TY  - JOUR
AU  - Petrujkić, Branko
AU  - Beier, Ross C.
AU  - He, Haiqi
AU  - Genovese, Kenneth J.
AU  - Swaggerty, Christina L.
AU  - Hume, Michael E.
AU  - Crippen, Tawni L.
AU  - Harvey, Roger B.
AU  - Anderson, Robin C.
AU  - Nisbet, David J.
PY  - 2018
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1627
AB  - BACKGROUNDNigella sativa L. (NS) is a plant containing bioactive constituents such as thymoquinone. Extracts of NS improve performance and reduce enteropathogen colonization in poultry and small ruminants, but studies with swine are lacking. In two different studies oral administration of NS extracts at doses equivalent to 0, 1.5 and 4.5g kg(-1) diet was assessed on piglet performance and intestinal carriage of wildtype Escherichia coli and Campylobacter, and Salmonella Typhimurium. RESULTSWildtype E. coli populations in the jejunal and rectal content collected 9days after treatment began were decreased (P0.05). Populations recovered from pigs treated with extract at 1.5 and 4.5g kg(-1) diet were 0.72-1.31 log(10) units lower than the controls (ranging from 6.05 to 6.61 log(10) CFU g(-1)). Wildtype Campylobacter and Salmonella Typhimurium were unaffected by NS treatment. Feed efficiency over the 9days improved linearly (P<0.05) from 3.88 with 0 NS-treated pigs to 1.47 and 1.41 with pigs treated with NS at 1.5 and 4.5g kg(-1) diet, respectively, possibly due to high glutamine/glutamic acid content of the NS extract. CONCLUSIONNS supplementation of weanling pigs improved feed efficiency and helped control intestinal E. coli during this vulnerable production phase.
PB  - Wiley, Hoboken
T2  - Journal of The Science of Food and Agriculture
T1  - Nigella sativa L. as an alternative antibiotic feed supplement and effect on growth performance in weanling pigs
VL  - 98
IS  - 8
SP  - 3175
EP  - 3181
DO  - 10.1002/jsfa.8823
ER  - 

@article{
author = "Petrujkić, Branko and Beier, Ross C. and He, Haiqi and Genovese, Kenneth J. and Swaggerty, Christina L. and Hume, Michael E. and Crippen, Tawni L. and Harvey, Roger B. and Anderson, Robin C. and Nisbet, David J.",
year = "2018",
abstract = "BACKGROUNDNigella sativa L. (NS) is a plant containing bioactive constituents such as thymoquinone. Extracts of NS improve performance and reduce enteropathogen colonization in poultry and small ruminants, but studies with swine are lacking. In two different studies oral administration of NS extracts at doses equivalent to 0, 1.5 and 4.5g kg(-1) diet was assessed on piglet performance and intestinal carriage of wildtype Escherichia coli and Campylobacter, and Salmonella Typhimurium. RESULTSWildtype E. coli populations in the jejunal and rectal content collected 9days after treatment began were decreased (P0.05). Populations recovered from pigs treated with extract at 1.5 and 4.5g kg(-1) diet were 0.72-1.31 log(10) units lower than the controls (ranging from 6.05 to 6.61 log(10) CFU g(-1)). Wildtype Campylobacter and Salmonella Typhimurium were unaffected by NS treatment. Feed efficiency over the 9days improved linearly (P<0.05) from 3.88 with 0 NS-treated pigs to 1.47 and 1.41 with pigs treated with NS at 1.5 and 4.5g kg(-1) diet, respectively, possibly due to high glutamine/glutamic acid content of the NS extract. CONCLUSIONNS supplementation of weanling pigs improved feed efficiency and helped control intestinal E. coli during this vulnerable production phase.",
publisher = "Wiley, Hoboken",
journal = "Journal of The Science of Food and Agriculture",
title = "Nigella sativa L. as an alternative antibiotic feed supplement and effect on growth performance in weanling pigs",
volume = "98",
number = "8",
pages = "3175-3181",
doi = "10.1002/jsfa.8823"
}

Petrujkić, B., Beier, R. C., He, H., Genovese, K. J., Swaggerty, C. L., Hume, M. E., Crippen, T. L., Harvey, R. B., Anderson, R. C.,& Nisbet, D. J.. (2018). Nigella sativa L. as an alternative antibiotic feed supplement and effect on growth performance in weanling pigs. in Journal of The Science of Food and Agriculture
Wiley, Hoboken., 98(8), 3175-3181.
https://doi.org/10.1002/jsfa.8823

Petrujkić B, Beier RC, He H, Genovese KJ, Swaggerty CL, Hume ME, Crippen TL, Harvey RB, Anderson RC, Nisbet DJ. Nigella sativa L. as an alternative antibiotic feed supplement and effect on growth performance in weanling pigs. in Journal of The Science of Food and Agriculture. 2018;98(8):3175-3181.
doi:10.1002/jsfa.8823 .

Petrujkić, Branko, Beier, Ross C., He, Haiqi, Genovese, Kenneth J., Swaggerty, Christina L., Hume, Michael E., Crippen, Tawni L., Harvey, Roger B., Anderson, Robin C., Nisbet, David J., "Nigella sativa L. as an alternative antibiotic feed supplement and effect on growth performance in weanling pigs" in Journal of The Science of Food and Agriculture, 98, no. 8 (2018):3175-3181,
https://doi.org/10.1002/jsfa.8823 . .