Quantitative and qualitative analysis of Ag-NOR in benign and malignant canine mammary gland tumors
Kvantitativna i kvalitativna analiza Ag-NOR kod benignih i malignih tumora mlečne žlezde kuja
Апстракт
In this retrospective study, quantitative and qualitative analyses of argyrophil nucleolar organizer regions (AgNORs) in 54 malignant and 18 benign canine mammary gland tumors were made. Statistical analysis showed a significant difference in the mean number of AgNORs per cell between benign and malignant tumors (p lt 0.01). There was no significant difference in the mean number of AgNORs per cell between complex carcinomas, simple carcinomas and carcinomas in mixed tumors (p>0.05), as well as between adenomas and benign mixed tumors (p>0.05). Six different patterns of AgNOR distribution were observed. Types I, II, III and in only two cases, type IV, were observed in benign tumors, while all six types were observed in malignant tumors. The predominant types in malignant tumors were III, IV, V and VI. Cell types II, III and IV were predominant in malignant tumors with 5.5-7 AgNORs per cell, while cell types V and VI were dominant in tumors with more than 7 AgNORs per cell.
U ovoj retrospektivnoj studiji izvršena je kvalitativna i kvantitativna analiza arigrofilnih organizatora nukleolusa (AgNORs), 54 maligna i 18 benignih tumora mlečne žlezde pasa. Uočene su statistički značajne razlike u prosečnom broju AgNORs po ćeliji između benignih i malignih tumora (p lt 0.01). Nisu dokazane statistički značajne razlike u prosečnom broju AgNORs po ćeliji između kompleksnih karcinoma, prostih karcinoma i karcinoma u mešovitom tumoru (p>0.05). Zapaženo je šest različitih tipova distribucije AgNORs. Tipovi I, II, III i samo u dva slučaja tip IV su uočeni kod benignih tumora, dok su kod malignih tumora uočeno svih šest tipova. Dominantni tipovi kod malignih tumora su III, IV, V and VI. Ćelije tipa II, III i IV dominiraju kod tumora kji imaju prosečno 5.5-7 AgNORs po ćeliji, dok tipovi V i VI su dominantni kod tumora koji imaju prosečno više od 7 AgNORs po ćeliji.
Кључне речи:
dog / mammary gland / tumors / AgNORИзвор:
Acta Veterinaria-Beograd, 2003, 53, 5-6, 353-360Издавач:
- Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
DOI: 10.2298/AVB0306353J
ISSN: 0567-8315
WoS: 000187620300007
Scopus: 2-s2.0-1642575079
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Jelesijević, Tomislav AU - Jovanović, Milijan AU - Knežević, Milijana AU - Aleksić-Kovačević, Sanja PY - 2003 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/264 AB - In this retrospective study, quantitative and qualitative analyses of argyrophil nucleolar organizer regions (AgNORs) in 54 malignant and 18 benign canine mammary gland tumors were made. Statistical analysis showed a significant difference in the mean number of AgNORs per cell between benign and malignant tumors (p lt 0.01). There was no significant difference in the mean number of AgNORs per cell between complex carcinomas, simple carcinomas and carcinomas in mixed tumors (p>0.05), as well as between adenomas and benign mixed tumors (p>0.05). Six different patterns of AgNOR distribution were observed. Types I, II, III and in only two cases, type IV, were observed in benign tumors, while all six types were observed in malignant tumors. The predominant types in malignant tumors were III, IV, V and VI. Cell types II, III and IV were predominant in malignant tumors with 5.5-7 AgNORs per cell, while cell types V and VI were dominant in tumors with more than 7 AgNORs per cell. AB - U ovoj retrospektivnoj studiji izvršena je kvalitativna i kvantitativna analiza arigrofilnih organizatora nukleolusa (AgNORs), 54 maligna i 18 benignih tumora mlečne žlezde pasa. Uočene su statistički značajne razlike u prosečnom broju AgNORs po ćeliji između benignih i malignih tumora (p lt 0.01). Nisu dokazane statistički značajne razlike u prosečnom broju AgNORs po ćeliji između kompleksnih karcinoma, prostih karcinoma i karcinoma u mešovitom tumoru (p>0.05). Zapaženo