morphological and molecular methods (MALDI-TOF mass spectrometry and PCR/sequencing). At least 22 Culicoides species were detected. Four animal species (cow, sheep, goat and common blackbird) as well as humans were identified as hosts of Culicoides biting midges. The screening of 8291 Culicoides specimens in 99 pools for the presence of BTV and SBV RNA by reverse-transcription quantitative PCR were negative.ConclusionsThe biodiversity of Culicoides species in the natural reserve Stara Planina was high with at least 22 species present. The presence of C. imicola Kieffer was not recorded in this area. Culicoides showed opportunistic feeding behaviour as determined by host preference. The absence of SBV and BTV viral RNA correlates with the absence of clinical disease in the field during the time of sampling. These data are the direct outcome of a training programme within the Institutional Partnership Project AMSAR: Arbovirus monitoring, research and surveillance-capacity building on mosquitoes and biting midges funded by the programme SCOPES of the Swiss National Science Foundation.
PB  - BMC, London
T2  - Parasites & Vectors
T1  - Species diversity, host preference and arbovirus detection of Culicoides (Diptera: Ceratopogonidae) in south-eastern Serbia
VL  - 12
SP  - 61
DO  - 10.1186/s13071-019-3292-3
ER  - 
@article{
author = "Vasić, Ana and Zdravković, Nemanja and Anita, Dragos and Bojkovski, Jovan and Marinov, Mihai and Mathis, Alexander and Niculaua, Marius and Oslobanu, Elena Luanda and Pavlović, Ivan and Petrić, Dusan and Pflueger, Valentin and Pudar, Dubravka and Savuta, Gheorghe and Simeunović, Predrag and Veronesi, Eva and Silaghi, Cornelia and Anita, Adriana and Anton, Ioana Alexandra and Cimpan, Andrei and Ciuca, Lavinia and Crivei, Luciana and Cojkić, Aleksandar and Davitkov, Darko and Drašković, Vladimir and Gajić, Bojan and Glavinić, Uroš and Ivanescu, Maria-Larisa and Kavran, Mihaela and Lupu, Andrei-Cristian and Mindru, Raluca and Porea, Daniela and Prodanović, Radiša and Radanović, Oliver and Raileanu, Cristian and Raileanu, Stefan and Ristanić, Marko and Roman, Constantin and Stanišić, Ljubodrag and Vaselek, Slavica and Đurić, Miloje",
year = "2019",
abstract = "BackgroundCulicoides (Diptera: Ceratopogonidae) is a genus of small biting midges (also known as no-see ums) that currently includes 1368 described species. They are proven or suspected vectors for important pathogens affecting animals such as bluetongue virus (BTV) and Schmallenberg virus (SBV). Currently little information is available on the species of Culicoides present in Serbia. Thus, the aim of this study was to examine species diversity, host preference and the presence of BTV and SBV RNA in Culicoides from the Stara Planina Nature Park in south-eastern Serbia.ResultsIn total 19,887 individual Culicoides were collected during three nights of trapping at two farm sites and pooled into six groups (Obsoletus group, Pulicaris group, Others group and further each group according to the blood-feeding status to freshly engorged and non-engorged). Species identification was done on subsamples of 592 individual Culicoides specimens by morphological and molecular methods (MALDI-TOF mass spectrometry and PCR/sequencing). At least 22 Culicoides species were detected. Four animal species (cow, sheep, goat and common blackbird) as well as humans were identified as hosts of Culicoides biting midges. The screening of 8291 Culicoides specimens in 99 pools for the presence of BTV and SBV RNA by reverse-transcription quantitative PCR were negative.ConclusionsThe biodiversity of Culicoides species in the natural reserve Stara Planina was high with at least 22 species present. The presence of C. imicola Kieffer was not recorded in this area. Culicoides showed opportunistic feeding behaviour as determined by host preference. The absence of SBV and BTV viral RNA correlates with the absence of clinical disease in the field during the time of sampling. These data are the direct outcome of a training programme within the Institutional Partnership Project AMSAR: Arbovirus monitoring, research and surveillance-capacity building on mosquitoes and biting midges funded by the programme SCOPES of the Swiss National Science Foundation.",
publisher = "BMC, London",
journal = "Parasites & Vectors",
title = "Species diversity, host preference and arbovirus detection of Culicoides (Diptera: Ceratopogonidae) in south-eastern Serbia",
volume = "12",
pages = "61",
doi = "10.1186/s13071-019-3292-3"
}
Vasić, A., Zdravković, N., Anita, D., Bojkovski, J., Marinov, M., Mathis, A., Niculaua, M., Oslobanu, E. L., Pavlović, I., Petrić, D., Pflueger, V., Pudar, D., Savuta, G., Simeunović, P., Veronesi, E., Silaghi, C., Anita, A., Anton, I. A., Cimpan, A., Ciuca, L., Crivei, L., Cojkić, A., Davitkov, D., Drašković, V., Gajić, B., Glavinić, U., Ivanescu, M., Kavran, M., Lupu, A., Mindru, R., Porea, D., Prodanović, R., Radanović, O., Raileanu, C., Raileanu, S., Ristanić, M., Roman, C., Stanišić, L., Vaselek, S.,& Đurić, M.. (2019). Species diversity, host preference and arbovirus detection of Culicoides (Diptera: Ceratopogonidae) in south-eastern Serbia. in Parasites & Vectors
BMC, London., 12, 61.
https://doi.org/10.1186/s13071-019-3292-3
Vasić A, Zdravković N, Anita D, Bojkovski J, Marinov M, Mathis A, Niculaua M, Oslobanu EL, Pavlović I, Petrić D, Pflueger V, Pudar D, Savuta G, Simeunović P, Veronesi E, Silaghi C, Anita A, Anton IA, Cimpan A, Ciuca L, Crivei L, Cojkić A, Davitkov D, Drašković V, Gajić B, Glavinić U, Ivanescu M, Kavran M, Lupu A, Mindru R, Porea D, Prodanović R, Radanović O, Raileanu C, Raileanu S, Ristanić M, Roman C, Stanišić L, Vaselek S, Đurić M. Species diversity, host preference and arbovirus detection of Culicoides (Diptera: Ceratopogonidae) in south-eastern Serbia. in Parasites & Vectors. 2019;12:61.
doi:10.1186/s13071-019-3292-3 .
Vasić, Ana, Zdravković, Nemanja, Anita, Dragos, Bojkovski, Jovan, Marinov, Mihai, Mathis, Alexander, Niculaua, Marius, Oslobanu, Elena Luanda, Pavlović, Ivan, Petrić, Dusan, Pflueger, Valentin, Pudar, Dubravka, Savuta, Gheorghe, Simeunović, Predrag, Veronesi, Eva, Silaghi, Cornelia, Anita, Adriana, Anton, Ioana Alexandra, Cimpan, Andrei, Ciuca, Lavinia, Crivei, Luciana, Cojkić, Aleksandar, Davitkov, Darko, Drašković, Vladimir, Gajić, Bojan, Glavinić, Uroš, Ivanescu, Maria-Larisa, Kavran, Mihaela, Lupu, Andrei-Cristian, Mindru, Raluca, Porea, Daniela, Prodanović, Radiša, Radanović, Oliver, Raileanu, Cristian, Raileanu, Stefan, Ristanić, Marko, Roman, Constantin, Stanišić, Ljubodrag, Vaselek, Slavica, Đurić, Miloje, "Species diversity, host preference and arbovirus detection of Culicoides (Diptera: Ceratopogonidae) in south-eastern Serbia" in Parasites & Vectors, 12 (2019):61,
https://doi.org/10.1186/s13071-019-3292-3 . .
10
11
5
11

Comparative pathomorphological, mycological and molecular examination of turkey poults with different immunological status experimentally infected with aspergillus fumigatus

Jezdimirović, Nemanja; Kureljušić, Branislav; Ivetić, Vojin; Krnjaić, Dejan; Radanović, Oliver; Žutić, Jadranka; Spalević, Ljiljana; Jovanović, Milijan

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2019)

