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dc.creatorMatijatko, Vesna
dc.creatorTorti, Mann
dc.creatorKis, Ivana
dc.creatorSmit, Iva
dc.creatorStoković, Igor
dc.creatorVranješ-Đurić, Sanja
dc.creatorMilanović, Svetlana
dc.creatorMrljak, Vladimir
dc.creatorBrkljacić, Mirna
dc.date.accessioned2020-06-03T13:48:02Z
dc.date.available2020-06-03T13:48:02Z
dc.date.issued2014
dc.identifier.issn0372-5480
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/1094
dc.description.abstractBabesiosis is an emerging tick-transmitted infectious disease of vertebrates that occurs worldwide. In Europe the predominant cause of canine babesiosis is Babesia canis. The disease can be clinically classified into uncomplicated and complicated forms. Both uncomplicated and complicated babesiosis due to Babesia canis appear to be the result of host inflammatory responses. The main aim of this study was to investigate the endocrine anti-inflammatory response in dogs naturally infected with Babesia canis. It was demonstrated that a marked endocrine response occurs in dogs naturally infected with Babesia canis, with significant increases in the concentration of cortisol and insulin. Statistically significant differences were found between the studied groups for all variables (cortisol, insulin and glucose) before the antibabesial treatment. The day after treatment a statistically significant difference was found between healthy dogs and the dogs that survived, as well as the dogs that died, for cortisol and glucose, but not for insulin. In all of the studied dog groups the median value of glucose was within the reference range, but one animal within the group of dogs that survived was hypoglycemic before the antibabesial treatment. After the antibabesial treatment all the studied animals had glucose values within the reference range. A statistically significant positive correlation was found between cortisol and insulin. The results of this study showed that concentrations of cortisol and insulin can be used to predict mortality in canine babesiosis caused by B. canis.en
dc.publisherUniv Zagreb Vet Faculty, Zagreb
dc.relationMinistry of Science, Education and Sports of the Republic of CroatiaMinistry of Science, Education and Sports, Republic of Croatia [053-0532266-2220]
dc.rightsrestrictedAccess
dc.sourceVeterinarski Arhiv
dc.subjectendocrine responseen
dc.subjectcompensatory anti-inflammatory response syndromeen
dc.subjectdogsen
dc.subjectbabesiosisen
dc.subjectinsulinen
dc.subjectcortisolen
dc.titleSerum cortisol and insulin concentrations in dogs naturally infected with Babesia canisen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractТорти, Манн; Милановић, Светлана; Бркљацић, Мирна; Матијатко, Весна; Кис, Ивана; Врањеш-Ђурић, Сања; Стоковић, Игор; Мрљак, Владимир; Смит, Ива;
dc.citation.volume84
dc.citation.issue6
dc.citation.spage551
dc.citation.epage562
dc.citation.other84(6): 551-562
dc.citation.rankM23
dc.identifier.wos000347668500002
dc.identifier.rcubconv_2034
dc.type.versionpublishedVersion


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