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dc.creatorBozic (Durdevic), Biljana
dc.creatorVučićević, Ivana
dc.creatorPolaček, Vladimir
dc.creatorVasković, Nikola
dc.creatorPetrović, Tamaš
dc.creatorPajić, Marko
dc.creatorAleksić-Kovačević, Sanja
dc.date.accessioned2020-06-03T14:35:42Z
dc.date.available2020-06-03T14:35:42Z
dc.date.issued2019
dc.identifier.issn0505-401X
dc.identifier.urihttps://vet-erinar.vet.bg.ac.rs/handle/123456789/1770
dc.description.abstractThe aim of this study was to compare pathological lesions and viral antigen expression in the organs of mute swans (Cygnus olor) naturally infected with highly pathogenic avian influenza virus subtypes H5N1 and H5N8. The examination was conducted on the carcasses of 22 mute swans which died during the avian influenza outbreaks in Serbia in 2006 and 2016-2017. Avian influenza virus subtype H5N8 isolated from mute swans in 2016-2017 was clustered within the 2.3.4.4 Glade group B. After necropsy, lung, liver, spleen, pancreas, kidney and brain tissues were sampled for histopathology and immunohistochemical examination. Avian influenza virus nucleoprotein polyclonal antibodies were used for detecting the viral antigen in the examined tissues. The most significant gross lesions were necrosis and haemorrhages in the pancreas. Major histological lesions were multifocal necroses in the pancreas, spleen and liver, non-purulent encephalitis, lung congestion and oedema. Immunohistochemical demonstration of HPAIV nucleoprotein in pancreas and brain was strongly consistent with histological lesions in both infected groups. Our findings showed that pancreas was the most affected organ in all examined mute swans. In addition to increased mortality rate, similar pathological findings were detected in mute swans naturally infected with highly pathogenic avian influenza viruses H5N1 and H5N8.en
dc.publisherIst Zooprofilattico Sperimentale Abruzzo & Molise G Caporale-Izs A&M, Teramo
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31011/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31084/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46002/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.sourceVeterinaria Italiana
dc.subjectH5N1en
dc.subjectH5N8en
dc.subjectPathological lesionsen
dc.subjectMute swansen
dc.subjectPancreasen
dc.subjectSerbiaen
dc.titleComparative pathological findings in mute swans (Cygnus olor) naturally infected with highly pathogenic Avian influenza viruses H5N1 and H5N8 in Serbiaen
dc.typearticle
dc.rights.licenseBY-NC
dcterms.abstractВучићевић, Ивана; Бозиц (Дурдевиц), Биљана; Васковић, Никола; Пајић, Марко; Полачек, Владимир; Петровић, Тамаш; Aлексић-Ковачевић, Сања;
dc.citation.volume55
dc.citation.issue1
dc.citation.spage95
dc.citation.epage101
dc.citation.other55(1): 95-101
dc.citation.rankM22
dc.identifier.wos000496972400011
dc.identifier.doi10.12834/VetIt.1463.7919.2
dc.identifier.pmid30951187
dc.identifier.scopus2-s2.0-85064313511
dc.identifier.fulltexthttps://vet-erinar.vet.bg.ac.rs/bitstream/id/731/1769.pdf
dc.type.versionpublishedVersion


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