TY  - JOUR
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Branislav
AU  - Ivetić, Vojin
AU  - Krnjaić, Dejan
AU  - Radanović, Oliver
AU  - Žutić, Jadranka
AU  - Spalević, Ljiljana
AU  - Jovanović, Milijan
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1748
AB  - The aim of this study was to determine the pathological, mycological and molecular findings in turkey poults with different immunological status experimentally infected with Aspergillus fumigatus. The investigation was carried out 1, 3, 7, 14 and 21 days after intratracheal inoculation of 5.056x10(7) spores of A. fumigatus to 14-day-old turkey poults in group G-1, as well as to turkey poults in group G-2 which were treated prior to infection with dexamethasone. A. fumigatus was isolated on day 1 p.i. in both groups, but the number of positive samples was bigger in group G-1. A. fumigatus was isolated from the respiratory organs of group G-1as early as on day 1 and 3 p.i. in 4 out of 12 examined specimens (33%). On day 7 p.i. A. fumigatus was possible to isolate from the respiratory organs of 50% of infected birds, on day 14 in 83.33% and on day 21 p.i. A. fumigatus was isolated in 6 out of 6 sacrificed turkey poults (100%). In dexamethasone-treated group A. fumigatus isolates from the respiratory organs on day 1 and 3 p.i. were same as in group G-1, whereas on days 7 and 14 p.i. the number of turkey poults positive to A. fumigatus increased in comparison with the untreated G-1 group. The histopathological lesions in turkey poults treated with dexamethasone developed earlier, were more intensive and extensive. The mycological and nested PCR results revealed a higher number of samples positive for the presence of A. fumigatus DNA in the group G-2, pretreated with dexamethasone.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Comparative pathomorphological, mycological and molecular examination of turkey poults with different immunological status experimentally infected with aspergillus fumigatus
VL  - 69
IS  - 2
SP  - 201
EP  - 217
DO  - 10.2478/acve-2019-0016
ER  - 
@article{
author = "Jezdimirović, Nemanja and Kureljušić, Branislav and Ivetić, Vojin and Krnjaić, Dejan and Radanović, Oliver and Žutić, Jadranka and Spalević, Ljiljana and Jovanović, Milijan",
year = "2019",
abstract = "The aim of this study was to determine the pathological, mycological and molecular findings in turkey poults with different immunological status experimentally infected with Aspergillus fumigatus. The investigation was carried out 1, 3, 7, 14 and 21 days after intratracheal inoculation of 5.056x10(7) spores of A. fumigatus to 14-day-old turkey poults in group G-1, as well as to turkey poults in group G-2 which were treated prior to infection with dexamethasone. A. fumigatus was isolated on day 1 p.i. in both groups, but the number of positive samples was bigger in group G-1. A. fumigatus was isolated from the respiratory organs of group G-1as early as on day 1 and 3 p.i. in 4 out of 12 examined specimens (33%). On day 7 p.i. A. fumigatus was possible to isolate from the respiratory organs of 50% of infected birds, on day 14 in 83.33% and on day 21 p.i. A. fumigatus was isolated in 6 out of 6 sacrificed turkey poults (100%). In dexamethasone-treated group A. fumigatus isolates from the respiratory organs on day 1 and 3 p.i. were same as in group G-1, whereas on days 7 and 14 p.i. the number of turkey poults positive to A. fumigatus increased in comparison with the untreated G-1 group. The histopathological lesions in turkey poults treated with dexamethasone developed earlier, were more intensive and extensive. The mycological and nested PCR results revealed a higher number of samples positive for the presence of A. fumigatus DNA in the group G-2, pretreated with dexamethasone.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Comparative pathomorphological, mycological and molecular examination of turkey poults with different immunological status experimentally infected with aspergillus fumigatus",
volume = "69",
number = "2",
pages = "201-217",
doi = "10.2478/acve-2019-0016"
}
Jezdimirović, N., Kureljušić, B., Ivetić, V., Krnjaić, D., Radanović, O., Žutić, J., Spalević, L.,& Jovanović, M.. (2019). Comparative pathomorphological, mycological and molecular examination of turkey poults with different immunological status experimentally infected with aspergillus fumigatus. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 69(2), 201-217.
https://doi.org/10.2478/acve-2019-0016
Jezdimirović N, Kureljušić B, Ivetić V, Krnjaić D, Radanović O, Žutić J, Spalević L, Jovanović M. Comparative pathomorphological, mycological and molecular examination of turkey poults with different immunological status experimentally infected with aspergillus fumigatus. in Acta Veterinaria-Beograd. 2019;69(2):201-217.
doi:10.2478/acve-2019-0016 .
Jezdimirović, Nemanja, Kureljušić, Branislav, Ivetić, Vojin, Krnjaić, Dejan, Radanović, Oliver, Žutić, Jadranka, Spalević, Ljiljana, Jovanović, Milijan, "Comparative pathomorphological, mycological and molecular examination of turkey poults with different immunological status experimentally infected with aspergillus fumigatus" in Acta Veterinaria-Beograd, 69, no. 2 (2019):201-217,
https://doi.org/10.2478/acve-2019-0016 . .
1

Occurrence of neonatal diarrhea in calves with iron-deficiency anemia

Prodanović, Radiša; Nedić, Sreten; Radanović, Oliver; Milićević, Vesna; Vujanac, Ivan; Bojkovski, Jovan; Kureljušić, Branislav; Arsić, Sveta; Jovanović, Ljubomir; Kirovski, Danijela

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2019)

TY  - JOUR
AU  - Prodanović, Radiša
AU  - Nedić, Sreten
AU  - Radanović, Oliver
AU  - Milićević, Vesna
AU  - Vujanac, Ivan
AU  - Bojkovski, Jovan
AU  - Kureljušić, Branislav
AU  - Arsić, Sveta
AU  - Jovanović, Ljubomir
AU  - Kirovski, Danijela
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1705
AB  - Introduction. Neonatal calves are often deficient in iron. Accumulating evidence indicates that iron status is associated with disease pathologies including diarrhea. Our objective was to examine the association between iron status and gut function in neonatal calves with and without a history of calf diarrhea. Materials and Methods. Calves were divided into two groups based on their history of diarrhea; the first group were diarrheic calves (n=6) and the second group were non-diarrheic healthy calves (n=6). Blood samples (n=12) were collected at day 12 of age and erythrogram determination and measurements of serum iron and total iron binding capacity were performed. Hematological values were measured using an automatic analyzer, and biochemical properties were determined spectrophotometrically. Fecal samples were obtained from all calves and pH measured using semi quantitative test strips as well as being examined by bacterial cultivation for enterotoxigenic Escherichia coli, Salmonella spp. and Clostridium perfringens, by RT-PCR for the presence of bovine rotavirus, bovine coronavirus and bovine viral diarrhea virus, and by microscopy for the presence of Cryptosporidium parvum. Results and Conclusions. There were significant iron-related changes for most hematological indices in diarrheic calves; and iron (Fe) deficiency and microcytic, hypochromic anemia were diagnosed. The pH of the feces was significantly higher in diarrheic calves than in the non-diarrheic healthy group (P lt 0.01). All fecal samples were negative for the analyzed enteric pathogens. According to the results obtained, calves experiencing iron deficiency anemia exhibit changes in gut function leading to diarrhea as compared with a matched group of healthy calves.
AB  - Uvod. Neonatalna telad su često deficitarna u gvožđu. Brojni podaci ukazuju na povezanost nedostatka gvožđa sa različitim patološkim stanjima, uključujući i pojavu dijareje. Cilj rada bio je da se ispita povezanost statusa gvožđa i promena u funkciji digestivnog trakta novorođene teladi sa i bez znakova dijareje. Materijal i Metode. Telad su podeljena u dve grupe na osnovu pojave dijareje; prva grupa (n=6) telad sa dijarejom i druga grupa (n=6) klinički zdrava telad bez znakova dijareje. Uzorci krvi su uzeti od sve teladi 12. dana života i određeni su parametri crvene krvne slike, sadržaj serumskog gvožđa i ukupni kapacitet vezivanja gvožđa. Parametri crvene krvne slike određeni su automatskim hematološkim analajzerom, dok su biohemijski parametri određeni spektrofotometrijski. Uzorci fecesa uzeti su od sve teladi i izmerena je pH vrednost semikvantitativno pomoću test tračica. Bakteriološkim pregledom uzorci fecesa su ispitani na prisustvo enterotoksogenih Escherichia coli, Salmonella spp. i Clostridium perfringens vrsta; RT-PCR metodom ispitani su na prisustvo goveđeg rotavirusa, coronavirusa i virusa goveđe virusne dijareje, dok su mikroskopski pregledani na prisustvo Cryptosporidium parvum. Rezultati i zaključak. Promene u koncentraciji gvožđa dovele su do pojave značajnih promena u hematološkim indeksima teladi sa dijarejom i pojavi mikrocitne hipohromne anemije. Vrednost pH fecesa je bila značajno veća kod teladi sa dijarejom u odnosu na zdravu telad. Svi uzorci fecesa bili su negativni na ispitivane enteropatogene uzročnike. U poređenju sa zdravom teladi, pretpostavka je da kod teladi sa anemijom koja je uzrokovana deficitom gvožđa nastaju promene u funkciji digestivnog trakta koje dovode do pojave dijareje.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Occurrence of neonatal diarrhea in calves with iron-deficiency anemia
T1  - Neonatalna dijareja kod teladi sa anemijom usled nedostatka gvožđa
VL  - 73
IS  - 1
SP  - 1
EP  - 9
DO  - 10.2298/VETGL181210011P
ER  - 
@article{
author = "Prodanović, Radiša and Nedić, Sreten and Radanović, Oliver and Milićević, Vesna and Vujanac, Ivan and Bojkovski, Jovan and Kureljušić, Branislav and Arsić, Sveta and Jovanović, Ljubomir and Kirovski, Danijela",
year = "2019",
abstract = "Introduction. Neonatal calves are often deficient in iron. Accumulating evidence indicates that iron status is associated with disease pathologies including diarrhea. Our objective was to examine the association between iron status and gut function in neonatal calves with and without a history of calf diarrhea. Materials and Methods. Calves were divided into two groups based on their history of diarrhea; the first group were diarrheic calves (n=6) and the second group were non-diarrheic healthy calves (n=6). Blood samples (n=12) were collected at day 12 of age and erythrogram determination and measurements of serum iron and total iron binding capacity were performed. Hematological values were measured using an automatic analyzer, and biochemical properties were determined spectrophotometrically. Fecal samples were obtained from all calves and pH measured using semi quantitative test strips as well as being examined by bacterial cultivation for enterotoxigenic Escherichia coli, Salmonella spp. and Clostridium perfringens, by RT-PCR for the presence of bovine rotavirus, bovine coronavirus and bovine viral diarrhea virus, and by microscopy for the presence of Cryptosporidium parvum. Results and Conclusions. There were significant iron-related changes for most hematological indices in diarrheic calves; and iron (Fe) deficiency and microcytic, hypochromic anemia were diagnosed. The pH of the feces was significantly higher in diarrheic calves than in the non-diarrheic healthy group (P lt 0.01). All fecal samples were negative for the analyzed enteric pathogens. According to the results obtained, calves experiencing iron deficiency anemia exhibit changes in gut function leading to diarrhea as compared with a matched group of healthy calves., Uvod. Neonatalna telad su često deficitarna u gvožđu. Brojni podaci ukazuju na povezanost nedostatka gvožđa sa različitim patološkim stanjima, uključujući i pojavu dijareje. Cilj rada bio je da se ispita povezanost statusa gvožđa i promena u funkciji digestivnog trakta novorođene teladi sa i bez znakova dijareje. Materijal i Metode. Telad su podeljena u dve grupe na osnovu pojave dijareje; prva grupa (n=6) telad sa dijarejom i druga grupa (n=6) klinički zdrava telad bez znakova dijareje. Uzorci krvi su uzeti od sve teladi 12. dana života i određeni su parametri crvene krvne slike, sadržaj serumskog gvožđa i ukupni kapacitet vezivanja gvožđa. Parametri crvene krvne slike određeni su automatskim hematološkim analajzerom, dok su biohemijski parametri određeni spektrofotometrijski. Uzorci fecesa uzeti su od sve teladi i izmerena je pH vrednost semikvantitativno pomoću test tračica. Bakteriološkim pregledom uzorci fecesa su ispitani na prisustvo enterotoksogenih Escherichia coli, Salmonella spp. i Clostridium perfringens vrsta; RT-PCR metodom ispitani su na prisustvo goveđeg rotavirusa, coronavirusa i virusa goveđe virusne dijareje, dok su mikroskopski pregledani na prisustvo Cryptosporidium parvum. Rezultati i zaključak. Promene u koncentraciji gvožđa dovele su do pojave značajnih promena u hematološkim indeksima teladi sa dijarejom i pojavi mikrocitne hipohromne anemije. Vrednost pH fecesa je bila značajno veća kod teladi sa dijarejom u odnosu na zdravu telad. Svi uzorci fecesa bili su negativni na ispitivane enteropatogene uzročnike. U poređenju sa zdravom teladi, pretpostavka je da kod teladi sa anemijom koja je uzrokovana deficitom gvožđa nastaju promene u funkciji digestivnog trakta koje dovode do pojave dijareje.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Occurrence of neonatal diarrhea in calves with iron-deficiency anemia, Neonatalna dijareja kod teladi sa anemijom usled nedostatka gvožđa",
volume = "73",
number = "1",
pages = "1-9",
doi = "10.2298/VETGL181210011P"
}
Prodanović, R., Nedić, S., Radanović, O., Milićević, V., Vujanac, I., Bojkovski, J., Kureljušić, B., Arsić, S., Jovanović, L.,& Kirovski, D.. (2019). Occurrence of neonatal diarrhea in calves with iron-deficiency anemia. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 73(1), 1-9.
https://doi.org/10.2298/VETGL181210011P
Prodanović R, Nedić S, Radanović O, Milićević V, Vujanac I, Bojkovski J, Kureljušić B, Arsić S, Jovanović L, Kirovski D. Occurrence of neonatal diarrhea in calves with iron-deficiency anemia. in Veterinarski Glasnik. 2019;73(1):1-9.
doi:10.2298/VETGL181210011P .
Prodanović, Radiša, Nedić, Sreten, Radanović, Oliver, Milićević, Vesna, Vujanac, Ivan, Bojkovski, Jovan, Kureljušić, Branislav, Arsić, Sveta, Jovanović, Ljubomir, Kirovski, Danijela, "Occurrence of neonatal diarrhea in calves with iron-deficiency anemia" in Veterinarski Glasnik, 73, no. 1 (2019):1-9,
https://doi.org/10.2298/VETGL181210011P . .
4

