Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols
Само за регистроване кориснике
2021
Аутори
Mitrović, Marko JumakeCiraj-Bjelac, O.
Jovanović, Z.
Krstić, Nikola
Nikezic, D.
Krstić, D.
Živković, M.
Lazarević Macanović, Mirjana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The objective of this work was to assess absorbed doses in organs and tissues of a rabbit, following computed tomography (CT) examinations, using a dedicated 3D voxel model. Absorbed doses in relevant organs were calculated using the MCNP5 Monte Carlo software. Calculations were perfomed for two standard CT protocols, using tube voltages of 110 kVp and 130 kVp. Absorbed doses were calculated in 11 organs and tissues, i.e., skin, bones, brain, muscles, heart, lungs, liver, spleen, kidney, testicles, and fat tissue. The doses ranged from 15.3 to 28.3 mGy, and from 40.2 to 74.3 mGy, in the two investigated protocols. The organs that received the highest dose were bones and kidneys. In contrast, brain and spleen were organs that received the smallest doses. Doses in organs which are stretched along the body did not change significantly with distance. On the other hand, doses in organs which are localized in the body showed maximums and minimums. Using the voxel model, it is possible to cal...culate the dose distribution in the rabbit’s body after CT scans, and study the potential biological effects of CT doses in certain organs. The voxel model presented in this work can be used to calculated doses in all radiation experiments in which rabbits are used as experimental animals.
Кључне речи:
Absorbed dose / CT / MCNP5 / Rabbit / Voxel phantomИзвор:
Radiation and Environmental Biophysics, 2021Издавач:
- Springer
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200122 (Универзитет у Крагујевцу, Природно-математички факултет) (RS-MESTD-inst-2020-200122)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200143 (Универзитет у Београду, Факултет ветеринарске медицине) (RS-MESTD-inst-2020-200143)
DOI: 10.1007/s00411-021-00941-7
ISSN: 1432-2099
WoS: 000692971200002
Scopus: 2-s2.0-85114373465
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Mitrović, Marko Jumake AU - Ciraj-Bjelac, O. AU - Jovanović, Z. AU - Krstić, Nikola AU - Nikezic, D. AU - Krstić, D. AU - Živković, M. AU - Lazarević Macanović, Mirjana PY - 2021 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2218 AB - The objective of this work was to assess absorbed doses in organs and tissues of a rabbit, following computed tomography (CT) examinations, using a dedicated 3D voxel model. Absorbed doses in relevant organs were calculated using the MCNP5 Monte Carlo software. Calculations were perfomed for two standard CT protocols, using tube voltages of 110 kVp and 130 kVp. Absorbed doses were calculated in 11 organs and tissues, i.e., skin, bones, brain, muscles, heart, lungs, liver, spleen, kidney, testicles, and fat tissue. The doses ranged from 15.3 to 28.3 mGy, and from 40.2 to 74.3 mGy, in the two investigated protocols. The organs that received the highest dose were bones and kidneys. In contrast, brain and spleen were organs that received the smallest doses. Doses in organs which are stretched along the body did not change significantly with distance. On the other hand, doses in organs which are localized in the body showed maximums and minimums. Using the voxel model, it is possible to calculate the dose distribution in the rabbit’s body after CT scans, and study the potential biological effects of CT doses in certain organs. The voxel model presented in this work can be used to calculated doses in all radiation experiments in which rabbits are used as experimental animals. PB - Springer T2 - Radiation and Environmental Biophysics T1 - Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols DO - 10.1007/s00411-021-00941-7 ER -
@article{ author = "Mitrović, Marko Jumake and Ciraj-Bjelac, O. and Jovanović, Z. and Krstić, Nikola and Nikezic, D. and Krstić, D. and Živković, M. and Lazarević Macanović, Mirjana", year = "2021", abstract = "The objective of this work was to assess absorbed doses in organs and tissues of a rabbit, following computed tomography (CT) examinations, using a dedicated 3D voxel model. Absorbed doses in relevant organs were calculated using the MCNP5 Monte Carlo software. Calculations were perfomed for two standard CT protocols, using tube voltages of 110 kVp and 130 kVp. Absorbed doses were calculated in 11 organs and tissues, i.e., skin, bones, brain, muscles, heart, lungs, liver, spleen, kidney, testicles, and fat tissue. The doses ranged from 15.3 to 28.3 mGy, and from 40.2 to 74.3 mGy, in the two investigated protocols. The organs that received the highest dose were bones and kidneys. In contrast, brain and spleen were organs that received the smallest doses. Doses in organs which are stretched along the body did not change significantly with distance. On the other hand, doses in organs which are localized in the body showed maximums and minimums. Using the voxel model, it is possible to calculate the dose distribution in the rabbit’s body after CT scans, and study the potential biological effects of CT doses in certain organs. The voxel model presented in this work can be used to calculated doses in all radiation experiments in which rabbits are used as experimental animals.", publisher = "Springer", journal = "Radiation and Environmental Biophysics", title = "Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols", doi = "10.1007/s00411-021-00941-7" }
Mitrović, M. J., Ciraj-Bjelac, O., Jovanović, Z., Krstić, N., Nikezic, D., Krstić, D., Živković, M.,& Lazarević Macanović, M.. (2021). Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols. in Radiation and Environmental Biophysics Springer.. https://doi.org/10.1007/s00411-021-00941-7
Mitrović MJ, Ciraj-Bjelac O, Jovanović Z, Krstić N, Nikezic D, Krstić D, Živković M, Lazarević Macanović M. Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols. in Radiation and Environmental Biophysics. 2021;. doi:10.1007/s00411-021-00941-7 .
Mitrović, Marko Jumake, Ciraj-Bjelac, O., Jovanović, Z., Krstić, Nikola, Nikezic, D., Krstić, D., Živković, M., Lazarević Macanović, Mirjana, "Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols" in Radiation and Environmental Biophysics (2021), https://doi.org/10.1007/s00411-021-00941-7 . .