Supplemental selenium reduces the levels of biomarkers of oxidative and general stress in peripartum dairy cows
2015
Autori
Jovanović, Ivan B.Velicković, Miljan
Milanović, Svetlana
Valčić, Olivera
Gvozdić, Dragan
Vranješ-Đurić, Sanja
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The aim of this investigation was to determine the influence of oxidative stress upon general stress in dairy cows on parturition and whether the indicators of stress can be reduced by selenium (Se) supplementation. A total of 36 animals were divided into 3 groups 21 days prepartum and treated with a single-term intra muscular supplement of sodium selenite: Control group - 0 mg; group Se10 - 10 mg; group Se20 - 20 mg. Se supplementation significantly raised blood Se content and glutathione peroxidase (GPx) activity in groups Se10 and Se20, compared to Control, although there was no marked difference between supplemented groups. Plasma malondialdehyde (MDA) and cortisol concentrations were significantly reduced in supplemented groups Se10 and Se20, compared to Control. A negative correlation was detected between blood GPx activity and plasma MDA, while a positive correlation was determined between plasma MDA and cortisol concentrations. These results indicate that prepartum Se supplemen...tation can be utilized for a partial relief of stress in cows during labor by augmenting the antioxidative action of GPx.
Ključne reči:
Selenium / dairy cows / peripartum period / MDA / cortisol / stressIzvor:
Acta Veterinaria-Beograd, 2015, 65, 2, 191-201Izdavač:
- Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
Finansiranje / projekti:
- Biotehnologija u regulaciji proizvodnog i reproduktivnog statusa i zdravstvenog stanja kod visoko-mlečnih krava (RS-MESTD-Technological Development (TD or TR)-31050)
- Razvoj tehnologija i proizvoda na bazi mineralnih sirovina i otpadne biomase u cilju zaštite resursa za proizvodnju bezbedne hrane (RS-MESTD-Technological Development (TD or TR)-31003)
DOI: 10.1515/acve-2015-0016
ISSN: 0567-8315
WoS: 000356832100004
Scopus: 2-s2.0-84933531510
Kolekcije
Institucija/grupa
Fakultet veterinarske medicineTY - JOUR AU - Jovanović, Ivan B. AU - Velicković, Miljan AU - Milanović, Svetlana AU - Valčić, Olivera AU - Gvozdić, Dragan AU - Vranješ-Đurić, Sanja PY - 2015 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1182 AB - The aim of this investigation was to determine the influence of oxidative stress upon general stress in dairy cows on parturition and whether the indicators of stress can be reduced by selenium (Se) supplementation. A total of 36 animals were divided into 3 groups 21 days prepartum and treated with a single-term intra muscular supplement of sodium selenite: Control group - 0 mg; group Se10 - 10 mg; group Se20 - 20 mg. Se supplementation significantly raised blood Se content and glutathione peroxidase (GPx) activity in groups Se10 and Se20, compared to Control, although there was no marked difference between supplemented groups. Plasma malondialdehyde (MDA) and cortisol concentrations were significantly reduced in supplemented groups Se10 and Se20, compared to Control. A negative correlation was detected between blood GPx activity and plasma MDA, while a positive correlation was determined between plasma MDA and cortisol concentrations. These results indicate that prepartum Se supplementation can be utilized for a partial relief of stress in cows during labor by augmenting the antioxidative action of GPx. PB - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd T2 - Acta Veterinaria-Beograd T1 - Supplemental selenium reduces the levels of biomarkers of oxidative and general stress in peripartum dairy cows VL - 65 IS - 2 SP - 191 EP - 201 DO - 10.1515/acve-2015-0016 ER -
@article{ author = "Jovanović, Ivan B. and Velicković, Miljan and Milanović, Svetlana and Valčić, Olivera and Gvozdić, Dragan and Vranješ-Đurić, Sanja", year = "2015", abstract = "The aim of this investigation was to determine the influence of oxidative stress upon general stress in dairy cows on parturition and whether the indicators of stress can be reduced by selenium (Se) supplementation. A total of 36 animals were divided into 3 groups 21 days prepartum and treated with a single-term intra muscular supplement of sodium selenite: Control group - 0 mg; group Se10 - 10 mg; group Se20 - 20 mg. Se supplementation significantly raised blood Se content and glutathione peroxidase (GPx) activity in groups Se10 and Se20, compared to Control, although there was no marked difference between supplemented groups. Plasma malondialdehyde (MDA) and cortisol concentrations were significantly reduced in supplemented groups Se10 and Se20, compared to Control. A negative correlation was detected between blood GPx activity and plasma MDA, while a positive correlation was determined between plasma MDA and cortisol concentrations. These results indicate that prepartum Se supplementation can be utilized for a partial relief of stress in cows during labor by augmenting the antioxidative action of GPx.", publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd", journal = "Acta Veterinaria-Beograd", title = "Supplemental selenium reduces the levels of biomarkers of oxidative and general stress in peripartum dairy cows", volume = "65", number = "2", pages = "191-201", doi = "10.1515/acve-2015-0016" }
Jovanović, I. B., Velicković, M., Milanović, S., Valčić, O., Gvozdić, D.,& Vranješ-Đurić, S.. (2015). Supplemental selenium reduces the levels of biomarkers of oxidative and general stress in peripartum dairy cows. in Acta Veterinaria-Beograd Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 65(2), 191-201. https://doi.org/10.1515/acve-2015-0016
Jovanović IB, Velicković M, Milanović S, Valčić O, Gvozdić D, Vranješ-Đurić S. Supplemental selenium reduces the levels of biomarkers of oxidative and general stress in peripartum dairy cows. in Acta Veterinaria-Beograd. 2015;65(2):191-201. doi:10.1515/acve-2015-0016 .
Jovanović, Ivan B., Velicković, Miljan, Milanović, Svetlana, Valčić, Olivera, Gvozdić, Dragan, Vranješ-Đurić, Sanja, "Supplemental selenium reduces the levels of biomarkers of oxidative and general stress in peripartum dairy cows" in Acta Veterinaria-Beograd, 65, no. 2 (2015):191-201, https://doi.org/10.1515/acve-2015-0016 . .