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dc.creatorDacić, Stefan
dc.creatorĐelić, Ninoslav
dc.creatorRadaković, Milena
dc.creatorLakić, Nada
dc.creatorVeselinović, Aleksandar
dc.creatorRistanić, Marko
dc.creatorAnđelković, Marko
dc.date.accessioned2020-06-03T14:09:59Z
dc.date.available2020-06-03T14:09:59Z
dc.date.issued2016
dc.identifier.issn0534-0012
dc.identifier.urihttps://vet-erinar.vet.bg.ac.rs/handle/123456789/1408
dc.description.abstractCertain in vivo studies have shown that the application of adhesives directly onto the open pulp or on a thin layer of dentin causes inflammation and pulpal abscesses. This reaction is related to toxic effects of monomers from adhesives. It has been confirmed that after proper illumination the adhesives become less toxic. The aim of the study was to examine genotoxicity of non-polymerised, partly polymerised and polymerised adhesives on isolated human lymphocytes using the alkaline Comet assay. Adper Single bond2 and Adper Easy One/3M ESPE adhesive photopolymerisation was performed by Elipar Highlight 3M ESPE halogen lamp for 0, 10 and 40 sec, at final concentrations of 100, 200, 500 and 1000 mu g/mL. With both adhesives, photopolymerisation at 0 and 10 seconds showed statistically significant increase in DNA damage in comparision to the negative control (solvent). On the other hand, after 40 seconds of photopolymerisation of both adhesives in all tested concentrations, the degree of DNA damage in Comet assay had no significant difference (P>0.05, chi(2) test) compared to the negative control. Therefore, only the 40 seconds of photopolymerisation prevented genotoxic effects of both adhesives in the Comet assay.en
dc.publisherDruštvo genetičara Srbije, Beograd
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46002/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173012/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceGenetika
dc.subjectcomposite adhesivesen
dc.subjectphotopolymerisationen
dc.subjectgenotoxicityen
dc.subjectComet asssayen
dc.titleEffects of photopolymerisation on genotoxicity of composite adhesives in the comet assayen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractДацић, Стефан; Радаковић, Милена; Ристанић, Марко; Веселиновић, Aлександар; Ђелић, Нинослав; Aнђелковић, Марко; Лакић, Нада;
dc.citation.volume48
dc.citation.issue2
dc.citation.spage617
dc.citation.epage627
dc.citation.other48(2): 617-627
dc.citation.rankM23
dc.identifier.wos000389658100015
dc.identifier.doi10.2298/GENSR1602617D
dc.identifier.scopus2-s2.0-84994493576
dc.identifier.fulltexthttps://vet-erinar.vet.bg.ac.rs/bitstream/id/375/1407.pdf
dc.type.versionpublishedVersion


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