Chestnut tannin supplementation can improve immune response and kidney function in prepartum dairy cows
Аутори
Prodanović, RadišaNedić, Sreten
Bošnjaković, Dušan
Nedić, Svetlana
Jovanović, Ljubomir
Arsić, Sveta
Bojkovski, Jovan
Borozan, Sunčica
Kirovski, Danijela
Vujanac, Ivan
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Due to their antiketogenic and antioxidant effects, chestnut
tannins may offer a viable approach to manage the impaired immune and
renal functions in transition cows. This study aimed to investigate the effects of
dietary supplementation with chestnut tannins on haematological, biochemical
and antioxidant indices, as well as cortisol levels in prepartum dairy cows.
Forty multiparous Holstein cows were divided into two homogeneous groups
(n = 20): a control (CON), and an experimental group (CNT) receiving
20 g/day of chestnut tannins for the last 25 ± 2 days of pregnancy. Haematological
and biochemical indices, cortisol concentration and total antioxidant capacity
(T-AOC) were measured in blood samples collected 25 (day −25) and 5 days
(day −5) before the expected parturition. The addition of chestnut tannins
exerted no significant effect on red blood cells indices; however, white blood cell
(P = 0.02), lymphocyte (P = 0.05) and platelet (P < 0.01) counts were higher,
while... the neutrophil to lymphocyte ratio (P = 0.03) was lower on day −5 in the
CNT group compared to the CON group. Significantly higher values of T-AOC
(P = 0.03) and significantly lower levels of triglycerides (P = 0.03) and gammaglutamyl
transferase (P = 0.02) were also found in CNT compared to CON on
day −5. The improved haematological profile in CNT cows was accompanied
by lower serum creatinine concentration (P = 0.04), while total protein, calcium,
phosphorus and cortisol did not differ significantly between CNT and CON cows.
These data demonstrate that dietary chestnut tannin supplementation in a closeup
diet has antioxidant and anti-inflammatory effects, and could potentially mitigate
immune suppression and kidney dysfunction near parturition. Further research
should be conducted concerning the mechanisms underlying these responses.
Кључне речи:
chestnut tannins / creatinine / dairy cows / haematology / immune functionИзвор:
Journal of Animal and Feed Sciences, 2024, 33, 2, 185-192Издавач:
- Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences in Jabłonna (Poland)
- Kielanowski
Финансирање / пројекти:
- MitiMetCattle - Mitigation of methane production from dairy cattle farm by nutritive modulation of cow`s metabolism (RS-ScienceFundRS-Ideje-7750295)
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Prodanović, Radiša AU - Nedić, Sreten AU - Bošnjaković, Dušan AU - Nedić, Svetlana AU - Jovanović, Ljubomir AU - Arsić, Sveta AU - Bojkovski, Jovan AU - Borozan, Sunčica AU - Kirovski, Danijela AU - Vujanac, Ivan PY - 2024 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3784 AB - Due to their antiketogenic and antioxidant effects, chestnut tannins may offer a viable approach to manage the impaired immune and renal functions in transition cows. This study aimed to investigate the effects of dietary supplementation with chestnut tannins on haematological, biochemical and antioxidant indices, as well as cortisol levels in prepartum dairy cows. Forty multiparous Holstein cows were divided into two homogeneous groups (n = 20): a control (CON), and an experimental group (CNT) receiving 20 g/day of chestnut tannins for the last 25 ± 2 days of pregnancy. Haematological and biochemical indices, cortisol concentration and total antioxidant capacity (T-AOC) were measured in blood samples collected 25 (day −25) and 5 days (day −5) before the expected parturition. The addition of chestnut tannins exerted no significant effect on red blood cells indices; however, white blood cell (P = 0.02), lymphocyte (P = 0.05) and platelet (P < 0.01) counts were higher, while the neutrophil to lymphocyte ratio (P = 0.03) was lower on day −5 in the CNT group compared to the CON group. Significantly higher values of T-AOC (P = 0.03) and significantly lower levels of triglycerides (P = 0.03) and gammaglutamyl transferase (P = 0.02) were also found in CNT compared to CON on day −5. The improved haematological profile in CNT cows was accompanied by lower serum creatinine concentration (P = 0.04), while total protein, calcium, phosphorus and cortisol did not differ significantly between CNT and CON cows. These data demonstrate that dietary chestnut tannin supplementation in a closeup diet has antioxidant and anti-inflammatory effects, and could potentially mitigate immune suppression and kidney dysfunction near parturition. Further research should be conducted concerning the mechanisms underlying these responses. PB - Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences in Jabłonna (Poland) PB - Kielanowski T2 - Journal of Animal and Feed Sciences T1 - Chestnut tannin supplementation can improve immune response and kidney function in prepartum dairy cows VL - 33 IS - 2 SP - 185 EP - 192 DO - 10.22358/jafs/174065/2023 ER -
@article{ author = "Prodanović, Radiša and Nedić, Sreten and Bošnjaković, Dušan and Nedić, Svetlana and Jovanović, Ljubomir and Arsić, Sveta and Bojkovski, Jovan and Borozan, Sunčica and Kirovski, Danijela and Vujanac, Ivan", year = "2024", abstract = "Due to their antiketogenic and antioxidant effects, chestnut tannins may offer a viable approach to manage the impaired immune and renal functions in transition cows. This study aimed to investigate the effects of dietary supplementation with chestnut tannins on haematological, biochemical and antioxidant indices, as well as cortisol levels in prepartum dairy cows. Forty multiparous Holstein cows were divided into two homogeneous groups (n = 20): a control (CON), and an experimental group (CNT) receiving 20 g/day of chestnut tannins for the last 25 ± 2 days of pregnancy. Haematological and biochemical indices, cortisol concentration and total antioxidant capacity (T-AOC) were measured in blood samples collected 25 (day −25) and 5 days (day −5) before the expected parturition. The addition of chestnut tannins exerted no significant effect on red blood cells indices; however, white blood cell (P = 0.02), lymphocyte (P = 0.05) and platelet (P < 0.01) counts were higher, while the neutrophil to lymphocyte ratio (P = 0.03) was lower on day −5 in the CNT group compared to the CON group. Significantly higher values of T-AOC (P = 0.03) and significantly lower levels of triglycerides (P = 0.03) and gammaglutamyl transferase (P = 0.02) were also found in CNT compared to CON on day −5. The improved haematological profile in CNT cows was accompanied by lower serum creatinine concentration (P = 0.04), while total protein, calcium, phosphorus and cortisol did not differ significantly between CNT and CON cows. These data demonstrate that dietary chestnut tannin supplementation in a closeup diet has antioxidant and anti-inflammatory effects, and could potentially mitigate immune suppression and kidney dysfunction near parturition. Further research should be conducted concerning the mechanisms underlying these responses.", publisher = "Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences in Jabłonna (Poland), Kielanowski", journal = "Journal of Animal and Feed Sciences", title = "Chestnut tannin supplementation can improve immune response and kidney function in prepartum dairy cows", volume = "33", number = "2", pages = "185-192", doi = "10.22358/jafs/174065/2023" }
Prodanović, R., Nedić, S., Bošnjaković, D., Nedić, S., Jovanović, L., Arsić, S., Bojkovski, J., Borozan, S., Kirovski, D.,& Vujanac, I.. (2024). Chestnut tannin supplementation can improve immune response and kidney function in prepartum dairy cows. in Journal of Animal and Feed Sciences Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences in Jabłonna (Poland)., 33(2), 185-192. https://doi.org/10.22358/jafs/174065/2023
Prodanović R, Nedić S, Bošnjaković D, Nedić S, Jovanović L, Arsić S, Bojkovski J, Borozan S, Kirovski D, Vujanac I. Chestnut tannin supplementation can improve immune response and kidney function in prepartum dairy cows. in Journal of Animal and Feed Sciences. 2024;33(2):185-192. doi:10.22358/jafs/174065/2023 .
Prodanović, Radiša, Nedić, Sreten, Bošnjaković, Dušan, Nedić, Svetlana, Jovanović, Ljubomir, Arsić, Sveta, Bojkovski, Jovan, Borozan, Sunčica, Kirovski, Danijela, Vujanac, Ivan, "Chestnut tannin supplementation can improve immune response and kidney function in prepartum dairy cows" in Journal of Animal and Feed Sciences, 33, no. 2 (2024):185-192, https://doi.org/10.22358/jafs/174065/2023 . .