Antibiogram u maloj veterinarskoj praksi

Zdravković, Nemanja; Radanović, Oliver; Savić Radovanović, Radoslava; Žutić, Jadranka

(Banja Luka : Veterinarska komora Republike Srpske, 2019)

TY  - CONF
AU  - Zdravković, Nemanja
AU  - Radanović, Oliver
AU  - Savić Radovanović, Radoslava
AU  - Žutić, Jadranka
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2886
AB  - Проналазак антимикробних лекова сврстава се у десет највећих подухвата
људског рода XX века. На тему лечења инфекција интересовање за одабир
адекватних активних супстанци за спровођење терапије не јењава од овог
историјског почетка, а нажалост, врло брзо након увођења нових препарата
описивана је и резистенција према истим. Заправо, интересовање за
сазнањима и распрострањеношћу резистентних бактерија је повећано
увођењем система једног здравља и организованог надзора на осетљивост и
резистенцију према антимимикробним лековима. Адекватна примена лечења
и одабира лекова у терапији почиње од тумачења антибиограма.
Антибиограм представља профил антимикробне осетљивости одређеног
изолата, на основу кога се у сваком појединачном случају, врши избор
антибиотика за терапирање. Избор антибиотика за оређени изолат најчешће је
приказан у стандардима за антимикробну терапију. Најпознатији стандари
проистичу из великих комитета као што су Европски (EUCAST) или Амерички
(CLSI) а постоје и други, национални стандарди одређених држава (нпр.
Француска или Велика Британија). На основу резултата већег броја
истраживања долази се до тога који антибиотици се у датом случају могу
проценити као повољан а који као неповољан избор на основу изолата и
патолошког материјала достављеног на анализу.
Најчешће грешке при емпиријском лечењу инфекција најчешће леже у
примени неадекватног лека који не делује на узрочника инфекције или делује
незадовољавајуће. Из овог разлога је потребно скренути пажњу на адекватно
тумачење антибиограма.
AB  - The finding of antimicrobials is ranked among the ten greatest achievements of
the human race of the 20th century. Since historical beginning, the interest in
selecting adequate active substances for the implementation of infection therapy
and unfortunately, very soon after the introduction of new principles, the
resistance to them was described. In fact, the interest in the knowledge and the
prevalence of resistant bacteria has been increased by the introduction of a OneHealth system and the organized monitoring of susceptibility and resistance of
bacteria toward antimicrobial drugs. Adequate application of treatment and
selection of drugs in therapy begins with the interpretation of antibiotibigram.
Antibiogram is the profile of the antimicrobial sensitivity of a particular isolate,
based on in each individual case, antibiotic therapy is chosen. The selection of
antibiotic for particular isolate is most often shown in the standards for
antimicrobial therapy. The most well-known standards come from large
committees such as European (EUCAST) or American (CLSI), and there are other,
national standards of certain countries (e.g. France or Great Britain). Based on the
results of a large number of studies, it comes to what antibiotics can be
administered in the given case and which are an unfavorable choice based on
isolates and pathological material submitted for analysis.
The most common mistakes in the empirical treatment of infections are most
often found in the use of an inadequate drug that does not act on the cause of the
infection or its action is unsatisfactory. For this reason, it is necessary to pay
attention to the adequate interpretation of the antibiogram.
PB  - Banja Luka : Veterinarska komora Republike Srpske
C3  - 24. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), međunarodni naučni skup, Bijeljina, 12-15. jun 2019.
T1  - Antibiogram u maloj veterinarskoj praksi
T1  - Antibiogram in small veterinary practice
SP  - 243
EP  - 244
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2886
ER  - 
@conference{
author = "Zdravković, Nemanja and Radanović, Oliver and Savić Radovanović, Radoslava and Žutić, Jadranka",
year = "2019",
abstract = "Проналазак антимикробних лекова сврстава се у десет највећих подухвата
људског рода XX века. На тему лечења инфекција интересовање за одабир
адекватних активних супстанци за спровођење терапије не јењава од овог
историјског почетка, а нажалост, врло брзо након увођења нових препарата
описивана је и резистенција према истим. Заправо, интересовање за
сазнањима и распрострањеношћу резистентних бактерија је повећано
увођењем система једног здравља и организованог надзора на осетљивост и
резистенцију према антимимикробним лековима. Адекватна примена лечења
и одабира лекова у терапији почиње од тумачења антибиограма.
Антибиограм представља профил антимикробне осетљивости одређеног
изолата, на основу кога се у сваком појединачном случају, врши избор
антибиотика за терапирање. Избор антибиотика за оређени изолат најчешће је
приказан у стандардима за антимикробну терапију. Најпознатији стандари
проистичу из великих комитета као што су Европски (EUCAST) или Амерички
(CLSI) а постоје и други, национални стандарди одређених држава (нпр.
Француска или Велика Британија). На основу резултата већег броја
истраживања долази се до тога који антибиотици се у датом случају могу
проценити као повољан а који као неповољан избор на основу изолата и
патолошког материјала достављеног на анализу.
Најчешће грешке при емпиријском лечењу инфекција најчешће леже у
примени неадекватног лека који не делује на узрочника инфекције или делује
незадовољавајуће. Из овог разлога је потребно скренути пажњу на адекватно
тумачење антибиограма., The finding of antimicrobials is ranked among the ten greatest achievements of
the human race of the 20th century. Since historical beginning, the interest in
selecting adequate active substances for the implementation of infection therapy
and unfortunately, very soon after the introduction of new principles, the
resistance to them was described. In fact, the interest in the knowledge and the
prevalence of resistant bacteria has been increased by the introduction of a OneHealth system and the organized monitoring of susceptibility and resistance of
bacteria toward antimicrobial drugs. Adequate application of treatment and
selection of drugs in therapy begins with the interpretation of antibiotibigram.
Antibiogram is the profile of the antimicrobial sensitivity of a particular isolate,
based on in each individual case, antibiotic therapy is chosen. The selection of
antibiotic for particular isolate is most often shown in the standards for
antimicrobial therapy. The most well-known standards come from large
committees such as European (EUCAST) or American (CLSI), and there are other,
national standards of certain countries (e.g. France or Great Britain). Based on the
results of a large number of studies, it comes to what antibiotics can be
administered in the given case and which are an unfavorable choice based on
isolates and pathological material submitted for analysis.
The most common mistakes in the empirical treatment of infections are most
often found in the use of an inadequate drug that does not act on the cause of the
infection or its action is unsatisfactory. For this reason, it is necessary to pay
attention to the adequate interpretation of the antibiogram.",
publisher = "Banja Luka : Veterinarska komora Republike Srpske",
journal = "24. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), međunarodni naučni skup, Bijeljina, 12-15. jun 2019.",
title = "Antibiogram u maloj veterinarskoj praksi, Antibiogram in small veterinary practice",
pages = "243-244",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2886"
}
Zdravković, N., Radanović, O., Savić Radovanović, R.,& Žutić, J.. (2019). Antibiogram u maloj veterinarskoj praksi. in 24. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), međunarodni naučni skup, Bijeljina, 12-15. jun 2019.
Banja Luka : Veterinarska komora Republike Srpske., 243-244.
https://hdl.handle.net/21.15107/rcub_veterinar_2886
Zdravković N, Radanović O, Savić Radovanović R, Žutić J. Antibiogram u maloj veterinarskoj praksi. in 24. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), međunarodni naučni skup, Bijeljina, 12-15. jun 2019.. 2019;:243-244.
https://hdl.handle.net/21.15107/rcub_veterinar_2886 .
Zdravković, Nemanja, Radanović, Oliver, Savić Radovanović, Radoslava, Žutić, Jadranka, "Antibiogram u maloj veterinarskoj praksi" in 24. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), međunarodni naučni skup, Bijeljina, 12-15. jun 2019. (2019):243-244,
https://hdl.handle.net/21.15107/rcub_veterinar_2886 .

