Emerging novel porcine parvoviruses in Europe: origin, evolution, phylodynamics and phylogeography
2013
Autori
Cadar, DanielLorincz, Marta
Kiss, Timea
Novosel, Dinko
Podgorska, Katarzyna
Becskei, Zsolt
Tuboly, Tamas
Csagola, Attila
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
To elucidate the spatiotemporal phylodynamics, dispersion and evolutionary processes underlying the emergence of novel porcine parvovirus 2 (PPV2), PPV3 and PPV4 species, we analysed all available complete capsid genes, together with ours, obtained in Europe. Bayesian phylogeography indicates that Romania (PPV2 and PPV4) and Croatia (PPV3) are the most likely ancestral areas from which PPVs have subsequently spread to other European countries and regions. The timescale of our reconstruction supported a relatively recent history of the currently circulating novel PPV species (1920s to 1980s) in the domestic or sylvatic host. While PPV2 strains exhibited a large genetic exchange characterized by significant recombination and gene flow between distinct regions and hosts, PPV3 and PPV4 showed a diversification reflected by the accumulation of geographically structured polymorphisms. The RNA-like evolutionary rates detected inter- and intrahost recombination and the positive selection sites... provided evidence that the PPV2-4 capsid gene plays a prominent role in host adaptation.
Izvor:
Journal of General Virology, 2013, 94, 2330-2337Izdavač:
- Soc General Microbiology, Reading
Finansiranje / projekti:
- OTKAOrszagos Tudomanyos Kutatasi Alapprogramok (OTKA) [PD/100405]
- KTIA-AIK grant of the Hungarian Government
- Janos Bolyai Research Scholarship of the Hungarian Academy of SciencesHungarian Academy of Sciences
- Balassi Institute-Hungarian Scholarship Board Office
DOI: 10.1099/vir.0.055129-0
ISSN: 0022-1317
PubMed: 23884365
WoS: 000326215000019
Scopus: 2-s2.0-84884187940
Kolekcije
Institucija/grupa
Fakultet veterinarske medicineTY - JOUR AU - Cadar, Daniel AU - Lorincz, Marta AU - Kiss, Timea AU - Novosel, Dinko AU - Podgorska, Katarzyna AU - Becskei, Zsolt AU - Tuboly, Tamas AU - Csagola, Attila PY - 2013 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1001 AB - To elucidate the spatiotemporal phylodynamics, dispersion and evolutionary processes underlying the emergence of novel porcine parvovirus 2 (PPV2), PPV3 and PPV4 species, we analysed all available complete capsid genes, together with ours, obtained in Europe. Bayesian phylogeography indicates that Romania (PPV2 and PPV4) and Croatia (PPV3) are the most likely ancestral areas from which PPVs have subsequently spread to other European countries and regions. The timescale of our reconstruction supported a relatively recent history of the currently circulating novel PPV species (1920s to 1980s) in the domestic or sylvatic host. While PPV2 strains exhibited a large genetic exchange characterized by significant recombination and gene flow between distinct regions and hosts, PPV3 and PPV4 showed a diversification reflected by the accumulation of geographically structured polymorphisms. The RNA-like evolutionary rates detected inter- and intrahost recombination and the positive selection sites provided evidence that the PPV2-4 capsid gene plays a prominent role in host adaptation. PB - Soc General Microbiology, Reading T2 - Journal of General Virology T1 - Emerging novel porcine parvoviruses in Europe: origin, evolution, phylodynamics and phylogeography VL - 94 SP - 2330 EP - 2337 DO - 10.1099/vir.0.055129-0 ER -
@article{ author = "Cadar, Daniel and Lorincz, Marta and Kiss, Timea and Novosel, Dinko and Podgorska, Katarzyna and Becskei, Zsolt and Tuboly, Tamas and Csagola, Attila", year = "2013", abstract = "To elucidate the spatiotemporal phylodynamics, dispersion and evolutionary processes underlying the emergence of novel porcine parvovirus 2 (PPV2), PPV3 and PPV4 species, we analysed all available complete capsid genes, together with ours, obtained in Europe. Bayesian phylogeography indicates that Romania (PPV2 and PPV4) and Croatia (PPV3) are the most likely ancestral areas from which PPVs have subsequently spread to other European countries and regions. The timescale of our reconstruction supported a relatively recent history of the currently circulating novel PPV species (1920s to 1980s) in the domestic or sylvatic host. While PPV2 strains exhibited a large genetic exchange characterized by significant recombination and gene flow between distinct regions and hosts, PPV3 and PPV4 showed a diversification reflected by the accumulation of geographically structured polymorphisms. The RNA-like evolutionary rates detected inter- and intrahost recombination and the positive selection sites provided evidence that the PPV2-4 capsid gene plays a prominent role in host adaptation.", publisher = "Soc General Microbiology, Reading", journal = "Journal of General Virology", title = "Emerging novel porcine parvoviruses in Europe: origin, evolution, phylodynamics and phylogeography", volume = "94", pages = "2330-2337", doi = "10.1099/vir.0.055129-0" }
Cadar, D., Lorincz, M., Kiss, T., Novosel, D., Podgorska, K., Becskei, Z., Tuboly, T.,& Csagola, A.. (2013). Emerging novel porcine parvoviruses in Europe: origin, evolution, phylodynamics and phylogeography. in Journal of General Virology Soc General Microbiology, Reading., 94, 2330-2337. https://doi.org/10.1099/vir.0.055129-0
Cadar D, Lorincz M, Kiss T, Novosel D, Podgorska K, Becskei Z, Tuboly T, Csagola A. Emerging novel porcine parvoviruses in Europe: origin, evolution, phylodynamics and phylogeography. in Journal of General Virology. 2013;94:2330-2337. doi:10.1099/vir.0.055129-0 .
Cadar, Daniel, Lorincz, Marta, Kiss, Timea, Novosel, Dinko, Podgorska, Katarzyna, Becskei, Zsolt, Tuboly, Tamas, Csagola, Attila, "Emerging novel porcine parvoviruses in Europe: origin, evolution, phylodynamics and phylogeography" in Journal of General Virology, 94 (2013):2330-2337, https://doi.org/10.1099/vir.0.055129-0 . .