Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species
2019
Authors
Pajić, MarkoAleksić, Nevenka
Vejnović, Branislav
Polaček, Vladimir
Novakov, Nikolina
Ostojić-Andrić, Dušica
Stanimirović, Zoran
Article (Published version)
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The influence of certain anticoccidial drugs on oxidative stress in broiler chickens infected with Eimeria species was assessed. There were two untreated (uninfected and infected), and three groups infected and treated with anticoccidials. The first treated group (Ro) was given robenidine, the 2nd a herbal anticoccidial (Herb) and the 3rd the combination of robenidine and the herbal anticoccidial (Ro+Herb). All infected groups were on day 14 challenged with oral inoculation of oocysts. The activities of catalase (CAT), superoxide dismutase (SOD) and glutathione S-transferase (GST), and the concentration of malondialdehyde (MDA) were estimated in blood taken on days 21 and 40. The oocyst numbers were calculated per gram, and chicken body weight and feed conversion ratio (FCR) measured. The activities of CAT, GST and the level of MDA were significantly lower (P<0.05), whilst the activity of SOD was higher in infected chickens treated with anticoccidials (P<0.05) in comparison to those un...treated. The most prominent change in the parameters of oxidative stress was recorded in the Ro+Herb group. In chickens treated with anticoccidials body weight was significantly higher (P<0.05), and the FCR and the oocyst counts significantly lower (P<0.05) than in untreated chickens. Oocyst counts were lower in the Ro and Ro+Herb groups than in the Herb group. Our study demonstrated that both anticoccidial substances exerted antioxidant and anticoccidial effects.
Keywords:
Broilers / ROS / Coccidia / Robenidine / Herbal anticoccidialSource:
Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 2019, 25, 3, 379-385Publisher:
- Kafkas Univ, Veteriner Fakultesi Dergisi, Kars
Funding / projects:
- Molecular genetic and ecophysiological researches on the protection of autochthonous animal genetic resources, sustaining domestic animals’ welfare, health and reproduction, and safe food production (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46002)
- Research on pharmacological characteristics of antimicrobial agents, introduction of new technological solutions and alternative prophylactic methods with the purpose to improve control of infectious animal disease (RS-MESTD-Technological Development (TD or TR)-31071)
DOI: 10.9775/kvfd.2018.21021
ISSN: 1300-6045
WoS: 000460503100014
Scopus: 2-s2.0-85067499046
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Fakultet veterinarske medicineTY - JOUR AU - Pajić, Marko AU - Aleksić, Nevenka AU - Vejnović, Branislav AU - Polaček, Vladimir AU - Novakov, Nikolina AU - Ostojić-Andrić, Dušica AU - Stanimirović, Zoran PY - 2019 UR - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1733 AB - The influence of certain anticoccidial drugs on oxidative stress in broiler chickens infected with Eimeria species was assessed. There were two untreated (uninfected and infected), and three groups infected and treated with anticoccidials. The first treated group (Ro) was given robenidine, the 2nd a herbal anticoccidial (Herb) and the 3rd the combination of robenidine and the herbal anticoccidial (Ro+Herb). All infected groups were on day 14 challenged with oral inoculation of oocysts. The activities of catalase (CAT), superoxide dismutase (SOD) and glutathione S-transferase (GST), and the concentration of malondialdehyde (MDA) were estimated in blood taken on days 21 and 40. The oocyst numbers were calculated per gram, and chicken body weight and feed conversion ratio (FCR) measured. The activities of CAT, GST and the level of MDA were significantly lower (P<0.05), whilst the activity of SOD was higher in infected chickens treated with anticoccidials (P<0.05) in comparison to those untreated. The most prominent change in the parameters of oxidative stress was recorded in the Ro+Herb group. In chickens treated with anticoccidials body weight was significantly higher (P<0.05), and the FCR and the oocyst counts significantly lower (P<0.05) than in untreated chickens. Oocyst counts were lower in the Ro and Ro+Herb groups than in the Herb group. Our study demonstrated that both anticoccidial substances exerted antioxidant and anticoccidial effects. PB - Kafkas Univ, Veteriner Fakultesi Dergisi, Kars T2 - Kafkas Üniversitesi Veteriner Fakültesi Dergisi T1 - Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species VL - 25 IS - 3 SP - 379 EP - 385 DO - 10.9775/kvfd.2018.21021 ER -
@article{ author = "Pajić, Marko and Aleksić, Nevenka and Vejnović, Branislav and Polaček, Vladimir and Novakov, Nikolina and Ostojić-Andrić, Dušica and Stanimirović, Zoran", year = "2019", abstract = "The influence of certain anticoccidial drugs on oxidative stress in broiler chickens infected with Eimeria species was assessed. There were two untreated (uninfected and infected), and three groups infected and treated with anticoccidials. The first treated group (Ro) was given robenidine, the 2nd a herbal anticoccidial (Herb) and the 3rd the combination of robenidine and the herbal anticoccidial (Ro+Herb). All infected groups were on day 14 challenged with oral inoculation of oocysts. The activities of catalase (CAT), superoxide dismutase (SOD) and glutathione S-transferase (GST), and the concentration of malondialdehyde (MDA) were estimated in blood taken on days 21 and 40. The oocyst numbers were calculated per gram, and chicken body weight and feed conversion ratio (FCR) measured. The activities of CAT, GST and the level of MDA were significantly lower (P<0.05), whilst the activity of SOD was higher in infected chickens treated with anticoccidials (P<0.05) in comparison to those untreated. The most prominent change in the parameters of oxidative stress was recorded in the Ro+Herb group. In chickens treated with anticoccidials body weight was significantly higher (P<0.05), and the FCR and the oocyst counts significantly lower (P<0.05) than in untreated chickens. Oocyst counts were lower in the Ro and Ro+Herb groups than in the Herb group. Our study demonstrated that both anticoccidial substances exerted antioxidant and anticoccidial effects.", publisher = "Kafkas Univ, Veteriner Fakultesi Dergisi, Kars", journal = "Kafkas Üniversitesi Veteriner Fakültesi Dergisi", title = "Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species", volume = "25", number = "3", pages = "379-385", doi = "10.9775/kvfd.2018.21021" }
Pajić, M., Aleksić, N., Vejnović, B., Polaček, V., Novakov, N., Ostojić-Andrić, D.,& Stanimirović, Z.. (2019). Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species. in Kafkas Üniversitesi Veteriner Fakültesi Dergisi Kafkas Univ, Veteriner Fakultesi Dergisi, Kars., 25(3), 379-385. https://doi.org/10.9775/kvfd.2018.21021
Pajić M, Aleksić N, Vejnović B, Polaček V, Novakov N, Ostojić-Andrić D, Stanimirović Z. Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species. in Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2019;25(3):379-385. doi:10.9775/kvfd.2018.21021 .
Pajić, Marko, Aleksić, Nevenka, Vejnović, Branislav, Polaček, Vladimir, Novakov, Nikolina, Ostojić-Andrić, Dušica, Stanimirović, Zoran, "Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species" in Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 25, no. 3 (2019):379-385, https://doi.org/10.9775/kvfd.2018.21021 . .