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Histološki efekti gleđnih proteina na eksponiranu pulpu zuba

dc.creatorPopović-Bajić, Marijana
dc.creatorDanilović, Vesna
dc.creatorProkić, Branislav
dc.creatorProkić, Bogomir Bolka
dc.creatorManojlović, Milica
dc.creatorŽivković, Slavoljub
dc.date.accessioned2020-06-03T13:56:22Z
dc.date.available2020-06-03T13:56:22Z
dc.date.issued2015
dc.identifier.issn0370-8179
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/1215
dc.description.abstractIntroduction Direct pulp capping procedure is a therapeutic application of a drug on exposed tooth pulp in order to ensure the closure of the pulp chamber and to allow the healing process to take place. Objective The aim of this study was to examine the histological effects of Emdogain® on exposed tooth pulp of a Vietnamese pig (Sus scrofa verus). Methods The study comprised 20 teeth of a Vietnamese pig. After class V preparation on the buccal surfaces of incisors, canines and first premolars, pulp was exposed. In the experimental group, the perforations were capped with Emdogain® (Straumann, Basel, Switzerland), while in the control group pulp capping was performed with MTA® (Dentsply Tulsa Dental, Johnson City, TN, USA). All cavities were restored with glass-ionomer cement (GC Fuji VIII, GC Corporation, Tokyo, Japan). The observational period was 28 days, after which the animal was sacrificed and histological preparations were made. A light microscope was used to analyze dentin bridge formation, tissue reorganization and inflammation, and the presence of bacteria in the pulp. Results The formation of dentin bridge was observed in the experimental and control groups. Inflammation of the pulp was mild to moderate in both groups. Angiogenesis and many odontoblast-like cells, responsible for dentin bridge formation, were observed. Necrosis was not observed in any case, nor were bacteria present in the pulp. Conclusion Histological analysis indicated a favorable therapeutic effect of Emdogain® Gel in direct pulp capping of Vietnamese pigs. Pulp reaction was similar to that of MTA®.en
dc.description.abstractUvod Direktno prekrivanje pulpe je važan terapijski postupak primene leka na eksponiranu pulpu zuba, čiji je cilj da obezbedi zatvaranje pulpne komore i omogući proces zarastanja. Cilj rada Cilj ovog rada je bio da se histološki ispita efekat gleđnog emdogaina na eksponiranu pulpu zuba vijetnamske svinje (Sus scrofa domesticus). Metode rada Istraživanje je urađeno na 20 zuba vijetnamske svinje. Na vestibularnim površinama sekutića, očnjaka i prvih premolara urađene su preparacije kaviteta V klase s eksponiranjem komora pulpe. U eksperimentalnoj grupi perforacija je prekrivana proizvodom Emdogain® (Straumann, Bazel, Švajcarska), a u kontrolnoj sa MTA® (Dentsply Tulsa Dental, Džonson Siti, Tenesi, SAD). Svi kaviteti su restaurirani glasjonomer-cementom (GC Fuji VIII, GC Corporation, Tokio, Japan). Period posmatranja trajao je 28 dana, a nakon žrtvovanja životinja, napravljeni su histološki preparati na kojima su analizirani postojanje dentinskog mostića, zapaljenjska reakcija pulpe, reorganizacija pulpnog tkiva i postojanje bakterija. Rezultati Na svim zubima eksperimentalne i kontrolne grupe uočeno je stvaranje dentinskog mostića. Upala pulpe je bila blaga do umerena i u eksperimentalnoj i u kontrolnoj grupi. Uočeni su znaci neoangiogeneze i mnoštvo ćelija sličnih odontoblastima koje su odgovorne za stvaranje dentinskog mostića. Nekroza nije zabeležena ni u jednom slučaju, kao ni prisustvo bakterija u pulpi. Zaključak Histološka analiza je ukazala na povoljne terapijske efekte emdogaina u direktnom prekrivanju pulpe zuba vijetnamskih svinja. Reakcija pulpe bila je slična onima koje je izazvao MTA.sr
dc.publisherSrpsko lekarsko društvo, Beograd
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172026/RS//
dc.rightsopenAccess
dc.sourceSrpski arhiv za celokupno lekarstvo
dc.subjectdirect pulp cappingen
dc.subjectenamel proteinen
dc.subjectVietnamese pigen
dc.subjectdirektno prekrivanje pulpesr
dc.subjectgleđni proteinisr
dc.subjectvijetnamske svinjesr
dc.titleHistological effects of enamel matrix derivative on exposed dental pulpen
dc.titleHistološki efekti gleđnih proteina na eksponiranu pulpu zubasr
dc.typearticle
dc.rights.licenseBY-NC
dcterms.abstractПрокић, Бранислав; Живковић, Славољуб; Прокић, Богомир Болка; Поповић-Бајић, Маријана; Манојловић, Милица; Даниловић, Весна; Хистолошки ефекти глеђних протеина на експонирану пулпу зуба; Хистолошки ефекти глеђних протеина на експонирану пулпу зуба;
dc.citation.volume143
dc.citation.issue7-8
dc.citation.spage397
dc.citation.epage403
dc.citation.other143(7-8): 397-403
dc.citation.rankM23
dc.identifier.wos000361332200003
dc.identifier.doi10.2298/SARH1508397P
dc.identifier.scopus2-s2.0-84941203406
dc.identifier.fulltexthttp://veterinar.vet.bg.ac.rs/bitstream/id/194/1214.pdf
dc.identifier.rcubconv_442
dc.type.versionpublishedVersion


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