Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes
2017
Преузимање 🢃
Аутори
Mitrović, Marko JumakeCiraj-Bjelac, Olivera F.
Orescanin-Dusić, Zorana S.
Blagojević, Duško P.
Nikolic-Kokić, Aleksandra L.
Tatalović, Nikola R.
Krstić, Nikola
Lazarević Macanović, Mirjana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.
Кључне речи:
computed tomography / CT dose index / erythrocyte / antioxidant enzyme / rabbitИзвор:
Nuclear Technology and Radiation Protection, 2017, 32, 4, 342-349Издавач:
- Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd
Финансирање / пројекти:
- Молекуларни механизми редокс сигналинга у хомеостази, адаптацији и патологији (RS-MESTD-Basic Research (BR or ON)-173014)
DOI: 10.2298/NTRP1704342M
ISSN: 1451-3994
WoS: 000423779500005
Scopus: 2-s2.0-85041126436
Колекције
Институција/група
Fakultet veterinarske medicineTY - JOUR AU - Mitrović, Marko Jumake AU - Ciraj-Bjelac, Olivera F. AU - Orescanin-Dusić, Zorana S. AU - Blagojević, Duško P. AU - Nikolic-Kokić, Aleksandra L. AU - Tatalović, Nikola R. AU - Krstić, Nikola AU - Lazarević Macanović, Mirjana PY - 2017 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1447 AB - The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period. PB - Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd T2 - Nuclear Technology and Radiation Protection T1 - Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes VL - 32 IS - 4 SP - 342 EP - 349 DO - 10.2298/NTRP1704342M ER -
@article{ author = "Mitrović, Marko Jumake and Ciraj-Bjelac, Olivera F. and Orescanin-Dusić, Zorana S. and Blagojević, Duško P. and Nikolic-Kokić, Aleksandra L. and Tatalović, Nikola R. and Krstić, Nikola and Lazarević Macanović, Mirjana", year = "2017", abstract = "The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.", publisher = "Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd", journal = "Nuclear Technology and Radiation Protection", title = "Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes", volume = "32", number = "4", pages = "342-349", doi = "10.2298/NTRP1704342M" }
Mitrović, M. J., Ciraj-Bjelac, O. F., Orescanin-Dusić, Z. S., Blagojević, D. P., Nikolic-Kokić, A. L., Tatalović, N. R., Krstić, N.,& Lazarević Macanović, M.. (2017). Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes. in Nuclear Technology and Radiation Protection Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd., 32(4), 342-349. https://doi.org/10.2298/NTRP1704342M
Mitrović MJ, Ciraj-Bjelac OF, Orescanin-Dusić ZS, Blagojević DP, Nikolic-Kokić AL, Tatalović NR, Krstić N, Lazarević Macanović M. Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes. in Nuclear Technology and Radiation Protection. 2017;32(4):342-349. doi:10.2298/NTRP1704342M .
Mitrović, Marko Jumake, Ciraj-Bjelac, Olivera F., Orescanin-Dusić, Zorana S., Blagojević, Duško P., Nikolic-Kokić, Aleksandra L., Tatalović, Nikola R., Krstić, Nikola, Lazarević Macanović, Mirjana, "Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes" in Nuclear Technology and Radiation Protection, 32, no. 4 (2017):342-349, https://doi.org/10.2298/NTRP1704342M . .