Oregano: A potential prophylactic treatment for the intestinal microbiota
2019
Autori
Bauer, Benjamin W.Radovanović, Anita
Willson, Nicky-Lee
Bajagai, Yadav Sharma
Thi, Thu Hao Van
Moore, Robert J.
Stanley, Dragana
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Prophylactic use of antibiotics in poultry diets has been identified as a problematic practice because of its potential to exacerbate the spread of antibiotic resistance to human pathogens. A range of countries have opted to completely ban the use of antibiotics in animal feed. The animal production industries are looking for alternative ways to effectively control pathogens while providing the performance benefits previously secured by antibiotics in feed. Here, we present evidence that oregano (Origanum vulgare) could be a potential alternative for pathogen control in the poultry industry. Broiler diets were supplemented with oregano powder (0%, 0.5%, 1%, and 2%) for six weeks. The capacity for pathogen control was estimated by microbiota profiling of the jejunum, ileum, and caecum content, and in the faeces, by 16S rRNA gene amplicon sequencing. The concentrations of short-chain fatty acids in the caecal content were also measured, as were villus/crypt parameters in the ileum. There... were no differences among treatments in weight gain, feed intake, or the concentration of short-chain fatty acids. The height, width, and the surface area of villi in the ileum were not influenced by oregano addition. However, 1% and 2% of oregano produced a significant increase in the villus height to crypt depth ratio. There were no visible histopathological changes in the liver in control and treated groups. Although oregano had no significant effect on overall microbial diversity and gross composition, some specific genera, like Proteus, Klebsiella and Staphylococcus, which include known pathogens, were reduced in relative abundance by oregano treatment. Bifidobacterium, recognized as a beneficial and probiotic genus, was also suppressed by the oregano treatment.
Ključne reči:
Food microbiology / Animal science / Microbiology / Public health / Gastrointestinal system / Oregano / Chicken / Microbiota / Antibiotic alternativeIzvor:
Heliyon, 2019, 5, 10, e02625-Izdavač:
- Elsevier Sci Ltd, Oxford
Finansiranje / projekti:
- Poultry CRC under the Australian Government's Cooperative Research Centres ProgramAustralian GovernmentDepartment of Industry, Innovation and ScienceCooperative Research Centres (CRC) Programme
DOI: 10.1016/j.heliyon.2019.e02625
ISSN: 2405-8440
PubMed: 31667426
WoS: 000494641300128
Scopus: 2-s2.0-85073031224
Kolekcije
Institucija/grupa
Fakultet veterinarske medicineTY - JOUR AU - Bauer, Benjamin W. AU - Radovanović, Anita AU - Willson, Nicky-Lee AU - Bajagai, Yadav Sharma AU - Thi, Thu Hao Van AU - Moore, Robert J. AU - Stanley, Dragana PY - 2019 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1763 AB - Prophylactic use of antibiotics in poultry diets has been identified as a problematic practice because of its potential to exacerbate the spread of antibiotic resistance to human pathogens. A range of countries have opted to completely ban the use of antibiotics in animal feed. The animal production industries are looking for alternative ways to effectively control pathogens while providing the performance benefits previously secured by antibiotics in feed. Here, we present evidence that oregano (Origanum vulgare) could be a potential alternative for pathogen control in the poultry industry. Broiler diets were supplemented with oregano powder (0%, 0.5%, 1%, and 2%) for six weeks. The capacity for pathogen control was estimated by microbiota profiling of the jejunum, ileum, and caecum content, and in the faeces, by 16S rRNA gene amplicon sequencing. The concentrations of short-chain fatty acids in the caecal content were also measured, as were villus/crypt parameters in the ileum. There were no differences among treatments in weight gain, feed intake, or the concentration of short-chain fatty acids. The height, width, and the surface area of villi in the ileum were not influenced by oregano addition. However, 1% and 2% of oregano produced a significant increase in the villus height to crypt depth ratio. There were no visible histopathological changes in the liver in control and treated groups. Although oregano had no significant effect on overall microbial diversity and gross composition, some specific genera, like Proteus, Klebsiella and Staphylococcus, which include known pathogens, were reduced in relative abundance by oregano treatment. Bifidobacterium, recognized as a beneficial and probiotic genus, was also suppressed by the oregano treatment. PB - Elsevier Sci Ltd, Oxford T2 - Heliyon T1 - Oregano: A potential prophylactic treatment for the intestinal microbiota VL - 5 IS - 10 SP - e02625 DO - 10.1016/j.heliyon.2019.e02625 ER -
@article{ author = "Bauer, Benjamin W. and Radovanović, Anita and Willson, Nicky-Lee and Bajagai, Yadav Sharma and Thi, Thu Hao Van and Moore, Robert J. and Stanley, Dragana", year = "2019", abstract = "Prophylactic use of antibiotics in poultry diets has been identified as a problematic practice because of its potential to exacerbate the spread of antibiotic resistance to human pathogens. A range of countries have opted to completely ban the use of antibiotics in animal feed. The animal production industries are looking for alternative ways to effectively control pathogens while providing the performance benefits previously secured by antibiotics in feed. Here, we present evidence that oregano (Origanum vulgare) could be a potential alternative for pathogen control in the poultry industry. Broiler diets were supplemented with oregano powder (0%, 0.5%, 1%, and 2%) for six weeks. The capacity for pathogen control was estimated by microbiota profiling of the jejunum, ileum, and caecum content, and in the faeces, by 16S rRNA gene amplicon sequencing. The concentrations of short-chain fatty acids in the caecal content were also measured, as were villus/crypt parameters in the ileum. There were no differences among treatments in weight gain, feed intake, or the concentration of short-chain fatty acids. The height, width, and the surface area of villi in the ileum were not influenced by oregano addition. However, 1% and 2% of oregano produced a significant increase in the villus height to crypt depth ratio. There were no visible histopathological changes in the liver in control and treated groups. Although oregano had no significant effect on overall microbial diversity and gross composition, some specific genera, like Proteus, Klebsiella and Staphylococcus, which include known pathogens, were reduced in relative abundance by oregano treatment. Bifidobacterium, recognized as a beneficial and probiotic genus, was also suppressed by the oregano treatment.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Heliyon", title = "Oregano: A potential prophylactic treatment for the intestinal microbiota", volume = "5", number = "10", pages = "e02625", doi = "10.1016/j.heliyon.2019.e02625" }
Bauer, B. W., Radovanović, A., Willson, N., Bajagai, Y. S., Thi, T. H. V., Moore, R. J.,& Stanley, D.. (2019). Oregano: A potential prophylactic treatment for the intestinal microbiota. in Heliyon Elsevier Sci Ltd, Oxford., 5(10), e02625. https://doi.org/10.1016/j.heliyon.2019.e02625
Bauer BW, Radovanović A, Willson N, Bajagai YS, Thi THV, Moore RJ, Stanley D. Oregano: A potential prophylactic treatment for the intestinal microbiota. in Heliyon. 2019;5(10):e02625. doi:10.1016/j.heliyon.2019.e02625 .
Bauer, Benjamin W., Radovanović, Anita, Willson, Nicky-Lee, Bajagai, Yadav Sharma, Thi, Thu Hao Van, Moore, Robert J., Stanley, Dragana, "Oregano: A potential prophylactic treatment for the intestinal microbiota" in Heliyon, 5, no. 10 (2019):e02625, https://doi.org/10.1016/j.heliyon.2019.e02625 . .