Potential of wormwood and oak bark-based supplement in health improvement of Nosema ceranae-infected honey bees
Аутори
Glavinić, UrošJovanović, Nemanja M.
Dominiković, Nina
Lakić, Nada
Ćosić, Milivoje
Stevanović, Jevrosima
Stanimirović, Zoran
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Nosema ceranae, a microsporidian parasite, as one of the stressors that contribute to honey bee decline, has a significant negative impact on the longevity, productivity, and reproductive capacity of honey bee colonies. There are several different strategies for Nosema infection control, including natural-based and antibiotic-based products. In this study, we tested wormwood and oak bark-based supplement “Medenko forte” on survival, Nosema infection, oxidative stress, and expression of immune-related genes in artificially N. ceranae-infected bees. The results revealed a positive influence on the survival of Nosema-infected bees, irrespectively of the moment of supplement application (day 1, day 3, or day 6 after bee emergence), as well as reduction of Nosema loads and, consequently, Nosema-induced oxidative stress. Supplementation had no negative effects on bee immunity, but better anti-Nosema than immune-stimulating effects were affirmed based on expression levels of abaecin, defensin..., hymenoptaecin, apidaecin, and vitellogenin genes. In conclusion, the tested supplement „Medenko forte” has great potential in the health protection of Nosema-infected bees. However, further investigations need to be performed to elucidate its mechanisms of action.
Кључне речи:
honey bee / Nosema ceranae / wormwood / oak bark / anti-Nosema / oxidative stressИзвор:
Animals, 2024, 14, 8, 1195-Издавач:
- MDPI
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200143 (Универзитет у Београду, Факултет ветеринарске медицине) (RS-MESTD-inst-2020-200143)
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Glavinić, Uroš AU - Jovanović, Nemanja M. AU - Dominiković, Nina AU - Lakić, Nada AU - Ćosić, Milivoje AU - Stevanović, Jevrosima AU - Stanimirović, Zoran PY - 2024 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3836 AB - Nosema ceranae, a microsporidian parasite, as one of the stressors that contribute to honey bee decline, has a significant negative impact on the longevity, productivity, and reproductive capacity of honey bee colonies. There are several different strategies for Nosema infection control, including natural-based and antibiotic-based products. In this study, we tested wormwood and oak bark-based supplement “Medenko forte” on survival, Nosema infection, oxidative stress, and expression of immune-related genes in artificially N. ceranae-infected bees. The results revealed a positive influence on the survival of Nosema-infected bees, irrespectively of the moment of supplement application (day 1, day 3, or day 6 after bee emergence), as well as reduction of Nosema loads and, consequently, Nosema-induced oxidative stress. Supplementation had no negative effects on bee immunity, but better anti-Nosema than immune-stimulating effects were affirmed based on expression levels of abaecin, defensin, hymenoptaecin, apidaecin, and vitellogenin genes. In conclusion, the tested supplement „Medenko forte” has great potential in the health protection of Nosema-infected bees. However, further investigations need to be performed to elucidate its mechanisms of action. PB - MDPI T2 - Animals T1 - Potential of wormwood and oak bark-based supplement in health improvement of Nosema ceranae-infected honey bees VL - 14 IS - 8 SP - 1195 DO - 10.3390/ani14081195 ER -
@article{ author = "Glavinić, Uroš and Jovanović, Nemanja M. and Dominiković, Nina and Lakić, Nada and Ćosić, Milivoje and Stevanović, Jevrosima and Stanimirović, Zoran", year = "2024", abstract = "Nosema ceranae, a microsporidian parasite, as one of the stressors that contribute to honey bee decline, has a significant negative impact on the longevity, productivity, and reproductive capacity of honey bee colonies. There are several different strategies for Nosema infection control, including natural-based and antibiotic-based products. In this study, we tested wormwood and oak bark-based supplement “Medenko forte” on survival, Nosema infection, oxidative stress, and expression of immune-related genes in artificially N. ceranae-infected bees. The results revealed a positive influence on the survival of Nosema-infected bees, irrespectively of the moment of supplement application (day 1, day 3, or day 6 after bee emergence), as well as reduction of Nosema loads and, consequently, Nosema-induced oxidative stress. Supplementation had no negative effects on bee immunity, but better anti-Nosema than immune-stimulating effects were affirmed based on expression levels of abaecin, defensin, hymenoptaecin, apidaecin, and vitellogenin genes. In conclusion, the tested supplement „Medenko forte” has great potential in the health protection of Nosema-infected bees. However, further investigations need to be performed to elucidate its mechanisms of action.", publisher = "MDPI", journal = "Animals", title = "Potential of wormwood and oak bark-based supplement in health improvement of Nosema ceranae-infected honey bees", volume = "14", number = "8", pages = "1195", doi = "10.3390/ani14081195" }
Glavinić, U., Jovanović, N. M., Dominiković, N., Lakić, N., Ćosić, M., Stevanović, J.,& Stanimirović, Z.. (2024). Potential of wormwood and oak bark-based supplement in health improvement of Nosema ceranae-infected honey bees. in Animals MDPI., 14(8), 1195. https://doi.org/10.3390/ani14081195
Glavinić U, Jovanović NM, Dominiković N, Lakić N, Ćosić M, Stevanović J, Stanimirović Z. Potential of wormwood and oak bark-based supplement in health improvement of Nosema ceranae-infected honey bees. in Animals. 2024;14(8):1195. doi:10.3390/ani14081195 .
Glavinić, Uroš, Jovanović, Nemanja M., Dominiković, Nina, Lakić, Nada, Ćosić, Milivoje, Stevanović, Jevrosima, Stanimirović, Zoran, "Potential of wormwood and oak bark-based supplement in health improvement of Nosema ceranae-infected honey bees" in Animals, 14, no. 8 (2024):1195, https://doi.org/10.3390/ani14081195 . .