Selected hematology ratios in cats with non-septic effusions highly suspected of feline infectious peritonitis
Аутори
Kopilović, AleksandarGvozdić, Dragan
Radaković, Milena
Spariosu, Kristina
Andrić, Nenad
Francuski Andrić, Jelena
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
In veterinary medicine, knowledge about hematologic ratios (neutrophil-to-lymphocyte
ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume-to-platelet
ratio (MPV/PLT)) is limited, particularly in cats. While the roles of these ratios have
been proven in oncology, systemic inflammation with or without systemic inflammatory
response syndrome (SIRS), and sepsis, information is lacking about their alterations in
non-septic effusions, like feline infectious peritonitis (FIP).
This study aimed to describe whether NLR, PLR, and MPV/PLT were changed and
whether they correlated with routine hematologic and biochemical parameters in 16
cats with non-septic effusions, highly suspected to be the effusive form of FIP without
SIRS, compared to nine clinically healthy cats.
The NLR was calculated as the absolute count of neutrophils divided by the absolute
count of lymphocytes, PLR by calculating the absolute platelet divided by the absolute
lymphocyte count, and MPV/PL...T by dividing mean platelet volume by absolute platelet
count.
The NLR, MPV, and MPV/PLT ratios were higher in cats with non-septic effusions
suspected to be FIP, but PLR did not differ, when compared to healthy cats. Correlation analysis did not show any association between the selected ratios and hematological and
biochemical parameters.
In the absence of leukocytosis, increased NLR could help us to confirm the presence
of systemic inflammation in cats with non-septic effusions indicative of FIP. However,
a high MPV/PLT ratio should be interpreted with caution, especially in cats.
Кључне речи:
inflammation / mean platelet volume-to-platelet ratio / neutrophil-tolymphocyte ratio / platelet-to-lymphocyte ratioИзвор:
Veterinarski Glasnik, 2023, 77, 2, 164-175Издавач:
- Beograd : Fakultet veterinarske medicine
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200143 (Универзитет у Београду, Факултет ветеринарске медицине) (RS-MESTD-inst-2020-200143)
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Kopilović, Aleksandar AU - Gvozdić, Dragan AU - Radaković, Milena AU - Spariosu, Kristina AU - Andrić, Nenad AU - Francuski Andrić, Jelena PY - 2023 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3442 AB - In veterinary medicine, knowledge about hematologic ratios (neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume-to-platelet ratio (MPV/PLT)) is limited, particularly in cats. While the roles of these ratios have been proven in oncology, systemic inflammation with or without systemic inflammatory response syndrome (SIRS), and sepsis, information is lacking about their alterations in non-septic effusions, like feline infectious peritonitis (FIP). This study aimed to describe whether NLR, PLR, and MPV/PLT were changed and whether they correlated with routine hematologic and biochemical parameters in 16 cats with non-septic effusions, highly suspected to be the effusive form of FIP without SIRS, compared to nine clinically healthy cats. The NLR was calculated as the absolute count of neutrophils divided by the absolute count of lymphocytes, PLR by calculating the absolute platelet divided by the absolute lymphocyte count, and MPV/PLT by dividing mean platelet volume by absolute platelet count. The NLR, MPV, and MPV/PLT ratios were higher in cats with non-septic effusions suspected to be FIP, but PLR did not differ, when compared to healthy cats. Correlation analysis did not show any association between the selected ratios and hematological and biochemical parameters. In the absence of leukocytosis, increased NLR could help us to confirm the presence of systemic inflammation in cats with non-septic effusions indicative of FIP. However, a high MPV/PLT ratio should be interpreted with caution, especially in cats. PB - Beograd : Fakultet veterinarske medicine T2 - Veterinarski Glasnik T1 - Selected hematology ratios in cats with non-septic effusions highly suspected of feline infectious peritonitis VL - 77 IS - 2 SP - 164 EP - 175 DO - 10.2298/VETGL230710008K ER -
@article{ author = "Kopilović, Aleksandar and Gvozdić, Dragan and Radaković, Milena and Spariosu, Kristina and Andrić, Nenad and Francuski Andrić, Jelena", year = "2023", abstract = "In veterinary medicine, knowledge about hematologic ratios (neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume-to-platelet ratio (MPV/PLT)) is limited, particularly in cats. While the roles of these ratios have been proven in oncology, systemic inflammation with or without systemic inflammatory response syndrome (SIRS), and sepsis, information is lacking about their alterations in non-septic effusions, like feline infectious peritonitis (FIP). This study aimed to describe whether NLR, PLR, and MPV/PLT were changed and whether they correlated with routine hematologic and biochemical parameters in 16 cats with non-septic effusions, highly suspected to be the effusive form of FIP without SIRS, compared to nine clinically healthy cats. The NLR was calculated as the absolute count of neutrophils divided by the absolute count of lymphocytes, PLR by calculating the absolute platelet divided by the absolute lymphocyte count, and MPV/PLT by dividing mean platelet volume by absolute platelet count. The NLR, MPV, and MPV/PLT ratios were higher in cats with non-septic effusions suspected to be FIP, but PLR did not differ, when compared to healthy cats. Correlation analysis did not show any association between the selected ratios and hematological and biochemical parameters. In the absence of leukocytosis, increased NLR could help us to confirm the presence of systemic inflammation in cats with non-septic effusions indicative of FIP. However, a high MPV/PLT ratio should be interpreted with caution, especially in cats.", publisher = "Beograd : Fakultet veterinarske medicine", journal = "Veterinarski Glasnik", title = "Selected hematology ratios in cats with non-septic effusions highly suspected of feline infectious peritonitis", volume = "77", number = "2", pages = "164-175", doi = "10.2298/VETGL230710008K" }
Kopilović, A., Gvozdić, D., Radaković, M., Spariosu, K., Andrić, N.,& Francuski Andrić, J.. (2023). Selected hematology ratios in cats with non-septic effusions highly suspected of feline infectious peritonitis. in Veterinarski Glasnik Beograd : Fakultet veterinarske medicine., 77(2), 164-175. https://doi.org/10.2298/VETGL230710008K
Kopilović A, Gvozdić D, Radaković M, Spariosu K, Andrić N, Francuski Andrić J. Selected hematology ratios in cats with non-septic effusions highly suspected of feline infectious peritonitis. in Veterinarski Glasnik. 2023;77(2):164-175. doi:10.2298/VETGL230710008K .
Kopilović, Aleksandar, Gvozdić, Dragan, Radaković, Milena, Spariosu, Kristina, Andrić, Nenad, Francuski Andrić, Jelena, "Selected hematology ratios in cats with non-septic effusions highly suspected of feline infectious peritonitis" in Veterinarski Glasnik, 77, no. 2 (2023):164-175, https://doi.org/10.2298/VETGL230710008K . .