Relationship between serum iron and insulin-like growth factor-I concentrations in 10-day-old calves
2014
Аутори
Prodanović, RadišaKirovski, Danijela
Vujanac, Ivan
Dodovski, Petar
Jovanović, Ljubomir
Šamanc, Horea
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Newborn calves are often deficient in iron and progressive reduction in blood iron concentration occurs over the first weeks of life. Some reports indicate the importance of interactions among iron and components of the insulin-like growth factor system. The aim of the study was to determine if there is a relationship between serum iron and insulin-like growth factor-I concentrations in neonatal calves. Blood samples were collected from 16 female Holstein-Friesian calves on day 10 of age. Erythrogram determination and measurements of serum iron, total protein, albumin, total iron binding capacity and serum insulin-like growth factor-I concentrations were performed. Haematological values were measured using an automatic analyzer, biochemical properties were determined spectrophotometrically, insulin-like growth factor-I concentration was measured by radioimmunoassay. Calves were divided into 2 groups according to iron concentrations; the first group of iron-deficient calves (n = 8, Fe <... 10 mu mol/l) and the second group of calves with optimal iron concentration (n = 8, Fe > 18 mu mol/l). Blood indicators in all calves from the first group followed a pattern typically observed in anaemic calves. Insulin-like growth factor-I concentrations were significantly (P < 0.01) lower in the first group compared to the second group. However, insulin-like growth factor-I very strongly correlated with iron in calves from the second group compared to iron-deficient calves (r = 0.624; P < 0.01 and r = 0.478; P > 0.05, respectively). Based on our results, iron seems to have an important relationship to secretion of insulin-like growth factor-I in 10-day-old calves. This is the first report about such relationship in this age group of animals.
Кључне речи:
Calf / haematology / IGF-I / iron deficiencyИзвор:
Acta Veterinaria - Brno, 2014, 83, 2, 133-137Издавач:
- Veterinarni A Farmaceuticka Univerzita Brno, Brno
Финансирање / пројекти:
- Молекуларно-генетичка и екофизиолошка истраживања у заштити аутохтоних анималних генетичких ресурса, очувању добробити, здравља и репродукције гајених животиња и производњи безбедне хране (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46002)
DOI: 10.2754/avb201483020133
ISSN: 0001-7213
WoS: 000339086600011
Scopus: 2-s2.0-84903518689
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Prodanović, Radiša AU - Kirovski, Danijela AU - Vujanac, Ivan AU - Dodovski, Petar AU - Jovanović, Ljubomir AU - Šamanc, Horea PY - 2014 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1112 AB - Newborn calves are often deficient in iron and progressive reduction in blood iron concentration occurs over the first weeks of life. Some reports indicate the importance of interactions among iron and components of the insulin-like growth factor system. The aim of the study was to determine if there is a relationship between serum iron and insulin-like growth factor-I concentrations in neonatal calves. Blood samples were collected from 16 female Holstein-Friesian calves on day 10 of age. Erythrogram determination and measurements of serum iron, total protein, albumin, total iron binding capacity and serum insulin-like growth factor-I concentrations were performed. Haematological values were measured using an automatic analyzer, biochemical properties were determined spectrophotometrically, insulin-like growth factor-I concentration was measured by radioimmunoassay. Calves were divided into 2 groups according to iron concentrations; the first group of iron-deficient calves (n = 8, Fe < 10 mu mol/l) and the second group of calves with optimal iron concentration (n = 8, Fe > 18 mu mol/l). Blood indicators in all calves from the first group followed a pattern typically observed in anaemic calves. Insulin-like growth factor-I concentrations were significantly (P < 0.01) lower in the first group compared to the second group. However, insulin-like growth factor-I very strongly correlated with iron in calves from the second group compared to iron-deficient calves (r = 0.624; P < 0.01 and r = 0.478; P > 0.05, respectively). Based on our results, iron seems to have an important relationship to secretion of insulin-like growth factor-I in 10-day-old calves. This is the first report about such relationship in this age group of animals. PB - Veterinarni A Farmaceuticka Univerzita Brno, Brno T2 - Acta Veterinaria - Brno T1 - Relationship between serum iron and insulin-like growth factor-I concentrations in 10-day-old calves VL - 83 IS - 2 SP - 133 EP - 137 DO - 10.2754/avb201483020133 ER -
@article{ author = "Prodanović, Radiša and Kirovski, Danijela and Vujanac, Ivan and Dodovski, Petar and Jovanović, Ljubomir and Šamanc, Horea", year = "2014", abstract = "Newborn calves are often deficient in iron and progressive reduction in blood iron concentration occurs over the first weeks of life. Some reports indicate the importance of interactions among iron and components of the insulin-like growth factor system. The aim of the study was to determine if there is a relationship between serum iron and insulin-like growth factor-I concentrations in neonatal calves. Blood samples were collected from 16 female Holstein-Friesian calves on day 10 of age. Erythrogram determination and measurements of serum iron, total protein, albumin, total iron binding capacity and serum insulin-like growth factor-I concentrations were performed. Haematological values were measured using an automatic analyzer, biochemical properties were determined spectrophotometrically, insulin-like growth factor-I concentration was measured by radioimmunoassay. Calves were divided into 2 groups according to iron concentrations; the first group of iron-deficient calves (n = 8, Fe < 10 mu mol/l) and the second group of calves with optimal iron concentration (n = 8, Fe > 18 mu mol/l). Blood indicators in all calves from the first group followed a pattern typically observed in anaemic calves. Insulin-like growth factor-I concentrations were significantly (P < 0.01) lower in the first group compared to the second group. However, insulin-like growth factor-I very strongly correlated with iron in calves from the second group compared to iron-deficient calves (r = 0.624; P < 0.01 and r = 0.478; P > 0.05, respectively). Based on our results, iron seems to have an important relationship to secretion of insulin-like growth factor-I in 10-day-old calves. This is the first report about such relationship in this age group of animals.", publisher = "Veterinarni A Farmaceuticka Univerzita Brno, Brno", journal = "Acta Veterinaria - Brno", title = "Relationship between serum iron and insulin-like growth factor-I concentrations in 10-day-old calves", volume = "83", number = "2", pages = "133-137", doi = "10.2754/avb201483020133" }
Prodanović, R., Kirovski, D., Vujanac, I., Dodovski, P., Jovanović, L.,& Šamanc, H.. (2014). Relationship between serum iron and insulin-like growth factor-I concentrations in 10-day-old calves. in Acta Veterinaria - Brno Veterinarni A Farmaceuticka Univerzita Brno, Brno., 83(2), 133-137. https://doi.org/10.2754/avb201483020133
Prodanović R, Kirovski D, Vujanac I, Dodovski P, Jovanović L, Šamanc H. Relationship between serum iron and insulin-like growth factor-I concentrations in 10-day-old calves. in Acta Veterinaria - Brno. 2014;83(2):133-137. doi:10.2754/avb201483020133 .
Prodanović, Radiša, Kirovski, Danijela, Vujanac, Ivan, Dodovski, Petar, Jovanović, Ljubomir, Šamanc, Horea, "Relationship between serum iron and insulin-like growth factor-I concentrations in 10-day-old calves" in Acta Veterinaria - Brno, 83, no. 2 (2014):133-137, https://doi.org/10.2754/avb201483020133 . .