Seasonal dynamics of the presence of culicoides spp. in Serbia in the period 2015-2016

Pavlović, Ivan; Veljović, Ljubiša; Milićević, Vesna; Maksimović-Zorić, Jelena; Stanojević, Slobodan; Radanović, Oliver; Đurić, Boban; Plavšić, Budimir; Vasić, Ana

(Scientific Veterinary Institute “Novi Sad”, Novi Sad, 2019)

TY  - JOUR
AU  - Pavlović, Ivan
AU  - Veljović, Ljubiša
AU  - Milićević, Vesna
AU  - Maksimović-Zorić, Jelena
AU  - Stanojević, Slobodan
AU  - Radanović, Oliver
AU  - Đurić, Boban
AU  - Plavšić, Budimir
AU  - Vasić, Ana
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1958
AB  - Genus Culicoides spp. includes small insects 0.5-2 mm in length, usually grey or black and at first glance very similar to mosquitoes. They are strictly hematophagous, feeding by attacking hosts outdoors and indoors (although they are less susceptible to the stationing like Aedes mosquitoes do). The sting is very painful at the injection site and often followed by hypersensibilisation with the consequent formation of allergic dermatitis. In addition, the insects carry and transmit a multitude of diseases, often of a zoonotic character, and therefore are of great epidemiological importance. In our country, continuous monitoring of Culicolides spp. has been carried out and seasonal dynamics of their appearance in the period 2015-2016 is presented in this article. During October 2015, the presence of Culicolides spp. was confirmed in 10.00% of samples; in November, their presence was not established, whereas in December, 2.35% of samples proved positive for the presence of Culicolides spp. During 2016, from January to March, no Culicolides spp. were found in any of the examined samples. During April, their prevalence was 9.63%, in May - 6.74%, in June - 3.70%, in July - 15.78%, in August - 18.07%, in September - 27.27%, and in October - 45.65%. In Serbia, the dominant Culicoides spp. species are Obsoletus complex and Pulicaris complex established in 57.21% and 33.37% of samples, respectively. Other species are present in lesser extent. In Obsoletus complex, the dominant species was Culicoides obsoletus/scoticus. The percentage of Culicoides obsoletus /scoticus males in samples was 25.52%. Non-pigmented (young) females were present in 66.06% of samples; females who took blood in 7.55% and 0.87% were gravid females. In Pulicaris complex, the dominant species was Culicoides pulicaris. Males of Culicoides pulicaris were found in 19.23% of samples, non-pigmented (young) females in 70.96%, females who took blood in 9.08% while 0.73% were gravid females.
AB  - Rod Culicoides spp. su mali insekti veličine 0,5-2 mm, većinom sivkaste ili  crne  boje  i  na  prvi  pogled  veoma  slični  komarcima. Oni  su  striktne  hematofage. Ubod  je  veoma  bolan,  a  mesta  uboda  su  često  hipersenzibilisana  uz  posledično  nastajanje  alergijskih  dermatitisa. Uz  to  oni  prenose  mnoštvo  oboljenja  često  zoonotskog  karaktera  tako  da  su  od  izuzetnog  epidemiološkog  značaja. U  našoj  zemlji  se  vrši  stalni  monitoring  Culicolides-a  i  ovde  dajemo  prikaz  sezonske  dinamike  njihovog  pojavljivanja  u  periodu  2015-2016.godine. Tokom  2015.  godine  u  oktobru  je  njihovo  prisustvo ustanovljeno u 10.,00% uzoraka, u novembru ih nije bilo, a tokom decembra su bili prisutni u 2,35%. Tokom 2016. godine tokom januara, februara  i  marta  nisu  nađeni  ni  u  jednom  prispelom  uzorku. Tokom  aprila  meseca njihova prevalencija je iznosila 9,63%, u maju je bila 6,74%, u junu 3,70%, u julu 15,78%, u avgustu 18,07%, u septembru 27,27% i u oktobru 45,65%. U  Srbiji  su  dominantne  vrste  Culicoides spp.  iz  Obsoletus  kompleksa  i  ustanovljeni  su  u  57,21%.  Culicoides spp.  iz  Pulicaris  kompleksa  ustanovljeni  su  33,37%  dok  su  ostale  vrste  manje  zastupljene.  Kod  Culicoides  spp.  iz  Obsoletus  kompleksa  dominantna  vrsta  je  bila  Culicoides obsoletus/scoticus.  Mužjaci  su  nađeni  u  25,52%,  nepigmentisane  (mlade)  ženke u 66,06%, ženke koje su uzele krv u 7,55%, a 0,87% su bile gravidne ženke. Kod Culicoides spp. iz Pulicaris kompleksa dominantna vrsta je bila Culicoides pulicaris. Mužjaci su nađeni u 19,23%, nepigmentisane (mlade) ženke u 70,96%, ženke koje su uzele krv u 9,08%, a 0,73% su bile gravidne ženke.
PB  - Scientific Veterinary Institute “Novi Sad”, Novi Sad
T2  - Archives of Veterinary Medicine
T1  - Seasonal dynamics of the presence of culicoides spp. in Serbia in the period 2015-2016
T1  - Sezonska dinamika prisustva culicoides spp u Srbiji u periodu 2015-2016. godine
VL  - 10
IS  - 1
DO  - 10.46784/e-avm.v10i1.76
ER  - 
@article{
author = "Pavlović, Ivan and Veljović, Ljubiša and Milićević, Vesna and Maksimović-Zorić, Jelena and Stanojević, Slobodan and Radanović, Oliver and Đurić, Boban and Plavšić, Budimir and Vasić, Ana",
year = "2019",
abstract = "Genus Culicoides spp. includes small insects 0.5-2 mm in length, usually grey or black and at first glance very similar to mosquitoes. They are strictly hematophagous, feeding by attacking hosts outdoors and indoors (although they are less susceptible to the stationing like Aedes mosquitoes do). The sting is very painful at the injection site and often followed by hypersensibilisation with the consequent formation of allergic dermatitis. In addition, the insects carry and transmit a multitude of diseases, often of a zoonotic character, and therefore are of great epidemiological importance. In our country, continuous monitoring of Culicolides spp. has been carried out and seasonal dynamics of their appearance in the period 2015-2016 is presented in this article. During October 2015, the presence of Culicolides spp. was confirmed in 10.00% of samples; in November, their presence was not established, whereas in December, 2.35% of samples proved positive for the presence of Culicolides spp. During 2016, from January to March, no Culicolides spp. were found in any of the examined samples. During April, their prevalence was 9.63%, in May - 6.74%, in June - 3.70%, in July - 15.78%, in August - 18.07%, in September - 27.27%, and in October - 45.65%. In Serbia, the dominant Culicoides spp. species are Obsoletus complex and Pulicaris complex established in 57.21% and 33.37% of samples, respectively. Other species are present in lesser extent. In Obsoletus complex, the dominant species was Culicoides obsoletus/scoticus. The percentage of Culicoides obsoletus /scoticus males in samples was 25.52%. Non-pigmented (young) females were present in 66.06% of samples; females who took blood in 7.55% and 0.87% were gravid females. In Pulicaris complex, the dominant species was Culicoides pulicaris. Males of Culicoides pulicaris were found in 19.23% of samples, non-pigmented (young) females in 70.96%, females who took blood in 9.08% while 0.73% were gravid females., Rod Culicoides spp. su mali insekti veličine 0,5-2 mm, većinom sivkaste ili  crne  boje  i  na  prvi  pogled  veoma  slični  komarcima. Oni  su  striktne  hematofage. Ubod  je  veoma  bolan,  a  mesta  uboda  su  često  hipersenzibilisana  uz  posledično  nastajanje  alergijskih  dermatitisa. Uz  to  oni  prenose  mnoštvo  oboljenja  često  zoonotskog  karaktera  tako  da  su  od  izuzetnog  epidemiološkog  značaja. U  našoj  zemlji  se  vrši  stalni  monitoring  Culicolides-a  i  ovde  dajemo  prikaz  sezonske  dinamike  njihovog  pojavljivanja  u  periodu  2015-2016.godine. Tokom  2015.  godine  u  oktobru  je  njihovo  prisustvo ustanovljeno u 10.,00% uzoraka, u novembru ih nije bilo, a tokom decembra su bili prisutni u 2,35%. Tokom 2016. godine tokom januara, februara  i  marta  nisu  nađeni  ni  u  jednom  prispelom  uzorku. Tokom  aprila  meseca njihova prevalencija je iznosila 9,63%, u maju je bila 6,74%, u junu 3,70%, u julu 15,78%, u avgustu 18,07%, u septembru 27,27% i u oktobru 45,65%. U  Srbiji  su  dominantne  vrste  Culicoides spp.  iz  Obsoletus  kompleksa  i  ustanovljeni  su  u  57,21%.  Culicoides spp.  iz  Pulicaris  kompleksa  ustanovljeni  su  33,37%  dok  su  ostale  vrste  manje  zastupljene.  Kod  Culicoides  spp.  iz  Obsoletus  kompleksa  dominantna  vrsta  je  bila  Culicoides obsoletus/scoticus.  Mužjaci  su  nađeni  u  25,52%,  nepigmentisane  (mlade)  ženke u 66,06%, ženke koje su uzele krv u 7,55%, a 0,87% su bile gravidne ženke. Kod Culicoides spp. iz Pulicaris kompleksa dominantna vrsta je bila Culicoides pulicaris. Mužjaci su nađeni u 19,23%, nepigmentisane (mlade) ženke u 70,96%, ženke koje su uzele krv u 9,08%, a 0,73% su bile gravidne ženke.",
publisher = "Scientific Veterinary Institute “Novi Sad”, Novi Sad",
journal = "Archives of Veterinary Medicine",
title = "Seasonal dynamics of the presence of culicoides spp. in Serbia in the period 2015-2016, Sezonska dinamika prisustva culicoides spp u Srbiji u periodu 2015-2016. godine",
volume = "10",
number = "1",
doi = "10.46784/e-avm.v10i1.76"
}
Pavlović, I., Veljović, L., Milićević, V., Maksimović-Zorić, J., Stanojević, S., Radanović, O., Đurić, B., Plavšić, B.,& Vasić, A.. (2019). Seasonal dynamics of the presence of culicoides spp. in Serbia in the period 2015-2016. in Archives of Veterinary Medicine
Scientific Veterinary Institute “Novi Sad”, Novi Sad., 10(1).
https://doi.org/10.46784/e-avm.v10i1.76
Pavlović I, Veljović L, Milićević V, Maksimović-Zorić J, Stanojević S, Radanović O, Đurić B, Plavšić B, Vasić A. Seasonal dynamics of the presence of culicoides spp. in Serbia in the period 2015-2016. in Archives of Veterinary Medicine. 2019;10(1).
doi:10.46784/e-avm.v10i1.76 .
Pavlović, Ivan, Veljović, Ljubiša, Milićević, Vesna, Maksimović-Zorić, Jelena, Stanojević, Slobodan, Radanović, Oliver, Đurić, Boban, Plavšić, Budimir, Vasić, Ana, "Seasonal dynamics of the presence of culicoides spp. in Serbia in the period 2015-2016" in Archives of Veterinary Medicine, 10, no. 1 (2019),
https://doi.org/10.46784/e-avm.v10i1.76 . .
1

