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dc.creatorPetrujkić, Branko
dc.creatorBeier, Ross C.
dc.creatorHe, Haiqi
dc.creatorGenovese, Kenneth J.
dc.creatorSwaggerty, Christina L.
dc.creatorHume, Michael E.
dc.creatorCrippen, Tawni L.
dc.creatorHarvey, Roger B.
dc.creatorAnderson, Robin C.
dc.creatorNisbet, David J.
dc.date.accessioned2020-06-03T14:25:28Z
dc.date.available2020-06-03T14:25:28Z
dc.date.issued2018
dc.identifier.issn0022-5142
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/1627
dc.description.abstractBACKGROUNDNigella sativa L. (NS) is a plant containing bioactive constituents such as thymoquinone. Extracts of NS improve performance and reduce enteropathogen colonization in poultry and small ruminants, but studies with swine are lacking. In two different studies oral administration of NS extracts at doses equivalent to 0, 1.5 and 4.5g kg(-1) diet was assessed on piglet performance and intestinal carriage of wildtype Escherichia coli and Campylobacter, and Salmonella Typhimurium. RESULTSWildtype E. coli populations in the jejunal and rectal content collected 9days after treatment began were decreased (P0.05). Populations recovered from pigs treated with extract at 1.5 and 4.5g kg(-1) diet were 0.72-1.31 log(10) units lower than the controls (ranging from 6.05 to 6.61 log(10) CFU g(-1)). Wildtype Campylobacter and Salmonella Typhimurium were unaffected by NS treatment. Feed efficiency over the 9days improved linearly (P<0.05) from 3.88 with 0 NS-treated pigs to 1.47 and 1.41 with pigs treated with NS at 1.5 and 4.5g kg(-1) diet, respectively, possibly due to high glutamine/glutamic acid content of the NS extract. CONCLUSIONNS supplementation of weanling pigs improved feed efficiency and helped control intestinal E. coli during this vulnerable production phase.en
dc.publisherWiley, Hoboken
dc.relationPork Checkoff (National Pork Board) [58-3091-6-021]
dc.relationUnited States Department of Agriculture, Foreign Agricultural Service's Norman E Borlaug International Agricultural Science and Technology Fellowship Program
dc.relationNorman E Borlaug Institute for International Agriculture at Texas AM University
dc.relationUS Department of Agriculture, Agricultural Research ServiceUnited States Department of Agriculture (USDA)
dc.rightsrestrictedAccess
dc.sourceJournal of The Science of Food and Agriculture
dc.subjectalternative antibioticen
dc.subjectEscherichia colien
dc.subjectfeed conversion ratioen
dc.subjectfeed supplementen
dc.subjectswineen
dc.subjectweanling pigsen
dc.titleNigella sativa L. as an alternative antibiotic feed supplement and effect on growth performance in weanling pigsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСwаггертy, Цхристина Л.; Беиер, Росс Ц.; Харвеy, Рогер Б.; Нисбет, Давид Ј.; Aндерсон, Робин Ц.; Хуме, Мицхаел Е.; Цриппен, Таwни Л.; Петрујкић, Бранко; Хе, Хаиqи; Геновесе, Кеннетх Ј.;
dc.citation.volume98
dc.citation.issue8
dc.citation.spage3175
dc.citation.epage3181
dc.citation.other98(8): 3175-3181
dc.citation.rankM21
dc.identifier.wos000431662300037
dc.identifier.doi10.1002/jsfa.8823
dc.identifier.pmid29230814
dc.identifier.scopus2-s2.0-85041340998
dc.identifier.rcubconv_2374
dc.type.versionpublishedVersion


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