Приказ основних података о документу

dc.creatorPetrujkić, Branko
dc.creatorSedej, Ivana
dc.creatorBeier, Ross C.
dc.creatorAnderson, Robin C.
dc.creatorHarvey, Roger B.
dc.creatorEpps, Sharon V. R.
dc.creatorStipanović, Robert D.
dc.creatorKrueger, Nathan A.
dc.creatorNisbet, David J.
dc.date.accessioned2020-06-03T13:42:40Z
dc.date.available2020-06-03T13:42:40Z
dc.date.issued2013
dc.identifier.issn0021-8561
dc.identifier.urihttps://vet-erinar.vet.bg.ac.rs/handle/123456789/1016
dc.description.abstractFood-producing animals are reservoirs of Campylobacter, a leading bacterial cause of human foodborne illness. The natural product thymol can reduce the survivability of Campylobacter, but its rapid absorption in the proximal gastrointestinal tract may preclude its use as a feed additive to reduce intestinal colonization of these pathogens. This work examined the ex vivo absorption of thymol and thymol-beta-D-glucopyranoside in everted porcine jejunal segments, as the latter was hypothesized to be more resistant to absorption. A modified gas chromatography and extraction method was developed to determine 1.0-500 mg/L thymol. From 1 and 3 mM solutions, 0.293 +/- 0.04 and 0.898 +/- 0.212 mM thymol, respectively, p = 0.0347, were absorbed, and 0.125 +/- 0.041 and 0.317 +/- 0.143 mM thymol-beta-D-glucopyranoside, respectively, p = 0.0892, were absorbed. Results indicate that thymol-beta-D-glucopyranoside was absorbed 2.3 to 2.8 times less effectively than thymol, thus providing evidence that thymol-beta-D-glucopyranoside may potentially be used as a feed additive to transport thymol to the piglet lower gut.en
dc.publisherAmer Chemical Soc, Washington
dc.relationNorman Borlaug Institute, USA
dc.relationUSDA, ARS, SPARC, College Station, TX, USA
dc.relationSerbian Ministry of Education and Science, Belgrade, Serbia
dc.rightsrestrictedAccess
dc.sourceJournal of Agricultural and Food Chemistry
dc.subjectgas chromatographyen
dc.subjectpiglet everted small intestineen
dc.subjectthymolen
dc.subjectthymol-beta-D-glucopyranosideen
dc.titleEx Vivo Absorption of Thymol and Thymol-beta-D-glucopyranoside in Piglet Everted Jejunal Segmentsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractAндерсон, Робин Ц.; Петрујкић, Бранко; Круегер, Натхан A.; Стипановић, Роберт Д.; Еппс, Схарон В. Р.; Нисбет, Давид Ј.; Харвеy, Рогер Б.; Беиер, Росс Ц.; Седеј, Ивана;
dc.citation.volume61
dc.citation.issue15
dc.citation.spage3757
dc.citation.epage3762
dc.citation.other61(15): 3757-3762
dc.citation.rankaM21
dc.identifier.wos000317872700021
dc.identifier.doi10.1021/jf401013a
dc.identifier.pmid23551201
dc.identifier.scopus2-s2.0-84876462670
dc.type.versionpublishedVersion


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Приказ основних података о документу