Nalaz gljivica u uzorcima živine

Zdravković, Nemanja; Radanović, Oliver; Spalević, Ljiljana; Maslić-Strižak, Danka; Savić Radovanović, Radoslava; Kureljušić, Jasna

(Banja Luka : Veterinarska komora Republike Srpske, 2018)

TY  - CONF
AU  - Zdravković, Nemanja
AU  - Radanović, Oliver
AU  - Spalević, Ljiljana
AU  - Maslić-Strižak, Danka
AU  - Savić Radovanović, Radoslava
AU  - Kureljušić, Jasna
PY  - 2018
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2885
AB  - Производња и потрошња конзумних јаја и меса живине је у сталном порасту
како у Републици Србији тако и у свету. Микробиолошко испитивање
приплодних и конзумних јаја спроводи се ради усмеравања ветеринарских и
зоотехничких мера у производњи са циљем заштите здравља животиња и људи.
Контаминација снесених јаја различитим врстама микроорганизама настаје
најчешће из спољне средине. Јаја су због свог хемијског састава добар медијум
за развој различите микрофлоре укључујући патогене микроорганизме.
Контаминација приплодних јаја гљивицама има директан утицај на
контаминацију инкубатора, развој и виталност ембриона, проценат лежења
пилића и развој болести у јатима.
До контаминација јаја долази како у објектима са живином тако и током
транспорта и лагеровања јаја. Извори гљивица у живинарском објекту су
различити: простирка, храна, ваздух, амбалажа и сл. У живинарским објектима
могуће је наћи 104-1012 спора у m3 ваздуха у зависности од начина смештаја,
старости јата густине насељености, врсте, облика (брашно, пелете) и квалитета
хране.
Материјал за рад је представљало 288 узорака прикупљених у периоду од 2016-
2017. године. Гљивице су изоловане класичним микробиолошким засејавањем
на Sabouraud агар уз идентификацију на основу морфолошких и фенотипских
особина.
Резултати су показали да је од 288 збирних узорака позитивних на испитивање
присуства гљивица највише било узорака лешева јенодневих пилића (46,96%) а
затим: јаја (15,79%), подлошки (17,77%), органа (12,96%), брисева (10,12%) и
простирки (0,40%). По врстама је најзаступљенија домаћа кокош са 93%
узорака, а затим следе фазани (7,30%), лабудови (1%) и ћурке (0,7%). Описано
је 159 изолата од којих је за 135 (84,91%) изолата извршена идентификација
само до нивоа рода Aspergillus, а 9 (5,66%) изолата је идентификовано каоA.niger, 6 (3,77%) изолата као A.flavus, 8 (5,03%) изолата као Mucor sp. и 1
(0,63%) изолат као Penicillium sp. Због могућих последица услед присуства
патогених гљивица у инкубаторским објектима, које се огледају у низу
симптома, од смрти ембриона, смањења отпорности до ширења инфекције у
ваљаонику треба интензивно примењивати зоотехничке мере, које утичу на
смањење контаминације.
AB  - The production and consumption of eggs and poultry meat is in the constant
growth both in the Republic of Sebia and in the world. The microbiological load of
breeding and table eggs is carried out in order to direct veterinary and zootechnical
measures in framing with the aim of protecting the health of animals and humans.
Contamination of the eggs originates from various types of microorganisms, and
occurs most often from the environment. Due to eggs chemical content they
represent an ideal medium for the development of different microflora including
pathogenic microorganisms. Contamination of breeding eggs with fungi has a
direct relationship with the pollution of the incubator, the development and vitality
of embryos, the percentage of laying chickens and the development of diseases in
flocks.
Contamination of eggs occurs in flock surrounding,as well, during the transport
and storage of eggs. The sources of fungi are various such as mats, food, air,
packaging, etc. In poultry farms it is possible to find up to 104-1012 spores in m3 of
air depending on the way of accommodation, age of flock, population density,
quality and type of food (powder, pellets).
Мaterial represented samples colected during the period from 2016 – 2017 year.
The fungi were isolated by classical microbiological procedure on the Sabouraud
agar followed by identification based on morphological and phenotypic
characteristics.
Our results showed that 288 group samples were positive for the presence of fungi
and the highest number of samples were one day chicks corpses (46.96%), followed
by eggs (15.79%), transport plates (17.77%), organs (12.96%), swabs (10.12%) and
floor samples (0.40%). By species, the most common were domestic chickens with
93% of the samples, followed by pheasants (7.30%), swans (1%) and turkeys
(0.7%). Of the total number of positive group samples, 159 isolates were described
and amoung them in 135 (84.91%) isolates, identification was performed only up to
the Aspergillus genus., 9 (5.66%) isolates were identified as A. niger, 6 (3.77%)isolates were identified as A. flavus, 8 (5.03%) isolates as Mucor sp. and 1 (0.63%)
isoalte as Penicillium sp. Since the consequences of the presence of pathogenic
fungi in the incubatory objects can be followed by series symptoms, from the death
of embryos, reduction in resistance to spreading infection in the roller, zootchnical
measures should be intensively applied reduceing the contamination.
PB  - Banja Luka : Veterinarska komora Republike Srpske
C3  - 23. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina) sa međunarodnim učešćem, Teslić, 6-9. jun 2018.
T1  - Nalaz gljivica u uzorcima živine
T1  - Occurrence of fungi in poltry samples
SP  - 69
EP  - 72
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2885
ER  - 
@conference{
author = "Zdravković, Nemanja and Radanović, Oliver and Spalević, Ljiljana and Maslić-Strižak, Danka and Savić Radovanović, Radoslava and Kureljušić, Jasna",
year = "2018",
abstract = "Производња и потрошња конзумних јаја и меса живине је у сталном порасту
како у Републици Србији тако и у свету. Микробиолошко испитивање
приплодних и конзумних јаја спроводи се ради усмеравања ветеринарских и
зоотехничких мера у производњи са циљем заштите здравља животиња и људи.
Контаминација снесених јаја различитим врстама микроорганизама настаје
најчешће из спољне средине. Јаја су због свог хемијског састава добар медијум
за развој различите микрофлоре укључујући патогене микроорганизме.
Контаминација приплодних јаја гљивицама има директан утицај на
контаминацију инкубатора, развој и виталност ембриона, проценат лежења
пилића и развој болести у јатима.
До контаминација јаја долази како у објектима са живином тако и током
транспорта и лагеровања јаја. Извори гљивица у живинарском објекту су
различити: простирка, храна, ваздух, амбалажа и сл. У живинарским објектима
могуће је наћи 104-1012 спора у m3 ваздуха у зависности од начина смештаја,
старости јата густине насељености, врсте, облика (брашно, пелете) и квалитета
хране.
Материјал за рад је представљало 288 узорака прикупљених у периоду од 2016-
2017. године. Гљивице су изоловане класичним микробиолошким засејавањем
на Sabouraud агар уз идентификацију на основу морфолошких и фенотипских
особина.
Резултати су показали да је од 288 збирних узорака позитивних на испитивање
присуства гљивица највише било узорака лешева јенодневих пилића (46,96%) а
затим: јаја (15,79%), подлошки (17,77%), органа (12,96%), брисева (10,12%) и
простирки (0,40%). По врстама је најзаступљенија домаћа кокош са 93%
узорака, а затим следе фазани (7,30%), лабудови (1%) и ћурке (0,7%). Описано
је 159 изолата од којих је за 135 (84,91%) изолата извршена идентификација
само до нивоа рода Aspergillus, а 9 (5,66%) изолата је идентификовано каоA.niger, 6 (3,77%) изолата као A.flavus, 8 (5,03%) изолата као Mucor sp. и 1
(0,63%) изолат као Penicillium sp. Због могућих последица услед присуства
патогених гљивица у инкубаторским објектима, које се огледају у низу
симптома, од смрти ембриона, смањења отпорности до ширења инфекције у
ваљаонику треба интензивно примењивати зоотехничке мере, које утичу на
смањење контаминације., The production and consumption of eggs and poultry meat is in the constant
growth both in the Republic of Sebia and in the world. The microbiological load of
breeding and table eggs is carried out in order to direct veterinary and zootechnical
measures in framing with the aim of protecting the health of animals and humans.
Contamination of the eggs originates from various types of microorganisms, and
occurs most often from the environment. Due to eggs chemical content they
represent an ideal medium for the development of different microflora including
pathogenic microorganisms. Contamination of breeding eggs with fungi has a
direct relationship with the pollution of the incubator, the development and vitality
of embryos, the percentage of laying chickens and the development of diseases in
flocks.
Contamination of eggs occurs in flock surrounding,as well, during the transport
and storage of eggs. The sources of fungi are various such as mats, food, air,
packaging, etc. In poultry farms it is possible to find up to 104-1012 spores in m3 of
air depending on the way of accommodation, age of flock, population density,
quality and type of food (powder, pellets).
Мaterial represented samples colected during the period from 2016 – 2017 year.
The fungi were isolated by classical microbiological procedure on the Sabouraud
agar followed by identification based on morphological and phenotypic
characteristics.
Our results showed that 288 group samples were positive for the presence of fungi
and the highest number of samples were one day chicks corpses (46.96%), followed
by eggs (15.79%), transport plates (17.77%), organs (12.96%), swabs (10.12%) and
floor samples (0.40%). By species, the most common were domestic chickens with
93% of the samples, followed by pheasants (7.30%), swans (1%) and turkeys
(0.7%). Of the total number of positive group samples, 159 isolates were described
and amoung them in 135 (84.91%) isolates, identification was performed only up to
the Aspergillus genus., 9 (5.66%) isolates were identified as A. niger, 6 (3.77%)isolates were identified as A. flavus, 8 (5.03%) isolates as Mucor sp. and 1 (0.63%)
isoalte as Penicillium sp. Since the consequences of the presence of pathogenic
fungi in the incubatory objects can be followed by series symptoms, from the death
of embryos, reduction in resistance to spreading infection in the roller, zootchnical
measures should be intensively applied reduceing the contamination.",
publisher = "Banja Luka : Veterinarska komora Republike Srpske",
journal = "23. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina) sa međunarodnim učešćem, Teslić, 6-9. jun 2018.",
title = "Nalaz gljivica u uzorcima živine, Occurrence of fungi in poltry samples",
pages = "69-72",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2885"
}
Zdravković, N., Radanović, O., Spalević, L., Maslić-Strižak, D., Savić Radovanović, R.,& Kureljušić, J.. (2018). Nalaz gljivica u uzorcima živine. in 23. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina) sa međunarodnim učešćem, Teslić, 6-9. jun 2018.
Banja Luka : Veterinarska komora Republike Srpske., 69-72.
https://hdl.handle.net/21.15107/rcub_veterinar_2885
Zdravković N, Radanović O, Spalević L, Maslić-Strižak D, Savić Radovanović R, Kureljušić J. Nalaz gljivica u uzorcima živine. in 23. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina) sa međunarodnim učešćem, Teslić, 6-9. jun 2018.. 2018;:69-72.
https://hdl.handle.net/21.15107/rcub_veterinar_2885 .
Zdravković, Nemanja, Radanović, Oliver, Spalević, Ljiljana, Maslić-Strižak, Danka, Savić Radovanović, Radoslava, Kureljušić, Jasna, "Nalaz gljivica u uzorcima živine" in 23. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina) sa međunarodnim učešćem, Teslić, 6-9. jun 2018. (2018):69-72,
https://hdl.handle.net/21.15107/rcub_veterinar_2885 .

