Radiological Investigation of Guinea Pig (Cavia porcellus) Lumbar Vertebral Morphology - A Biomechanical Aspect
Authors
Mitrović, Marko JumakeKitanović, Sara
Tatalović, Nikola
Todorović, Anastasija
Lazarević Macanović, Mirjana
Article (Published version)
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Numerous studies are based on the use of animal models; however, in bipedal andtetrapedal organisms there are significant differences in the biomechanics of the spinalcolumn, which can significantly impair the quality and applicability of the resultsobtained. The aim of this study is to obtain basic data on the morphometric parametersof guinea pig lumbar vertebrae, the analysis of which will indicate the location of thebiggest mechanical load. The lumbar vertebra morphometry test was performed bymeans of X-ray imageing obtained from 12 guinea pigs, with equal numbers of malesand females. The results of investigations show that guinea pig lumbar vertebrae havean irregular trapezoid geometry and that the measured body lengths of L4 and L5 arethe largest. The height parameters determined in the medial level showed that L4 hadthe most concave body. Moreover, L4 had the greatest depth of the spinal canal at thesame measurement level. Consequently, in guinea pigs, the greatest load is in the... L4region, unlike in humans, where, due to the axial load of the spinal column, the highestpressure is exerted on the last lumbar vertebrae.
Keywords:
biomechanics / guinea pig / lumbar spine / morphometry / radiologySource:
Acta Veterinaria, 2023, 73, 1, 55-70Publisher:
- Belgrade : Faculty of Veterinary Medicine
Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković') (RS-MESTD-inst-2020-200007)
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Fakultet veterinarske medicineTY - JOUR AU - Mitrović, Marko Jumake AU - Kitanović, Sara AU - Tatalović, Nikola AU - Todorović, Anastasija AU - Lazarević Macanović, Mirjana PY - 2023 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2730 AB - Numerous studies are based on the use of animal models; however, in bipedal andtetrapedal organisms there are significant differences in the biomechanics of the spinalcolumn, which can significantly impair the quality and applicability of the resultsobtained. The aim of this study is to obtain basic data on the morphometric parametersof guinea pig lumbar vertebrae, the analysis of which will indicate the location of thebiggest mechanical load. The lumbar vertebra morphometry test was performed bymeans of X-ray imageing obtained from 12 guinea pigs, with equal numbers of malesand females. The results of investigations show that guinea pig lumbar vertebrae havean irregular trapezoid geometry and that the measured body lengths of L4 and L5 arethe largest. The height parameters determined in the medial level showed that L4 hadthe most concave body. Moreover, L4 had the greatest depth of the spinal canal at thesame measurement level. Consequently, in guinea pigs, the greatest load is in the L4region, unlike in humans, where, due to the axial load of the spinal column, the highestpressure is exerted on the last lumbar vertebrae. PB - Belgrade : Faculty of Veterinary Medicine T2 - Acta Veterinaria T1 - Radiological Investigation of Guinea Pig (Cavia porcellus) Lumbar Vertebral Morphology - A Biomechanical Aspect VL - 73 IS - 1 SP - 55 EP - 70 DO - 10.2478/acve-2023-0005 ER -
@article{ author = "Mitrović, Marko Jumake and Kitanović, Sara and Tatalović, Nikola and Todorović, Anastasija and Lazarević Macanović, Mirjana", year = "2023", abstract = "Numerous studies are based on the use of animal models; however, in bipedal andtetrapedal organisms there are significant differences in the biomechanics of the spinalcolumn, which can significantly impair the quality and applicability of the resultsobtained. The aim of this study is to obtain basic data on the morphometric parametersof guinea pig lumbar vertebrae, the analysis of which will indicate the location of thebiggest mechanical load. The lumbar vertebra morphometry test was performed bymeans of X-ray imageing obtained from 12 guinea pigs, with equal numbers of malesand females. The results of investigations show that guinea pig lumbar vertebrae havean irregular trapezoid geometry and that the measured body lengths of L4 and L5 arethe largest. The height parameters determined in the medial level showed that L4 hadthe most concave body. Moreover, L4 had the greatest depth of the spinal canal at thesame measurement level. Consequently, in guinea pigs, the greatest load is in the L4region, unlike in humans, where, due to the axial load of the spinal column, the highestpressure is exerted on the last lumbar vertebrae.", publisher = "Belgrade : Faculty of Veterinary Medicine", journal = "Acta Veterinaria", title = "Radiological Investigation of Guinea Pig (Cavia porcellus) Lumbar Vertebral Morphology - A Biomechanical Aspect", volume = "73", number = "1", pages = "55-70", doi = "10.2478/acve-2023-0005" }
Mitrović, M. J., Kitanović, S., Tatalović, N., Todorović, A.,& Lazarević Macanović, M.. (2023). Radiological Investigation of Guinea Pig (Cavia porcellus) Lumbar Vertebral Morphology - A Biomechanical Aspect. in Acta Veterinaria Belgrade : Faculty of Veterinary Medicine., 73(1), 55-70. https://doi.org/10.2478/acve-2023-0005
Mitrović MJ, Kitanović S, Tatalović N, Todorović A, Lazarević Macanović M. Radiological Investigation of Guinea Pig (Cavia porcellus) Lumbar Vertebral Morphology - A Biomechanical Aspect. in Acta Veterinaria. 2023;73(1):55-70. doi:10.2478/acve-2023-0005 .
Mitrović, Marko Jumake, Kitanović, Sara, Tatalović, Nikola, Todorović, Anastasija, Lazarević Macanović, Mirjana, "Radiological Investigation of Guinea Pig (Cavia porcellus) Lumbar Vertebral Morphology - A Biomechanical Aspect" in Acta Veterinaria, 73, no. 1 (2023):55-70, https://doi.org/10.2478/acve-2023-0005 . .