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Cytogenetic analysis of the effects of epinephrine on cultured human lymphocytes / Citogenetička analiza dejstva adrenalina na humane limfocite u kulturi
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2003)
Epinephrine can modulate mitotic activity of normal and malignant cells and exhibit genotoxic potential in some test-systems. It is assumed that metabolic conversion of phenolic groups in the catechol ring of epinephrine ...
Monitoring of mitotic index and frequency of micronuclei in evaluation of genotoxic potential of fumagillin (dicyclohexylamine) in vivo / Praćenje mitotskog indeksa i učestalosti mikronukleusa u funkciji procene genotoksičnog potencijala fumagilina (dicikloheksilamina) in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2006)
Fumagillin (dicyclohexylamine) is a natural antibiotic, secreted by Aspergillus fumigatus. It is used in veterinary medicine against microsporidiosis in bees and fish, as well as in human medicine for the treatment of ...
Frequency of chromosomal aberrations in the evaluation of genotoxic potential of dicyclohexylamine (fumagillin) in vivo / Učestalost hromozomskih aberacija u funkciji evaluacije genotoksičnog potencijala fumagilina in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2006)
Dicyclohexylamine (fumagillin), as an antibiotic produced by fermentation of Aspergillus fumigatus, is used in human medicine for the treatment of intestinal microsporidiosis in patients with HIV infection, intestinal ...
Fumagillin-induced chromosome aberrations in mouse bone-marrow cells / Hromozomske aberacije prouzrokovane fumagilinom u ćelijama kostne srži miša
(Srpsko biološko društvo, Beograd, i dr., 2010)
The genotoxicity of fumagillin was evaluated assessing the mitotic index and chromosome aberrations in mouse bone-marrow cells. Mice were given fumagillin orally in doses 5, 10 and 20 mg/kg bw. All doses significantly (p ...
Genotoxicity potential of 8-Cl-cyclic adenosine monophosphate assessed with cytogenetic tests in vivo
(Elsevier Science Inc, New York, 2004)
Background. Growth-modulating noncytotoxic activity of 8-chloro-adenosine 3,5-cyclic monophosphate (8-Cl-cAMP) showed inhibitory effect on growth of a wide variety of cancer cell lines in vitro and in vivo. To assess ...
Evaluation of the genotoxic effects of thyroxine using in vivo cytogenetic test on Swiss albino mice / Evaluacija genotoksičnih efekata tiroksina primenom in vivo citogenetičkog testa na Swiss albino miševima
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2007)
Thyroid hormones enhance aerobic metabolism favoring oxidative stress which may lead to covalent damage of various molecules including DNA. Previous investigations revealed that thyroid hormones induce DNA damage on human ...
The genotoxic effects of alphachlorhydrin in BALB/C laboratory mice
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 1999)
The genotoxic properties of different doses (7,5, 15 and 30 mg/kg body mass) of alphachlorchydrin were investigated in vivo in BALB/C mice and in vitro using cell cultures. Thus, mouse bone marrow cells were examined after ...
Genotoxicity of the anticoccidial agent salinomycin
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 1998)
This report presents an analysis of genotoxic effects of the ionophoric antibiotic salinomycin commonly used in the control of coccidiosis. Mutagenic properties were determined, after application of increasing doses to ...
Effects of photopolymerisation on genotoxicity of composite adhesives in the comet assay
(Društvo genetičara Srbije, Beograd, 2016)
Certain in vivo studies have shown that the application of adhesives directly onto the open pulp or on a thin layer of dentin causes inflammation and pulpal abscesses. This reaction is related to toxic effects of monomers ...
Examination of Carbadox genotoxicity in vitro and in vivo / Ispitivanje genotoksičnog efekta Carbadoxa in vitro i in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2000)
Due to its bactericidal activity Carbadox is used for treatment of swine dysentery and salmonellosis. Also, it can be used as a factor for growth stimulation. Carbadox is the only drug for certain health problems in swine ...