Enteritis associated with Clostridium perfringens type A in 9-month-old calves

Savić, Božidar; Prodanović, Radiša; Ivetić, Vojin; Radanović, Oliver; Bojkovski, Jovan

(Canadian Vet Med Assoc, Ottawa, 2012)

TY  - JOUR
AU  - Savić, Božidar
AU  - Prodanović, Radiša
AU  - Ivetić, Vojin
AU  - Radanović, Oliver
AU  - Bojkovski, Jovan
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/887
AB  - Four 9-month-old Simmental male calves were presented with a history of sudden death. The necropsy and microscopic findings allowed a diagnosis of enteritis and severe intraluminal hemorrhage with blood clots in the jejunum, suggestive of jejunal hemorrhage syndrome.
PB  - Canadian Vet Med Assoc, Ottawa
T2  - Canadian Veterinary Journal-Revue Veterinaire Canadienne
T1  - Enteritis associated with Clostridium perfringens type A in 9-month-old calves
VL  - 53
IS  - 2
SP  - 174
EP  - 176
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_887
ER  - 
@article{
author = "Savić, Božidar and Prodanović, Radiša and Ivetić, Vojin and Radanović, Oliver and Bojkovski, Jovan",
year = "2012",
abstract = "Four 9-month-old Simmental male calves were presented with a history of sudden death. The necropsy and microscopic findings allowed a diagnosis of enteritis and severe intraluminal hemorrhage with blood clots in the jejunum, suggestive of jejunal hemorrhage syndrome.",
publisher = "Canadian Vet Med Assoc, Ottawa",
journal = "Canadian Veterinary Journal-Revue Veterinaire Canadienne",
title = "Enteritis associated with Clostridium perfringens type A in 9-month-old calves",
volume = "53",
number = "2",
pages = "174-176",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_887"
}
Savić, B., Prodanović, R., Ivetić, V., Radanović, O.,& Bojkovski, J.. (2012). Enteritis associated with Clostridium perfringens type A in 9-month-old calves. in Canadian Veterinary Journal-Revue Veterinaire Canadienne
Canadian Vet Med Assoc, Ottawa., 53(2), 174-176.
https://hdl.handle.net/21.15107/rcub_veterinar_887
Savić B, Prodanović R, Ivetić V, Radanović O, Bojkovski J. Enteritis associated with Clostridium perfringens type A in 9-month-old calves. in Canadian Veterinary Journal-Revue Veterinaire Canadienne. 2012;53(2):174-176.
https://hdl.handle.net/21.15107/rcub_veterinar_887 .
Savić, Božidar, Prodanović, Radiša, Ivetić, Vojin, Radanović, Oliver, Bojkovski, Jovan, "Enteritis associated with Clostridium perfringens type A in 9-month-old calves" in Canadian Veterinary Journal-Revue Veterinaire Canadienne, 53, no. 2 (2012):174-176,
https://hdl.handle.net/21.15107/rcub_veterinar_887 .
7
11

Paratuberculosis in breeding stock of red Holstein cows

Prodanović, Radiša; Vujanac, Ivan; Kirovski, Danijela; Ivetić, Vojin; Savić, Božidar; Žutić, Milenko; Kureljušić, Branislav; Radanović, Oliver

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2011)

