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dc.creatorMilovanović, Stoja
dc.creatorMarković, Darka
dc.creatorAksentijević, Ksenija
dc.creatorStojanović, Dusica B.
dc.creatorIvanović, Jasna
dc.creatorŽižović, Irena
dc.date.accessioned2020-06-03T14:09:46Z
dc.date.available2020-06-03T14:09:46Z
dc.date.issued2016
dc.identifier.issn0144-8617
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/1405
dc.description.abstractCellulose acetate (CA) was investigated as a carrier towards development of material with controlled release of thymol as a natural substance with strong antibacterial properties using high pressure techniques. Effect of thymol content on CA was confirmed by SEM, FTIR and DSC methods. Kinetic of thymol release from CA was tested using simulated gastric and intestinal fluids (hydrochloric acid and phosphate buffer saline). Results were correlated with Korsmeyer-Peppas and Weibull model. Depending on the thymol content and chemical nature of the release medium, the time of thymol release varied from one to three days indicating CA as a promising carrier of thymol with potential uses from medicine to agriculture. The impregnated CA showed antibacterial activity against 23 tested bacterial strains including methicillin-resistant Staphylococcus aureus (MRSA) which is particularly important bearing in mind that this strain causes fatal infections in humans and animals.en
dc.publisherElsevier Sci Ltd, Oxford
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45017/RS//
dc.rightsrestrictedAccess
dc.sourceCarbohydrate Polymers
dc.subjectCellulose acetateen
dc.subjectThymolen
dc.subjectSupercritical impregnationen
dc.subjectControlled releaseen
dc.subjectAntibacterial activityen
dc.titleApplication of cellulose acetate for controlled release of thymolen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractИвановић, Јасна; Жижовић, Ирена; Aксентијевић, Ксенија; Марковић, Дарка; Стојановић, Дусица Б.; Миловановић, Стоја;
dc.citation.volume147
dc.citation.spage344
dc.citation.epage353
dc.citation.other147: 344-353
dc.citation.rankaM21
dc.identifier.wos000376449300040
dc.identifier.doi10.1016/j.carbpol.2016.03.093
dc.identifier.pmid27178940
dc.identifier.scopus2-s2.0-84964727138
dc.identifier.rcubconv_2153
dc.type.versionpublishedVersion


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