Immunomodulation induced by pretreatment with 6-hydroxydopamine in the rat
Апстракт
To produce chemical sympathectomy, Wistar rats were pretreated with 6-hydroxydopamine (6-OHDA), a substance known to produce general depletion of catecholamines from their stores. 6-OHDA was injected either intracerebroventricularly (i.c.v.) or intraperitoneally (i.p.) into animals immunized with bovine serum albumin, sheep red blood cells and guinea-pig spinal cord. The results obtained indicate that pretreatment with 6-OHDA, decrease the number of plaque-forming cells (PFC), severity of clinical signs of experimental allergic encephalomyelitis (EAE) and suppressed skin sensitivity reaction.
Кључне речи:
Catecholamines / Hydroxydopamines / Immune system / NorepinephrineИзвор:
Vojnosanitetski pregled, 1994, 51, 4 SUPPL., 13-16Издавач:
- Vojnomedicinska akademija - Institut za naučne informacije, Beograd
Колекције
Институција/група
Fakultet veterinarske medicineTY - CONF AU - Ćupić, Vitomir AU - Varagić, V. AU - Janković, D. PY - 1994 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/68 AB - To produce chemical sympathectomy, Wistar rats were pretreated with 6-hydroxydopamine (6-OHDA), a substance known to produce general depletion of catecholamines from their stores. 6-OHDA was injected either intracerebroventricularly (i.c.v.) or intraperitoneally (i.p.) into animals immunized with bovine serum albumin, sheep red blood cells and guinea-pig spinal cord. The results obtained indicate that pretreatment with 6-OHDA, decrease the number of plaque-forming cells (PFC), severity of clinical signs of experimental allergic encephalomyelitis (EAE) and suppressed skin sensitivity reaction. PB - Vojnomedicinska akademija - Institut za naučne informacije, Beograd C3 - Vojnosanitetski pregled T1 - Immunomodulation induced by pretreatment with 6-hydroxydopamine in the rat VL - 51 IS - 4 SUPPL. SP - 13 EP - 16 UR - https://hdl.handle.net/21.15107/rcub_veterinar_68 ER -
@conference{ author = "Ćupić, Vitomir and Varagić, V. and Janković, D.", year = "1994", abstract = "To produce chemical sympathectomy, Wistar rats were pretreated with 6-hydroxydopamine (6-OHDA), a substance known to produce general depletion of catecholamines from their stores. 6-OHDA was injected either intracerebroventricularly (i.c.v.) or intraperitoneally (i.p.) into animals immunized with bovine serum albumin, sheep red blood cells and guinea-pig spinal cord. The results obtained indicate that pretreatment with 6-OHDA, decrease the number of plaque-forming cells (PFC), severity of clinical signs of experimental allergic encephalomyelitis (EAE) and suppressed skin sensitivity reaction.", publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd", journal = "Vojnosanitetski pregled", title = "Immunomodulation induced by pretreatment with 6-hydroxydopamine in the rat", volume = "51", number = "4 SUPPL.", pages = "13-16", url = "https://hdl.handle.net/21.15107/rcub_veterinar_68" }
Ćupić, V., Varagić, V.,& Janković, D.. (1994). Immunomodulation induced by pretreatment with 6-hydroxydopamine in the rat. in Vojnosanitetski pregled Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 51(4 SUPPL.), 13-16. https://hdl.handle.net/21.15107/rcub_veterinar_68
Ćupić V, Varagić V, Janković D. Immunomodulation induced by pretreatment with 6-hydroxydopamine in the rat. in Vojnosanitetski pregled. 1994;51(4 SUPPL.):13-16. https://hdl.handle.net/21.15107/rcub_veterinar_68 .
Ćupić, Vitomir, Varagić, V., Janković, D., "Immunomodulation induced by pretreatment with 6-hydroxydopamine in the rat" in Vojnosanitetski pregled, 51, no. 4 SUPPL. (1994):13-16, https://hdl.handle.net/21.15107/rcub_veterinar_68 .