TY  - JOUR
AU  - Prodanović, Radiša
AU  - Vujanac, Ivan
AU  - Kirovski, Danijela
AU  - Ivetić, Vojin
AU  - Savić, Božidar
AU  - Žutić, Milenko
AU  - Kureljušić, Branislav
AU  - Radanović, Oliver
PY  - 2011
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/818
AB  - This paper describes paratuberculosis in an isolated breeding herd of 25 high-yield dairy cows of the Red Holstein breed. The animals were examined clinically and then given the test for ldelayed type hypersensitivity and their blood serum was examined for the presence of specific antibodies against Mycobacterium avium subsp. paratuberculosis (Map). The clinical examination revealed that two cows exhibited symptoms of the disease that indicated an advanced stage of paratuberculosis. The following parameters were examined in the blood of the cows that showed clinical signs of the disease: leukocytes and erythrocytes count, concentrations of total proteins, albumin, iron, sodium, potassium, and activity of creatine kinase. The analysis of the red blood cell count revealed certain digressions that indicated the existence of hypochromic microcytic anaemia. The number of leukocytes was within the physiological values, but the neutrophil-lymphocyte ratio was disrupted and stood at almost 1:1. The results of the biochemical analyses of the blood serum of diseased cows indicated hypoproteinaemia, hypoalbuminaemia, hypoferremia, hyposodiumaemia, hypokalemia, and increased activities of creatine kinase enzymes. A suspect reaction on the site of application of avian tuberculin was determined in two animals. Animals with clinical signs of the disease reacted negative to the test of delayed type hypersensitivity. The presence of specific antibodies against the cause of paratuberculosis was proven in four animals (16%), including two animals with clinical signs of the disease and one that had a suspect reaction on the site of application of avian tuberculin. Furthermore, one animal that died exhibited macroscopic and microscopic changes regarding the intensity and distribution of lesions, the type of cellular infiltrate, and the number of present acidresistent bacteria, and the changes were characterized as diffuse changes of multibacillary type. The cause of bovine paratuberculosis was isolated from the altered organs.
AB  - U ovom radu opisana je paratuberkuloza u izolovanom zapatu od 25 visokomlečnih krava rase crveni holštajn. Životinje u zapatu su klinič ki pregledane, a zatim podvrgnute testu kasne preosetljivosti i ispitivanju krvnog seruma na prisustvo specifičnih antitela protiv Mycobacterium avium subsp. paratuberculosis (Map). Kliničkim pregledom kod dve životinje uočeni su simptomi bolesti koji su ukazivali na uznapredovali stadijum paratuberkuloze. U krvi krava koje su pokazivale kliničke znake bolesti određivani su parametri crvene i bele krvne slike, koncentracija ukupnih proteina, albumina, gvožđa, natrijuma, kalijuma i aktivnost kreatin kinaze. Analizom parametara crvene krvne slike utvrđena su izvesna odstupanja koja su ukazivala na postojanje hipohromne mikrocitne anemije. Broj leukocita je bio u okviru fizioloških vrednosti, ali je neutrofilno-limfocitni količnik bio narušen i iznosio skoro 1:1. Rezultati biohemijskih analiza krvnog seruma obolelih krava ukazali su na hipoproteinemiju, hipoalbuminemiju, hipoferemiju, hiponatremiju, hipokalemiju i povećanu aktivnost enzima kreatin kinaze. Sumnjiva reakcija na mestu aplikacije avijarnog tuberkulina je ustanovljena kod dve životinje. Životinje sa kliničkim znakovima bolesti su bile negativne na test kasne preosetljivosti. Prisustvo specifičnih antitela protiv uzročnika paratuberkuloze dokazano je kod četiri životinje (16%), uključujući dve životinje sa kliničkim znakovima bolesti i jednu koja je imala sumnjivu reakciju na mestu aplikacija avijarnog tuberkulina. Pored toga, kod jedne uginule životinje opisane su makroskopske i mikroskopske promene u odnosu na intenzitet i distribuciju lezija, tip ćelijskog infiltrata i broja prisutnih acidorezistentnih bakterija, a promene su okarakterisane kao difuzne promene multibacilarnog tipa. Iz promenjenih organa izvršena je izolacija uzročnika bovine paratuberkuloze.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Paratuberculosis in breeding stock of red Holstein cows
T1  - Paratuberkuloza u zapatu krava rase crveni holštajn
VL  - 65
IS  - 3-4
SP  - 179
EP  - 190
DO  - 10.2298/VETGL1104179P
ER  - 
@article{
author = "Prodanović, Radiša and Vujanac, Ivan and Kirovski, Danijela and Ivetić, Vojin and Savić, Božidar and Žutić, Milenko and Kureljušić, Branislav and Radanović, Oliver",
year = "2011",
abstract = "This paper describes paratuberculosis in an isolated breeding herd of 25 high-yield dairy cows of the Red Holstein breed. The animals were examined clinically and then given the test for ldelayed type hypersensitivity and their blood serum was examined for the presence of specific antibodies against Mycobacterium avium subsp. paratuberculosis (Map). The clinical examination revealed that two cows exhibited symptoms of the disease that indicated an advanced stage of paratuberculosis. The following parameters were examined in the blood of the cows that showed clinical signs of the disease: leukocytes and erythrocytes count, concentrations of total proteins, albumin, iron, sodium, potassium, and activity of creatine kinase. The analysis of the red blood cell count revealed certain digressions that indicated the existence of hypochromic microcytic anaemia. The number of leukocytes was within the physiological values, but the neutrophil-lymphocyte ratio was disrupted and stood at almost 1:1. The results of the biochemical analyses of the blood serum of diseased cows indicated hypoproteinaemia, hypoalbuminaemia, hypoferremia, hyposodiumaemia, hypokalemia, and increased activities of creatine kinase enzymes. A suspect reaction on the site of application of avian tuberculin was determined in two animals. Animals with clinical signs of the disease reacted negative to the test of delayed type hypersensitivity. The presence of specific antibodies against the cause of paratuberculosis was proven in four animals (16%), including two animals with clinical signs of the disease and one that had a suspect reaction on the site of application of avian tuberculin. Furthermore, one animal that died exhibited macroscopic and microscopic changes regarding the intensity and distribution of lesions, the type of cellular infiltrate, and the number of present acidresistent bacteria, and the changes were characterized as diffuse changes of multibacillary type. The cause of bovine paratuberculosis was isolated from the altered organs., U ovom radu opisana je paratuberkuloza u izolovanom zapatu od 25 visokomlečnih krava rase crveni holštajn. Životinje u zapatu su klinič ki pregledane, a zatim podvrgnute testu kasne preosetljivosti i ispitivanju krvnog seruma na prisustvo specifičnih antitela protiv Mycobacterium avium subsp. paratuberculosis (Map). Kliničkim pregledom kod dve životinje uočeni su simptomi bolesti koji su ukazivali na uznapredovali stadijum paratuberkuloze. U krvi krava koje su pokazivale kliničke znake bolesti određivani su parametri crvene i bele krvne slike, koncentracija ukupnih proteina, albumina, gvožđa, natrijuma, kalijuma i aktivnost kreatin kinaze. Analizom parametara crvene krvne slike utvrđena su izvesna odstupanja koja su ukazivala na postojanje hipohromne mikrocitne anemije. Broj leukocita je bio u okviru fizioloških vrednosti, ali je neutrofilno-limfocitni količnik bio narušen i iznosio skoro 1:1. Rezultati biohemijskih analiza krvnog seruma obolelih krava ukazali su na hipoproteinemiju, hipoalbuminemiju, hipoferemiju, hiponatremiju, hipokalemiju i povećanu aktivnost enzima kreatin kinaze. Sumnjiva reakcija na mestu aplikacije avijarnog tuberkulina je ustanovljena kod dve životinje. Životinje sa kliničkim znakovima bolesti su bile negativne na test kasne preosetljivosti. Prisustvo specifičnih antitela protiv uzročnika paratuberkuloze dokazano je kod četiri životinje (16%), uključujući dve životinje sa kliničkim znakovima bolesti i jednu koja je imala sumnjivu reakciju na mestu aplikacija avijarnog tuberkulina. Pored toga, kod jedne uginule životinje opisane su makroskopske i mikroskopske promene u odnosu na intenzitet i distribuciju lezija, tip ćelijskog infiltrata i broja prisutnih acidorezistentnih bakterija, a promene su okarakterisane kao difuzne promene multibacilarnog tipa. Iz promenjenih organa izvršena je izolacija uzročnika bovine paratuberkuloze.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Paratuberculosis in breeding stock of red Holstein cows, Paratuberkuloza u zapatu krava rase crveni holštajn",
volume = "65",
number = "3-4",
pages = "179-190",
doi = "10.2298/VETGL1104179P"
}
Prodanović, R., Vujanac, I., Kirovski, D., Ivetić, V., Savić, B., Žutić, M., Kureljušić, B.,& Radanović, O.. (2011). Paratuberculosis in breeding stock of red Holstein cows. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 65(3-4), 179-190.
https://doi.org/10.2298/VETGL1104179P
Prodanović R, Vujanac I, Kirovski D, Ivetić V, Savić B, Žutić M, Kureljušić B, Radanović O. Paratuberculosis in breeding stock of red Holstein cows. in Veterinarski Glasnik. 2011;65(3-4):179-190.
doi:10.2298/VETGL1104179P .
Prodanović, Radiša, Vujanac, Ivan, Kirovski, Danijela, Ivetić, Vojin, Savić, Božidar, Žutić, Milenko, Kureljušić, Branislav, Radanović, Oliver, "Paratuberculosis in breeding stock of red Holstein cows" in Veterinarski Glasnik, 65, no. 3-4 (2011):179-190,
https://doi.org/10.2298/VETGL1104179P . .

Comparative investigation on the efficacy of tulathromycin and florfenicol in the treatment of bronchopneumonia in feedlot calves

Jezdimirović, Milanka; Aleksić, Nevenka; Barać-Bašević, Ana; Žutić, Milenko; Ivetić, Vojin; Radanović, Oliver; Jezdimirović, Nemanja

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2011)

