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Status serumskih proteina brojlera hranjenih obrocima sa rastućim koncentracijama ohratoksina A

dc.creatorNedeljković-Trailović, Jelena
dc.creatorTrailović, Saša
dc.creatorDimitrijević, Mirjana
dc.creatorIlić, Vojislav
dc.date.accessioned2020-06-03T13:43:12Z
dc.date.available2020-06-03T13:43:12Z
dc.date.issued2013
dc.identifier.issn0567-8315
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/1024
dc.description.abstractThe 42-day long study was performed on a total number of 48 Hybro broilers divided into four groups. After the pre-experimental period of 14 days, 3 experimental groups of broilers (n=12) were formed and fed diets that contained 0.5, 1.0 and 1.5 mg/kg ochratoxin A (OTA) during the next seven consecutive days. In the same period, the control group of broilers was fed a diet with no toxin added. After the period of toxin addition, blood samples were taken from 6 animals in each group. The remaining animals (n=6) from the control and experimental groups were fed diets without OTA until the 42nd day of the study, when the blood samples were taken again. The total level of blood serum proteins was affected by treatment with different doses of OTA, but a significant and dose dependent increase of albumins together with a decrease of γ-globulin fraction was established. A/G ratio (Albumine/Globuline) suggested that the globulins were the dominant protein fraction in the blood serum samples obtained from all the broilers included in this study. The concentrations of α- and β- globulin in the serum were within physiological limits, but the concentration of γ-globulins significantly decreased. It can be concluded that the increasing dietary OTA levels (0.5, 1.0 and 1.5 mg/kg) had dose-dependent cumulative effect on blood serum proteins status in broilers, and the effect lasts even after the withdrawal of OTA from the feed.en
dc.description.abstractIspitivanje je trajalo 42 dan na ukupno 48 brojlera podeljenih u četiri jednake grupe. Preeksperimentalni period trajao je 14 dana, nakon čega su životinje tri ogledne grupe tokom sedam dana hranjene obrocma koji su sadržali 0,5, 1,0 i 1,5 mg ohratoksina A (OTA) u 1kg hrane. Brojleri kontrolne grupe u toku eksperimentalnog perioda hranjeni su hranom bez dodatka toksina. Posle sedam dana tretmana uzimani su uzorci krvi od po šest životinja iz svake grupe (kontrolne i eksperimentalnih). Preostale životinje hranjene su obrocima bez toksina do 42. dana ogleda, nakon čega je krv uzorkovana i od njih. Koncentracija ukupnih proteina plazme bila je promenjena u zavisnosti od koncentracije OTA koji su brojleri dobijali hranom. Takođe je zabeleženo značajno i dozno-zavisno povećanje koncentracije albumina sa snižavanjem koncentracije gama-globulinske frakcije u serumu. Albulin/Globulin odnos (A/G odnos) ukazuje da su globulini bili dominantna frakcija proteina kod svih brojlera u ispitivanju. Koncentracija alfa i beta-globulina u serumu brojlera kretala se u fiziološkim granicama dok je koncentracija gamaglobulina bila značajno snižena. Može se zaključiti da rastuće koncentracije OTA u hrani brojlera ispoljavaju dozno-zavistan kumulativni efekt na status serumskih proteina. Ovaj efekat ostaje i posle prestanka dodavanja toksina u hranu.sr
dc.publisherUniverzitet u Beogradu - Fakultet veterinarske medicine, Beograd
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31087/RS//
dc.rightsopenAccess
dc.sourceActa veterinaria - Beograd
dc.subjectA/G ratioen
dc.subjectbroileren
dc.subjectochratoxin Aen
dc.subjectpoultryen
dc.subjectproteinsen
dc.titleBlood serum protein status in broilers fed with increasing concentrations of ochratoxin Aen
dc.titleStatus serumskih proteina brojlera hranjenih obrocima sa rastućim koncentracijama ohratoksina Asr
dc.typearticle
dc.rights.licenseARR
dcterms.abstractДимитријевић, Мирјана; Траиловић, Саша; Недељковић-Траиловић, Јелена; Илић, Војислав; Статус серумских протеина бројлера храњених оброцима са растућим концентрацијама охратоксина A; Статус серумских протеина бројлера храњених оброцима са растућим концентрацијама охратоксина A;
dc.citation.volume63
dc.citation.issue1
dc.citation.spage77
dc.citation.epage88
dc.citation.other63(1): 77-88
dc.citation.rankM23
dc.identifier.wos000316523900007
dc.identifier.doi10.2298/AVB1301077N
dc.identifier.scopus2-s2.0-84879101082
dc.identifier.fulltexthttp://veterinar.vet.bg.ac.rs/bitstream/id/21/1023.pdf
dc.identifier.rcubconv_794
dc.type.versionpublishedVersion


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