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Combined effects of plant extracts and xenobiotics on liposomal lipid peroxidation. Part 1. Marigold extract-ciprofloxacin/pyralene
dc.creator | Popović, M. | |
dc.creator | Kaurinović, B | |
dc.creator | Mimica-Dukić, Neda | |
dc.creator | Vojinović-Miloradov, Mirjana | |
dc.creator | Ćupić, Vitomir | |
dc.date.accessioned | 2020-06-03T12:39:46Z | |
dc.date.available | 2020-06-03T12:39:46Z | |
dc.date.issued | 1999 | |
dc.identifier.issn | 0209-4541 | |
dc.identifier.uri | https://vet-erinar.vet.bg.ac.rs/handle/123456789/120 | |
dc.description.abstract | Methanolic (70%) extracts of marigold flower, leaf, stem and root, after solvent removal, were successively extracted with ether, chloroform, ethyl acetate, and n-butanol - the residue being the corresponding aqueous extract. All five extracts were evaporated to dryness and then dissolved in 50% EtOH to obtain 6% (w/v) solutions. These solutions, either alone or in combination with different doses of ciprofloxacin or pyralene, were used to study their effect on liposomal lipid peroxidation (LPx) induced by Fe 2+ and ascorbic acid. The majority of the extracts of marigold flower, leaf and stem showed an antioxidant effect, the butanol extract of roots exhibiting a pro-oxidative character. At lower doses, ciprofloxacin did not affect LPx, at higher doses a dose-dependent increase in LPx was observed. The extracts in combination with ciprofloxacin showed a protective effect, which was also dose-dependent. The butanolic extract of root snowed no synergistic effect with ciprofloxacin. Pyralene alone exhibited a pro-oxidative action on liposomal LPx. Aqueous and butanolic extracts of flower, leaf, and stem had a protective effect in combination with pyralene. The butanolic extract of root showed a pro-oxidative synergistic effect with pyralene. | en |
dc.publisher | Scibulcom Ltd, Sofia | |
dc.rights | restrictedAccess | |
dc.source | Oxidation Communications | |
dc.subject | marigold | en |
dc.subject | polychlorinated biphenyls | en |
dc.subject | liposomes | en |
dc.subject | lipid peroxidation | en |
dc.title | Combined effects of plant extracts and xenobiotics on liposomal lipid peroxidation. Part 1. Marigold extract-ciprofloxacin/pyralene | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Ћупић, Витомир; Поповић, М.; Кауриновић, Б; Мимица-Дукић, Неда; Војиновић-Милорадов, Мирјана; | |
dc.citation.volume | 22 | |
dc.citation.issue | 4 | |
dc.citation.spage | 487 | |
dc.citation.epage | 494 | |
dc.citation.other | 22(4): 487-494 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000084540600002 | |
dc.identifier.scopus | 2-s2.0-0033236872 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_veterinar_120 | |
dc.type.version | publishedVersion |
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