Influence of estradiol on neurons of nucleus basomedialis in the amygdaloid complex of female rats
Апстракт
The amygdaloid complex (AC) of rat brain is sensitive to sex steroids, especially during neonatal development. The aim of this investigation was to determine possible changes in neuron morphology of the basomedial nucleus (BMN) of the AC in female rats treated with estradiol. Two straining techniques were used: (1) standard histological staining with hematoxylin-eosin and (2) the Golgi method. Three types of neurons: pyramidal, fusiform and stellate were subjected to stereologic analaysis. Estradiol significantly increased the volume of neuronal soma of all three neuronal types at 16 and 90 days of age, whereas at day 38 changes were observed only in fusiform and stellate neurons. In addition, the volume of cell nuclei was increased but the number of neurons per unit area decreased at all experimental intervals examined. Therefore, estradiol causes stereologically detectable changes in the size and number of neurons in BMN AC.
Кључне речи:
estradiol / basomedial nucleus / amygdaloid complexИзвор:
Acta Veterinaria-Beograd, 1999, 49, 4, 231-238Издавач:
- Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Đelić, D AU - Lozanče, Olivera AU - Đelić, Ninoslav AU - Drekić, Dmitar PY - 1999 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/122 AB - The amygdaloid complex (AC) of rat brain is sensitive to sex steroids, especially during neonatal development. The aim of this investigation was to determine possible changes in neuron morphology of the basomedial nucleus (BMN) of the AC in female rats treated with estradiol. Two straining techniques were used: (1) standard histological staining with hematoxylin-eosin and (2) the Golgi method. Three types of neurons: pyramidal, fusiform and stellate were subjected to stereologic analaysis. Estradiol significantly increased the volume of neuronal soma of all three neuronal types at 16 and 90 days of age, whereas at day 38 changes were observed only in fusiform and stellate neurons. In addition, the volume of cell nuclei was increased but the number of neurons per unit area decreased at all experimental intervals examined. Therefore, estradiol causes stereologically detectable changes in the size and number of neurons in BMN AC. PB - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd T2 - Acta Veterinaria-Beograd T1 - Influence of estradiol on neurons of nucleus basomedialis in the amygdaloid complex of female rats VL - 49 IS - 4 SP - 231 EP - 238 UR - https://hdl.handle.net/21.15107/rcub_veterinar_122 ER -
@article{ author = "Đelić, D and Lozanče, Olivera and Đelić, Ninoslav and Drekić, Dmitar", year = "1999", abstract = "The amygdaloid complex (AC) of rat brain is sensitive to sex steroids, especially during neonatal development. The aim of this investigation was to determine possible changes in neuron morphology of the basomedial nucleus (BMN) of the AC in female rats treated with estradiol. Two straining techniques were used: (1) standard histological staining with hematoxylin-eosin and (2) the Golgi method. Three types of neurons: pyramidal, fusiform and stellate were subjected to stereologic analaysis. Estradiol significantly increased the volume of neuronal soma of all three neuronal types at 16 and 90 days of age, whereas at day 38 changes were observed only in fusiform and stellate neurons. In addition, the volume of cell nuclei was increased but the number of neurons per unit area decreased at all experimental intervals examined. Therefore, estradiol causes stereologically detectable changes in the size and number of neurons in BMN AC.", publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd", journal = "Acta Veterinaria-Beograd", title = "Influence of estradiol on neurons of nucleus basomedialis in the amygdaloid complex of female rats", volume = "49", number = "4", pages = "231-238", url = "https://hdl.handle.net/21.15107/rcub_veterinar_122" }
Đelić, D., Lozanče, O., Đelić, N.,& Drekić, D.. (1999). Influence of estradiol on neurons of nucleus basomedialis in the amygdaloid complex of female rats. in Acta Veterinaria-Beograd Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 49(4), 231-238. https://hdl.handle.net/21.15107/rcub_veterinar_122
Đelić D, Lozanče O, Đelić N, Drekić D. Influence of estradiol on neurons of nucleus basomedialis in the amygdaloid complex of female rats. in Acta Veterinaria-Beograd. 1999;49(4):231-238. https://hdl.handle.net/21.15107/rcub_veterinar_122 .
Đelić, D, Lozanče, Olivera, Đelić, Ninoslav, Drekić, Dmitar, "Influence of estradiol on neurons of nucleus basomedialis in the amygdaloid complex of female rats" in Acta Veterinaria-Beograd, 49, no. 4 (1999):231-238, https://hdl.handle.net/21.15107/rcub_veterinar_122 .