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dc.creatorDebeljak, Zoran
dc.creatorBoufana, Belgees
dc.creatorInterisano, Maria
dc.creatorVidanović, Dejan
dc.creatorKulišić, Zoran
dc.creatorCasulli, Adriano
dc.date.accessioned2020-06-03T14:09:42Z
dc.date.available2020-06-03T14:09:42Z
dc.date.issued2016
dc.identifier.issn0304-4017
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/1404
dc.description.abstractCystic echinococcosis (CE) caused by Echinococcus granulosus sensu stricto (s.s.) is a cosmopolitan zoonotic infection which is endemic in Serbia where it is subject to mandatory reporting. However, information on the incidence of the disease in humans and prevalence of hydatid infection in livestock remains limited. We used sequenced data of the cytochrome c oxidase subunit 1 (cox 1) mitochondrial gene to examine the genetic diversity and population structure of E. granulosus (s.s.) from intermediate hosts from Serbia. We also compared our generated nucleotide sequences with those reported for neighbouring European countries. Echinococcus canadensis was molecularly confirmed from pig and human hydatid isolates. E. granulosus (G1) was confirmed from sheep and cattle hydatid isolates as well as the first molecular confirmation in Serbia of E. granulosus G2 in sheep and E. granulosus G3 in sheep and cattle hydatid isolates. The Serbian E. granulosus (s.s.) parsimony network displayed 2 main haplotypes (SB02 and SB05) which together with the neutrality indices were suggestive of bottleneck and/or balancing selection. Haplotype analysis showed the presence of the common E. granulosus haplotype described from other worldwide regions. Investigation of the pairwise fixation (Fst) index suggested that Serbian populations of E. granulosus (s.s.) from sheep and cattle hosts showed moderate genetic differentiation. Six of the Serbian haplotypes (SB02-SB07) were shared with haplotypes from Bulgaria, Hungary and/or Romania. Further studies using a larger number of hydatid isolates from various locations across Serbia will provide more information on the genetic structure of E. granulosus (s.s.) within this region.en
dc.publisherElsevier Science Bv, Amsterdam
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/602051/EU//
dc.rightsrestrictedAccess
dc.sourceVeterinary Parasitology
dc.subjectEchinococcus granulosus sensu strictoen
dc.subjectGenetic diversityen
dc.subjectSerbiaen
dc.titleFirst insights into the genetic diversity of Echinococcus granulosus sensu stricto (s.s.) in Serbiaen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractКулишић, Зоран; Дебељак, Зоран; Цасулли, Aдриано; Видановић, Дејан; Интерисано, Мариа; Боуфана, Белгеес;
dc.citation.volume223
dc.citation.spage57
dc.citation.epage62
dc.citation.other223: 57-62
dc.citation.rankaM21
dc.identifier.wos000377317200011
dc.identifier.doi10.1016/j.vetpar.2016.04.007
dc.identifier.pmid27198778
dc.identifier.scopus2-s2.0-84963894030
dc.identifier.rcubconv_2155
dc.type.versionpublishedVersion


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