Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis
Само за регистроване кориснике
2014
Аутори
Matijatko, VesnaTorti, Mann
Kis, Ivana
Smit, Iva
Stoković, Igor
Vranješ-Đurić, Sanja
Milanović, Svetlana
Mrljak, Vladimir
Brkljacić, Mirna
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Babesiosis is an emerging tick-transmitted infectious disease of vertebrates that occurs worldwide. In Europe the predominant cause of canine babesiosis is Babesia canis. The disease can be clinically classified into uncomplicated and complicated forms. Both uncomplicated and complicated babesiosis due to Babesia canis appear to be the result of host inflammatory responses. The main aim of this study was to investigate the endocrine anti-inflammatory response in dogs naturally infected with Babesia canis. It was demonstrated that a marked endocrine response occurs in dogs naturally infected with Babesia canis, with significant increases in the concentration of cortisol and insulin. Statistically significant differences were found between the studied groups for all variables (cortisol, insulin and glucose) before the antibabesial treatment. The day after treatment a statistically significant difference was found between healthy dogs and the dogs that survived, as well as the dogs that d...ied, for cortisol and glucose, but not for insulin. In all of the studied dog groups the median value of glucose was within the reference range, but one animal within the group of dogs that survived was hypoglycemic before the antibabesial treatment. After the antibabesial treatment all the studied animals had glucose values within the reference range. A statistically significant positive correlation was found between cortisol and insulin. The results of this study showed that concentrations of cortisol and insulin can be used to predict mortality in canine babesiosis caused by B. canis.
Кључне речи:
endocrine response / compensatory anti-inflammatory response syndrome / dogs / babesiosis / insulin / cortisolИзвор:
Veterinarski Arhiv, 2014, 84, 6, 551-562Издавач:
- Univ Zagreb Vet Faculty, Zagreb
Финансирање / пројекти:
- Ministry of Science, Education and Sports of the Republic of CroatiaMinistry of Science, Education and Sports, Republic of Croatia [053-0532266-2220]
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Matijatko, Vesna AU - Torti, Mann AU - Kis, Ivana AU - Smit, Iva AU - Stoković, Igor AU - Vranješ-Đurić, Sanja AU - Milanović, Svetlana AU - Mrljak, Vladimir AU - Brkljacić, Mirna PY - 2014 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1094 AB - Babesiosis is an emerging tick-transmitted infectious disease of vertebrates that occurs worldwide. In Europe the predominant cause of canine babesiosis is Babesia canis. The disease can be clinically classified into uncomplicated and complicated forms. Both uncomplicated and complicated babesiosis due to Babesia canis appear to be the result of host inflammatory responses. The main aim of this study was to investigate the endocrine anti-inflammatory response in dogs naturally infected with Babesia canis. It was demonstrated that a marked endocrine response occurs in dogs naturally infected with Babesia canis, with significant increases in the concentration of cortisol and insulin. Statistically significant differences were found between the studied groups for all variables (cortisol, insulin and glucose) before the antibabesial treatment. The day after treatment a statistically significant difference was found between healthy dogs and the dogs that survived, as well as the dogs that died, for cortisol and glucose, but not for insulin. In all of the studied dog groups the median value of glucose was within the reference range, but one animal within the group of dogs that survived was hypoglycemic before the antibabesial treatment. After the antibabesial treatment all the studied animals had glucose values within the reference range. A statistically significant positive correlation was found between cortisol and insulin. The results of this study showed that concentrations of cortisol and insulin can be used to predict mortality in canine babesiosis caused by B. canis. PB - Univ Zagreb Vet Faculty, Zagreb T2 - Veterinarski Arhiv T1 - Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis VL - 84 IS - 6 SP - 551 EP - 562 UR - https://hdl.handle.net/21.15107/rcub_veterinar_1094 ER -
@article{ author = "Matijatko, Vesna and Torti, Mann and Kis, Ivana and Smit, Iva and Stoković, Igor and Vranješ-Đurić, Sanja and Milanović, Svetlana and Mrljak, Vladimir and Brkljacić, Mirna", year = "2014", abstract = "Babesiosis is an emerging tick-transmitted infectious disease of vertebrates that occurs worldwide. In Europe the predominant cause of canine babesiosis is Babesia canis. The disease can be clinically classified into uncomplicated and complicated forms. Both uncomplicated and complicated babesiosis due to Babesia canis appear to be the result of host inflammatory responses. The main aim of this study was to investigate the endocrine anti-inflammatory response in dogs naturally infected with Babesia canis. It was demonstrated that a marked endocrine response occurs in dogs naturally infected with Babesia canis, with significant increases in the concentration of cortisol and insulin. Statistically significant differences were found between the studied groups for all variables (cortisol, insulin and glucose) before the antibabesial treatment. The day after treatment a statistically significant difference was found between healthy dogs and the dogs that survived, as well as the dogs that died, for cortisol and glucose, but not for insulin. In all of the studied dog groups the median value of glucose was within the reference range, but one animal within the group of dogs that survived was hypoglycemic before the antibabesial treatment. After the antibabesial treatment all the studied animals had glucose values within the reference range. A statistically significant positive correlation was found between cortisol and insulin. The results of this study showed that concentrations of cortisol and insulin can be used to predict mortality in canine babesiosis caused by B. canis.", publisher = "Univ Zagreb Vet Faculty, Zagreb", journal = "Veterinarski Arhiv", title = "Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis", volume = "84", number = "6", pages = "551-562", url = "https://hdl.handle.net/21.15107/rcub_veterinar_1094" }
Matijatko, V., Torti, M., Kis, I., Smit, I., Stoković, I., Vranješ-Đurić, S., Milanović, S., Mrljak, V.,& Brkljacić, M.. (2014). Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis. in Veterinarski Arhiv Univ Zagreb Vet Faculty, Zagreb., 84(6), 551-562. https://hdl.handle.net/21.15107/rcub_veterinar_1094
Matijatko V, Torti M, Kis I, Smit I, Stoković I, Vranješ-Đurić S, Milanović S, Mrljak V, Brkljacić M. Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis. in Veterinarski Arhiv. 2014;84(6):551-562. https://hdl.handle.net/21.15107/rcub_veterinar_1094 .
Matijatko, Vesna, Torti, Mann, Kis, Ivana, Smit, Iva, Stoković, Igor, Vranješ-Đurić, Sanja, Milanović, Svetlana, Mrljak, Vladimir, Brkljacić, Mirna, "Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis" in Veterinarski Arhiv, 84, no. 6 (2014):551-562, https://hdl.handle.net/21.15107/rcub_veterinar_1094 .