Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts
2012
Аутори
Arsić, IvanaŽugić, Ana R.
Tadić, Vanja M.
Tasic-Kostov, Marija
Mišić, Dušan
Primorac, Marija
Runjaic-Antić, Dusanka
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Oleum Hyperici, the oil extract of St. Johns Wort (SJW), is one of the oldest folk remedies, traditionally used in the topical treatment of wounds, bruises, ulcers, cuts, burns, hemorrhoids and also as an antiseptic. Considering the advantageous characteristics of emulsion applications, in the present study we have formulated three O/W creams containing 15% (w/v) of SJW oil extract as an active ingredient. The aim was to estimate dermatological application of the prepared creams for the abovementioned indications. The extracts were prepared according to the prescriptions from traditional medicine, however with different vegetable oils used as an extractant, namely: Olive, palm and sunflower oil. The investigated O/W creams demonstrated significant antiinflammatory effects in an in vivo double-blind randomized study, using a sodium lauryl sulphate test. Both skin parameters assessed in the study (electrical capacitance and erythema index), were restored to the baseline value after a sev...en-day treatment with the tested creams. Almost all investigated SJW oil extracts and corresponding creams displayed the same antimicrobial activity against the most of the investigated microorganisms with obtained minimal inhibitory concentrations values of 1,280 mu g/mL, 2,560 mu g/mL or >2,560 mu g/mL.
Кључне речи:
St. John's Wort / oil extracts / sunflower / olive / palm oil / dermatological applicationИзвор:
Molecules, 2012, 17, 1, 275-294Издавач:
- MDPI, Basel
Финансирање / пројекти:
- Функционални физиолошки активни биљни материјали са додатом вредношћу за примену у фармацеутској и прехрамбеној индустрији (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45017)
DOI: 10.3390/molecules17010275
ISSN: 1420-3049
PubMed: 22205093
WoS: 000299535700018
Scopus: 2-s2.0-84856139555
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Arsić, Ivana AU - Žugić, Ana R. AU - Tadić, Vanja M. AU - Tasic-Kostov, Marija AU - Mišić, Dušan AU - Primorac, Marija AU - Runjaic-Antić, Dusanka PY - 2012 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/890 AB - Oleum Hyperici, the oil extract of St. Johns Wort (SJW), is one of the oldest folk remedies, traditionally used in the topical treatment of wounds, bruises, ulcers, cuts, burns, hemorrhoids and also as an antiseptic. Considering the advantageous characteristics of emulsion applications, in the present study we have formulated three O/W creams containing 15% (w/v) of SJW oil extract as an active ingredient. The aim was to estimate dermatological application of the prepared creams for the abovementioned indications. The extracts were prepared according to the prescriptions from traditional medicine, however with different vegetable oils used as an extractant, namely: Olive, palm and sunflower oil. The investigated O/W creams demonstrated significant antiinflammatory effects in an in vivo double-blind randomized study, using a sodium lauryl sulphate test. Both skin parameters assessed in the study (electrical capacitance and erythema index), were restored to the baseline value after a seven-day treatment with the tested creams. Almost all investigated SJW oil extracts and corresponding creams displayed the same antimicrobial activity against the most of the investigated microorganisms with obtained minimal inhibitory concentrations values of 1,280 mu g/mL, 2,560 mu g/mL or >2,560 mu g/mL. PB - MDPI, Basel T2 - Molecules T1 - Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts VL - 17 IS - 1 SP - 275 EP - 294 DO - 10.3390/molecules17010275 ER -
@article{ author = "Arsić, Ivana and Žugić, Ana R. and Tadić, Vanja M. and Tasic-Kostov, Marija and Mišić, Dušan and Primorac, Marija and Runjaic-Antić, Dusanka", year = "2012", abstract = "Oleum Hyperici, the oil extract of St. Johns Wort (SJW), is one of the oldest folk remedies, traditionally used in the topical treatment of wounds, bruises, ulcers, cuts, burns, hemorrhoids and also as an antiseptic. Considering the advantageous characteristics of emulsion applications, in the present study we have formulated three O/W creams containing 15% (w/v) of SJW oil extract as an active ingredient. The aim was to estimate dermatological application of the prepared creams for the abovementioned indications. The extracts were prepared according to the prescriptions from traditional medicine, however with different vegetable oils used as an extractant, namely: Olive, palm and sunflower oil. The investigated O/W creams demonstrated significant antiinflammatory effects in an in vivo double-blind randomized study, using a sodium lauryl sulphate test. Both skin parameters assessed in the study (electrical capacitance and erythema index), were restored to the baseline value after a seven-day treatment with the tested creams. Almost all investigated SJW oil extracts and corresponding creams displayed the same antimicrobial activity against the most of the investigated microorganisms with obtained minimal inhibitory concentrations values of 1,280 mu g/mL, 2,560 mu g/mL or >2,560 mu g/mL.", publisher = "MDPI, Basel", journal = "Molecules", title = "Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts", volume = "17", number = "1", pages = "275-294", doi = "10.3390/molecules17010275" }
Arsić, I., Žugić, A. R., Tadić, V. M., Tasic-Kostov, M., Mišić, D., Primorac, M.,& Runjaic-Antić, D.. (2012). Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts. in Molecules MDPI, Basel., 17(1), 275-294. https://doi.org/10.3390/molecules17010275
Arsić I, Žugić AR, Tadić VM, Tasic-Kostov M, Mišić D, Primorac M, Runjaic-Antić D. Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts. in Molecules. 2012;17(1):275-294. doi:10.3390/molecules17010275 .
Arsić, Ivana, Žugić, Ana R., Tadić, Vanja M., Tasic-Kostov, Marija, Mišić, Dušan, Primorac, Marija, Runjaic-Antić, Dusanka, "Estimation of Dermatological Application of Creams with St. John s Wort Oil Extracts" in Molecules, 17, no. 1 (2012):275-294, https://doi.org/10.3390/molecules17010275 . .