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dc.creatorCenić-Milošević, Desanka
dc.creatorTambur, Zoran
dc.creatorIvancajić, S.
dc.creatorStanojković, Tatjana
dc.creatorGrozdanić, Nadja
dc.creatorKulišić, Zoran
dc.creatorJuranić, Zorica
dc.date.accessioned2020-06-03T13:47:20Z
dc.date.available2020-06-03T13:47:20Z
dc.date.issued2014
dc.identifier.issn0354-4664
dc.identifier.urihttps://vet-erinar.vet.bg.ac.rs/handle/123456789/1084
dc.description.abstractTanaceti partheni, Hypericum perforatum and propolis have been widely used for centuries and are well-documented medicinal plants and natural product. In this study, we investigated the antiproliferative effects of water extracts of ethanolic dry extracts of two different medicinal plants (Tanaceti partheni and Hypericum perforatum) and propolis on HeLa cells. The Tanaceti partheni extract exhibited mild cytotoxic activity The IC50 was 153.71 mu g/mL. The extract of Hypericum perforatum did not show active cytotoxic activity against HeLa cells (IC50 >200 [mu g/mL). Regarding the antiproliferative effects of Hypericum perforatum, our results are not in correlation with the results of other authors, probably because different Hypericum species and different human cancer cell lines were used. The extract of propolis did not show active cytotoxic activity against HeLa cells (IC50 +/- 1.08 0.01 mg/mL). The weak antiproliferative effect of propolis on HeLa cells is either due to the use of a low concentration of propolis extracted in weakly polar solvents, or the use of propolis collected in the autumn.en
dc.publisherSrpsko biološko društvo, Beograd
dc.relationMinistry of Education and Science of Republic of Serbia [34021]
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175011/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceArchives of Biological Sciences
dc.subjectAntiproliferative effecten
dc.subjectTanaceti parthenien
dc.subjectHypericum perforatumen
dc.subjectpropolisen
dc.titleAntiproliferative effects of tanaceti partheni, hypericum perforatum and propolis on hela cellsen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractКулишић, Зоран; Ценић-Милошевић, Десанка; Тамбур, Зоран; Јуранић, Зорица; Иванцајић, С.; Станојковић, Татјана; Грозданић, Надја;
dc.citation.volume66
dc.citation.issue2
dc.citation.spage705
dc.citation.epage712
dc.citation.other66(2): 705-712
dc.citation.rankM23
dc.identifier.wos000342265800029
dc.identifier.doi10.2298/ABS1402705M
dc.identifier.scopus2-s2.0-84903955416
dc.identifier.fulltexthttps://vet-erinar.vet.bg.ac.rs/bitstream/id/77/1083.pdf
dc.type.versionpublishedVersion


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