Evaluation of immunogenic properties of monovalent and polyvalent inactivated bovine virus diarrhea virus (BVDV) vaccines
Апстракт
This study is aimed at evaluating the immunogenicity of two inactivated (mono- and polyvalent) vaccines containing bovine virus diarrhea virus (BVDV) reference and field strains. Three experimental groups were formed: 10 calves vaccinated twice (days 1 and 28) subcutaneously (s/c) with 2 ml of inactivated polyvalent vaccine per animal (Group 1); 10 calves vaccinated twice (days 1 and 28) subcutaneously (s/c) with 2 ml of inactivated monovalent vaccine per animal (Group 2) and 9 unvaccinated calves (Control, Group C). Blood sera were obtained from immunized animals (standard procedure: on days 0, 14, 28, 42 and 56 post-immunization). Geometric mean titer (GMT) values for BVDV neutralizing antibodies were substantially higher in blood sera of calves receiving the inactivated monovalent vaccine. The immune response developed more rapidly in calves immunized with the monovalent vaccine.
Кључне речи:
Bovine virus diarrhea virus / immunogenic properties / inactivated vaccinesИзвор:
African Journal of Microbiology Research, 2011, 5, 17, 2422-2427Издавач:
- Academic Journals, Victoria Island
Финансирање / пројекти:
- Ministry of Education and Science of the Republic of Serbia
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Kurcubić, Vladimir AU - Milić, Nenad AU - Đoković, Radojica AU - Ilić, Zoran PY - 2011 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/770 AB - This study is aimed at evaluating the immunogenicity of two inactivated (mono- and polyvalent) vaccines containing bovine virus diarrhea virus (BVDV) reference and field strains. Three experimental groups were formed: 10 calves vaccinated twice (days 1 and 28) subcutaneously (s/c) with 2 ml of inactivated polyvalent vaccine per animal (Group 1); 10 calves vaccinated twice (days 1 and 28) subcutaneously (s/c) with 2 ml of inactivated monovalent vaccine per animal (Group 2) and 9 unvaccinated calves (Control, Group C). Blood sera were obtained from immunized animals (standard procedure: on days 0, 14, 28, 42 and 56 post-immunization). Geometric mean titer (GMT) values for BVDV neutralizing antibodies were substantially higher in blood sera of calves receiving the inactivated monovalent vaccine. The immune response developed more rapidly in calves immunized with the monovalent vaccine. PB - Academic Journals, Victoria Island T2 - African Journal of Microbiology Research T1 - Evaluation of immunogenic properties of monovalent and polyvalent inactivated bovine virus diarrhea virus (BVDV) vaccines VL - 5 IS - 17 SP - 2422 EP - 2427 UR - https://hdl.handle.net/21.15107/rcub_veterinar_770 ER -
@article{ author = "Kurcubić, Vladimir and Milić, Nenad and Đoković, Radojica and Ilić, Zoran", year = "2011", abstract = "This study is aimed at evaluating the immunogenicity of two inactivated (mono- and polyvalent) vaccines containing bovine virus diarrhea virus (BVDV) reference and field strains. Three experimental groups were formed: 10 calves vaccinated twice (days 1 and 28) subcutaneously (s/c) with 2 ml of inactivated polyvalent vaccine per animal (Group 1); 10 calves vaccinated twice (days 1 and 28) subcutaneously (s/c) with 2 ml of inactivated monovalent vaccine per animal (Group 2) and 9 unvaccinated calves (Control, Group C). Blood sera were obtained from immunized animals (standard procedure: on days 0, 14, 28, 42 and 56 post-immunization). Geometric mean titer (GMT) values for BVDV neutralizing antibodies were substantially higher in blood sera of calves receiving the inactivated monovalent vaccine. The immune response developed more rapidly in calves immunized with the monovalent vaccine.", publisher = "Academic Journals, Victoria Island", journal = "African Journal of Microbiology Research", title = "Evaluation of immunogenic properties of monovalent and polyvalent inactivated bovine virus diarrhea virus (BVDV) vaccines", volume = "5", number = "17", pages = "2422-2427", url = "https://hdl.handle.net/21.15107/rcub_veterinar_770" }
Kurcubić, V., Milić, N., Đoković, R.,& Ilić, Z.. (2011). Evaluation of immunogenic properties of monovalent and polyvalent inactivated bovine virus diarrhea virus (BVDV) vaccines. in African Journal of Microbiology Research Academic Journals, Victoria Island., 5(17), 2422-2427. https://hdl.handle.net/21.15107/rcub_veterinar_770
Kurcubić V, Milić N, Đoković R, Ilić Z. Evaluation of immunogenic properties of monovalent and polyvalent inactivated bovine virus diarrhea virus (BVDV) vaccines. in African Journal of Microbiology Research. 2011;5(17):2422-2427. https://hdl.handle.net/21.15107/rcub_veterinar_770 .
Kurcubić, Vladimir, Milić, Nenad, Đoković, Radojica, Ilić, Zoran, "Evaluation of immunogenic properties of monovalent and polyvalent inactivated bovine virus diarrhea virus (BVDV) vaccines" in African Journal of Microbiology Research, 5, no. 17 (2011):2422-2427, https://hdl.handle.net/21.15107/rcub_veterinar_770 .