Show simple item record

dc.creatorĐoković, Radojica
dc.creatorDosković, Vladimir
dc.creatorCincović, Marko
dc.creatorBelić, Branislava
dc.creatorFratrić, Natalija
dc.creatorJasović, Boban
dc.creatorLalović, Miroslav
dc.date.accessioned2020-06-03T14:19:50Z
dc.date.available2020-06-03T14:19:50Z
dc.date.issued2017
dc.identifier.issn0253-8318
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/1547
dc.description.abstractThe objective of this study was to determine insulin resistance in healthy (n=8) and ketotic (n=7) dairy cows based on the difference between basal and dynamic changes in glucose, insulin, non-esterified fatty acids (NEFA), ß-hydroxybutyrate (BHB) concentrations, and on the determination of their mutual relationship and relationship with insulin resistance indices (RQUICKI and RQUICKI-BHB), after intravenous glucose tolerance test (IVGTT). The RQUICKI index showed a significant linear correlation (P lt 0.05) with basal insulin, glucose, NEFA and BHB levels. However, RQUICKI-BHB index values exhibited a negative correlation (P lt 0.01) with basal NEFA and BHB values and their clearance rates, as well as with glucose clearance rate, and a positive correlation (P lt 0.05) with basal insulin values as well as with insulin and glucose responses during IVGTT. The correlation between basal values of these parameters and the values measured or calculated during IVGTT is the result of RQUICKI-BHB values, as the exclusion of RQUICKI-BHB leads to loss of the statistical significance of the correlations between basal and dynamic values. Insulin resistance in ketotic cows is characterized by decreased insulin response to glucose and increased insulin resistance of the tissue, their correlation being the result of the RQUICKI-BHB index value.en
dc.publisherUniv Agriculture, Fac Veterinary Science, Faisalabad
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31001/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31062/RS//
dc.rightsopenAccess
dc.sourcePakistan Veterinary Journal
dc.subjectCowsen
dc.subjectGlucose tolerance testen
dc.subjectInsulin resistanceen
dc.subjectKetosisen
dc.titleEstimation of insulin resistance in healthy and ketotic cows during an intravenous glucose tolerance testen
dc.typearticle
dc.rights.licensePublisher's own license
dc.rights.licenseARR
dcterms.abstractДосковић, Владимир; Лаловић, Мирослав; Јасовић, Бобан; Фратрић, Наталија; Белић, Бранислава; Цинцовић, Марко; Ђоковић, Радојица;
dc.citation.volume37
dc.citation.issue4
dc.citation.spage387
dc.citation.epage392
dc.citation.other37(4): 387-392
dc.citation.rankM22
dc.identifier.wos000417969000003
dc.identifier.scopus2-s2.0-85036608542
dc.identifier.rcubconv_2303
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record