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dc.creatorPopović, M.
dc.creatorKaurinović, B
dc.creatorMimica-Dukić, Neda
dc.creatorVojinović-Miloradov, Mirjana
dc.creatorĆupić, Vitomir
dc.date.accessioned2020-06-03T12:39:46Z
dc.date.available2020-06-03T12:39:46Z
dc.date.issued1999
dc.identifier.issn0209-4541
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/120
dc.description.abstractMethanolic (70%) extracts of marigold flower, leaf, stem and root, after solvent removal, were successively extracted with ether, chloroform, ethyl acetate, and n-butanol - the residue being the corresponding aqueous extract. All five extracts were evaporated to dryness and then dissolved in 50% EtOH to obtain 6% (w/v) solutions. These solutions, either alone or in combination with different doses of ciprofloxacin or pyralene, were used to study their effect on liposomal lipid peroxidation (LPx) induced by Fe 2+ and ascorbic acid. The majority of the extracts of marigold flower, leaf and stem showed an antioxidant effect, the butanol extract of roots exhibiting a pro-oxidative character. At lower doses, ciprofloxacin did not affect LPx, at higher doses a dose-dependent increase in LPx was observed. The extracts in combination with ciprofloxacin showed a protective effect, which was also dose-dependent. The butanolic extract of root snowed no synergistic effect with ciprofloxacin. Pyralene alone exhibited a pro-oxidative action on liposomal LPx. Aqueous and butanolic extracts of flower, leaf, and stem had a protective effect in combination with pyralene. The butanolic extract of root showed a pro-oxidative synergistic effect with pyralene.en
dc.publisherScibulcom Ltd, Sofia
dc.rightsrestrictedAccess
dc.sourceOxidation Communications
dc.subjectmarigolden
dc.subjectpolychlorinated biphenylsen
dc.subjectliposomesen
dc.subjectlipid peroxidationen
dc.titleCombined effects of plant extracts and xenobiotics on liposomal lipid peroxidation. Part 1. Marigold extract-ciprofloxacin/pyraleneen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЋупић, Витомир; Поповић, М.; Кауриновић, Б; Мимица-Дукић, Неда; Војиновић-Милорадов, Мирјана;
dc.citation.volume22
dc.citation.issue4
dc.citation.spage487
dc.citation.epage494
dc.citation.other22(4): 487-494
dc.citation.rankM23
dc.identifier.wos000084540600002
dc.identifier.scopus2-s2.0-0033236872
dc.identifier.rcubconv_1321
dc.type.versionpublishedVersion


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