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dc.creatorMitrović, Branislava
dc.creatorStojanović, Mirjana
dc.creatorSekulić, Zivko
dc.creatorAndrić, Velibor
dc.creatorVićentijević, Mihajlo
dc.creatorVranješ, Borjana
dc.date.accessioned2020-06-03T14:34:13Z
dc.date.available2020-06-03T14:34:13Z
dc.date.issued2019
dc.identifier.issn0301-634X
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/1749
dc.description.abstractThe aim of this study was to determine the uranium distribution and histopathological changes in broiler organs (kidney, liver, and brain) and muscle after 7 days of contamination with high doses of uranyl nitrate hexahydrate (UN), and the protective efficiency of three different mineral adsorbents (organobentonite, organozeolite, and sepiolite). During the 7 days, the UN administration was 50mg per day, and administration of adsorbents was 2g per day immediately after UN. In control group where broilers received only UN, histopathological changes such as necrosis of intestinal villi, oedema, vacuolisation and abruption of epithelial cells in renal tubules, oedema and vacuolisation of the cytoplasm of hepatocytes, and dystrophic changes in the neurons of the medulla oblongata were observed. In contrast, when the adsorbents organobentonite, organozeolite, and sepiolite were administered, no histopathological changes were observed in liver and brain. The investigated adsorbents showed the highest protective effects in liver (80-92%), compared to the kidney (77-86%), brain (37-64%), and meat (31-63%).en
dc.publisherSpringer, New York
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31003/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/34013/RS//
dc.rightsrestrictedAccess
dc.sourceRadiation and Environmental Biophysics
dc.subjectUranyl nitrateen
dc.subjectBroilersen
dc.subjectToxicityen
dc.subjectHistopathological changesen
dc.subjectAdsorbentsen
dc.titleToxicity of high uranium doses in broilers and protection with mineral adsorbentsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractВрањеш, Борјана; Вићентијевић, Михајло; Секулић, Зивко; Стојановић, Мирјана; Aндрић, Велибор; Митровић, Бранислава;
dc.citation.volume58
dc.citation.issue3
dc.citation.spage385
dc.citation.epage391
dc.citation.other58(3): 385-391
dc.citation.rankM23
dc.identifier.wos000474439000007
dc.identifier.doi10.1007/s00411-019-00790-5
dc.identifier.pmid30972493
dc.identifier.scopus2-s2.0-85068765195
dc.identifier.rcubconv_2494
dc.type.versionpublishedVersion


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