TY  - JOUR
AU  - Jezdimirović, Milanka
AU  - Aleksić, Nevenka
AU  - Barać-Bašević, Ana
AU  - Žutić, Milenko
AU  - Ivetić, Vojin
AU  - Radanović, Oliver
AU  - Jezdimirović, Nemanja
PY  - 2011
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/834
AB  - The clinical efficacy of tulathromycin (TU) and florfenicol (FL) in the treatment of bronchopneumonia (BP) caused by Pasteurella multocida which was isolated from nose swabs of diseased calves has been examined. The symptoms of bronchopneumonia (BP) were quantified by means of the clinical score (CS) with a maximum of 47 points. In the current investigation the average CS in diseased calves was 23.5± 0.15. The clinical efficacy of TU and FL was assessed every day in the first week after the administration of the drugs and was based on the decrease in CS and on microbiological findings on days 7, 28 and 35 after the completion of therapy. Tulathromycin was administered s.c., in the prescribed therapeutic dose (2.5 mg/kg BW), and florfenicol s.c., twice at a 48 h interval, in its respective therapeutic dose (40 mg/kg BW). In spite of the repeated administration of FL, TU was significantly more rapid to decrease the major clinical symptoms in the first four days following the application, in comparison with FL (P lt 0.05). On the fourth day after the administration, the clinical efficacy of TU in the therapy of BP in calves was 43.4±1.5 %, and of florfenicol 27.2±1.6 %. However, five days after the application of TU and two days after the repeated application of FL the assessed clinical efficacy of the two antibiotics was roughly the same. The average efficacy of TU was 57.1±0.0%, and of florfenicol 58.5±0.0%, both the individual and mean CS in the treated calves was 10 points, due to hyperthermia, which remained the only symptom. Six days after the administration of TU and three days after the repeated application of FL both antibiotics had equal maximum efficacy (100%) in the treatment of BP. The clinical efficacy remained unchanged on day seven. The recovery was confirmed by the absence of P. multocida in nose swabs sampled on the seventh day after the initial treatment. However, in 4 calves (21.05 %) of the 19 treated Streptococcus alpha haemolyticus was isolated. Four weeks after the completion of the treatment with TU and FL the recurrence of BP caused by P. multocida was noted in 30% of calves treated with TU and 22.22% with FL. Seven days after a single administration of TU and FL, all clinical symptoms of recurrent BP and the microbiological findings were negative. Given the obtained results of the investigation on the efficacy of TU and FL in calves, TU can be recommended as the drug of first choice in the treatment of BP caused by P. multocida. Its insufficient clinical efficacy in the first three days following the application may be enhanced by simultaneous administration of NSAID and bronchodilators.
AB  - Ispitivana je klinička efikasnost tulatromicina (TU) i florfenikola (FL) u lečenju bronhopneumonije (BP) prouzrokovane vrstom Pasteurella multocida, izolovanom iz briseva nosa junadi. Simptomi BP su kvantifikovani da bi se dobio klinički skor (KS) koji definiše težinu kliničke slike kod životinja. Prema korišćenoj skali maksimalna vrednost KS parametara BP iznosi 47 bodova. U našem ogledu, vrednost prosečnog KS kod obolele junadi iznosila je 23,5±0,15. Klinička efikasnost TU i FL procenjivana je svakodnevno, tokom sedam dana, na osnovu povlačenja kliničkih simptoma (smanjivanje vrednosti KS) i prisustva prouzrokovača BP u brisevima nosa 7, 28. i 35. dana od ukidanja terapije. Tulatromicin je aplikovan s.c., jednokratno u terapijskoj dozi od 2,5 mg/kg, a florfenikol s.c., dvokratno u razmaku od 48 h u terapijskoj dozi od 40 mg/kg tm. U ovom ispitivanju TU je u prva četri dana od aplikacije značajno brže od FL (P lt 0,05) dovodio do povlačenja bitnih kliničkih simptoma, iako je aplikacija FL u tom periodu ponovljena. Klinička efikasnost TU u lečenju BP junadi četvrtog dana od primene iznosila je 43,4±1,5 %, a florfenikola 27,2±1,6 %. Međutim, petog dana od aplikacije TU i FL i drugog dana od druge aplikacije FL ustanovljena je približno ista klinička efikasnost ovih antimikrobnih lekova u lečenju BP. Prosečna efikasnost TU bila je 57,1±0,0%, a FL 58,5± 0,0%. Vrednost individualnog i prosečnog KS kod junadi lečene TU i FL iznosila je 10 bodova. Od kliničkih simptoma jedino se hipertermija nije povukla. Šestog dana od aplikacije TU i FL i trećeg dana od druge aplikacije FL oba antibiotika imala su podjednaku, maksimalnu (100%) kliničku efikasnost u lečenju BP. Ista klinička efikasnost zabeležena je i sedmog dana ogleda. Izlečenje je potvrđeno odsustvom P. multocida u brisevima uzetim sedmog dana od početka lečenja. Međutim, kod 4 juneta (21,05 %) od ukupno 19 izolovan je Streptococcus alpha haemolyticus. Četiri nedelje od obustavljanja primene TU i FL uočen je recidiv BP prouzrokovane P. multocida kod 30% junadi lečene TU i 22,22% lečene FL. Posle jednokratne primene TU i FL, sedmog dana su se povukli svi klinički simptomi recidivirajuće BP, a mikrobiološki nalaz bio je negativan. Sumirajući rezultate dobijene uporednim ispitivanjem efikasnosti TU i FL u lečenju BP junadi prouzrokovane P. multocida predlažemo da se TU koristi kao lek prvog izbora u lečenju ove respiratorne infekcije. Njegova efikasnost, nedovoljna u prva tri dana od aplikacije, može da se poveća istovremenom primenom lekova iz grupe NSAIL i bronhodilatatora.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Comparative investigation on the efficacy of tulathromycin and florfenicol in the treatment of bronchopneumonia in feedlot calves
T1  - Uporedno ispitivanje efikasnosti tulatromicina i florfenikola u lečenju bronhopneumonije junadi
VL  - 65
IS  - 3-4
SP  - 153
EP  - 178
DO  - 10.2298/VETGL1104153J
ER  - 
@article{
author = "Jezdimirović, Milanka and Aleksić, Nevenka and Barać-Bašević, Ana and Žutić, Milenko and Ivetić, Vojin and Radanović, Oliver and Jezdimirović, Nemanja",
year = "2011",
abstract = "The clinical efficacy of tulathromycin (TU) and florfenicol (FL) in the treatment of bronchopneumonia (BP) caused by Pasteurella multocida which was isolated from nose swabs of diseased calves has been examined. The symptoms of bronchopneumonia (BP) were quantified by means of the clinical score (CS) with a maximum of 47 points. In the current investigation the average CS in diseased calves was 23.5± 0.15. The clinical efficacy of TU and FL was assessed every day in the first week after the administration of the drugs and was based on the decrease in CS and on microbiological findings on days 7, 28 and 35 after the completion of therapy. Tulathromycin was administered s.c., in the prescribed therapeutic dose (2.5 mg/kg BW), and florfenicol s.c., twice at a 48 h interval, in its respective therapeutic dose (40 mg/kg BW). In spite of the repeated administration of FL, TU was significantly more rapid to decrease the major clinical symptoms in the first four days following the application, in comparison with FL (P lt 0.05). On the fourth day after the administration, the clinical efficacy of TU in the therapy of BP in calves was 43.4±1.5 %, and of florfenicol 27.2±1.6 %. However, five days after the application of TU and two days after the repeated application of FL the assessed clinical efficacy of the two antibiotics was roughly the same. The average efficacy of TU was 57.1±0.0%, and of florfenicol 58.5±0.0%, both the individual and mean CS in the treated calves was 10 points, due to hyperthermia, which remained the only symptom. Six days after the administration of TU and three days after the repeated application of FL both antibiotics had equal maximum efficacy (100%) in the treatment of BP. The clinical efficacy remained unchanged on day seven. The recovery was confirmed by the absence of P. multocida in nose swabs sampled on the seventh day after the initial treatment. However, in 4 calves (21.05 %) of the 19 treated Streptococcus alpha haemolyticus was isolated. Four weeks after the completion of the treatment with TU and FL the recurrence of BP caused by P. multocida was noted in 30% of calves treated with TU and 22.22% with FL. Seven days after a single administration of TU and FL, all clinical symptoms of recurrent BP and the microbiological findings were negative. Given the obtained results of the investigation on the efficacy of TU and FL in calves, TU can be recommended as the drug of first choice in the treatment of BP caused by P. multocida. Its insufficient clinical efficacy in the first three days following the application may be enhanced by simultaneous administration of NSAID and bronchodilators., Ispitivana je klinička efikasnost tulatromicina (TU) i florfenikola (FL) u lečenju bronhopneumonije (BP) prouzrokovane vrstom Pasteurella multocida, izolovanom iz briseva nosa junadi. Simptomi BP su kvantifikovani da bi se dobio klinički skor (KS) koji definiše težinu kliničke slike kod životinja. Prema korišćenoj skali maksimalna vrednost KS parametara BP iznosi 47 bodova. U našem ogledu, vrednost prosečnog KS kod obolele junadi iznosila je 23,5±0,15. Klinička efikasnost TU i FL procenjivana je svakodnevno, tokom sedam dana, na osnovu povlačenja kliničkih simptoma (smanjivanje vrednosti KS) i prisustva prouzrokovača BP u brisevima nosa 7, 28. i 35. dana od ukidanja terapije. Tulatromicin je aplikovan s.c., jednokratno u terapijskoj dozi od 2,5 mg/kg, a florfenikol s.c., dvokratno u razmaku od 48 h u terapijskoj dozi od 40 mg/kg tm. U ovom ispitivanju TU je u prva četri dana od aplikacije značajno brže od FL (P lt 0,05) dovodio do povlačenja bitnih kliničkih simptoma, iako je aplikacija FL u tom periodu ponovljena. Klinička efikasnost TU u lečenju BP junadi četvrtog dana od primene iznosila je 43,4±1,5 %, a florfenikola 27,2±1,6 %. Međutim, petog dana od aplikacije TU i FL i drugog dana od druge aplikacije FL ustanovljena je približno ista klinička efikasnost ovih antimikrobnih lekova u lečenju BP. Prosečna efikasnost TU bila je 57,1±0,0%, a FL 58,5± 0,0%. Vrednost individualnog i prosečnog KS kod junadi lečene TU i FL iznosila je 10 bodova. Od kliničkih simptoma jedino se hipertermija nije povukla. Šestog dana od aplikacije TU i FL i trećeg dana od druge aplikacije FL oba antibiotika imala su podjednaku, maksimalnu (100%) kliničku efikasnost u lečenju BP. Ista klinička efikasnost zabeležena je i sedmog dana ogleda. Izlečenje je potvrđeno odsustvom P. multocida u brisevima uzetim sedmog dana od početka lečenja. Međutim, kod 4 juneta (21,05 %) od ukupno 19 izolovan je Streptococcus alpha haemolyticus. Četiri nedelje od obustavljanja primene TU i FL uočen je recidiv BP prouzrokovane P. multocida kod 30% junadi lečene TU i 22,22% lečene FL. Posle jednokratne primene TU i FL, sedmog dana su se povukli svi klinički simptomi recidivirajuće BP, a mikrobiološki nalaz bio je negativan. Sumirajući rezultate dobijene uporednim ispitivanjem efikasnosti TU i FL u lečenju BP junadi prouzrokovane P. multocida predlažemo da se TU koristi kao lek prvog izbora u lečenju ove respiratorne infekcije. Njegova efikasnost, nedovoljna u prva tri dana od aplikacije, može da se poveća istovremenom primenom lekova iz grupe NSAIL i bronhodilatatora.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Comparative investigation on the efficacy of tulathromycin and florfenicol in the treatment of bronchopneumonia in feedlot calves, Uporedno ispitivanje efikasnosti tulatromicina i florfenikola u lečenju bronhopneumonije junadi",
volume = "65",
number = "3-4",
pages = "153-178",
doi = "10.2298/VETGL1104153J"
}
Jezdimirović, M., Aleksić, N., Barać-Bašević, A., Žutić, M., Ivetić, V., Radanović, O.,& Jezdimirović, N.. (2011). Comparative investigation on the efficacy of tulathromycin and florfenicol in the treatment of bronchopneumonia in feedlot calves. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 65(3-4), 153-178.
https://doi.org/10.2298/VETGL1104153J
Jezdimirović M, Aleksić N, Barać-Bašević A, Žutić M, Ivetić V, Radanović O, Jezdimirović N. Comparative investigation on the efficacy of tulathromycin and florfenicol in the treatment of bronchopneumonia in feedlot calves. in Veterinarski Glasnik. 2011;65(3-4):153-178.
doi:10.2298/VETGL1104153J .
Jezdimirović, Milanka, Aleksić, Nevenka, Barać-Bašević, Ana, Žutić, Milenko, Ivetić, Vojin, Radanović, Oliver, Jezdimirović, Nemanja, "Comparative investigation on the efficacy of tulathromycin and florfenicol in the treatment of bronchopneumonia in feedlot calves" in Veterinarski Glasnik, 65, no. 3-4 (2011):153-178,
https://doi.org/10.2298/VETGL1104153J . .