TY  - JOUR
AU  - Cadar, Daniel
AU  - Lorincz, Marta
AU  - Kiss, Timea
AU  - Novosel, Dinko
AU  - Podgorska, Katarzyna
AU  - Becskei, Zsolt
AU  - Tuboly, Tamas
AU  - Csagola, Attila
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1001
AB  - To elucidate the spatiotemporal phylodynamics, dispersion and evolutionary processes underlying the emergence of novel porcine parvovirus 2 (PPV2), PPV3 and PPV4 species, we analysed all available complete capsid genes, together with ours, obtained in Europe. Bayesian phylogeography indicates that Romania (PPV2 and PPV4) and Croatia (PPV3) are the most likely ancestral areas from which PPVs have subsequently spread to other European countries and regions. The timescale of our reconstruction supported a relatively recent history of the currently circulating novel PPV species (1920s to 1980s) in the domestic or sylvatic host. While PPV2 strains exhibited a large genetic exchange characterized by significant recombination and gene flow between distinct regions and hosts, PPV3 and PPV4 showed a diversification reflected by the accumulation of geographically structured polymorphisms. The RNA-like evolutionary rates detected inter- and intrahost recombination and the positive selection sites provided evidence that the PPV2-4 capsid gene plays a prominent role in host adaptation.
PB  - Soc General Microbiology, Reading
T2  - Journal of General Virology
T1  - Emerging novel porcine parvoviruses in Europe: origin, evolution, phylodynamics and phylogeography
VL  - 94
SP  - 2330
EP  - 2337
DO  - 10.1099/vir.0.055129-0
ER  - 

@article{
author = "Cadar, Daniel and Lorincz, Marta and Kiss, Timea and Novosel, Dinko and Podgorska, Katarzyna and Becskei, Zsolt and Tuboly, Tamas and Csagola, Attila",
year = "2013",
abstract = "To elucidate the spatiotemporal phylodynamics, dispersion and evolutionary processes underlying the emergence of novel porcine parvovirus 2 (PPV2), PPV3 and PPV4 species, we analysed all available complete capsid genes, together with ours, obtained in Europe. Bayesian phylogeography indicates that Romania (PPV2 and PPV4) and Croatia (PPV3) are the most likely ancestral areas from which PPVs have subsequently spread to other European countries and regions. The timescale of our reconstruction supported a relatively recent history of the currently circulating novel PPV species (1920s to 1980s) in the domestic or sylvatic host. While PPV2 strains exhibited a large genetic exchange characterized by significant recombination and gene flow between distinct regions and hosts, PPV3 and PPV4 showed a diversification reflected by the accumulation of geographically structured polymorphisms. The RNA-like evolutionary rates detected inter- and intrahost recombination and the positive selection sites provided evidence that the PPV2-4 capsid gene plays a prominent role in host adaptation.",
publisher = "Soc General Microbiology, Reading",
journal = "Journal of General Virology",
title = "Emerging novel porcine parvoviruses in Europe: origin, evolution, phylodynamics and phylogeography",
volume = "94",
pages = "2330-2337",
doi = "10.1099/vir.0.055129-0"
}

Cadar, D., Lorincz, M., Kiss, T., Novosel, D., Podgorska, K., Becskei, Z., Tuboly, T.,& Csagola, A.. (2013). Emerging novel porcine parvoviruses in Europe: origin, evolution, phylodynamics and phylogeography. in Journal of General Virology
Soc General Microbiology, Reading., 94, 2330-2337.
https://doi.org/10.1099/vir.0.055129-0

Cadar D, Lorincz M, Kiss T, Novosel D, Podgorska K, Becskei Z, Tuboly T, Csagola A. Emerging novel porcine parvoviruses in Europe: origin, evolution, phylodynamics and phylogeography. in Journal of General Virology. 2013;94:2330-2337.
doi:10.1099/vir.0.055129-0 .

Cadar, Daniel, Lorincz, Marta, Kiss, Timea, Novosel, Dinko, Podgorska, Katarzyna, Becskei, Zsolt, Tuboly, Tamas, Csagola, Attila, "Emerging novel porcine parvoviruses in Europe: origin, evolution, phylodynamics and phylogeography" in Journal of General Virology, 94 (2013):2330-2337,
https://doi.org/10.1099/vir.0.055129-0 . .

