Characterization of tetracycline resistance of salmonella enterica subspecies enterica serovar infantis isolated from poultry in the northern part of Serbia
2015
Autori
Todorović, DaliborVelhner, Maja
Milanov, Dubravka
Vidanović, Dejan
Suvajdzić, Ljiljana
Stojanov, Igor
Krnjaić, Dejan
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Resistance to tetracycline was studied in Salmonella Infantis isolated from 28 poultry farms in the Northern part of Serbia (The Autonomous Province of Vojvodina). A total of 18 isolates were resistant to nalidixic acid (NAL) and tetracycline (TET). The minimal inhibitory concentration (MIC) to TET, ranged from 1-256 mg/L. Namely, 13 isolates exhibited MIC to TET at 256 mg/L, in four of the isolates, the MIC was 128 mg/L and one isolate had MIC 64 mg/L. Ten isolates were exhibiting a MIC of 1mg/L. It was evident that Salmonella Infantis had also spread to breeders and layers. In this work, we detected the tetA gene and the corresponding tetR gene (encoding the repressor protein) as well as the truncated transposon Tn1721, which are responsible for the resistance to TET. The presence of the non conjugative transposons from the conjugative plasmid has facilitated the spread of resistance to TET in Salmonella. It was concluded that higher biosecurity practice in poultry farming presents t...he best option to eliminate infections caused by Salmonella spp. from poultry flocks in Serbia. A rational use of antimicrobials is necessary to prevent any further spread of Salmonella Infantis resistant clones.
Izvor:
Acta Veterinaria-Beograd, 2015, 65, 4, 548-556Izdavač:
- Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
Finansiranje / projekti:
DOI: 10.1515/acve-2015-0046
ISSN: 0567-8315
WoS: 000367467000010
Scopus: 2-s2.0-84955451917
Kolekcije
Institucija/grupa
Fakultet veterinarske medicineTY - JOUR AU - Todorović, Dalibor AU - Velhner, Maja AU - Milanov, Dubravka AU - Vidanović, Dejan AU - Suvajdzić, Ljiljana AU - Stojanov, Igor AU - Krnjaić, Dejan PY - 2015 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1191 AB - Resistance to tetracycline was studied in Salmonella Infantis isolated from 28 poultry farms in the Northern part of Serbia (The Autonomous Province of Vojvodina). A total of 18 isolates were resistant to nalidixic acid (NAL) and tetracycline (TET). The minimal inhibitory concentration (MIC) to TET, ranged from 1-256 mg/L. Namely, 13 isolates exhibited MIC to TET at 256 mg/L, in four of the isolates, the MIC was 128 mg/L and one isolate had MIC 64 mg/L. Ten isolates were exhibiting a MIC of 1mg/L. It was evident that Salmonella Infantis had also spread to breeders and layers. In this work, we detected the tetA gene and the corresponding tetR gene (encoding the repressor protein) as well as the truncated transposon Tn1721, which are responsible for the resistance to TET. The presence of the non conjugative transposons from the conjugative plasmid has facilitated the spread of resistance to TET in Salmonella. It was concluded that higher biosecurity practice in poultry farming presents the best option to eliminate infections caused by Salmonella spp. from poultry flocks in Serbia. A rational use of antimicrobials is necessary to prevent any further spread of Salmonella Infantis resistant clones. PB - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd T2 - Acta Veterinaria-Beograd T1 - Characterization of tetracycline resistance of salmonella enterica subspecies enterica serovar infantis isolated from poultry in the northern part of Serbia VL - 65 IS - 4 SP - 548 EP - 556 DO - 10.1515/acve-2015-0046 ER -
@article{ author = "Todorović, Dalibor and Velhner, Maja and Milanov, Dubravka and Vidanović, Dejan and Suvajdzić, Ljiljana and Stojanov, Igor and Krnjaić, Dejan", year = "2015", abstract = "Resistance to tetracycline was studied in Salmonella Infantis isolated from 28 poultry farms in the Northern part of Serbia (The Autonomous Province of Vojvodina). A total of 18 isolates were resistant to nalidixic acid (NAL) and tetracycline (TET). The minimal inhibitory concentration (MIC) to TET, ranged from 1-256 mg/L. Namely, 13 isolates exhibited MIC to TET at 256 mg/L, in four of the isolates, the MIC was 128 mg/L and one isolate had MIC 64 mg/L. Ten isolates were exhibiting a MIC of 1mg/L. It was evident that Salmonella Infantis had also spread to breeders and layers. In this work, we detected the tetA gene and the corresponding tetR gene (encoding the repressor protein) as well as the truncated transposon Tn1721, which are responsible for the resistance to TET. The presence of the non conjugative transposons from the conjugative plasmid has facilitated the spread of resistance to TET in Salmonella. It was concluded that higher biosecurity practice in poultry farming presents the best option to eliminate infections caused by Salmonella spp. from poultry flocks in Serbia. A rational use of antimicrobials is necessary to prevent any further spread of Salmonella Infantis resistant clones.", publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd", journal = "Acta Veterinaria-Beograd", title = "Characterization of tetracycline resistance of salmonella enterica subspecies enterica serovar infantis isolated from poultry in the northern part of Serbia", volume = "65", number = "4", pages = "548-556", doi = "10.1515/acve-2015-0046" }
Todorović, D., Velhner, M., Milanov, D., Vidanović, D., Suvajdzić, L., Stojanov, I.,& Krnjaić, D.. (2015). Characterization of tetracycline resistance of salmonella enterica subspecies enterica serovar infantis isolated from poultry in the northern part of Serbia. in Acta Veterinaria-Beograd Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 65(4), 548-556. https://doi.org/10.1515/acve-2015-0046
Todorović D, Velhner M, Milanov D, Vidanović D, Suvajdzić L, Stojanov I, Krnjaić D. Characterization of tetracycline resistance of salmonella enterica subspecies enterica serovar infantis isolated from poultry in the northern part of Serbia. in Acta Veterinaria-Beograd. 2015;65(4):548-556. doi:10.1515/acve-2015-0046 .
Todorović, Dalibor, Velhner, Maja, Milanov, Dubravka, Vidanović, Dejan, Suvajdzić, Ljiljana, Stojanov, Igor, Krnjaić, Dejan, "Characterization of tetracycline resistance of salmonella enterica subspecies enterica serovar infantis isolated from poultry in the northern part of Serbia" in Acta Veterinaria-Beograd, 65, no. 4 (2015):548-556, https://doi.org/10.1515/acve-2015-0046 . .