First report of Polycystic kidney disease occurrence in Persian cats in Serbia
2016
Аутори
Vučićević, MilošSlijepcević, Dajana
Davitkov, Darko
Avdalović, Vladimir
Aleksić-Kovačević, Sanja
Stevanović, Jevrosima
Stanimirović, Zoran
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Polycystic kidney disease (PKD) is an inherited autosomal disorder in cats, mostly diagnosed in Persian cats. Renal cysts can be diagnosed by ultrasound, but cats must be at least 16 weeks old. The goals of this study were to assess the occurrence of PKD in Serbia using a randomly selected group of Persian cats, to compare the diagnostic efficacy of ultrasound and genetic tests, and to measure haematological and selected biochemical parameters. We examined 70 cats of Persian breed, between 4 months and 8 years of age. Complete blood count and selected biochemical parameters were measured, renal ultrasound was performed. Swabs of the oral cavity were obtained for genetic testing. Percentage of PKD positive cats identified by genetic testing was 48.6%, whilst only 18.6% were detected through ultrasound. Animals that were polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) positive and ultrasound negative ranged from 4 months to 3.5 years. All haematological and ...biochemical parameters were within the the normal range values in all examined cats. Genetic methods proved to be the most effective for reliable and early diagnosis of PKD in Persian cats. DNA analysis can be used right after birth, and excludes the need for other diagnostic procedures, such as ultrasound.
Кључне речи:
DNA tests / PCR-RFLP / Persian cats / Polycystic kidney / disease / Serbia / UltrasoundИзвор:
Veterinaria Italiana, 2016, 52, 1, 51-56Издавач:
- Ist Zooprofilattico Sperimentale Abruzzo & Molise G Caporale-Izs A&M, Teramo
Финансирање / пројекти:
DOI: 10.12834/VetIt.599.2885.2
ISSN: 0505-401X
PubMed: 27033530
WoS: 000398726400007
Scopus: 2-s2.0-84964047888
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Vučićević, Miloš AU - Slijepcević, Dajana AU - Davitkov, Darko AU - Avdalović, Vladimir AU - Aleksić-Kovačević, Sanja AU - Stevanović, Jevrosima AU - Stanimirović, Zoran PY - 2016 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1411 AB - Polycystic kidney disease (PKD) is an inherited autosomal disorder in cats, mostly diagnosed in Persian cats. Renal cysts can be diagnosed by ultrasound, but cats must be at least 16 weeks old. The goals of this study were to assess the occurrence of PKD in Serbia using a randomly selected group of Persian cats, to compare the diagnostic efficacy of ultrasound and genetic tests, and to measure haematological and selected biochemical parameters. We examined 70 cats of Persian breed, between 4 months and 8 years of age. Complete blood count and selected biochemical parameters were measured, renal ultrasound was performed. Swabs of the oral cavity were obtained for genetic testing. Percentage of PKD positive cats identified by genetic testing was 48.6%, whilst only 18.6% were detected through ultrasound. Animals that were polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) positive and ultrasound negative ranged from 4 months to 3.5 years. All haematological and biochemical parameters were within the the normal range values in all examined cats. Genetic methods proved to be the most effective for reliable and early diagnosis of PKD in Persian cats. DNA analysis can be used right after birth, and excludes the need for other diagnostic procedures, such as ultrasound. PB - Ist Zooprofilattico Sperimentale Abruzzo & Molise G Caporale-Izs A&M, Teramo T2 - Veterinaria Italiana T1 - First report of Polycystic kidney disease occurrence in Persian cats in Serbia VL - 52 IS - 1 SP - 51 EP - 56 DO - 10.12834/VetIt.599.2885.2 ER -
@article{ author = "Vučićević, Miloš and Slijepcević, Dajana and Davitkov, Darko and Avdalović, Vladimir and Aleksić-Kovačević, Sanja and Stevanović, Jevrosima and Stanimirović, Zoran", year = "2016", abstract = "Polycystic kidney disease (PKD) is an inherited autosomal disorder in cats, mostly diagnosed in Persian cats. Renal cysts can be diagnosed by ultrasound, but cats must be at least 16 weeks old. The goals of this study were to assess the occurrence of PKD in Serbia using a randomly selected group of Persian cats, to compare the diagnostic efficacy of ultrasound and genetic tests, and to measure haematological and selected biochemical parameters. We examined 70 cats of Persian breed, between 4 months and 8 years of age. Complete blood count and selected biochemical parameters were measured, renal ultrasound was performed. Swabs of the oral cavity were obtained for genetic testing. Percentage of PKD positive cats identified by genetic testing was 48.6%, whilst only 18.6% were detected through ultrasound. Animals that were polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) positive and ultrasound negative ranged from 4 months to 3.5 years. All haematological and biochemical parameters were within the the normal range values in all examined cats. Genetic methods proved to be the most effective for reliable and early diagnosis of PKD in Persian cats. DNA analysis can be used right after birth, and excludes the need for other diagnostic procedures, such as ultrasound.", publisher = "Ist Zooprofilattico Sperimentale Abruzzo & Molise G Caporale-Izs A&M, Teramo", journal = "Veterinaria Italiana", title = "First report of Polycystic kidney disease occurrence in Persian cats in Serbia", volume = "52", number = "1", pages = "51-56", doi = "10.12834/VetIt.599.2885.2" }
Vučićević, M., Slijepcević, D., Davitkov, D., Avdalović, V., Aleksić-Kovačević, S., Stevanović, J.,& Stanimirović, Z.. (2016). First report of Polycystic kidney disease occurrence in Persian cats in Serbia. in Veterinaria Italiana Ist Zooprofilattico Sperimentale Abruzzo & Molise G Caporale-Izs A&M, Teramo., 52(1), 51-56. https://doi.org/10.12834/VetIt.599.2885.2
Vučićević M, Slijepcević D, Davitkov D, Avdalović V, Aleksić-Kovačević S, Stevanović J, Stanimirović Z. First report of Polycystic kidney disease occurrence in Persian cats in Serbia. in Veterinaria Italiana. 2016;52(1):51-56. doi:10.12834/VetIt.599.2885.2 .
Vučićević, Miloš, Slijepcević, Dajana, Davitkov, Darko, Avdalović, Vladimir, Aleksić-Kovačević, Sanja, Stevanović, Jevrosima, Stanimirović, Zoran, "First report of Polycystic kidney disease occurrence in Persian cats in Serbia" in Veterinaria Italiana, 52, no. 1 (2016):51-56, https://doi.org/10.12834/VetIt.599.2885.2 . .