TY  - JOUR
AU  - Cadar, Daniel
AU  - Dan, Adam
AU  - Tombacz, Kata
AU  - Lorincz, Marta
AU  - Kiss, Timea
AU  - Becskei, Zsolt
AU  - Spinu, Marina
AU  - Tuboly, Tamas
AU  - Csagola, Attila
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/857
AB  - Porcine parvovirus (PPV) is widespread among swine and is responsible for reproductive failure of susceptible sows, characterized by embryonic and fetal death. Studies showed that PPV in domestic pig is genetically diverse and some strains differ from the ones used for vaccination. Organ samples from wild boars and domestic pigs were collected in Transylvania (Romania) and tested for the presence of PPV by polymerase chain reaction. Positive samples were grouped and 14 from the wild boar and 1 from the domestic pig PPVs were selected for VP1/VP2 sequence analysis and comparison with available GenBank data. The molecular clock analysis revealed that PPV has a relatively recent evolutionary history, originated approximately 120 years ago and the main divergence occurred in the last 20-60 years. Phylogenetic and residue substitution analysis showed that the viruses could be divided into 6 distinct clusters and that wild boar PPVs were partially different and independent from domestic pig PPVs. PPVs of wild boars proved to be more diverse than viruses of domestic pigs. The presence of the highly virulent 27a-like PPV strains in wild boars was also detected.
PB  - Elsevier, Amsterdam
T2  - Infection Genetics and Evolution
T1  - Phylogeny and evolutionary genetics of porcine parvovirus in wild boars
VL  - 12
IS  - 6
SP  - 1163
EP  - 1171
DO  - 10.1016/j.meegid.2012.04.020
ER  - 

@article{
author = "Cadar, Daniel and Dan, Adam and Tombacz, Kata and Lorincz, Marta and Kiss, Timea and Becskei, Zsolt and Spinu, Marina and Tuboly, Tamas and Csagola, Attila",
year = "2012",
abstract = "Porcine parvovirus (PPV) is widespread among swine and is responsible for reproductive failure of susceptible sows, characterized by embryonic and fetal death. Studies showed that PPV in domestic pig is genetically diverse and some strains differ from the ones used for vaccination. Organ samples from wild boars and domestic pigs were collected in Transylvania (Romania) and tested for the presence of PPV by polymerase chain reaction. Positive samples were grouped and 14 from the wild boar and 1 from the domestic pig PPVs were selected for VP1/VP2 sequence analysis and comparison with available GenBank data. The molecular clock analysis revealed that PPV has a relatively recent evolutionary history, originated approximately 120 years ago and the main divergence occurred in the last 20-60 years. Phylogenetic and residue substitution analysis showed that the viruses could be divided into 6 distinct clusters and that wild boar PPVs were partially different and independent from domestic pig PPVs. PPVs of wild boars proved to be more diverse than viruses of domestic pigs. The presence of the highly virulent 27a-like PPV strains in wild boars was also detected.",
publisher = "Elsevier, Amsterdam",
journal = "Infection Genetics and Evolution",
title = "Phylogeny and evolutionary genetics of porcine parvovirus in wild boars",
volume = "12",
number = "6",
pages = "1163-1171",
doi = "10.1016/j.meegid.2012.04.020"
}

Cadar, D., Dan, A., Tombacz, K., Lorincz, M., Kiss, T., Becskei, Z., Spinu, M., Tuboly, T.,& Csagola, A.. (2012). Phylogeny and evolutionary genetics of porcine parvovirus in wild boars. in Infection Genetics and Evolution
Elsevier, Amsterdam., 12(6), 1163-1171.
https://doi.org/10.1016/j.meegid.2012.04.020

Cadar D, Dan A, Tombacz K, Lorincz M, Kiss T, Becskei Z, Spinu M, Tuboly T, Csagola A. Phylogeny and evolutionary genetics of porcine parvovirus in wild boars. in Infection Genetics and Evolution. 2012;12(6):1163-1171.
doi:10.1016/j.meegid.2012.04.020 .

Cadar, Daniel, Dan, Adam, Tombacz, Kata, Lorincz, Marta, Kiss, Timea, Becskei, Zsolt, Spinu, Marina, Tuboly, Tamas, Csagola, Attila, "Phylogeny and evolutionary genetics of porcine parvovirus in wild boars" in Infection Genetics and Evolution, 12, no. 6 (2012):1163-1171,
https://doi.org/10.1016/j.meegid.2012.04.020 . .