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dc.creatorBauer, Benjamin W.
dc.creatorRadovanović, Anita
dc.creatorWillson, Nicky-Lee
dc.creatorBajagai, Yadav Sharma
dc.creatorThi, Thu Hao Van
dc.creatorMoore, Robert J.
dc.creatorStanley, Dragana
dc.date.accessioned2020-06-03T14:35:12Z
dc.date.available2020-06-03T14:35:12Z
dc.date.issued2019
dc.identifier.issn2405-8440
dc.identifier.urihttp://vet-erinar.vet.bg.ac.rs/handle/123456789/1763
dc.description.abstractProphylactic use of antibiotics in poultry diets has been identified as a problematic practice because of its potential to exacerbate the spread of antibiotic resistance to human pathogens. A range of countries have opted to completely ban the use of antibiotics in animal feed. The animal production industries are looking for alternative ways to effectively control pathogens while providing the performance benefits previously secured by antibiotics in feed. Here, we present evidence that oregano (Origanum vulgare) could be a potential alternative for pathogen control in the poultry industry. Broiler diets were supplemented with oregano powder (0%, 0.5%, 1%, and 2%) for six weeks. The capacity for pathogen control was estimated by microbiota profiling of the jejunum, ileum, and caecum content, and in the faeces, by 16S rRNA gene amplicon sequencing. The concentrations of short-chain fatty acids in the caecal content were also measured, as were villus/crypt parameters in the ileum. There were no differences among treatments in weight gain, feed intake, or the concentration of short-chain fatty acids. The height, width, and the surface area of villi in the ileum were not influenced by oregano addition. However, 1% and 2% of oregano produced a significant increase in the villus height to crypt depth ratio. There were no visible histopathological changes in the liver in control and treated groups. Although oregano had no significant effect on overall microbial diversity and gross composition, some specific genera, like Proteus, Klebsiella and Staphylococcus, which include known pathogens, were reduced in relative abundance by oregano treatment. Bifidobacterium, recognized as a beneficial and probiotic genus, was also suppressed by the oregano treatment.en
dc.publisherElsevier Sci Ltd, Oxford
dc.relationPoultry CRC under the Australian Government's Cooperative Research Centres ProgramAustralian GovernmentDepartment of Industry, Innovation and ScienceCooperative Research Centres (CRC) Programme
dc.rightsopenAccess
dc.sourceHeliyon
dc.subjectFood microbiologyen
dc.subjectAnimal scienceen
dc.subjectMicrobiologyen
dc.subjectPublic healthen
dc.subjectGastrointestinal systemen
dc.subjectOreganoen
dc.subjectChickenen
dc.subjectMicrobiotaen
dc.subjectAntibiotic alternativeen
dc.titleOregano: A potential prophylactic treatment for the intestinal microbiotaen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractТхи, Тху Хао Ван; Бајагаи, Yадав Схарма; Станлеy, Драгана; Wиллсон, Ницкy-Лее; Радовановић, Aнита; Мооре, Роберт Ј.; Бауер, Бењамин W.;
dc.citation.volume5
dc.citation.issue10
dc.citation.spagee02625
dc.citation.other5(10): e02625
dc.identifier.wos000494641300128
dc.identifier.doi10.1016/j.heliyon.2019.e02625
dc.identifier.pmid31667426
dc.identifier.scopus2-s2.0-85073031224
dc.identifier.fulltexthttp://veterinar.vet.bg.ac.rs/bitstream/id/724/1762.pdf
dc.identifier.rcubconv_2521
dc.type.versionpublishedVersion


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