je šest različitih tipova distribucije AgNORs. Tipovi I, II, III i samo u dva slučaja tip IV su uočeni kod benignih tumora, dok su kod malignih tumora uočeno svih šest tipova. Dominantni tipovi kod malignih tumora su III, IV, V and VI. Ćelije tipa II, III i IV dominiraju kod tumora kji imaju prosečno 5.5-7 AgNORs po ćeliji, dok tipovi V i VI su dominantni kod tumora koji imaju prosečno više od 7 AgNORs po ćeliji. PB - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd T2 - Acta Veterinaria-Beograd T1 - Quantitative and qualitative analysis of Ag-NOR in benign and malignant canine mammary gland tumors T1 - Kvantitativna i kvalitativna analiza Ag-NOR kod benignih i malignih tumora mlečne žlezde kuja VL - 53 IS - 5-6 SP - 353 EP - 360 DO - 10.2298/AVB0306353J ER -
@article{ author = "Jelesijević, Tomislav and Jovanović, Milijan and Knežević, Milijana and Aleksić-Kovačević, Sanja", year = "2003", abstract = "In this retrospective study, quantitative and qualitative analyses of argyrophil nucleolar organizer regions (AgNORs) in 54 malignant and 18 benign canine mammary gland tumors were made. Statistical analysis showed a significant difference in the mean number of AgNORs per cell between benign and malignant tumors (p lt 0.01). There was no significant difference in the mean number of AgNORs per cell between complex carcinomas, simple carcinomas and carcinomas in mixed tumors (p>0.05), as well as between adenomas and benign mixed tumors (p>0.05). Six different patterns of AgNOR distribution were observed. Types I, II, III and in only two cases, type IV, were observed in benign tumors, while all six types were observed in malignant tumors. The predominant types in malignant tumors were III, IV, V and VI. Cell types II, III and IV were predominant in malignant tumors with 5.5-7 AgNORs per cell, while cell types V and VI were dominant in tumors with more than 7 AgNORs per cell., U ovoj retrospektivnoj studiji izvršena je kvalitativna i kvantitativna analiza arigrofilnih organizatora nukleolusa (AgNORs), 54 maligna i 18 benignih tumora mlečne žlezde pasa. Uočene su statistički značajne razlike u prosečnom broju AgNORs po ćeliji između benignih i malignih tumora (p lt 0.01). Nisu dokazane statistički značajne razlike u prosečnom broju AgNORs po ćeliji između kompleksnih karcinoma, prostih karcinoma i karcinoma u mešovitom tumoru (p>0.05). Zapaženo je šest različitih tipova distribucije AgNORs. Tipovi I, II, III i samo u dva slučaja tip IV su uočeni kod benignih tumora, dok su kod malignih tumora uočeno svih šest tipova. Dominantni tipovi kod malignih tumora su III, IV, V and VI. Ćelije tipa II, III i IV dominiraju kod tumora kji imaju prosečno 5.5-7 AgNORs po ćeliji, dok tipovi V i VI su dominantni kod tumora koji imaju prosečno više od 7 AgNORs po ćeliji.", publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd", journal = "Acta Veterinaria-Beograd", title = "Quantitative and qualitative analysis of Ag-NOR in benign and malignant canine mammary gland tumors, Kvantitativna i kvalitativna analiza Ag-NOR kod benignih i malignih tumora mlečne žlezde kuja", volume = "53", number = "5-6", pages = "353-360", doi = "10.2298/AVB0306353J" }
Jelesijević, T., Jovanović, M., Knežević, M.,& Aleksić-Kovačević, S.. (2003). Quantitative and qualitative analysis of Ag-NOR in benign and malignant canine mammary gland tumors. in Acta Veterinaria-Beograd Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 53(5-6), 353-360. https://doi.org/10.2298/AVB0306353J
Jelesijević T, Jovanović M, Knežević M, Aleksić-Kovačević S. Quantitative and qualitative analysis of Ag-NOR in benign and malignant canine mammary gland tumors. in Acta Veterinaria-Beograd. 2003;53(5-6):353-360. doi:10.2298/AVB0306353J .
Jelesijević, Tomislav, Jovanović, Milijan, Knežević, Milijana, Aleksić-Kovačević, Sanja, "Quantitative and qualitative analysis of Ag-NOR in benign and malignant canine mammary gland tumors" in Acta Veterinaria-Beograd, 53, no. 5-6 (2003):353-360, https://doi.org/10.2298/AVB0306353J . .