Acute and subchronic exposure of the common carp (Cyprinus carpio) to herbicide S-metolachlor
Аутори
Rašković, BožidarPoleksić, Vesna
Vuković, Gorica
Špirović Trifunović, Bojana
Božić, Gavrilo
Ćupić Miladinović, Dejana
Marković, Zoran
Brkić, Dragica
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
S-metolachlor is one of the most frequently used herbicides worldwide. However, toxicity studies of this herbicide to aquatic organisms are scarce. In the present study, two experiments were conducted to test the effects of S-metolachlor on common carp, one of the most economically important fish species, with a distribution throughout the world: (1) 96 h acute semi-static toxicity test, aiming to determine LC50; (2) a subchronic semi-static test that lasted 28 days, in which juvenile carp were exposed to 3%, 8%, and 25% of previously determined LC50—0.5 mg·L−1, 1.4 mg·L−1, and 4.1 mg·L−1, respectively. Several biomarkers were employed to assess fish responses to toxicants. Blood biochemistry analysis and nuclear alterations of erythrocytes did not show any difference among experimental groups. Semi-quantitative histopathological analysis revealed mild alterations in the gills and liver, where oedema of secondary epithelium of gills and leukocyte infiltration in liver were significantl...y higher in fish exposed to 1.4 mg·L−1 and 4.1 mg·L−1. Histopathological indices in liver, as well as the total histopathological index, also showed significantly higher scores in the same groups. Bioconcentration factors of S-metolachlor ranged from 3.2 to 9.4, depending on the experimental group.
Кључне речи:
histopathology / micronucleus / blood biochemistry / erythrocytes / bioconcentrationИзвор:
Water, 2023, 15, 23, 4182-Издавач:
- MDPI
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200116 (Универзитет у Београду, Пољопривредни факултет) (RS-MESTD-inst-2020-200116)
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Rašković, Božidar AU - Poleksić, Vesna AU - Vuković, Gorica AU - Špirović Trifunović, Bojana AU - Božić, Gavrilo AU - Ćupić Miladinović, Dejana AU - Marković, Zoran AU - Brkić, Dragica PY - 2023 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3657 AB - S-metolachlor is one of the most frequently used herbicides worldwide. However, toxicity studies of this herbicide to aquatic organisms are scarce. In the present study, two experiments were conducted to test the effects of S-metolachlor on common carp, one of the most economically important fish species, with a distribution throughout the world: (1) 96 h acute semi-static toxicity test, aiming to determine LC50; (2) a subchronic semi-static test that lasted 28 days, in which juvenile carp were exposed to 3%, 8%, and 25% of previously determined LC50—0.5 mg·L−1, 1.4 mg·L−1, and 4.1 mg·L−1, respectively. Several biomarkers were employed to assess fish responses to toxicants. Blood biochemistry analysis and nuclear alterations of erythrocytes did not show any difference among experimental groups. Semi-quantitative histopathological analysis revealed mild alterations in the gills and liver, where oedema of secondary epithelium of gills and leukocyte infiltration in liver were significantly higher in fish exposed to 1.4 mg·L−1 and 4.1 mg·L−1. Histopathological indices in liver, as well as the total histopathological index, also showed significantly higher scores in the same groups. Bioconcentration factors of S-metolachlor ranged from 3.2 to 9.4, depending on the experimental group. PB - MDPI T2 - Water T1 - Acute and subchronic exposure of the common carp (Cyprinus carpio) to herbicide S-metolachlor VL - 15 IS - 23 SP - 4182 DO - https://doi.org/10.3390/w15234182 ER -
@article{ author = "Rašković, Božidar and Poleksić, Vesna and Vuković, Gorica and Špirović Trifunović, Bojana and Božić, Gavrilo and Ćupić Miladinović, Dejana and Marković, Zoran and Brkić, Dragica", year = "2023", abstract = "S-metolachlor is one of the most frequently used herbicides worldwide. However, toxicity studies of this herbicide to aquatic organisms are scarce. In the present study, two experiments were conducted to test the effects of S-metolachlor on common carp, one of the most economically important fish species, with a distribution throughout the world: (1) 96 h acute semi-static toxicity test, aiming to determine LC50; (2) a subchronic semi-static test that lasted 28 days, in which juvenile carp were exposed to 3%, 8%, and 25% of previously determined LC50—0.5 mg·L−1, 1.4 mg·L−1, and 4.1 mg·L−1, respectively. Several biomarkers were employed to assess fish responses to toxicants. Blood biochemistry analysis and nuclear alterations of erythrocytes did not show any difference among experimental groups. Semi-quantitative histopathological analysis revealed mild alterations in the gills and liver, where oedema of secondary epithelium of gills and leukocyte infiltration in liver were significantly higher in fish exposed to 1.4 mg·L−1 and 4.1 mg·L−1. Histopathological indices in liver, as well as the total histopathological index, also showed significantly higher scores in the same groups. Bioconcentration factors of S-metolachlor ranged from 3.2 to 9.4, depending on the experimental group.", publisher = "MDPI", journal = "Water", title = "Acute and subchronic exposure of the common carp (Cyprinus carpio) to herbicide S-metolachlor", volume = "15", number = "23", pages = "4182", doi = "https://doi.org/10.3390/w15234182" }
Rašković, B., Poleksić, V., Vuković, G., Špirović Trifunović, B., Božić, G., Ćupić Miladinović, D., Marković, Z.,& Brkić, D.. (2023). Acute and subchronic exposure of the common carp (Cyprinus carpio) to herbicide S-metolachlor. in Water MDPI., 15(23), 4182. https://doi.org/https://doi.org/10.3390/w15234182
Rašković B, Poleksić V, Vuković G, Špirović Trifunović B, Božić G, Ćupić Miladinović D, Marković Z, Brkić D. Acute and subchronic exposure of the common carp (Cyprinus carpio) to herbicide S-metolachlor. in Water. 2023;15(23):4182. doi:https://doi.org/10.3390/w15234182 .
Rašković, Božidar, Poleksić, Vesna, Vuković, Gorica, Špirović Trifunović, Bojana, Božić, Gavrilo, Ćupić Miladinović, Dejana, Marković, Zoran, Brkić, Dragica, "Acute and subchronic exposure of the common carp (Cyprinus carpio) to herbicide S-metolachlor" in Water, 15, no. 23 (2023):4182, https://doi.org/https://doi.org/10.3390/w15234182 . .